PRAMIPEX ER 0.75
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PRAMIPEX ER 0.75
PRAMIPEX ER 0.75MG TABLET
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PRAMIPEX ER 0.75MG TABLET 10'S

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PRAMIPEX ER 0.75MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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181

₹153.85

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About PRAMIPEX ER 0.75MG TABLET 10'S

  • PRAMIPEX ER 0.75MG TABLET 10'S is prescribed for managing Parkinson's disease and restless leg syndrome (RLS). RLS is characterized by an irresistible urge to move the legs, often accompanied by uncomfortable sensations.
  • This medication helps alleviate excessive shaking and slow down body movements associated with Parkinson's. It works by affecting certain chemical messengers in the brain to improve motor control and reduce the symptoms of RLS.
  • For optimal results, take PRAMIPEX ER 0.75MG TABLET 10'S with food, ideally at the same time each day. Consistent timing helps maintain a stable level of the medication in your system. Follow your doctor's prescribed dosage and duration of treatment meticulously. If you miss a dose, take it as soon as you remember. However, it is crucial to avoid skipping doses and to complete the full course of treatment, even if you start feeling better.
  • Do not discontinue this medication abruptly without consulting your doctor, as this could lead to withdrawal symptoms or a worsening of your condition.
  • Common side effects associated with PRAMIPEX ER 0.75MG TABLET 10'S include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema (swelling in the extremities). Dizziness and sleepiness are also frequently reported. Therefore, exercise caution while driving or operating machinery until you understand how the medication affects you.
  • It is important to inform your doctor if you experience any unusual mood changes, an abnormally heightened sex drive, an uncontrollable urge to gamble, or compulsive spending habits, as these could indicate more serious side effects. Regular monitoring and open communication with your healthcare provider are essential while taking this medication.

Uses of PRAMIPEX ER 0.75MG TABLET 10'S

  • Parkinson's disease: This medication helps manage symptoms of Parkinson's disease, such as tremors, rigidity, and slow movement. It is prescribed to improve motor control and overall quality of life for individuals with this condition.
  • Restless leg syndrome: This medication is useful in treating Restless Leg Syndrome (RLS), which causes uncomfortable sensations in the legs and an uncontrollable urge to move them. It helps reduce the urge to move your legs, allowing for better sleep and improved daily function.

How PRAMIPEX ER 0.75MG TABLET 10'S Works

  • PRAMIPEX ER 0.75MG TABLET 10'S works by acting like dopamine, a naturally occurring chemical in your brain. Dopamine is a crucial neurotransmitter, meaning it transmits signals between nerve cells (neurons). It plays a vital role in controlling movement, coordination, and other important functions.
  • In conditions like Parkinson's disease, the nerve cells that produce dopamine are gradually lost. This dopamine deficiency leads to the symptoms of Parkinson's, such as tremors, stiffness, slow movement, and postural instability. By mimicking dopamine, PRAMIPEX ER 0.75MG TABLET 10'S helps to compensate for this deficiency.
  • The medication binds to dopamine receptors in the brain, stimulating them and restoring some of the dopamine's effects. This, in turn, helps to improve motor control, reduce stiffness, and alleviate other symptoms associated with dopamine deficiency. The 'ER' in PRAMIPEX ER 0.75MG TABLET 10'S stands for extended-release, meaning that the medication is released slowly into the body over a longer period, providing a more consistent effect throughout the day.

Side Effects of PRAMIPEX ER 0.75MG TABLET 10'S
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Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

  • Dizziness
  • Sleepiness
  • Nausea
  • Dryness in mouth
  • Fatigue
  • Hallucination
  • Constipation
  • Peripheral edema
  • Muscle spasm

Safety Advice for PRAMIPEX ER 0.75MG TABLET 10'S
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Liver Function

Safe if prescribed

PRAMIPEX ER 0.75MG TABLET 10'S is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of PRAMIPEX ER 0.75MG TABLET 10'S may not be needed in these patients. Please consult your doctor.

Dosage of PRAMIPEX ER 0.75MG TABLET 10'S
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  • Dosage for children: The use of PRAMIPEX ER 0.75MG TABLET 10'S in children is generally not recommended. The dosage and safety in this population should be determined by a pediatric specialist.
  • Dosage for adults: The initial recommended dose for Parkinson's disease is usually 0.125 mg three times daily. The dosage is gradually increased based on individual response and tolerability. The maximum recommended daily dose is typically 4.5 mg. For restless legs syndrome, the initial dose is usually 0.125 mg once daily, taken 2-3 hours before bedtime. The dosage may be adjusted based on the therapeutic response but should not exceed 0.5 mg per day.

