PICLIB 125MG CAPSULE 21'S
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PICLIB 125MG CAPSULE 21'S
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PICLIB 125MG CAPSULE 21'S

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PICLIB 125MG CAPSULE 21'S

By HETERO HEALTHCARE LTD

MRP

₹

7801.5

₹2438

68.75 % OFF

₹116.1 Only /

CAPSULE

10

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About PICLIB 125MG CAPSULE 21'S

  • PICLIB 125MG CAPSULE 21'S contains palbociclib, a targeted therapy belonging to the cyclin-dependent kinase inhibitor class of anticancer medications. It is prescribed for hormone receptor-positive, human epidermal growth factor 2-negative advanced or metastatic breast cancer (cancer that has spread to other parts of the body). Cancer is characterized by uncontrolled and abnormal cell multiplication. This medication is administered in conjunction with other anticancer drugs.
  • Common side effects associated with PICLIB 125MG CAPSULE 21'S may include nausea, vomiting, diarrhea, fatigue, hair loss, dry skin, rash, infections, nosebleeds, decreased appetite, low blood cell counts, swelling of the lips and mouth, changes in taste, dry eyes, blurred vision, and increased tearing. If any of these side effects become bothersome or persist, inform your doctor.
  • It's important to inform your healthcare provider about any allergies you have, especially to palbociclib or any other ingredients in PICLIB 125MG CAPSULE 21'S. Before starting this medication, tell your doctor if you have any signs of infection (such as fever, chills, or sore throat), liver disorders, kidney disorders, or intolerance to certain sugars. If you experience symptoms like dry cough, chest pain, or difficulty breathing, seek immediate medical attention as these could indicate lung inflammation. Disclose all medications you are currently taking, including supplements and herbal remedies, before commencing treatment with this drug. Use effective contraception during treatment and for at least three weeks after the last dose. PICLIB 125MG CAPSULE 21'S is not recommended for children and adolescents under the age of 18. Palbociclib functions by selectively inhibiting cyclin-dependent kinases 4 and 6 (CDK4/6). These kinases play a crucial role in promoting cell division. By blocking CDK4/6, palbociclib helps to slow down the growth and spread of cancer cells in hormone receptor-positive breast cancer.
  • Regular monitoring of blood cell counts is essential during treatment with PICLIB 125MG CAPSULE 21'S, as it can cause a decrease in white blood cells, red blood cells, and platelets. Patients should also be vigilant for signs of infection and report any fever, chills, or other symptoms promptly to their healthcare provider. Dosage adjustments may be necessary based on individual patient response and tolerability. The medication should be taken with food to improve absorption. Always adhere to your doctor's prescribed dosage and schedule.

Uses of PICLIB 125MG CAPSULE 21'S

  • Treatment of hormone receptor (HR)-positive, human epidermal growth factor 2 (HER2)-negative advanced or metastatic breast cancer. This medication is prescribed for individuals diagnosed with advanced or metastatic breast cancer that exhibits hormone receptor positivity and human epidermal growth factor 2 negativity.

Side Effects of PICLIB 125MG CAPSULE 21'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Here are some potential side effects associated with PICLIB 125MG CAPSULE 21'S:

  • Blood disorder (fever, chills, shortness of breath, weakness, bleeding, or bruising)
  • Lung inflammation (chest pain, dry cough, or difficulty breathing)
  • Tiredness
  • Hair loss
  • Dry skin, rash
  • Infections
  • Low blood cell counts
  • Decreased of appetite
  • Nausea, vomiting
  • Diarrhea
  • Swelling of lips and mouth
  • Changes in taste
  • Nose bleed
  • Dry eye, blurred vision, increased tearing

Safety Advice for PICLIB 125MG CAPSULE 21'SArrow

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Pregnancy

UNSAFE

It is not recommended to take PICLIB 125MG CAPSULE 21'S during pregnancy as it can harm the unborn baby. Women with childbearing potential should use effective contraceptives during treatment and for at least three weeks after treatment.

