PANGRAF 5.0 CAPSULE 10'S
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PANGRAF 5.0 CAPSULE 10'S
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PANGRAF 5.0 CAPSULE 10'S

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PANGRAF 5.0 CAPSULE 10'S

By MANKIND PHARMA LIMITED

MRP

2502.5

₹1844

26.31 % OFF

₹184.4 Only /

CAPSULE

10

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Composition

Product DetailsArrow

About PANGRAF 5.0 CAPSULE 10'S

  • PANGRAF 5.0 CAPSULE 10'S contains the active substance Tacrolimus. It belongs to a class of medications called calcineurin inhibitors and functions as an immunosuppressant. This capsule is prescribed alongside other medications to prevent organ transplant rejection in individuals who have undergone liver, kidney, heart, or other organ transplants. Its primary function is to control the body’s immune response, enabling it to accept the transplanted organ and minimize the risk of rejection.
  • Before taking PANGRAF 5.0 CAPSULE 10'S, it's important to be aware of certain precautions. Do not take this medication if you have a known allergy to tacrolimus or any of the other ingredients it contains. Additionally, inform your physician if you have any known allergies to any group of antibiotics. It's crucial to inform your doctor about any pre-existing liver or heart conditions before commencing treatment with this medication. Promptly notify your physician if you experience any concerning symptoms after taking this medicine, such as fever, unexplained bruising under the skin (which may appear as red dots), persistent tiredness, confusion, yellowing of the skin or eyes, reduced urine output, vision loss, or seizures.
  • While taking PANGRAF 5.0 CAPSULE 10'S, it's advisable to limit exposure to sunlight and UV light by wearing appropriate protective clothing and using sunscreen with a high sun protection factor. This is due to the potential risk of malignant skin changes associated with immunosuppressive therapy. This medicine may also cause diarrhea; therefore, inform your physician if you experience diarrhea for more than a day. If you require any vaccinations, consult your doctor before receiving them to ensure they are safe and appropriate while taking this medication. Regular monitoring and communication with your healthcare provider are essential to manage potential side effects and ensure the effectiveness of your treatment.
  • It is also essential to maintain optimal hydration and electrolyte balance while taking this medication, especially if diarrhea occurs. Avoid consuming grapefruit or grapefruit juice, as it can interact with Tacrolimus and affect its concentration in the body. Be vigilant about any signs of infection, such as fever, sore throat, or cough, and seek medical attention promptly if they occur, as this medication can weaken your immune system.
  • Adherence to the prescribed dosage and schedule is crucial for the success of your treatment. Do not abruptly stop taking this medication without consulting your doctor, as it could lead to organ rejection. Your doctor will regularly monitor your Tacrolimus levels through blood tests to ensure they are within the therapeutic range. Report any new medications or supplements you are taking to your doctor, as they may interact with Tacrolimus.

Uses of PANGRAF 5.0 CAPSULE 10'S

  • Prevent organ transplant rejections. PANGRAF 5.0 CAPSULE 10'S helps in preventing organ rejection by the body after transplant.

Side Effects of PANGRAF 5.0 CAPSULE 10'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Swelling in the arm or leg
  • Hair loss
  • Itchy skin
  • Constipation, diarrhea
  • Nausea, vomiting
  • Anemia
  • Headache
  • Cough
  • Increased or decreased heartbeats
  • GI bleeding
  • Liver Injury
  • Seizure
  • Acute kidney failure
  • Lung infection or respiratory problems

Safety Advice for PANGRAF 5.0 CAPSULE 10'SArrow

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Pregnancy

CONSULT YOUR DOCTOR

Based on animal studies, PANGRAF 5.0 CAPSULE 10'S can cause harmful effects on the baby. Inform your physician if you are pregnant, suspecting pregnancy or planning to get pregnant before initiating the treatment.

