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PIPZO 2.25 GM INJECTION

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PIPZO 2.25 GM INJECTION

By ALKEM LABORATORIES LIMITED

MRP

214.52

₹182.34

15 % OFF

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Product DetailsArrow

About PIPZO 2.25 GM INJECTION

  • PIPZO 2.25 GM Injection is a powerful antibiotic combination containing Piperacillin and Tazobactam. Piperacillin belongs to the penicillin group of antibiotics and works by preventing bacteria from forming their protective cell walls. Tazobactam is a beta-lactamase inhibitor, which means it prevents bacteria from inactivating Piperacillin. This combination makes PIPZO 2.25 GM Injection effective against a wide range of bacterial infections.
  • This injectable medication is typically administered intravenously or intramuscularly by a healthcare professional. It is prescribed for treating serious infections such as pneumonia, intra-abdominal infections, skin and soft tissue infections, and gynecological infections. The precise dosage and duration of treatment will be determined by the severity and type of infection, as well as the patient's overall health condition.
  • PIPZO 2.25 GM Injection offers a broad spectrum of activity against both gram-positive and gram-negative bacteria, including many resistant strains. It's crucial to complete the full course of treatment as prescribed by your doctor, even if you start feeling better before the medication is finished. This helps ensure that the infection is completely eradicated and prevents the development of antibiotic resistance. As with all medications, PIPZO 2.25 GM Injection may cause side effects, so discuss any concerns with your healthcare provider.

Uses of PIPZO 2.25 GM INJECTION

  • Pneumonia (Lung Infection)
  • Skin and soft tissue infections
  • Intra-abdominal infections
  • Urinary tract infections
  • Septicemia (Bloodstream infection)
  • Gynecological infections
  • Bone and joint infections
  • Pneumonia acquired during hospitalization
  • Febrile neutropenia (Fever in patients with low white blood cell count)
  • Bacterial Meningitis

How PIPZO 2.25 GM INJECTION Works

  • PIPZO 2.25 GM INJECTION is a powerful antibiotic combination medication containing Piperacillin and Tazobactam. It's designed to combat a wide range of bacterial infections throughout the body. To understand how it works, it's essential to consider the individual roles of its active ingredients: Piperacillin and Tazobactam.
  • Piperacillin belongs to a class of antibiotics known as penicillin. It functions by interfering with the bacteria's ability to build and maintain their cell walls. Bacteria require peptidoglycans, which are complex sugar-protein molecules, to form their cell walls. Piperacillin inhibits the enzymes responsible for synthesizing peptidoglycans. By blocking this process, Piperacillin weakens the bacterial cell wall, eventually leading to its rupture and the death of the bacteria. This targeted approach makes Piperacillin effective against many types of bacteria.
  • However, some bacteria develop resistance to penicillin-based antibiotics like Piperacillin. They produce an enzyme called beta-lactamase, which can break down the structure of the antibiotic, rendering it ineffective. This is where Tazobactam comes into play.
  • Tazobactam is a beta-lactamase inhibitor. It works by binding to and inactivating the beta-lactamase enzymes produced by resistant bacteria. By neutralizing these enzymes, Tazobactam prevents the breakdown of Piperacillin, allowing it to reach its target and effectively destroy the bacteria. In essence, Tazobactam protects Piperacillin from being deactivated, ensuring that the antibiotic can perform its function.
  • The combination of Piperacillin and Tazobactam creates a synergistic effect. Piperacillin directly attacks the bacterial cell wall, while Tazobactam protects Piperacillin from being destroyed by bacterial resistance mechanisms. This combination broadens the spectrum of bacteria that the injection can effectively treat. It's effective against bacteria that are resistant to Piperacillin alone.
  • In summary, PIPZO 2.25 GM INJECTION works through a dual mechanism: Piperacillin disrupts bacterial cell wall synthesis, leading to bacterial cell death, and Tazobactam inhibits beta-lactamase enzymes, preventing the breakdown of Piperacillin and enhancing its effectiveness against resistant bacteria. This combination ensures a potent antibiotic effect against a wide range of susceptible bacteria.
  • The injection is administered intravenously or intramuscularly, allowing the medication to quickly enter the bloodstream and reach the site of infection. Dosage and duration of treatment are determined by a healthcare professional, depending on the severity and location of the infection, as well as the patient's overall health condition.

