PREGABID OD 100MG TABLET 10'S
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PREGABID OD 100MG TABLET 10'S

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PREGABID OD 100MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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220

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About PREGABID OD 100MG TABLET 10'S

  • PREGABID OD 100MG TABLET is a medication containing pregabalin as its active ingredient. It belongs to a class of drugs known as anticonvulsants and is primarily used to manage neuropathic pain (nerve pain) and certain types of seizures. Each tablet contains 100mg of pregabalin in an extended-release (OD) formulation, designed to provide a sustained release of the medication over a longer period. This helps in maintaining a consistent level of the drug in the bloodstream, reducing the frequency of dosing.
  • Pregabalin works by binding to a specific subunit of voltage-gated calcium channels in the central nervous system. This binding modulates the release of neurotransmitters, such as glutamate, noradrenaline, and substance P, which are involved in the transmission of pain signals. By reducing the release of these neurotransmitters, pregabalin helps to alleviate neuropathic pain. The 'OD' in PREGABID OD stands for 'Once Daily,' indicating that the tablet is formulated for once-a-day administration, improving patient compliance and convenience.
  • PREGABID OD 100MG TABLET is commonly prescribed for conditions such as diabetic neuropathy (nerve damage caused by diabetes), postherpetic neuralgia (nerve pain following shingles), fibromyalgia, and spinal cord injury-related pain. It may also be used as an adjunctive therapy in the treatment of partial seizures in adults. The extended-release formulation ensures that the medication is released slowly into the body, providing pain relief throughout the day and night.
  • The 10'S in the product name refers to the pack size, indicating that each pack contains 10 tablets. Patients should follow their doctor's instructions carefully regarding the dosage and administration of PREGABID OD 100MG TABLET. It is important to note that this medication may cause side effects such as dizziness, drowsiness, and blurred vision. Patients should exercise caution while driving or operating machinery until they know how the medication affects them.
  • Before starting PREGABID OD 100MG TABLET, patients should inform their doctor about any pre-existing medical conditions, allergies, and other medications they are taking. This information is crucial to prevent potential drug interactions and ensure the safe and effective use of the medication. Regular follow-up appointments with the doctor are necessary to monitor the patient's progress and adjust the dosage if needed. Proper storage of the medication is also important, keeping it away from moisture and direct sunlight to maintain its efficacy.

Uses of PREGABID OD 100MG TABLET 10'S

  • Treatment of Peripheral Neuropathic Pain
  • Management of Fibromyalgia
  • Adjunctive Therapy for Partial Onset Seizures
  • Relief from Postherpetic Neuralgia
  • Treatment of Diabetic Neuropathy
  • Management of Neuropathic Pain Associated with Spinal Cord Injury
  • Treatment of Generalized Anxiety Disorder (GAD)

How PREGABID OD 100MG TABLET 10'S Works

  • PREGABID OD 100MG TABLET contains Pregabalin as its active ingredient. Pregabalin is an anticonvulsant and analgesic medication that primarily works by modulating calcium channels in the central nervous system. Specifically, it binds to the α2-δ subunit of voltage-gated calcium channels, which are present on nerve cells in the brain and spinal cord. By binding to this subunit, pregabalin reduces the influx of calcium into nerve terminals.
  • This reduction in calcium influx has several downstream effects. First, it decreases the release of excitatory neurotransmitters such as glutamate, noradrenaline (norepinephrine), and substance P. These neurotransmitters are involved in the transmission of pain signals and the hyperexcitability of neurons that can lead to seizures. By reducing their release, pregabalin helps to calm overactive nerves and reduce pain sensation.
  • In the context of neuropathic pain, which is pain caused by nerve damage or dysfunction, pregabalin helps to alleviate pain by reducing the abnormal firing of neurons in the pain pathways. This can lead to a reduction in burning, shooting, or stabbing pain sensations commonly associated with nerve pain.
  • For individuals with epilepsy or seizure disorders, PREGABID OD 100MG TABLET helps to control seizures by stabilizing nerve cell activity in the brain. By reducing the release of excitatory neurotransmitters, it helps to prevent the excessive firing of neurons that can trigger seizures. The 'OD' in PREGABID OD 100MG TABLET stands for 'Once Daily', indicating that this formulation is designed for extended release and provides a consistent level of medication in the body throughout the day, improving patient compliance and reducing fluctuations in drug levels. This controlled release mechanism ensures a steady therapeutic effect, minimizing the risk of breakthrough pain or seizures.
  • Furthermore, pregabalin's mechanism of action also contributes to its anxiolytic (anti-anxiety) effects. By modulating neurotransmitter release, it can help to reduce anxiety symptoms and promote a sense of calm. While the precise mechanism of its anxiolytic effects is not fully understood, it is believed to involve the modulation of GABA (gamma-aminobutyric acid) pathways, which are important for regulating anxiety and mood.
  • In summary, PREGABID OD 100MG TABLET works by binding to calcium channels in the central nervous system, reducing the release of excitatory neurotransmitters, and stabilizing nerve cell activity. This helps to alleviate neuropathic pain, control seizures, and reduce anxiety symptoms. The extended-release formulation ensures a consistent therapeutic effect throughout the day.

