PIRFENEX TABLET 15'S
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PIRFENEX TABLET 15'SPIRFENEX TABLET 15'SPIRFENEX TABLET 15'S
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PIRFENEX TABLET 15'S

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PIRFENEX TABLET 15'S

By CIPLA PHARMACEUTICAL COMPANY LIMITED

MRP

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420.05

₹357.04

15 % OFF

₹23.8 Only /

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Product DetailsArrow

About PIRFENEX TABLET 15'S

  • PIRFENEX TABLET 15'S contains pirfenidone, a transforming growth factor-beta (TGF-β) inhibitor, and is specifically indicated for the treatment of idiopathic pulmonary fibrosis (IPF) in adults. IPF is a chronic and progressive lung disease characterized by scarring (fibrosis) of the lung tissue, leading to shortness of breath and reduced lung function. PIRFENEX TABLET 15'S helps to reduce the progression of IPF by interfering with the signaling pathways involved in fibrosis.
  • Before starting PIRFENEX TABLET 15'S, it's crucial to inform your doctor if you have any pre-existing liver or kidney conditions, or if you are currently taking fluvoxamine, a medication used to treat depression and obsessive-compulsive disorder. This medication is contraindicated in individuals with severe hepatic or renal impairment, or those with a known allergy to pirfenidone or any of the tablet's other ingredients. It is also advised to avoid consuming grapefruit juice while taking this medicine, as it can potentially interact with pirfenidone and increase its concentration in the body.
  • During treatment with PIRFENEX TABLET 15'S, some individuals may experience gastrointestinal side effects such as nausea, vomiting, diarrhea, or indigestion. Additionally, the medication can sometimes lead to elevated liver enzyme levels. If you notice any unusual symptoms or persistent discomfort, it is important to promptly consult your doctor. Be vigilant for signs of liver problems such as dark urine, jaundice (yellowing of the skin or eyes), or unusual bruising or bleeding, and report them to your healthcare provider immediately. PIRFENEX TABLET 15'S is generally not recommended for use in children and adolescents under the age of 18 years.
  • While taking PIRFENEX TABLET 15'S, it's advisable to avoid smoking, as smoking can potentially reduce the medication's effectiveness. Furthermore, it's important to minimize exposure to sunlight, including sunlamps, as pirfenidone can increase your skin's sensitivity to the sun. When outdoors, wear protective clothing, use sunscreen with a high SPF, and consider wearing a hat to shield your face and head.

Uses of PIRFENEX TABLET 15'S

  • Idiopathic pulmonary fibrosis: This refers to a chronic and progressive lung disease characterized by the scarring of lung tissue, leading to difficulty in breathing.

How PIRFENEX TABLET 15'S Works

  • PIRFENEX TABLET 15'S works by reducing fibrosis and inflammation in the lungs, slowing down the progression of idiopathic pulmonary fibrosis (IPF).
  • PIRFENEX TABLET 15'S exerts its therapeutic effects in idiopathic pulmonary fibrosis (IPF) through multiple mechanisms. It is believed to inhibit the synthesis and release of various pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1β), and transforming growth factor-beta (TGF-beta). By reducing the levels of these cytokines, PIRFENEX TABLET 15'S helps decrease inflammation and fibrosis in the lungs. It also inhibits the production of fibroblast growth factors (FGFs) and platelet-derived growth factors (PDGFs), which are involved in the excessive formation of scar tissue. Moreover, PIRFENEX TABLET 15'S has antioxidant properties that protect lung cells from oxidative stress, further contributing to its anti-fibrotic effects. These combined actions help slow down the progression of IPF, improve lung function, and alleviate symptoms in affected individuals.

Side Effects of PIRFENEX TABLET 15'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

  • Severe allergic reactions (swelling of face, lips, or tongue, wheezing, feeling faint)
  • Liver problems (yellowing of skin or eyes, dark urine, bruising, or bleeding)
  • Nausea, vomiting
  • Loss of appetite, tiredness
  • Diarrhea, indigestion
  • Headache, dizziness
  • Skin reactions after exposure to sunlight
  • Infections
  • Weight loss
  • Difficulty sleeping
  • Changes in taste
  • Cough
  • Stomach pain, constipation, feeling bloated, heartburn
  • Itchy, dry skin
  • Muscle pain, joint pain
  • Chest pain, shortness of breath

Safety Advice for PIRFENEX TABLET 15'SArrow

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Pregnancy

UNSAFE

PIRFENEX TABLET 15'S may cause harm to the unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this medicine.

Dosage of PIRFENEX TABLET 15'SArrow

  • Always adhere to your doctor's prescribed dosage and duration when taking PIRFENEX TABLET 15'S. For optimal results and to minimize potential side effects, swallow the tablets whole with a glass of water after a meal. It is crucial to maintain a consistent daily schedule by taking the tablet at the same time each day.
  • Avoid crushing or chewing the tablets, as this can affect the way the medication is absorbed into your system. The integrity of the tablet's coating is important for its proper release and effectiveness.
  • It is also important to avoid consuming grapefruit juice while taking PIRFENEX TABLET 15'S. Grapefruit juice can interfere with the medication's metabolism and potentially increase the risk of side effects. Follow your doctor's instructions carefully and consult them if you have any concerns.
  • If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store PIRFENEX TABLET 15'S?Arrow

  • Keep PIRFENEX TAB 1X15 away from the reach of children and pets.
  • Store PIRFENEX TAB 1X15 at room temperature.