Dosage of PANGRAF 5.0 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with PANGRAF 5.0 CAPSULE 10'S, considering your specific medical condition, its severity, and other relevant factors. It is crucial to always take PANGRAF 5.0 CAPSULE 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting your physician.
  • To ensure optimal absorption and effectiveness, PANGRAF 5.0 CAPSULE 10'S should be swallowed whole with a glass of water. Avoid opening, breaking, crushing, or chewing the capsules, as this could affect how the medication is released and absorbed by your body.
  • For the best results, take PANGRAF 5.0 CAPSULE 10'S on an empty stomach, ideally at least 1 hour before a meal or 2 to 3 hours after eating. This helps to minimize potential interactions with food and ensures that the medication is absorbed properly into your bloodstream. Consistency in timing is important for maintaining stable drug levels in your system.
  • If you have any questions or concerns regarding the dosage or administration of PANGRAF 5.0 CAPSULE 10'S, please consult your doctor or pharmacist for clarification.

How to store PANGRAF 5.0 CAPSULE 10'S?Arrow

  • Keep PANGRAF 5MG CAP 1X10 away from the reach of children and pets.
  • Store PANGRAF 5MG CAP 1X10 at room temperature.

Benefits of PANGRAF 5.0 CAPSULE 10'SArrow

  • PANGRAF 5.0 CAPSULE 10'S is a medication that helps to suppress the immune system. It achieves this by specifically targeting and inhibiting the activation and proliferation of T-lymphocytes. These cells play a crucial role in the body's immune response, and by reducing their activity, PANGRAF 5.0 CAPSULE 10'S helps to prevent the body from attacking itself in cases of organ transplantation or autoimmune diseases.
  • The drug's mechanism of action involves binding to an intracellular protein known as FKBP-12. This binding process leads to the formation of a complex called tacrolimus-FKBP. This complex then inhibits calcineurin phosphatase, an enzyme essential for T cell activation. By blocking calcineurin, PANGRAF 5.0 CAPSULE 10'S effectively reduces the formation of T cells, leading to a suppressed immune response. This controlled immunosuppression is vital for preventing organ rejection after transplantation and managing autoimmune disorders where the immune system mistakenly attacks the body's own tissues.
  • Furthermore, PANGRAF 5.0 CAPSULE 10'S also impacts the B-cell response, which is dependent on T-helper cells. By suppressing T-helper cell activity, the medication indirectly reduces the activity of B-cells. B-cells are responsible for producing antibodies, and their reduced activity further contributes to the overall immunosuppressive effect of the drug.

How to use PANGRAF 5.0 CAPSULE 10'SArrow

  • Your doctor will determine the appropriate dosage and duration of treatment with PANGRAF 5.0 CAPSULE 10'S based on your specific medical condition, its severity, and other individual health factors. It is crucial to strictly adhere to your doctor's prescribed instructions for taking this medication.
  • To ensure optimal absorption and effectiveness, always consume PANGRAF 5.0 CAPSULE 10'S exactly as directed by your healthcare provider. Avoid opening, breaking, crushing, or chewing the capsules. Instead, swallow the capsule whole with a full glass of water.
  • For best results, take PANGRAF 5.0 CAPSULE 10'S on an empty stomach. This typically means taking it at least one hour before a meal or waiting two to three hours after eating to take the capsule. This helps to minimize any potential interactions with food that could affect how the medication is absorbed into your system.
  • If you have any questions or concerns regarding the proper way to take PANGRAF 5.0 CAPSULE 10'S, don't hesitate to ask your doctor or pharmacist for clarification. They can provide personalized guidance based on your individual needs and circumstances. Following these instructions carefully will help you get the most benefit from your medication and minimize the risk of side effects.

FAQs

What if I missed a dose of PANGRAF 5.0 CAPSULE 10'S?Arrow

Try to take it as soon as possible, you remember. If it is time for the next dose, skip the missed dose and follow the regular schedule. Do not double the dose to make up for the forgotten dose.

What should you not use with PANGRAF 5.0 CAPSULE 10'S?Arrow

Avoid taking mycophenolic acid-containing products, nelfinavir, sirolimus, cyclosporine, antibiotics, and antiviral medications. Inform your healthcare provider about any prescription medicines, over-the-counter medications, or vitamin or herbal supplements you have taken before the treatment.

