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PREGABID D 50/20MG TABLET 10'S

Name: PREGABID D 50/20MG TABLET 10'S
Brand: INTAS PHARMACEUTICALS LIMITED
Price: 145.83 INR
Availability: InStoreOnly

PREGABID D 50/20MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

MRP

₹

171.56

₹145.83

15 % OFF

₹14.58 Only /

Tablet

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Composition

DULOXETINE 20 MG SUSTAINED RELEASE+PREGABALIN 50 MG

Product Details

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About PREGABID D 50/20MG TABLET 10'S

Pregabid D 50/20 mg Tablet is a combination medicine formulated to relieve neuropathic (nerve) pain and improve overall well-being. It combines pregabalin 50 mg with duloxetine 20 mg (sustained release), two ingredients that tackle pain through distinct but complementary mechanisms, making it a common choice for chronic nerve pain that also affects mood.
Pregabalin, an anticonvulsant, works by modulating calcium channels in nerve cells, which reduces the release of the neurotransmitters that send pain signals to the brain and so lessens the perception of pain. It is particularly effective for nerve-related pain conditions, calming over-active nerve impulses.
Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) that acts as both an antidepressant and a pain reliever. It works by increasing the levels of serotonin and norepinephrine in the brain, neurotransmitters that play a crucial role in mood regulation and in the body's own pain-dampening pathways. By enhancing their availability, duloxetine helps relieve both pain and the associated low mood that often accompanies persistent pain. Here it is provided in a sustained-release form for steadier effect.
This combination is often prescribed for conditions such as diabetic neuropathy (nerve damage due to diabetes), fibromyalgia (widespread musculoskeletal pain), and postherpetic neuralgia (pain after shingles). Pregabid D is designed to manage chronic pain effectively and improve quality of life, and it should always be used under medical supervision.
Patients should consult their healthcare provider to decide whether Pregabid D 50/20 mg is right for them, discussing any existing medical conditions — including kidney, liver, or heart problems and any history of mood disorders — as well as current medicines and potential allergies to ensure safe, effective treatment. The dose and duration are set by the doctor based on individual needs. Because both ingredients act on the nervous system, do not stop the medicine abruptly, avoid alcohol, take care when driving until you know how it affects you, and report any marked mood changes promptly.
Generic alternative: a generic medicine has the same active composition as the branded product — for Pregabid D 50/20mg Tablet 10's that is Pregabalin 50 Mg+duloxetine 20 MG Sustained Release. On Medkart you can compare generic options by composition and see the price difference before you buy; the molecule, strength and dosage form match. Always consult your doctor or pharmacist before switching.

Uses of PREGABID D 50/20MG TABLET 10'S

Neuropathic pain treatment
Fibromyalgia management
Diabetic neuropathy relief
Post-herpetic neuralgia management
Spinal cord injury-related pain treatment
Anxiety disorders management
Adjunctive treatment for partial seizures (epilepsy)

How PREGABID D 50/20MG TABLET 10'S Works

PREGABID D 50/20MG TABLET 10'S is a combination medicine containing Pregabalin and Duloxetine. It is primarily used to manage neuropathic pain, a type of pain caused by nerve damage. Understanding how each component works is crucial to appreciating the overall effectiveness of this medication.
Pregabalin, one of the active ingredients, is an anticonvulsant and analgesic. It works by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin modulates the influx of calcium at nerve terminals. This action reduces the release of several neurotransmitters, including glutamate, noradrenaline, and substance P, all of which play a role in transmitting pain signals. Essentially, Pregabalin dampens the overactivity of nerves that cause neuropathic pain, thereby alleviating the sensation of pain.
Duloxetine, the second active ingredient, is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). It functions by inhibiting the reuptake of serotonin and norepinephrine in the brain and spinal cord. Serotonin and norepinephrine are neurotransmitters that help regulate mood and also play a role in pain modulation. By blocking their reuptake, Duloxetine increases the concentration of these neurotransmitters in the synaptic cleft (the space between nerve cells). This enhanced neurotransmission helps to improve mood and reduce the perception of pain signals. In essence, Duloxetine boosts the body's natural pain-fighting mechanisms.
The synergistic action of Pregabalin and Duloxetine provides comprehensive pain relief. Pregabalin targets the source of the nerve pain by reducing the excitability of the nerves, while Duloxetine enhances the descending inhibitory pathways in the central nervous system to further reduce pain signals. Together, they address both the cause and the perception of neuropathic pain.
In simpler terms, think of neuropathic pain as a faulty electrical wire sending out erratic signals. Pregabalin works like a circuit breaker, calming down the overactive nerve signals. Duloxetine acts like a volume control, turning down the overall intensity of the pain signals being received by the brain. This combined approach helps to restore a more normal pain signaling process, providing significant relief to individuals suffering from neuropathic pain.

