PREGABA D 75/30MG CAPSULE 10'S

How PREGABA D 75/30MG CAPSULE 10'S Works

• PREGABA D 75/30MG CAPSULE is a combination medicine used to treat neuropathic pain. This medication contains Pregabalin and Duloxetine as its active ingredients, which work through different mechanisms to alleviate pain associated with nerve damage. Pregabalin, an analogue of gamma-aminobutyric acid (GABA), primarily functions by binding to the α2δ subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin modulates the influx of calcium at nerve terminals, leading to a reduction in the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. These neurotransmitters are involved in the transmission of pain signals in the brain. Consequently, by reducing their release, Pregabalin helps in diminishing the perception of pain.
• Duloxetine, on the other hand, is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). It works by blocking the reuptake of serotonin and norepinephrine in the synaptic cleft, which are neurotransmitters that play a crucial role in regulating mood and pain pathways in the brain and spinal cord. By preventing their reuptake, Duloxetine increases the concentration of these neurotransmitters in the synaptic space, enhancing their activity. Increased levels of serotonin and norepinephrine can modulate pain signals, elevate mood, and improve overall well-being. The combined action of Pregabalin and Duloxetine provides a synergistic effect in managing neuropathic pain, addressing both the neuronal excitability and the neurotransmitter imbalances associated with chronic pain conditions.
• In essence, PREGABA D 75/30MG CAPSULE works on multiple fronts: Pregabalin targets the overexcited nerve signals by reducing the release of excitatory neurotransmitters, thereby calming the nerves and decreasing the intensity of pain signals. Duloxetine helps balance the chemical signals in the brain, improving mood and reducing the sensation of pain. This dual mechanism not only alleviates pain but also addresses the emotional and psychological aspects often associated with chronic neuropathic pain. The combination of these two medications offers a comprehensive approach to managing neuropathic pain, allowing patients to experience significant relief and improved quality of life. Always consult with a healthcare professional for proper diagnosis and treatment plans.

Common side effects of PREGABA D 75/30MG CAPSULE may include: * Dizziness * Sleepiness * Headache * Dry mouth * Blurred vision * Weight gain * Difficulty concentrating * Swelling of extremities (arms and legs) * Increased appetite * Constipation Less common but potentially serious side effects include: * Allergic reactions (rash, itching, swelling) * Changes in mood or behavior (depression, anxiety, suicidal thoughts) * Muscle pain or weakness * Numbness or tingling in the hands or feet * Vision changes * Loss of coordination * Memory problems * Sexual dysfunction * Gastrointestinal issues (nausea, vomiting, diarrhea) * Liver problems (yellowing of skin or eyes) * Heart problems (irregular heartbeat, chest pain) This is not an exhaustive list. If you experience any unusual or bothersome symptoms while taking PREGABA D 75/30MG CAPSULE, consult your doctor immediately.

• If you miss a dose of PREGABA D 75/30MG CAPSULE 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGABA D 75/30MG CAP 1X10 away from the reach of children and pets.
• Store PREGABA D 75/30MG CAP 1X10 at room temperature.

• **Take PREGABA D 75/30MG CAPSULE as prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not alter the dose without consulting them, even if you feel better or worse.
• **Be consistent with timing:** Take PREGABA D 75/30MG CAPSULE at the same time each day to maintain a consistent level of medication in your body. This helps ensure the medicine works effectively.
• **Manage potential side effects:** Be aware of potential side effects such as dizziness, drowsiness, or nausea. If these occur, avoid activities requiring alertness, like driving, until you know how the medication affects you. Report persistent or severe side effects to your doctor.
• **Inform your doctor of other medications:** Tell your doctor about all other medications, supplements, and herbal products you are taking. PREGABA D 75/30MG CAPSULE can interact with other drugs, potentially affecting their efficacy or increasing the risk of side effects.
• **Avoid alcohol:** Alcohol can enhance the sedative effects of PREGABA D 75/30MG CAPSULE, increasing the risk of dizziness, drowsiness, and impaired coordination. It's best to avoid alcohol while taking this medication.
• **Store properly:** Store PREGABA D 75/30MG CAPSULE in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets.
• **Do not stop abruptly:** Do not stop taking PREGABA D 75/30MG CAPSULE suddenly without consulting your doctor. Abruptly stopping the medication can lead to withdrawal symptoms.
• **Discuss pre-existing conditions:** Inform your doctor about any pre-existing medical conditions you have, such as kidney problems, heart problems, or a history of substance abuse. These conditions may affect how PREGABA D 75/30MG CAPSULE works or increase the risk of side effects.
• **Maintain a healthy lifestyle:** Complement your medication with a healthy lifestyle. This includes regular exercise, a balanced diet, and adequate sleep. A healthy lifestyle can improve your overall well-being and help manage your condition more effectively.