Benefits of PIRFENEX TABLET 15'SArrow

  • PIRFENEX TABLET 15'S contains pirfenidone, which functions by targeting the underlying mechanisms of fibrosis. Fibrosis involves the excessive buildup of scar tissue in the lungs, leading to stiffness and impaired function. PIRFENEX TABLET 15'S works to diminish the creation and buildup of extracellular matrix (ECM) proteins, the primary components of this scar tissue. By reducing ECM protein production, PIRFENEX TABLET 15'S helps slow down the fibrotic process.
  • The medication's impact extends to various factors involved in fibrosis, including transforming growth factor-beta (TGF-β) and tumor necrosis factor-alpha (TNF-α), both of which play critical roles in inflammation and scar tissue formation. By modulating these factors, PIRFENEX TABLET 15'S helps to reduce inflammation and further inhibit the progression of fibrosis.
  • Ultimately, PIRFENEX TABLET 15'S aims to slow the advancement of the disease, maintain lung function for a longer period, and improve overall respiratory health. While it's not a cure, it can significantly improve the quality of life for individuals with idiopathic pulmonary fibrosis.

How to use PIRFENEX TABLET 15'SArrow

  • Take PIRFENEX TABLET 15'S exactly as prescribed by your doctor. It is crucial to follow your doctor's instructions regarding the dosage and duration of treatment to achieve the best possible results and minimize potential side effects.
  • Swallow the tablets whole with a glass of water. Avoid crushing or chewing the tablets, as this can affect how the medication is absorbed into your system. It's best to maintain a consistent routine by taking the tablet at the same time each day.
  • To minimize potential side effects, it's recommended to take PIRFENEX TABLET 15'S after a meal. Food can help to reduce gastrointestinal discomfort and improve tolerance of the medication.
  • Avoid consuming grapefruit or grapefruit juice while taking PIRFENEX TABLET 15'S. Grapefruit can interact with the medication and alter its concentration in your body, potentially leading to adverse effects.
  • If you have any questions or concerns about how to take PIRFENEX TABLET 15'S, or if you experience any unusual side effects, consult with your doctor or pharmacist for further guidance.

FAQs

How does PIRFENEX TABLET 15'S work?Arrow

PIRFENEX TABLET 15'S works by reducing inflammation and fibrosis in the lungs. It inhibits the production of certain molecules that cause scarring and stiffening of the lung tissue.

How long should I take PIRFENEX TABLET 15'S?Arrow

PIRFENEX TABLET 15'S is a long-term medication that is taken indefinitely for treating IPF. Anyways, the duration of treatment may vary depending on the individual patient's response to the medication and other factors.

Who should not take PIRFENEX TABLET 15'S?Arrow

PIRFENEX TABLET 15'S is not recommended for pregnant or breastfeeding women and those with severe liver or kidney disease.

What dosage of PIRFENEX TABLET 15'S should I take?Arrow

It is important to note that the dosage of PIRFENEX TABLET 15'S may vary based on factors such as the patient's age, weight, renal function, and other medications they may be taking. Dosage adjustments may be necessary based on side effects or changes in the patient's condition. As with all medications, it is important to follow the dosage instructions provided by your healthcare provider and to consult with them if you have any questions or concerns.

What should I do if I miss a dose of PIRFENEX TABLET 15'S?Arrow

If you miss a dose of PIRFENEX TABLET 15'S, take it as soon as you remember. Skip the missed dose and continue with your regular dosing schedule.

What tests should I take before starting the PIRFENEX TABLET 15'S?Arrow

Your doctor will recommend you to take a liver function test before starting the cycles with PIRFENEX TABLET 15'S to monitor the functioning level.

NULL interaction of PIRFENEX TABLET 15'S with other drungsArrow

There is NULL interaction of PIRFENEX TABLET 15'S with other drugs.

Advice related to PIRFENEX TABLET 15'SArrow

If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Abnormalities, such as dark or brown urine, bruises, bleeding than usual, or jaundice, must be notified immediately to your doctor. Avoid smoking while taking Pirfenex 200mg tablet because it may reduce the effectiveness of the medicine. Avoid exposure to sunlight, including sunlamps. Use sunscreen daily and cover your head, legs, and arms to reduce exposure to sunlight. Before starting the treatment, it is recommended to perform a liver function test.

What is Pirfenidone?Arrow

PIRFENIDONE is molecule/combination used for making PIRFENEX TABLET 15'S.

For which disease PIRFENEX TABLET 15'S is prescribed?Arrow

PIRFENEX TABLET 15'S is prescribed for Pulmonology and Cardiology diseases.

References

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Roche Products Limited, Electronic medicines compendium (emc)

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Genentech USA, Inc, US Food and Drug Administration

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Pirfenex Tablets; Cipla Ltd; Ciplamed

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Marketer / Manufacturer Details

CIPLA PHARMACEUTICAL COMPANY LIMITED

Country of Origin -

India

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PIRFENEX TABLET 15'S

PIRFENEX TABLET 15'S

MRP

₹

420.05

₹357.04

15 % OFF

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