Side Effects of PREGABID D 50/20MG TABLET 10'S

Common side effects of Pregabid D 50/20mg Tablet may include: Dizziness, Sleepiness, Tiredness, Uncoordinated body movements, Blurred vision, Dryness in mouth, Constipation, Difficulty in urination, Weight gain, Peripheral edema (swelling of the extremities). Less common but potentially serious side effects include: Mood changes, Depression, Suicidal thoughts, Muscle pain or weakness, Severe skin reactions (rash, itching, swelling), Allergic reactions (difficulty breathing, swelling of the face or throat). This is not an exhaustive list, and other side effects may occur. Consult your doctor if you experience any unusual or bothersome symptoms.

Safety Advice for PREGABID D 50/20MG TABLET 10'S

Allergies

Do not use PREGABID D 50/20MG TABLET 10'S if you are allergic to it or any of its ingredients.

Dosage of PREGABID D 50/20MG TABLET 10'S

The recommended dosage of PREGABID D 50/20MG TABLET 10'S varies significantly based on individual patient needs, the severity of their condition, and their response to treatment. It is crucial to adhere strictly to your physician's prescribed dosage and schedule. Self-adjusting the dose can lead to ineffective treatment or increased risk of side effects. Take 'PREGABID D 50/20MG TABLET 10'S' only as per the prescription by your physician only
Typically, PREGABID D 50/20MG TABLET 10'S is initiated at a lower dose, which may be gradually increased by your doctor over time to achieve optimal pain relief or symptom control. The starting dose often ranges from one tablet once or twice daily. The maximum daily dose should not exceed what your doctor has prescribed.
The tablet should be swallowed whole with a glass of water, with or without food. Consistency in timing is important for maintaining stable blood levels of the medication. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.
Patients with kidney problems may require dosage adjustments. Your doctor will carefully evaluate your kidney function to determine the appropriate dose for you. It's essential to inform your doctor about any existing kidney conditions or changes in kidney function during treatment. Elderly patients might also need lower doses due to age-related changes in metabolism and kidney function. Regular monitoring by your healthcare provider is essential to ensure the medication's safety and effectiveness. Long-term use should be discussed with your physician to evaluate continued need and potential risks.

What if I miss my dose of PREGABID D 50/20MG TABLET 10'S?

If you miss a dose of PREGABID D 50/20MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store PREGABID D 50/20MG TABLET 10'S?

Keep PREGABID D 50/20MG TAB 1X10 away from the reach of children and pets.
Store PREGABID D 50/20MG TAB 1X10 at room temperature.

