PIOZ MF 15MG TABLET 10'S
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PIOZ MF 15MG TABLET 10'S
PIOZ MF 15MG TABLET 10'S
PIOZ MF 15MG TABLET 10'S
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PIOZ MF 15MG TABLET 10'S

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PIOZ MF 15MG TABLET 10'S

By USV PRIVATE LIMITED

MRP

155.65

₹132.3

15 % OFF

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About PIOZ MF 15MG TABLET 10'S

  • PIOZ MF 15MG TABLET 10'S is a combination medication designed to help manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Pioglitazone and Metformin, each working through different mechanisms to improve glycemic control.
  • Pioglitazone belongs to a class of drugs called thiazolidinediones (TZDs). It enhances the body's sensitivity to insulin, allowing cells to utilize glucose more effectively. By improving insulin sensitivity in peripheral tissues like muscle and fat, Pioglitazone helps lower blood sugar levels. It also reduces glucose production in the liver.
  • Metformin is a biguanide that primarily works by decreasing glucose production in the liver and improving insulin sensitivity. It also slows down the absorption of glucose from the intestines. Metformin is often the first-line treatment for type 2 diabetes due to its effectiveness and relatively low risk of side effects.
  • This combination medication is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels. PIOZ MF 15MG TABLET helps to improve overall glycemic control, reducing the risk of long-term complications associated with diabetes, such as heart disease, kidney disease, and nerve damage. It is important to take this medication as directed by your healthcare provider and to maintain a healthy lifestyle, including a balanced diet and regular physical activity, to maximize its benefits.
  • Always consult with your doctor or pharmacist for personalized advice and to address any specific concerns or questions you may have regarding this medication. They can provide guidance on proper usage, potential side effects, and interactions with other medications you may be taking.

Uses of PIOZ MF 15MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering blood sugar levels
  • Improving insulin sensitivity
  • Managing insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)
  • Reducing the risk of heart disease (in some patients)
  • Management of obesity-related diabetes
  • Used in combination with other diabetes medications

How PIOZ MF 15MG TABLET 10'S Works

  • PIOZ MF 15MG TABLET 10'S is a combination medicine containing Pioglitazone and Metformin. It's designed to help control blood sugar levels in adults with type 2 diabetes. It works through multiple mechanisms to improve glycemic control.
  • Pioglitazone, a thiazolidinedione (TZD), increases the body's sensitivity to insulin. Insulin is a hormone that helps glucose (sugar) from the blood enter cells to be used for energy. In type 2 diabetes, cells become resistant to insulin, leading to high blood sugar levels. Pioglitazone works by activating a receptor called PPARγ (peroxisome proliferator-activated receptor gamma) inside cells. Activation of PPARγ leads to increased expression of genes involved in glucose and lipid metabolism. This results in improved insulin sensitivity in muscle, liver, and fat tissues. By making these tissues more responsive to insulin, pioglitazone helps glucose enter cells more effectively, lowering blood sugar levels. It also reduces glucose production in the liver.
  • Metformin, a biguanide, primarily works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues. It reduces hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Metformin also slows down the absorption of glucose from the intestines after a meal, further contributing to lower postprandial (after-meal) blood sugar spikes. Additionally, metformin increases insulin sensitivity by enhancing glucose uptake and utilization in peripheral tissues like muscle. This helps to utilize the available insulin more efficiently. Furthermore, Metformin has also been shown to have a positive impact on lipid profiles and can lead to modest weight loss in some individuals.
  • In combination, Pioglitazone and Metformin address different aspects of insulin resistance and glucose metabolism, providing a synergistic effect in lowering blood sugar levels. Pioglitazone improves insulin sensitivity in the periphery, while Metformin reduces glucose production in the liver and enhances peripheral insulin sensitivity. This dual mechanism helps to effectively control blood sugar levels in individuals with type 2 diabetes. This medicine is usually prescribed along with diet and exercise to achieve the best results.
  • It is important to note that PIOZ MF 15MG TABLET 10'S does not stimulate the pancreas to produce more insulin, therefore, it carries a lower risk of hypoglycemia (low blood sugar) compared to some other diabetes medications. However, it is essential to follow your doctor's instructions regarding dosage, diet, and exercise while taking this medicine to manage your blood sugar effectively and minimize potential side effects.