Side Effects of PIPZO 2.25 GM INJECTIONArrow

Like all medicines, PIPZO 2.25 GM INJECTION can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Diarrhea * Nausea * Vomiting * Rash * Itching * Injection site reactions (redness, swelling, pain) * Abnormal liver function tests **Uncommon side effects (may affect up to 1 in 100 people):** * Oral thrush (fungal infection in the mouth) * Headache * Dizziness * Indigestion * Abdominal pain * Constipation * Anxiety * Insomnia * Low blood potassium * Muscle spasms * Hives * Fever * Changes in blood cell counts (e.g., anemia, thrombocytopenia, leukopenia) * Elevated creatinine levels in blood **Rare side effects (may affect up to 1 in 1,000 people):** * Severe allergic reactions (anaphylaxis) - symptoms may include difficulty breathing, wheezing, swelling of the face, lips, tongue, or throat, and skin rash. * Stevens-Johnson syndrome (a severe skin reaction with blistering and peeling of the skin) * Toxic epidermal necrolysis (a more severe form of Stevens-Johnson syndrome) * Clostridium difficile-associated diarrhea (severe diarrhea caused by a specific bacteria) * Seizures * Kidney problems **Very rare side effects (may affect up to 1 in 10,000 people):** * Drug-induced liver injury **Not known (frequency cannot be estimated from the available data):** * Serious skin reactions * Hallucinations * Delirium This is not an exhaustive list. If you experience any unusual symptoms while taking PIPZO 2.25 GM INJECTION, consult your doctor or pharmacist immediately.

Safety Advice for PIPZO 2.25 GM INJECTIONArrow

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Allergies

Unsafe

Do not use if you are allergic to PIPZO 2.25 GM INJECTION.

Dosage of PIPZO 2.25 GM INJECTIONArrow

  • The recommended dosage of PIPZO 2.25 GM INJECTION varies depending on the severity and type of infection being treated, as well as the patient's age, weight, and kidney function. It is crucial to adhere to the dosage prescribed by your doctor. Typical adult dosages range from 2.25 grams to 4.5 grams administered intravenously every 6 to 8 hours.
  • For patients with impaired kidney function, dosage adjustments are necessary to prevent drug accumulation and potential toxicity. Your doctor will carefully assess your kidney function and adjust the PIPZO 2.25 GM INJECTION dosage accordingly. In children, the dosage is based on their weight and the severity of the infection. The typical dosage range is between 100 to 200 mg per kg of body weight per day, divided into doses administered every 6 to 8 hours.
  • PIPZO 2.25 GM INJECTION is administered intravenously by a healthcare professional. The duration of treatment depends on the infection type and patient response. It's vital to complete the entire course of treatment as prescribed by your doctor, even if you start feeling better. Stopping the medication prematurely may lead to the infection recurring or the development of antibiotic resistance. During treatment, your doctor may monitor your kidney function and electrolytes to ensure the medication is safe and effective.
  • Take 'PIPZO 2.25 GM INJECTION' only as per the prescription by your physician only

What if I miss my dose of PIPZO 2.25 GM INJECTION?Arrow

  • If you miss a dose of PIPZO 2.25 GM INJECTION, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store PIPZO 2.25 GM INJECTION?Arrow

  • Keep PIPZO 2.25GM INJ away from the reach of children and pets.
  • Store PIPZO 2.25GM INJ at room temperature.

Benefits of PIPZO 2.25 GM INJECTIONArrow

  • PIPZO 2.25 GM INJECTION is a powerful antibiotic medication combining piperacillin and tazobactam to combat a wide range of bacterial infections. Its broad-spectrum activity makes it effective against various Gram-positive and Gram-negative bacteria, as well as anaerobic bacteria, ensuring comprehensive coverage in complex infections. This combination therapy enhances piperacillin's effectiveness by preventing its breakdown by beta-lactamase enzymes produced by resistant bacteria.
  • One of the primary benefits of PIPZO 2.25 GM INJECTION is its efficacy in treating severe infections, including pneumonia, bloodstream infections (bacteremia), intra-abdominal infections, and skin and soft tissue infections. It is often used in hospital settings to manage infections in critically ill patients. The injection is particularly useful when the causative bacteria are unknown or suspected to be resistant to other antibiotics.
  • PIPZO 2.25 GM INJECTION is also beneficial in treating complicated urinary tract infections (cUTIs) and pyelonephritis. Its potent antibacterial action helps eradicate the bacteria from the urinary tract, alleviating symptoms and preventing further complications. Furthermore, it can be used prophylactically in surgical procedures to prevent post-operative infections, especially in high-risk surgeries.
  • In addition to its therapeutic uses, PIPZO 2.25 GM INJECTION plays a vital role in managing infections in immunocompromised patients, such as those undergoing chemotherapy or with weakened immune systems. These patients are more susceptible to opportunistic infections, and PIPZO provides a strong defense against a wide array of pathogens. Its ability to target multiple types of bacteria simultaneously is crucial in these vulnerable populations.
  • The rapid onset of action of PIPZO 2.25 GM INJECTION is another significant advantage, allowing for quick control of the infection and improvement in patient outcomes. Administered intravenously, it reaches the bloodstream directly, ensuring maximum bioavailability and prompt delivery to the site of infection. This makes it a preferred choice in situations where timely intervention is critical.
  • PIPZO 2.25 GM INJECTION helps in reducing the duration of hospital stays by effectively treating infections and preventing complications. Its use can lead to faster recovery times and a decreased need for prolonged hospitalization, thereby reducing healthcare costs and improving patient satisfaction.
  • PIPZO 2.25 GM INJECTION’s reliable and consistent performance makes it a trusted option for healthcare professionals in combating severe bacterial infections. Its widespread availability and well-established safety profile further contribute to its utility in clinical practice. The combination of piperacillin and tazobactam offers a synergistic effect, enhancing the overall antibacterial activity and improving the chances of successful treatment outcomes.