Dosage of PICLIB 125MG CAPSULE 21'SArrow

  • Take PICLIB 125MG CAPSULE 21'S exactly as prescribed by your doctor. It's crucial to adhere to the prescribed dosage and schedule for optimal results.
  • This medication is typically taken once a day, and it's recommended to take it at the same time each day to maintain a consistent level of the drug in your system. Consistency in timing helps ensure the medication works effectively.
  • Always take PICLIB 125MG CAPSULE 21'S with food. Taking it with food can help improve its absorption and reduce the risk of stomach upset. Follow your doctor's instructions regarding food intake while taking this medication.
  • Swallow the capsule whole with a full glass of water. Do not crush, break, or chew the capsule. Altering the capsule's form can affect how the medication is released and absorbed in your body. If you have difficulty swallowing capsules, consult your doctor or pharmacist for alternative options.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. Doubling the dose can lead to potential side effects or complications. Contact your doctor if you have any concerns about missed doses.
  • Ensure to complete the full course of treatment as prescribed by your doctor, even if you start feeling better. Stopping the medication prematurely can lead to a relapse of your condition or the development of antibiotic resistance. Always follow your doctor's instructions for the duration of treatment.
  • It is important to discuss any concerns or questions you have about PICLIB 125MG CAPSULE 21'S with your doctor or pharmacist. They can provide you with additional information and guidance tailored to your specific health condition.

How to store PICLIB 125MG CAPSULE 21'S?Arrow

  • Keep PICLIB 125MG CAP 1X21 away from the reach of children and pets.
  • Store PICLIB 125MG CAP 1X21 at room temperature.

Benefits of PICLIB 125MG CAPSULE 21'SArrow

  • PICLIB 125MG CAPSULE 21'S operates by targeting and inhibiting specific proteins known as cyclin-dependent kinases 4 and 6 (CDK4/6). These proteins play a crucial role in regulating the cell cycle, particularly the division and growth of cells. In cancer cells, these proteins are often overactive, leading to uncontrolled proliferation.
  • By selectively blocking CDK4/6, PICLIB 125MG CAPSULE 21'S effectively disrupts the cell cycle progression, preventing the cancer cells from dividing and multiplying. This mechanism of action helps to slow down the growth of the tumor and inhibit the spread of cancer cells to other parts of the body.
  • This targeted approach offers a significant advantage in cancer treatment, as it specifically targets the proteins driving cancer cell growth while minimizing damage to healthy cells. This can lead to fewer side effects compared to traditional chemotherapy. PICLIB 125MG CAPSULE 21'S is often used in combination with other cancer therapies to enhance its effectiveness.

How to use PICLIB 125MG CAPSULE 21'SArrow

  • Always take PICLIB 125MG CAPSULE 21'S exactly as your doctor has prescribed. It's crucial to adhere to their instructions for the best possible outcome.
  • Typically, this medication is taken once daily, and it's recommended to take it at the same time each day to maintain a consistent level in your system. Taking it with food can also help improve absorption and reduce potential stomach upset.
  • When taking PICLIB 125MG CAPSULE 21'S, swallow the capsule whole with a full glass of water. Do not crush, break, or chew the capsule, as this can affect how the medication is released and absorbed by your body. This ensures that the medication is delivered to your system in the way it was intended.
  • If you have any questions or concerns about how to take PICLIB 125MG CAPSULE 21'S, don't hesitate to ask your doctor or pharmacist. They can provide you with personalized guidance and address any specific concerns you may have.

