PIOGLIT MF 7.5MG TABLET 10'S

How PIOGLIT MF 7.5MG TABLET 10'S Works

• PIOGLIT MF 7.5MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines two active ingredients: Pioglitazone and Metformin, each working through different mechanisms to lower blood sugar levels and improve insulin sensitivity.
• Pioglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It primarily works by increasing the body's sensitivity to insulin. Insulin is a hormone that helps glucose (sugar) enter cells to be used for energy. In type 2 diabetes, cells become resistant to insulin, leading to elevated blood sugar levels. Pioglitazone activates a receptor called PPARγ (peroxisome proliferator-activated receptor gamma) in fat cells, muscle cells, and the liver. Activation of PPARγ leads to increased expression of genes involved in glucose metabolism and insulin signaling. This results in several beneficial effects: Increased glucose uptake in muscles and fat tissues, Reduced glucose production in the liver, Improved insulin sensitivity throughout the body. By enhancing insulin sensitivity, pioglitazone helps lower blood sugar levels, especially after meals.
• Metformin, on the other hand, is a biguanide. It works primarily by decreasing glucose production in the liver and improving insulin sensitivity. Specifically, Metformin: Reduces hepatic glucose production: The liver is a major source of glucose in the body, especially during fasting. Metformin suppresses the production of glucose in the liver by inhibiting gluconeogenesis (the process of making glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose).Increases insulin sensitivity: Metformin improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to use glucose more effectively. Slows down glucose absorption in the intestines: This helps to reduce the spike in blood sugar levels after meals. By reducing glucose production in the liver and enhancing insulin sensitivity, metformin helps to lower both fasting and postprandial (after-meal) blood sugar levels.
• In combination, Pioglitazone and Metformin provide a complementary approach to managing type 2 diabetes. Pioglitazone improves insulin sensitivity, while metformin reduces glucose production in the liver and enhances insulin action. This dual action helps to achieve better blood sugar control compared to using either medication alone. It's important to note that PIOGLIT MF 7.5MG TABLET 10'S is most effective when used in conjunction with lifestyle modifications, such as a healthy diet and regular exercise.

The following side effects may occur while taking Pioglit MF 7.5mg Tablet: **Common Side Effects:** * Hypoglycemia (low blood sugar) - may occur when used with other diabetes medications. * Gastrointestinal disturbances: Nausea, vomiting, diarrhea, abdominal pain. * Headache * Edema (swelling) - particularly in the legs and ankles. * Weight gain * Upper respiratory tract infection **Uncommon Side Effects:** * Visual disturbances * Joint pain * Fatigue * Anemia * Insomnia **Rare Side Effects:** * Liver problems: Indicated by jaundice (yellowing of skin or eyes), dark urine, or persistent nausea. * Heart failure: Symptoms include shortness of breath, rapid weight gain, and swelling. * Increased risk of bone fractures (particularly in women). * Macular edema (fluid buildup in the macula of the eye). * Allergic reactions: Rash, itching, hives, swelling of the face, lips, or tongue. **Important Note:** This is not an exhaustive list. Report any new or worsening symptoms to your doctor.

• If you miss a dose of PIOGLIT MF 7.5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep PIOGLIT MF 7.5MG TAB 1X10 away from the reach of children and pets.
• Store PIOGLIT MF 7.5MG TAB 1X10 at room temperature.

• Take PIOGLIT MF 7.5MG TABLET 10'S as prescribed by your doctor, usually once or twice daily with meals, to minimize stomach upset and maximize absorption. Consistency is key for maintaining stable blood sugar levels.
• Monitor your blood sugar levels regularly as directed by your healthcare provider. PIOGLIT MF 7.5MG TABLET 10'S helps improve insulin sensitivity, but regular monitoring is crucial for assessing its effectiveness and adjusting your treatment plan if needed. Keep a log to share with your doctor.
• Follow a healthy diet and exercise regularly while taking PIOGLIT MF 7.5MG TABLET 10'S. This medication works best when combined with lifestyle modifications. Focus on balanced meals, portion control, and at least 30 minutes of moderate-intensity exercise most days of the week.
• Be aware of potential side effects, such as weight gain, swelling (edema), or symptoms of hypoglycemia (low blood sugar). Contact your doctor immediately if you experience chest pain, shortness of breath, or severe abdominal pain. Carry a source of quick-acting sugar (glucose tablets or juice) in case of hypoglycemia.
• Inform all your healthcare providers that you are taking PIOGLIT MF 7.5MG TABLET 10'S, especially before any surgery or dental procedures. This medication can interact with other drugs, and your doctor needs to be aware of your complete medical history to ensure safe and effective treatment. Do not stop this medication without consulting your doctor.

• PIOGLIT MF 7.5MG TABLET 10'S can be taken with or without food. However, it is generally recommended to take it with meals to reduce the possibility of gastrointestinal side effects such as nausea or upset stomach. Consistent timing with meals can also aid in maintaining stable blood sugar levels.
• Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis and may also affect blood sugar control. Consult your doctor for specific dietary advice tailored to your condition and treatment plan.