PICLIN ORAL SOLUTION 150 ML

How PICLIN ORAL SOLUTION 150 ML Works

• PICLIN ORAL SOLUTION 150 ML is a laxative medication primarily used to treat constipation. Its effectiveness stems from its key ingredient, sodium picosulfate, which works by stimulating bowel movements. After oral administration, sodium picosulfate is converted by gut bacteria in the colon into its active form, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM). This conversion is crucial for the drug's action, as sodium picosulfate itself is relatively inactive.
• BHPM then stimulates the sensory nerve endings in the wall of the colon. This stimulation increases peristaltic activity, the wave-like muscle contractions that move waste through the intestines. By increasing peristalsis, PICLIN ORAL SOLUTION 150 ML promotes the propulsion of fecal matter towards the rectum, facilitating bowel evacuation. This process typically occurs within 6 to 12 hours after taking the medication, making it suitable for overnight relief of constipation.
• Furthermore, PICLIN ORAL SOLUTION 150 ML also reduces water absorption from the colon, which helps to soften the stool. Softer stools are easier to pass, further alleviating constipation symptoms. The combined effects of increased peristalsis and softened stool make PICLIN ORAL SOLUTION 150 ML an effective treatment for occasional constipation. It's important to note that while PICLIN ORAL SOLUTION 150 ML provides relief from constipation, it should not be used for prolonged periods without consulting a healthcare professional, as long-term use of laxatives can lead to dependency and other adverse effects. Maintaining a balanced diet rich in fiber and adequate hydration are also crucial for preventing constipation in the long run.
• In summary, PICLIN ORAL SOLUTION 150 ML's mechanism of action involves the bacterial conversion of sodium picosulfate into BHPM, which then stimulates colonic peristalsis and reduces water absorption, leading to softer stools and easier bowel movements. This dual action effectively relieves constipation within a few hours of administration.

Common side effects of Piclin Oral Solution may include nausea, vomiting, diarrhea, abdominal cramps, and bloating. Less common side effects can include electrolyte imbalance (such as low sodium or potassium), dehydration, dizziness, headache, and skin rashes. In rare cases, severe allergic reactions may occur. If you experience any persistent or severe side effects, discontinue use and consult your doctor immediately.

• If you miss a dose of Piclin Oral Solution, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for the missed one.

• Keep PICLIN ORAL SOLUTION 150ML away from the reach of children and pets.
• Store PICLIN ORAL SOLUTION 150ML at room temperature.

• **Stay Hydrated:** Piclin Oral Solution can cause dehydration. Drink plenty of clear fluids like water, broth, or electrolyte solutions throughout the day to replenish lost fluids. Aim for at least 8-10 glasses of water.
• **Time it Right:** Take Piclin Oral Solution as directed by your doctor, usually the day before your colonoscopy or other procedure. Follow the specific timing instructions provided to ensure optimal bowel preparation. Typically, you will need to split the dose and take half in the evening and the other half the next morning.
• **Understand Potential Side Effects:** Be aware of possible side effects such as nausea, vomiting, abdominal cramping, bloating, and dizziness. If these symptoms become severe or persistent, contact your doctor immediately. Do not take any additional medications to treat these side effects without consulting your physician.
• **Adjust Your Diet:** For best results, follow a clear liquid diet starting at least 24 hours before taking Piclin. Avoid solid foods, milk, alcohol, and red or purple liquids. Clear liquids include water, clear broth, clear fruit juices (apple, white grape), plain tea or coffee (no milk or cream), and clear gelatin. This diet helps to ensure your colon is clear for the procedure.
• **Monitor Your Bowel Movements:** You should experience frequent, watery bowel movements after taking Piclin. This indicates that the solution is working to cleanse your colon. Continue to stay near a restroom until the bowel movements stop. If you do not experience bowel movements within a few hours, contact your doctor.
• **Medication Interactions:** Inform your doctor about all medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Piclin can interact with certain medications, such as diuretics, ACE inhibitors, and NSAIDs. Your doctor may need to adjust your medication schedule or dosage.
• **Electrolyte Imbalance:** Piclin can cause electrolyte imbalances, particularly in individuals with pre-existing kidney or heart conditions, or those taking certain medications. If you experience symptoms of electrolyte imbalance, such as muscle weakness, irregular heartbeat, or confusion, seek immediate medical attention.

• There are no known significant food interactions with Piclin Oral Solution. It can be taken with or without food. However, it's always a good practice to maintain consistency in your diet while taking any medication.