POLYBACT H EYE OINTMENT 5 GM

How POLYBACT H EYE OINTMENT 5 GM Works

• POLYBACT H Eye Ointment is a combination medication designed to treat bacterial infections of the eye, often accompanied by inflammation. It achieves its therapeutic effect through the synergistic action of its active ingredients: Polymyxin B, Bacitracin, and Hydrocortisone.
• Polymyxin B and Bacitracin are both polypeptide antibiotics, meaning they disrupt bacterial cell function through different mechanisms. Polymyxin B works by binding to and disrupting the structure of the bacterial cell membrane. This disruption increases the permeability of the membrane, leading to leakage of essential cellular components and ultimately, bacterial cell death. It is particularly effective against Gram-negative bacteria, a common culprit in eye infections.
• Bacitracin, on the other hand, inhibits bacterial cell wall synthesis. Specifically, it interferes with the dephosphorylation of a lipid carrier molecule that is essential for transporting peptidoglycans (the building blocks of the cell wall) across the cell membrane. By preventing the formation of a functional cell wall, Bacitracin weakens the bacteria and leads to its lysis. Bacitracin demonstrates a broad spectrum of activity against Gram-positive bacteria.
• The combination of Polymyxin B and Bacitracin provides a broad-spectrum antibacterial effect, targeting a wide range of bacteria commonly responsible for eye infections. This dual antibiotic action minimizes the risk of bacterial resistance and enhances the overall efficacy of the ointment.
• Hydrocortisone is a corticosteroid, a type of steroid medication that reduces inflammation. In the context of eye infections, inflammation can manifest as redness, swelling, itching, and pain. Hydrocortisone works by suppressing the inflammatory response at the cellular level. It inhibits the production of inflammatory mediators, such as prostaglandins and leukotrienes, thereby alleviating the symptoms associated with the infection.
• By reducing inflammation, Hydrocortisone not only provides symptomatic relief but also helps to improve the penetration of the antibiotics into the infected tissues. This is because inflammation can constrict blood vessels and limit drug delivery to the affected area. The combination of antibiotics to eradicate the infection and a corticosteroid to control the associated inflammation makes POLYBACT H Eye Ointment a comprehensive treatment for bacterial eye infections.

Like all medicines, POLYBACT H EYE OINTMENT 5 GM can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Eye irritation (burning, stinging, itching, redness) * Blurred vision * Allergic reactions (skin rash around the eyes) **Uncommon side effects (may affect up to 1 in 100 people):** * Swelling of the eyelids * Increased tear production * Sensitivity to light **Rare side effects (may affect up to 1 in 1,000 people):** * Cataracts (long term use) * Glaucoma (long term use) * Secondary eye infections **Very rare side effects (may affect up to 1 in 10,000 people):** * Systemic allergic reactions **Frequency not known:** * Temporary burning or stinging sensation after application * Local allergic reactions

• If you miss a dose of POLYBACT H EYE OINTMENT 5 GM, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

• Keep POLYBACT H EYE OINTMENT 5GM away from the reach of children and pets.
• Store POLYBACT H EYE OINTMENT 5GM at room temperature.

• Always wash your hands thoroughly with soap and water before applying POLYBACT H EYE OINTMENT 5 GM. This helps prevent the introduction of additional bacteria into the eye and minimizes the risk of further infection or contamination.
• Apply a thin layer of POLYBACT H EYE OINTMENT 5 GM inside the lower eyelid, gently pulling it down to create a small pocket. Avoid touching the tip of the tube to your eye or any other surface to prevent contamination of the ointment.
• Use POLYBACT H EYE OINTMENT 5 GM exactly as prescribed by your doctor. Complete the full course of treatment, even if your symptoms improve, to ensure the infection is completely eradicated and to prevent antibiotic resistance.
• If you wear contact lenses, remove them before applying POLYBACT H EYE OINTMENT 5 GM and do not reinsert them until at least 15 minutes after application, or as directed by your doctor. Contact lenses can trap bacteria and interfere with the ointment's effectiveness.
• Store POLYBACT H EYE OINTMENT 5 GM at room temperature, away from direct sunlight and heat. Keep the tube tightly closed when not in use and do not use it if the seal is broken or the ointment has changed color or consistency. Discard any remaining ointment after the course of treatment is completed.

• POLYBACT H EYE OINTMENT 5 GM is for external use only and is unlikely to interact with food. However, to avoid any potential interactions, it is generally recommended to maintain a consistent diet and inform your doctor about any existing dietary restrictions or supplements you are taking.