How to store PRAMIPEX ER 0.75MG TABLET 10'S?
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  • Keep PRAMIPEX ER 0.75MG TAB 1X10 away from the reach of children and pets.
  • Store PRAMIPEX ER 0.75MG TAB 1X10 at room temperature.

Benefits of PRAMIPEX ER 0.75MG TABLET 10'S
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  • PRAMIPEX ER 0.75MG TABLET 10'S offers a sustained-release formulation, providing a steady release of pramipexole over an extended period. This helps in maintaining consistent drug levels in the body, reducing fluctuations and improving symptom control for individuals managing Parkinson's disease or Restless Legs Syndrome (RLS).
  • By delivering pramipexole in a controlled manner, PRAMIPEX ER 0.75MG TABLET 10'S can minimize the frequency of dosing. This convenience is particularly beneficial for patients who may find it challenging to adhere to multiple daily doses, leading to better treatment compliance and overall improved outcomes.
  • PRAMIPEX ER 0.75MG TABLET 10'S helps in alleviating motor symptoms associated with Parkinson's disease, such as tremors, rigidity, and slowness of movement. It can also significantly reduce the urge to move the legs and associated discomfort experienced by individuals with Restless Legs Syndrome, promoting restful sleep and enhancing the quality of life.
  • The extended-release formulation of PRAMIPEX ER 0.75MG TABLET 10'S may lead to a reduction in the severity and occurrence of certain side effects commonly associated with immediate-release pramipexole. This can improve tolerability and allow patients to continue treatment without significant disruptions. Consulting with a healthcare professional is crucial to address any concerns or side effects.
  • PRAMIPEX ER 0.75MG TABLET 10'S can be used as monotherapy in the early stages of Parkinson's disease or as an adjunct therapy in later stages when used with levodopa. This versatility allows healthcare providers to tailor treatment regimens according to individual patient needs and disease progression, maximizing therapeutic benefits.

How to use PRAMIPEX ER 0.75MG TABLET 10'S
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  • Always adhere to your doctor's instructions regarding the dosage and duration of this medication. It is crucial to follow their recommendations precisely for optimal results and to minimize potential side effects. Swallow the tablet whole with a full glass of water. Avoid chewing, crushing, or breaking the tablet, as this could affect how the medication is released and absorbed into your system. Taking PRAMIPEX ER 0.75MG TABLET 10'S with food is generally recommended. This can help to reduce the likelihood of stomach upset or nausea that some individuals may experience. Consistency is key; try to take the medication at the same time each day to maintain a steady level of the drug in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • If you have any questions or concerns about how to take PRAMIPEX ER 0.75MG TABLET 10'S, don't hesitate to ask your doctor or pharmacist for clarification. They can provide personalized guidance based on your specific medical condition and any other medications you may be taking.

Quick Tips for PRAMIPEX ER 0.75MG TABLET 10'S
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  • PRAMIPEX ER 0.75MG TABLET 10'S has been prescribed to alleviate symptoms of Parkinson's disease and/or restless leg syndrome. It works by mimicking the effects of dopamine in the brain, helping to control movement and reduce the urge to move your legs.
  • This medication can be taken either with or without food. If you experience nausea, taking it with food may help to reduce this side effect. Always take the tablet at the same time each day to maintain a consistent level of medication in your body.
  • If you are taking PRAMIPEX ER 0.75MG TABLET 10'S for restless leg syndrome, it is best to take it 2 to 3 hours before you go to bed. This allows the medication to take effect and reduce your symptoms while you are trying to sleep.
  • Be cautious when performing activities that require alertness, such as driving or operating machinery, until you know how PRAMIPEX ER 0.75MG TABLET 10'S affects you. It can cause drowsiness or dizziness in some people, which could be dangerous.
  • When you first start taking PRAMIPEX ER 0.75MG TABLET 10'S, you may experience a sudden drop in blood pressure when you change positions, especially when standing up from sitting or lying down. To minimize this risk, rise slowly and carefully.
  • It's important to be aware of potential side effects. Contact your doctor if you experience hallucinations, unusual thoughts, or any other changes in your behavior while taking this medication. Promptly reporting these changes can help manage them effectively.
  • PRAMIPEX ER 0.75MG TABLET 10'S may also lead to compulsive behaviors that are difficult to control, such as binge eating, gambling, excessive spending, or increased sexual urges. If you notice any of these behaviors developing, inform your doctor immediately.
  • Do not abruptly stop taking PRAMIPEX ER 0.75MG TABLET 10'S without consulting your doctor. Suddenly stopping the medication can cause withdrawal symptoms or a worsening of your condition. Your doctor will advise you on how to gradually reduce the dosage if necessary.
  • Adhere strictly to your doctor's dosage instructions. Do not increase or decrease the amount of medication you take without first consulting your healthcare provider. Consistent and correct usage will help ensure the best possible outcome.
  • Store PRAMIPEX ER 0.75MG TABLET 10'S at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Proper storage helps maintain the medication's effectiveness and safety.