Top Substitutes for PICLIB 125MG CAPSULE 21'S

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PRIMCYV 125MG CAP 1X7DR REDDY'S LABORATORIES LIMITED71394.06122012.49
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PALBO 125MG CAP 1X21ALKEM LABORATORIES LIMITED215742.194880.8615
PICICLIB 125MG CAP 1X21CIPLA PHARMACEUTICAL COMPANY LIMITED215853.364975.3615
WEBACE 125MG CAP 1X21WEMBRACE BIOPHARMA PVT LTD215622.1851009.29
PALENO 125MG CAP 1X21SUN PHARMACEUTICAL INDUSTRIES LTD215811.565230.410
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ISOGEN 125MG CAP 1X21SAMARTH LIFE SCIENCES PRIVATE LIMITED2122968.75563575.47
PALBOTOR 125MG CAP 1X21TORRENT PHARMACEUTICALS LIMITED218906.25570036
ADCILIB 125MG CAP 1X21ADLEY FORMULATIONS PRIVATE LIMITED217837.5585225.33
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CELOCLIB 125MG CAP 1X21CELON LABORATORIES LTD2112656.25620051.01
HORMOCLIB 125MG CAP 1X21ABBOTT HEALTH CARE PRIVATE LIMITED2116770715557.33
CYDEKIN 125MG CAP 1X21INTAS PHARMACEUTICALS LIMITED217968.7572259.33
BRESPAL 125MG CAP 1X21AUREATE HEALTHCARE PRIVATE LIMITED218812.57490.6215
PRIMCYV IH 125MG CAP 1X21DR REDDY'S LABORATORIES LIMITED2113593.75125257.86
PALBACE 125MG TAB 1X21PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED2121093.751855012.06
PRIMCYV 125MG CAP 1X21DR REDDY'S LABORATORIES LIMITED2189062.57125020
PALBOJAS 125MG CAP 1X21JASGUR LIFE SCIENCES LLP21260024376.27

FAQs

Is PICLIB 125MG CAPSULE 21'S a targeted therapy?Arrow

Yes, PICLIB 125MG CAPSULE 21'S is a targeted therapy. This medication belongs to the class of cyclin-dependent kinase inhibitors.

Do you lose hair on PICLIB 125MG CAPSULE 21'S?Arrow

Yes, Taking PICLIB 125MG CAPSULE 21'S can cause hair loss or hair thinning. It is one of the side effects of this medication. Consult your doctor if any side effects disturb you.

Can children use PICLIB 125MG CAPSULE 21'S?Arrow

No, PICLIB 125MG CAPSULE 21'S is not recommended for adolescents and children under 18.

Does PICLIB 125MG CAPSULE 21'S affect fertility?Arrow

Yes, PICLIB 125MG CAPSULE 21'S may reduce fertility in men. It may affect your ability to become a father and a child. Hence, men should consider sperm preservation before taking this medication.

Does PICLIB 125MG CAPSULE 21'S affect blood cell count?Arrow

PICLIB 125MG CAPSULE 21'S might reduce the number of white blood cells and weaken the immune system. It could lead to an increase in the risk of infections. Regular blood tests while taking PICLIB 125MG CAPSULE 21'S are advised.

Are there any drug interactions with PICLIB 125MG CAPSULE 21'S?Arrow

There are no known drug interactions with PICLIB 125MG CAPSULE 21'S.

What advice should I follow while taking PICLIB 125MG CAPSULE 21'S?Arrow

During PICLIB 125MG CAPSULE 21'S treatment, it is advised to avoid grapefruit and its juices and preparations containing St. John's wort. It is recommended to use effective birth control while receiving treatment as well as for at least three weeks after the final dose for females and at least fourteen weeks after the final dose for males. This medication may reduce fertility, so discuss with the physician if you have any concerns. Your doctor may recommend regular blood tests to determine whether PICLIB 125MG CAPSULE 21'S affects your blood cells.

What molecule/combination is used for making PICLIB 125MG CAPSULE 21'S?Arrow

PALBOCICLIB is molecule/combination used for making PICLIB 125MG CAPSULE 21'S.

For what ailments/diseases/conditions is PICLIB 125MG CAPSULE 21'S prescribed?Arrow

PICLIB 125MG CAPSULE 21'S is prescribed for ailments/diseases/conditions related to Oncology.

References

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Pfizer Limited, Electronic medicines compendium (emc)

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Pfizer Labs, US Food and Drug Administration

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Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy

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Palbace; Pfizer

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Reviewed on 08-11-2022

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Marketer / Manufacturer Details

HETERO HEALTHCARE LTD

Country of Origin -

India

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PICLIB 125MG CAPSULE 21'S

MRP

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₹2438

68.75 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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