Side Effects of PIOZ MF 15MG TABLET 10'SArrow

The following side effects may occur while taking PIOZ MF 15MG TABLET 10'S: * Hypoglycemia (low blood sugar) - especially when used with other diabetes medications. * Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite. * Edema (swelling) - particularly in the legs and ankles. * Weight gain. * Upper respiratory tract infection. * Headache. * Muscle pain. * Visual disturbances. * Anemia. * Increased risk of bone fractures (in women). * Liver problems (rare). * Heart failure (rare). * Skin reactions like rash, itching or hives (rare).

Safety Advice for PIOZ MF 15MG TABLET 10'SArrow

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Allergies

Allergies

Do not consume PIOZ MF 15MG TABLET 10'S if you are allergic to it.

Dosage of PIOZ MF 15MG TABLET 10'SArrow

  • The dosage of PIOZ MF 15MG TABLET 10'S is highly individualized and should be determined by your physician based on your specific needs and response to treatment. Generally, the starting dose is one tablet once or twice daily, taken with meals to minimize gastrointestinal discomfort. Your doctor may gradually increase the dose based on your blood sugar levels, but the maximum recommended daily dose should not be exceeded. It's crucial to adhere to the prescribed dosage and timing to achieve optimal blood sugar control. Regular monitoring of blood glucose levels is essential to assess the effectiveness of the medication and to make necessary dosage adjustments. Consistency in taking PIOZ MF 15MG TABLET 10'S at the same time(s) each day helps maintain stable blood sugar levels. Do not abruptly stop taking this medication without consulting your doctor, as this may lead to a sudden increase in blood sugar. If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Never double the dose to catch up.
  • Remember, factors such as kidney function, liver function, and other medical conditions can influence the appropriate dosage. Always inform your doctor about all medications you are currently taking, including over-the-counter drugs and herbal supplements, as they may interact with PIOZ MF 15MG TABLET 10'S. Strict adherence to dietary recommendations and a regular exercise program are also vital components of managing diabetes effectively and may influence the required dosage of this medication. Your doctor will provide you with a comprehensive treatment plan that includes medication, diet, and exercise, tailored to your individual needs. Follow this plan closely to achieve the best possible outcome. Take 'PIOZ MF 15MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of PIOZ MF 15MG TABLET 10'S?Arrow

  • If you miss a dose of PIOZ MF 15MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store PIOZ MF 15MG TABLET 10'S?Arrow

  • Keep PIOZ MF 15MG TAB 1X10 away from the reach of children and pets.
  • Store PIOZ MF 15MG TAB 1X10 at room temperature.

Benefits of PIOZ MF 15MG TABLET 10'SArrow

  • PIOZ MF 15MG TABLET 10'S is a combination medication primarily used to manage type 2 diabetes mellitus. Its dual action helps control blood sugar levels effectively, offering several key benefits for individuals with this condition.
  • **Improved Glycemic Control:** The combination of pioglitazone and metformin works synergistically to lower blood glucose levels. Metformin reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues, while pioglitazone enhances insulin sensitivity in muscles and adipose tissue. This dual action leads to better overall glycemic control, reducing HbA1c levels and minimizing the risk of diabetes-related complications.
  • **Enhanced Insulin Sensitivity:** Pioglitazone, a thiazolidinedione (TZD), is a potent insulin sensitizer. It helps the body utilize insulin more effectively, addressing insulin resistance, a common underlying issue in type 2 diabetes. By improving insulin sensitivity, PIOZ MF 15MG TABLET 10'S helps cells absorb glucose from the bloodstream, lowering blood sugar levels.
  • **Reduced Hepatic Glucose Production:** Metformin, a biguanide, reduces the amount of glucose produced by the liver. This is particularly beneficial for individuals with type 2 diabetes who often experience excessive glucose production, especially overnight. By inhibiting hepatic glucose output, PIOZ MF 15MG TABLET 10'S helps prevent hyperglycemia.
  • **Cardiovascular Benefits:** Some studies suggest that pioglitazone may have cardiovascular benefits, such as improving lipid profiles (increasing HDL cholesterol and decreasing triglycerides) and reducing the risk of certain cardiovascular events. However, these benefits are still under investigation and should be considered as potential advantages rather than definitive outcomes. Metformin is also known to have some cardiovascular protective effects.
  • **Convenient Combination Therapy:** PIOZ MF 15MG TABLET 10'S offers the convenience of combining two effective antidiabetic medications into a single tablet. This simplifies the medication regimen for patients, potentially improving adherence and overall treatment outcomes. It reduces the pill burden, making it easier for individuals to manage their diabetes.
  • **Potential for Beta-Cell Preservation:** Pioglitazone may help preserve beta-cell function in the pancreas. Beta cells are responsible for producing insulin, and their decline is a hallmark of type 2 diabetes progression. By protecting beta cells, PIOZ MF 15MG TABLET 10'S may help prolong the body's ability to produce insulin, potentially delaying the need for insulin injections.
  • **Improved Lipid Profile:** Pioglitazone can improve lipid profiles by increasing high-density lipoprotein (HDL) cholesterol (often called "good" cholesterol) and decreasing triglycerides. This can contribute to a healthier cardiovascular system.
  • **May Reduce Risk of Macrovascular Complications:** Effective blood sugar control, improved lipid profiles, and potential cardiovascular benefits may collectively reduce the risk of macrovascular complications associated with diabetes, such as heart disease and stroke. By managing blood sugar and other risk factors, PIOZ MF 15MG TABLET 10'S contributes to long-term health and well-being.
  • **Overall Improved Quality of Life:** By effectively managing blood sugar levels and reducing the risk of diabetes-related complications, PIOZ MF 15MG TABLET 10'S can significantly improve the overall quality of life for individuals with type 2 diabetes. It allows them to lead more active and fulfilling lives with fewer health concerns.