How to use PIPZO 2.25 GM INJECTIONArrow

  • PIPZO 2.25 GM INJECTION is administered intravenously by a healthcare professional. It should not be self-administered. The dosage and duration of treatment depend on the severity and type of infection, as well as the patient's kidney function and overall condition. Your doctor will determine the correct dose for you.
  • Before administration, PIPZO 2.25 GM INJECTION must be reconstituted with a compatible solution, such as sterile water for injection or sodium chloride injection. The resulting solution should be clear and free from particulate matter. The reconstituted solution is then further diluted in an appropriate intravenous solution.
  • The injection is usually given slowly over a period of 30 minutes to several hours, depending on the prescribed dose. During the infusion, you will be monitored for any signs of allergic reactions or other adverse effects. It's crucial to inform your doctor immediately if you experience any unusual symptoms, such as rash, itching, swelling, or difficulty breathing.
  • To ensure the effectiveness of PIPZO 2.25 GM INJECTION, it is important to complete the full course of treatment, even if you start feeling better after a few days. Stopping the medication prematurely may allow the infection to persist and increase the risk of antibiotic resistance.
  • Inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with PIPZO 2.25 GM INJECTION. Also, inform your doctor if you have any allergies, kidney problems, or other medical conditions. If you experience any side effects, such as diarrhea, nausea, or vomiting, consult your doctor for advice.
  • The injection should be stored as per the manufacturer's instructions. Typically, it needs to be kept in a cool, dry place away from direct sunlight. Discard any unused portion of the reconstituted solution properly, following healthcare guidelines.
  • If you miss a dose of PIPZO 2.25 GM INJECTION, contact your healthcare provider immediately to determine when you should receive the next dose. Do not double the dose to catch up. Regular and timely administration is crucial for effective treatment. Make sure you attend all follow-up appointments with your doctor to monitor your progress and address any concerns.

Quick Tips for PIPZO 2.25 GM INJECTIONArrow

  • Complete the Full Course: Even if you start feeling better, finish the entire course of PIPZO 2.25 GM INJECTION as prescribed by your doctor. Stopping early can lead to the infection returning and becoming harder to treat.
  • Report Any Side Effects: Immediately inform your doctor if you experience any severe side effects, such as allergic reactions (rash, itching, swelling), persistent diarrhea, or signs of kidney problems (changes in urination).
  • Maintain Hydration: Drink plenty of fluids while you are on PIPZO 2.25 GM INJECTION to help prevent dehydration and support kidney function. Water is ideal; avoid excessive sugary drinks.
  • Inform Your Doctor About Other Medications: Before starting PIPZO 2.25 GM INJECTION, tell your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. This helps prevent potential drug interactions.
  • Administered by Healthcare Professional: PIPZO 2.25 GM INJECTION must be administered by a trained healthcare professional. Do not attempt to self-administer this medication. Ensure the injection site is properly cleaned before administration.
  • Monitor for Injection Site Reactions: After the injection, keep an eye on the injection site for any signs of irritation, pain, swelling, or redness. Report any unusual reactions to your healthcare provider promptly.
  • Discuss Contraception: PIPZO can interfere with some oral contraceptives. Discuss with your doctor about using additional non-hormonal methods of contraception while on PIPZO injection.

Food Interactions with PIPZO 2.25 GM INJECTIONArrow

  • PIPZO 2.25 GM INJECTION does not have any known interactions with food. It can be administered without regard to meals.