Benefits of PREGABID D 50/20MG TABLET 10'S

PREGABID D 50/20MG TABLET 10'S offers a dual-action approach to managing neuropathic pain and associated symptoms, providing significant relief and improved quality of life. The combination of pregabalin and duloxetine addresses pain through different mechanisms, enhancing the overall effectiveness of the treatment.
Pregabalin, an active ingredient, works by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the release of excitatory neurotransmitters, such as glutamate, noradrenaline, and substance P, which are involved in transmitting pain signals. By modulating these neurotransmitters, pregabalin helps to calm overactive nerves and reduce the intensity of pain sensations. This mechanism is particularly effective in alleviating neuropathic pain arising from nerve damage or dysfunction.
Duloxetine, the other key component, is a selective serotonin and norepinephrine reuptake inhibitor (SNRI). It increases the levels of serotonin and norepinephrine in the brain, which are neurotransmitters that play a crucial role in regulating mood and pain pathways. By enhancing the activity of these neurotransmitters, duloxetine not only helps in reducing pain but also improves mood, alleviates symptoms of depression, and reduces anxiety often associated with chronic pain conditions. This makes PREGABID D 50/20MG TABLET 10'S particularly useful for patients experiencing both pain and mood disturbances.
The synergistic action of pregabalin and duloxetine means that PREGABID D 50/20MG TABLET 10'S can provide more comprehensive pain relief compared to either medication used alone. This combination can effectively manage various types of neuropathic pain, including diabetic neuropathy (nerve pain caused by diabetes), postherpetic neuralgia (nerve pain after shingles), fibromyalgia, and pain associated with spinal cord injuries. It's also beneficial in treating conditions like chronic musculoskeletal pain and certain types of cancer pain where nerve involvement is significant.
Beyond pain relief, PREGABID D 50/20MG TABLET 10'S can improve sleep quality, which is often disrupted by chronic pain. By reducing pain and anxiety, the medication helps patients achieve more restful and restorative sleep. This, in turn, can lead to improved daytime functioning, reduced fatigue, and enhanced overall well-being.
Furthermore, the dual-action formula can help reduce the need for other pain medications, potentially minimizing the risk of side effects associated with long-term use of multiple drugs. This is especially important for patients who may be sensitive to the adverse effects of certain pain relievers or who have other medical conditions that limit their treatment options.
In summary, PREGABID D 50/20MG TABLET 10'S offers a multifaceted approach to pain management, addressing both the physical and emotional aspects of chronic pain. Its benefits include significant pain relief, improved mood, reduced anxiety, better sleep quality, and a potential reduction in the need for other pain medications. This makes it a valuable option for patients seeking comprehensive and effective treatment for neuropathic pain and associated conditions.

How to use PREGABID D 50/20MG TABLET 10'S

PREGABID D 50/20MG TABLET 10'S is intended for oral administration. Always take this medicine exactly as your doctor has told you. The usual dosage is determined by your doctor based on your individual needs and medical condition. It's crucial to follow their instructions precisely.
Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this could affect how the medicine is released and absorbed in your body.
PREGABID D 50/20MG TABLET 10'S can be taken with or without food. However, taking it at the same time each day will help you remember to take it regularly and maintain a consistent level of medication in your system. Consistency is key to effectively managing your condition.
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
It's important to continue taking PREGABID D 50/20MG TABLET 10'S for the full duration of treatment prescribed by your doctor, even if you feel better. Stopping the medication prematurely may lead to a worsening of your condition or the return of symptoms.
If you have any concerns about taking PREGABID D 50/20MG TABLET 10'S, or experience any side effects, consult your doctor or pharmacist immediately. They can provide you with the appropriate guidance and support. Regular follow-up appointments with your doctor are also essential to monitor your progress and adjust your treatment plan as needed.

Quick Tips for PREGABID D 50/20MG TABLET 10'S

Take PREGABID D 50/20MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your physician, as this could lead to withdrawal symptoms or a worsening of your condition. This medication is typically used to manage neuropathic pain and anxiety disorders, so consistency is key for optimal results.
Be aware of potential side effects. Common side effects of PREGABID D can include dizziness, drowsiness, dry mouth, blurred vision, and weight gain. If these side effects are persistent or bothersome, inform your doctor. Avoid activities requiring alertness, such as driving or operating machinery, until you know how this medication affects you.
Inform your doctor about all other medications, supplements, and herbal products you are currently taking. PREGABID D can interact with other substances, potentially leading to adverse effects or reduced efficacy. It's crucial to provide a complete medical history to ensure the safe and effective use of this medication. Special attention should be given to other medications that cause drowsiness, such as antihistamines or sleeping pills.
Store PREGABID D 50/20MG TABLET 10'S properly. Keep it in a cool, dry place away from direct sunlight and moisture. Ensure it is out of reach of children and pets. Proper storage helps maintain the medication's effectiveness and prevents accidental ingestion.
If you miss a dose of PREGABID D, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have any concerns about missed doses, consult your doctor or pharmacist for guidance.

Food Interactions with PREGABID D 50/20MG TABLET 10'S

PREGABID D 50/20MG TABLET 10'S can be taken with or without food. However, it is important to maintain a consistent dietary pattern. If you experience any stomach upset, taking it with food may help.
Avoid alcohol consumption while taking this medication as it can increase drowsiness and other side effects.