How long do I need to take PANGRAF 5.0 CAPSULE 10'S after a transplant?Arrow

The duration of PANGRAF 5.0 CAPSULE 10'S treatment after a transplant can vary depending on various factors, including the type of organ transplant and the individual's response to the medication. In most cases, PANGRAF 5.0 CAPSULE 10'S is taken long-term to prevent organ rejection, but the healthcare professional will determine the specific duration.

Can PANGRAF 5.0 CAPSULE 10'S increase the risk of infections?Arrow

Yes, PANGRAF 5.0 CAPSULE 10'S can suppress the immune system, which may increase the risk of infections. It is important to take precautions to minimize the risk of infections, such as practicing good hygiene, avoiding close contact with individuals who are sick, and getting recommended vaccinations.

Can PANGRAF 5.0 CAPSULE 10'S affect kidney function?Arrow

PANGRAF 5.0 CAPSULE 10'S must be cautiously administered in patients with kidney diseases because it can potentially affect kidney function. Regular monitoring of kidney function through blood tests is typically done to detect any changes or potential complications. Inform your physician if you have kidney problems before initiating the therapy.

Should I follow any dietary restrictions while taking PANGRAF 5.0 CAPSULE 10'S?Arrow

PANGRAF 5.0 CAPSULE 10'S can interact with certain foods and beverages, particularly grapefruit and grapefruit juice, which may increase the levels of this medicine in the blood. Discussing dietary restrictions and potential interactions with your healthcare provider is important.

How does PANGRAF 5.0 CAPSULE 10'S interact with other drugs?Arrow

PANGRAF 5.0 CAPSULE 10'S can negatively interact with other drugs. Always tell your doctor about all medications you are taking to avoid potential interactions.

What advice should I follow while using PANGRAF 5.0 CAPSULE 10'S?Arrow

Do not eat grapefruit or drink grapefruit juice while you are using PANGRAF 5.0 CAPSULE 10'S. Do not drink alcohol while you are using this medicine. This medicine may interfere with the vaccine. Ask your healthcare professional before getting a flu shot or other vaccines. You must take this medicine as a long-term treatment to prevent rejection of your transplanted organ. Do not stop taking this medicine without informing your doctor. Your doctor may advise you to take certain tests to monitor the effectiveness and side effects of the therapy. Keep all your appointments regularly.

What is PANGRAF 5.0 CAPSULE 10'S made of?Arrow

PANGRAF 5.0 CAPSULE 10'S is made of TACROLIMUS.

For which ailments/diseases/conditions is PANGRAF 5.0 CAPSULE 10'S prescribed?Arrow

PANGRAF 5.0 CAPSULE 10'S is used for treating ailments related to Nephrology and Infectious Diseases.

References

Book Icon

Prograf 0.5mg Hard Capsules - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published December 2022.

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Highlights Of Prescribing Information, Prograf ® (Tacrolimus) Capsules PROGRAF ® (Tacrolimus) Injection, (for Intravenous Use).

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Ratings & Review

Awesome

Pankaj Patel

Reviewed on 13-06-2023

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(5/5)

Awesome experience every time i get medicine on time and they have delivery on time also staff are very cooperative and knowledgeable

Tarun Ezava

Reviewed on 22-06-2023

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(5/5)

Amazing service and customer friendly

Deepak Patel

Reviewed on 05-11-2022

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(3/5)

Good place with excellent service and good customer service

Kunal Patel

Reviewed on 13-05-2023

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(5/5)

Good service , great discount, I am regular customer

Gohil Aadityaraj

Reviewed on 27-07-2023

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(5/5)


Marketer / Manufacturer Details

MANKIND PHARMA LIMITED

Country of Origin -

India

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PANGRAF 5.0 CAPSULE 10'S

PANGRAF 5.0 CAPSULE 10'S

MRP

2502.5

₹1844

26.31 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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