FAQs

What is PIPZO 2.25 GM Injection?Arrow

PIPZO 2.25 GM Injection is an antibiotic medicine used to treat various bacterial infections. It contains Piperacillin and Tazobactam.

What types of infections does PIPZO 2.25 GM Injection treat?Arrow

PIPZO 2.25 GM Injection is used to treat a variety of bacterial infections, including pneumonia, urinary tract infections, abdominal infections, skin and soft tissue infections, and blood infections.

How is PIPZO 2.25 GM Injection administered?Arrow

PIPZO 2.25 GM Injection is usually administered by a healthcare professional as an injection into a vein.

What are the common side effects of PIPZO 2.25 GM Injection?Arrow

Common side effects of PIPZO 2.25 GM Injection include nausea, vomiting, diarrhea, pain or swelling at the injection site, and headache.

Are there any serious side effects of PIPZO 2.25 GM Injection?Arrow

In rare cases, PIPZO 2.25 GM Injection may cause serious allergic reactions, bleeding problems, or kidney problems. Seek immediate medical attention if you experience any of these side effects.

Can PIPZO 2.25 GM Injection interact with other medications?Arrow

PIPZO 2.25 GM Injection can interact with certain medications, such as anticoagulants and some antibiotics. Inform your doctor about all the medications you are taking.

How should PIPZO 2.25 GM Injection be stored?Arrow

PIPZO 2.25 GM Injection should be stored at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

Is it safe to use PIPZO 2.25 GM Injection during pregnancy?Arrow

PIPZO 2.25 GM Injection should be used during pregnancy only when clearly needed and prescribed by a doctor.

Is it safe to use PIPZO 2.25 GM Injection during breastfeeding?Arrow

It is not known whether PIPZO 2.25 GM Injection is excreted in breast milk. Consult your doctor before breastfeeding.

Can PIPZO 2.25 GM Injection cause antibiotic resistance?Arrow

Like any antibiotic, overuse of PIPZO 2.25 GM Injection can lead to antibiotic resistance. Use it only when prescribed by your doctor and for the prescribed dosage and duration.

What happens if I miss a dose of PIPZO 2.25 GM Injection?Arrow

If you miss a dose of PIPZO 2.25 GM Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Can I drink alcohol with PIPZO 2.25 GM Injection?Arrow

It is not recommended to drink alcohol with PIPZO 2.25 GM Injection as it may increase the risk of side effects.

Does PIPZO 2.25 GM Injection treat viral infections?Arrow

No, PIPZO 2.25 GM Injection is an antibiotic and is only effective for treating bacterial infections, not viral infections.

Can PIPZO 2.25 GM Injection cause allergic reactions?Arrow

Yes, some people may be allergic to PIPZO 2.25 GM Injection. Seek immediate medical attention if you experience symptoms of an allergic reaction such as rash, itching, swelling, or difficulty breathing.

Are there other brands of Piperacillin and Tazobactam available?Arrow

Yes, Piperacillin and Tazobactam are marketed by various manufacturers under different brand names. Ask your pharmacist or doctor which brand is most suitable for you.

References

Book Icon

PIPZO (piperacillin and tazobactam) injection, for intravenous use. Full prescribing information, including details on composition, clinical studies, and safety information. (FDA Label)

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DrugBank entry for Piperacillin: Provides chemical structure, pharmacology, interactions, and other technical details.

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DrugBank entry for Tazobactam: Provides chemical structure, pharmacology, interactions, and other technical details.

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Book Icon

Pharmacokinetics and Pharmacodynamics of Piperacillin/Tazobactam: Key Information for Optimizing Antipseudomonal Therapy. Research paper on pharmacokinetics and pharmacodynamics.

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European Medicines Agency (EMA) Assessment Report on Piperacillin/Tazobactam: Provides a detailed scientific evaluation of the medicine.

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Population Pharmacokinetics of Piperacillin and Tazobactam in Critically Ill Patients: Implications for Dosage Optimization. Antimicrobial Agents and Chemotherapy. Research article.

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Piperacillin/Tazobactam. StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. A review of piperacillin/tazobactam, covering mechanism of action, indications, and adverse effects.

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UpToDate Drug Information: Piperacillin/tazobactam: Provides clinical information, including dosing, administration, and adverse effects.

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Marketer / Manufacturer Details

ALKEM LABORATORIES LIMITED

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India

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PIPZO 2.25GM INJ - 10478 - Medkart Pharmacy | Generic Medicines Online - Best Online Pharmacy App

PIPZO 2.25 GM INJECTION

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₹182.34

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