FAQs

What is the use of Pregabid D 50/20mg Tablet?

Pregabid D 50/20mg Tablet is primarily used to treat neuropathic pain (pain due to nerve damage) and anxiety disorders.

How does Pregabid D 50/20mg Tablet work?

Pregabid D 50/20mg Tablet works by reducing pain signals in the brain and decreasing the over-activity of nerve cells.

What are the common side effects of Pregabid D 50/20mg Tablet?

Common side effects of Pregabid D 50/20mg Tablet include dizziness, drowsiness, blurred vision, weight gain, and dry mouth.

Is Pregabid D 50/20mg Tablet addictive?

Pregabid D 50/20mg Tablet has the potential to be addictive, so it should only be taken as prescribed by a doctor.

How to store Pregabid D 50/20mg Tablet?

Store Pregabid D 50/20mg Tablet at room temperature, away from direct sunlight and moisture.

Can Pregabid D 50/20mg Tablet be taken with or without food?

Pregabid D 50/20mg Tablet can be taken with or without food, but it is better to take it at the same time each day.

What happens if I miss a dose of Pregabid D 50/20mg Tablet?

If you miss a dose of Pregabid D 50/20mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose.

Is Pregabid D 50/20mg Tablet safe during pregnancy?

Pregabid D 50/20mg Tablet is not safe during pregnancy and should only be taken if recommended by a doctor.

Is Pregabid D 50/20mg Tablet safe during breastfeeding?

Pregabid D 50/20mg Tablet is not safe during breastfeeding and should only be taken if recommended by a doctor.

Which medications should not be taken with Pregabid D 50/20mg Tablet?

Pregabid D 50/20mg Tablet should not be taken with opioid pain relievers, benzodiazepines, and alcohol.

What are the symptoms of an overdose of Pregabid D 50/20mg Tablet?

Symptoms of an overdose of Pregabid D 50/20mg Tablet include drowsiness, confusion, dizziness, and difficulty breathing.

Does Pregabid D 50/20mg Tablet affect the ability to drive?

Pregabid D 50/20mg Tablet may affect the ability to drive as it can cause dizziness and drowsiness.

What should I tell my doctor before taking Pregabid D 50/20mg Tablet?

Before taking Pregabid D 50/20mg Tablet, you should tell your doctor about all your medical conditions, allergies, and medications.

Can Pregabid D 50/20mg Tablet cause weight gain?

Yes, Pregabid D 50/20mg Tablet can cause weight gain in some people.

Is Pregabid D 50/20mg Tablet available under other brand names?

Yes, Pregabid D 50/20mg Tablet may be available under different brand names from different manufacturers.

What is Pregabid D 50/20MG Tablet 10's used for?

Pregabid D 50/20MG Tablet 10's is used for major depressive disorder; generalised anxiety disorder; diabetic peripheral neuropathic pain; fibromyalgia; chronic musculoskeletal pain; and neuropathic pain; adjunct treatment of partial-onset seizures; generalised anxiety disorder and fibromyalgia in some settings. Pregabid D 50/20MG Tablet 10's contains Duloxetine 20 MG Sustained Release + Pregabalin 50 MG. Always use Pregabid D 50/20MG Tablet 10's as advised by your doctor.

What is the composition of Pregabid D 50/20MG Tablet 10's?

Pregabid D 50/20MG Tablet 10's contains Duloxetine 20 MG Sustained Release + Pregabalin 50 MG. It is a SNRI antidepressant; and gabapentinoid; alpha-2-delta calcium channel ligand.

What are the side effects of Pregabid D 50/20MG Tablet 10's?

Commonly reported side effects of Pregabid D 50/20MG Tablet 10's include nausea, dry mouth, drowsiness, constipation, reduced appetite, sweating, sexual dysfunction; and dizziness, drowsiness, weight gain, dry mouth, blurred vision, swelling of hands and feet, difficulty concentrating. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.

What is the price of Pregabid D 50/20MG Tablet 10's?

Pregabid D 50/20MG Tablet 10's is listed at Rs. 145.83 on Medkart. Prices can change — check the product page for the current price and pack size.

What precautions should be taken with Pregabid D 50/20MG Tablet 10's?