How to use PIOZ MF 15MG TABLET 10'SArrow

  • PIOZ MF 15MG TABLET 10'S should be taken as directed by your physician. The dosage and frequency will depend on your specific condition and how your body responds to the medication. Typically, it is prescribed as part of a comprehensive diabetes management plan that includes diet and exercise.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it, as this can affect how the medication is released into your system. It is usually taken once or twice daily with meals to help reduce stomach upset and improve absorption. Try to take it at the same time(s) each day to maintain a consistent level of medication in your bloodstream.
  • It's crucial to adhere strictly to your doctor's instructions regarding dosage and timing. Do not increase or decrease the dose without consulting your doctor, even if you feel your symptoms are improving or worsening. Regular monitoring of your blood sugar levels is necessary while taking PIOZ MF 15MG TABLET 10'S to assess its effectiveness and adjust the treatment plan if needed.
  • Inform your doctor about all other medications, supplements, or herbal products you are currently taking, as they may interact with PIOZ MF 15MG TABLET 10'S. Pay close attention to any side effects you experience and report them to your doctor promptly. Common side effects may include nausea, diarrhea, or headaches. If you experience severe or persistent side effects, seek medical attention immediately.
  • Continue taking PIOZ MF 15MG TABLET 10'S for the duration prescribed by your doctor, even if you feel well. Do not stop taking it abruptly without consulting your doctor, as this may lead to a sudden increase in your blood sugar levels. Lifestyle modifications, such as maintaining a healthy diet and engaging in regular physical activity, are essential for managing diabetes effectively while taking this medication.

Quick Tips for PIOZ MF 15MG TABLET 10'SArrow

  • Take PIOZ MF 15MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once or twice daily with meals to help manage blood sugar levels effectively. Consistency is key for optimal results.
  • PIOZ MF 15MG TABLET 10'S combines pioglitazone and metformin, each addressing insulin resistance and glucose production differently. Understand that this medicine works best when combined with a healthy diet and regular exercise. Focus on incorporating balanced meals and physical activity into your daily routine for enhanced blood sugar control. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Be aware of potential side effects. Common side effects may include nausea, diarrhea, headache, or upper respiratory tract infection. More serious side effects can include symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, sudden weight gain), liver problems (such as persistent nausea/vomiting, stomach/abdominal pain, dark urine, yellowing eyes/skin), or lactic acidosis. Report any persistent or severe side effects to your doctor immediately.
  • Regular monitoring is crucial. While taking PIOZ MF 15MG TABLET 10'S, your doctor will likely monitor your blood sugar levels, kidney function, and liver function regularly. Attend all scheduled appointments and undergo the recommended blood tests. These tests help ensure the medication is working effectively and to detect any potential problems early. Also, inform your doctor about any other medications, supplements, or herbal remedies you are taking to avoid potential drug interactions.
  • Understand the signs of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). Symptoms of hypoglycemia may include shakiness, sweating, confusion, dizziness, or rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, frequent urination, blurred vision, or fatigue. Knowing these signs and how to manage them can prevent complications. Always carry a source of fast-acting glucose (such as glucose tablets or fruit juice) in case of hypoglycemia.