FAQs

Does PRAMIPEX ER 0.75MG TABLET 10'S cause weight gain?

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A common side effect of PRAMIPEX ER 0.75MG TABLET 10'S is decrease in body weight which may be due to decrease in appetite. Uncommonly, it can also cause increase in weight. However, if you have concerns regarding your weight talk to your doctor or a nutritionist.

Does PRAMIPEX ER 0.75MG TABLET 10'S make you sleepy?

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Yes, PRAMIPEX ER 0.75MG TABLET 10'S may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery and inform your doctor.

How does PRAMIPEX ER 0.75MG TABLET 10'S work for restless legs?

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Restless leg syndrome (RLS) is a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down. PRAMIPEX ER 0.75MG TABLET 10'S belongs to dopamine (neurotransmitter) agonist class of medicines. It acts by stimulating the dopamine receptors which is needed in the brain to control movement. Hence, it is used to improve RLS.

Is PRAMIPEX ER 0.75MG TABLET 10'S a muscle relaxant?

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No, PRAMIPEX ER 0.75MG TABLET 10'S is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.

Can I stop taking PRAMIPEX ER 0.75MG TABLET 10'S if my symptoms of Parkinson’s disease have improved?

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You should not stop PRAMIPEX ER 0.75MG TABLET 10'S without talking to your doctor. Sudden discontinuation of PRAMIPEX ER 0.75MG TABLET 10'S may cause neuroleptic malignant syndrome. The symptoms of malignant syndrome include loss of muscle movement, rigid muscles, fever, unstable blood pressure, increased heart rate, confusion, and depressed level of consciousness.

How should PRAMIPEX ER 0.75MG TABLET 10'S be taken?

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You should take PRAMIPEX ER 0.75MG TABLET 10'S as directed by your doctor. The doctor will decide your dose depending on the condition you are being treated for. Preferably it should be taken 2-3 hours before bedtime. Swallow the tablets whole with water. It can be taken with or without food, but taking it with food may help reduce the chances of nausea.

What are the serious side effects of PRAMIPEX ER 0.75MG TABLET 10'S?

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The serious side effects of PRAMIPEX ER 0.75MG TABLET 10'S include hallucinations (seeing things or hearing voices that do not exist), confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, abnormal body movements, and motions that you cannot control. It may also cause changes in the way you sit or stand that you cannot control, such as your neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand or walk. Additionally, it may cause dark, red or cola-colored urine, muscle tenderness, muscle stiffness or aching and muscle weakness. Call your doctor immediately if you experience any of these.

What are impulse control disorders caused by PRAMIPEX ER 0.75MG TABLET 10'S?

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PRAMIPEX ER 0.75MG TABLET 10'S may cause impulse control disorders in which you may have cravings or urge to behave in an unusual manner, which normally you would not do. PRAMIPEX ER 0.75MG TABLET 10'S may also make it hard for you to resist the impulse to carry certain activities which can harm you or others, like addictive gambling, excessive eating or spending money. Along with that, it may cause an abnormally high sex drive or preoccupation with an increase in sexual thoughts or feelings.

References

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Pramipexole dihydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim International GmbH; 2010. (online) Available from:

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Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. (online) Available from:

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Pramipexole. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 . (online) Available from:

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Central Drugs Standard Control Organisation (CDSCO). (online) Available from:

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Pramipexole dihydrochloride [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021. (online) Available from:

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PRAMIPEX ER 0.75MG TABLET 10'S

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