Increased suicidal thinking in children, adolescents and young adults — monitor closely early and after dose changes; and Impairs driving and machine operation. Tell your doctor about all other medicines you take before starting Pregabid D 50/20MG Tablet 10's.

What is the correct dosage of Pregabid D 50/20MG Tablet 10's?

The dose of Pregabid D 50/20MG Tablet 10's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.

Is there a generic substitute for Pregabid D 50/20MG Tablet 10's?

A generic medicine is one with the same active composition as the branded product — for Pregabid D 50/20MG Tablet 10's that is Duloxetine 20 MG Sustained Release + Pregabalin 50 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Pregabid D 50/20MG Tablet 10's.

How does Pregabid D 50/20MG Tablet 10's work?

Pregabid D 50/20MG Tablet 10's contains Duloxetine 20 MG Sustained Release + Pregabalin 50 MG, a SNRI antidepressant; and gabapentinoid; alpha-2-delta calcium channel ligand. It is used for major depressive disorder.

Is Pregabid D 50/20MG Tablet 10's a prescription medicine?

Yes. Pregabid D 50/20MG Tablet 10's requires a valid doctor's prescription.

Who is the manufacturer of Pregabid D 50/20MG Tablet 10's?

Pregabid D 50/20MG Tablet 10's is manufactured by Intas Pharmaceuticals Limited.

What is the dosage form of Pregabid D 50/20MG Tablet 10's?

Pregabid D 50/20MG Tablet 10's is supplied as a tablet and is taken by the oral route.

What are the benefits of Pregabid D 50/20MG Tablet 10's?

Pregabid D 50/20MG Tablet 10's contains Duloxetine 20 MG Sustained Release + Pregabalin 50 MG. It is used for major depressive disorder; generalised anxiety disorder; diabetic peripheral neuropathic pain; fibromyalgia; chronic musculoskeletal pain; and neuropathic pain; adjunct treatment of partial-onset seizures; generalised anxiety disorder and fibromyalgia in some settings. The benefit you get depends on the condition your doctor prescribed Pregabid D 50/20MG Tablet 10's for.

Is Pregabid D 50/20MG Tablet 10's safe to take daily?

Whether Pregabid D 50/20MG Tablet 10's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Pregabid D 50/20MG Tablet 10's on your own.

When should Pregabid D 50/20MG Tablet 10's be taken — morning or night?

The timing of Pregabid D 50/20MG Tablet 10's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.

Can I take Pregabid D 50/20MG Tablet 10's without a doctor's consultation?

No. Pregabid D 50/20MG Tablet 10's is a prescription medicine and should only be taken on a doctor's advice.

Can Pregabid D 50/20MG Tablet 10's be taken during pregnancy or breastfeeding?

Do not take Pregabid D 50/20MG Tablet 10's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.

Can I drink alcohol while taking Pregabid D 50/20MG Tablet 10's?

Check with your doctor before drinking alcohol while taking Pregabid D 50/20MG Tablet 10's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.

How should Pregabid D 50/20MG Tablet 10's be stored?

Store Pregabid D 50/20MG Tablet 10's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.

References

DrugBank: Pregabalin

FDA Label: Pregabalin

Efficacy and Safety of Duloxetine and Pregabalin in the Treatment of Diabetic Peripheral Neuropathic Pain: A Systematic Review and Meta-Analysis

Duloxetine: A Review of Its Pharmacology, Mechanism of Action and Clinical Applications

DrugBank: Duloxetine

FDA Label: Duloxetine

Ratings & Review

Good place to get your generic medicines.

shreyas potdar

•

Reviewed on 09-04-2024

(5/5)

Very responsive staff.All drugs available at store

Ronak Makwana

•

Reviewed on 16-01-2024

(5/5)

Medkart pharmacy is doing good on saving money of customer and good work on aware to people about generic medicines.

Rinkal Surti

•

Reviewed on 23-11-2022

(5/5)

Good

tarif Malek

•

Reviewed on 15-01-2024

(5/5)

Best and Affordable medicine Store thank you medkart.

Javed Malek

•

Reviewed on 09-07-2023

(5/5)

Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

Country of Origin -

India

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PREGABID D 50/20MG TABLET 10'S

PREGABID D 50/20MG TABLET 10'S

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