FAQs

What is the use of PIOZ MF 15MG TABLET 10'S?

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PIOZ MF 15MG TABLET 10'S is used to treat type 2 diabetes mellitus when diet and exercise alone are not sufficient to control blood sugar levels.

How does PIOZ MF 15MG TABLET 10'S work?

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PIOZ MF 15MG TABLET 10'S is a combination of two medicines: Pioglitazone and Metformin. Pioglitazone works by increasing insulin sensitivity, while Metformin reduces the amount of glucose produced by the liver and improves the body's response to insulin.

What are the common side effects of PIOZ MF 15MG TABLET 10'S?

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Common side effects of PIOZ MF 15MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is PIOZ MF 15MG TABLET 10'S safe for kidneys?

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PIOZ MF 15MG TABLET 10'S should be used with caution in patients with kidney disease. Dose adjustments may be necessary. Please consult your doctor.

Is PIOZ MF 15MG TABLET 10'S safe during pregnancy?

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The safety of PIOZ MF 15MG TABLET 10'S during pregnancy has not been established. Consult your doctor before using it during pregnancy.

How to store PIOZ MF 15MG TABLET 10'S?

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Store PIOZ MF 15MG TABLET 10'S at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

What happens if I miss a dose of PIOZ MF 15MG TABLET 10'S?

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If you miss a dose of PIOZ MF 15MG TABLET 10'S, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose.

Is it safe to drink alcohol with PIOZ MF 15MG TABLET 10'S?

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Alcohol consumption should be avoided while taking PIOZ MF 15MG TABLET 10'S as it may lower blood sugar levels and increase the risk of side effects.

Does PIOZ MF 15MG TABLET 10'S cause weight gain?

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PIOZ MF 15MG TABLET 10'S may cause weight gain in some patients. Talk to your doctor if you experience significant weight gain.

How long does it take for PIOZ MF 15MG TABLET 10'S to start working?

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It may take a few weeks for PIOZ MF 15MG TABLET 10'S to have a noticeable effect on blood sugar levels.

Can PIOZ MF 15MG TABLET 10'S be taken with other diabetes medications?

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PIOZ MF 15MG TABLET 10'S can be taken with other diabetes medications, but only under the supervision of a doctor.

Can PIOZ MF 15MG TABLET 10'S cause hypoglycemia?

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PIOZ MF 15MG TABLET 10'S does not usually cause hypoglycemia on its own, but it can cause hypoglycemia if taken with other diabetes medications, such as insulin or sulfonylureas.

Is PIOZ MF 15MG TABLET 10'S harmful to the heart?

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PIOZ MF 15MG TABLET 10'S may increase the risk of heart failure in some patients. Patients with heart disease should use it with caution.

What are other brands of Metformin?

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Some other brands of Metformin include Glucophage, Fortamet, and Glumetza.

Can PIOZ MF 15MG TABLET 10'S cause blurred vision?

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PIOZ MF 15MG TABLET 10'S can cause blurred vision in some patients. Inform your doctor if you experience any changes in vision.

References

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FDA - Actos (pioglitazone) Label - prescribing information including clinical studies, adverse reactions and drug interactions

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DrugBank - Pioglitazone - Comprehensive information on pioglitazone, including its mechanism of action, pharmacokinetics, and therapeutic uses.

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NCBI - Thiazolidinediones and heart failure: a meta-analysis - Meta-analysis examining the cardiovascular effects of thiazolidinediones, including pioglitazone.

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EMA - Actos (pioglitazone) - European Medicines Agency information on pioglitazone, including its safety profile and regulatory status.

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ScienceDirect - Pioglitazone - Overview of pioglitazone, including its pharmacology and clinical applications.

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MedlinePlus - Pioglitazone - Patient-oriented information on pioglitazone, including its uses, side effects, and precautions. Note: While patient-oriented, it often links to more technical information.

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