Side Effects of PREGABID OD 100MG TABLET 10'SArrow

Common side effects of PREGABID OD 100MG TABLET may include: * Dizziness * Drowsiness * Headache * Dry mouth * Blurred vision * Weight gain * Difficulty concentrating * Swelling of extremities (arms, legs, hands, feet) * Increased appetite * Feeling of intoxication * Tremor Less common side effects may include: * Changes in mood or behavior, such as depression, anxiety, or irritability * Memory problems * Speech problems * Muscle twitching or cramps * Decreased sexual desire or function * Nausea, vomiting, constipation, or diarrhea * Skin rash or itching * Double vision * Loss of coordination * Falls * Confusion * Fluid retention Rare but serious side effects (seek immediate medical attention): * Severe allergic reaction (rash, itching, swelling, trouble breathing) * Suicidal thoughts or behaviors * Muscle pain, tenderness, or weakness (especially if accompanied by fever or fatigue) * Vision changes or loss * Unexplained bruising or bleeding

Safety Advice for PREGABID OD 100MG TABLET 10'SArrow

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Allergies

Allergies

Consult your Doctor

Dosage of PREGABID OD 100MG TABLET 10'SArrow

  • The recommended dosage of PREGABID OD 100MG TABLET 10'S varies depending on the individual's condition, severity of the symptoms, and response to the medication. It is crucial to strictly adhere to the dosage prescribed by your doctor. Typically, PREGABID OD is initiated at a lower dose, which may be gradually increased over time to achieve optimal therapeutic effect. Do not exceed the prescribed dose under any circumstances.
  • For neuropathic pain, the starting dose is usually 75 mg twice daily or 150 mg once daily. The dose may be increased to a maximum of 600 mg per day, depending on individual needs and tolerability. Dosage adjustments are made in increments, usually weekly, until adequate pain relief is achieved. Remember, the extended-release formulation (OD) allows for once-daily dosing, improving convenience and adherence.
  • In the treatment of epilepsy (partial seizures), PREGABID OD is generally started at 150 mg per day, administered as a single dose. The dosage can be adjusted based on the patient's response, with the maximum recommended dose being 600 mg per day. Regular monitoring by your doctor is essential to determine the most effective dose while minimizing potential side effects.
  • For the management of generalized anxiety disorder (GAD), the initial dose of PREGABID OD is often 150 mg per day. This can be increased, as needed, up to a maximum of 600 mg daily. It is essential to follow your doctor's instructions precisely and not to alter the dosage without consulting them.
  • It's important to take PREGABID OD 100MG TABLET 10'S at the same time each day to maintain a consistent level of medication in your body. This can improve its effectiveness and reduce the likelihood of side effects. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. Do not double the dose to make up for a missed one.
  • Take 'PREGABID OD 100MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of PREGABID OD 100MG TABLET 10'S?Arrow

  • If you miss a dose of Pregabid OD 100mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store PREGABID OD 100MG TABLET 10'S?Arrow

  • Keep PREGABID OD 100MG TAB 1X10 away from the reach of children and pets.
  • Store PREGABID OD 100MG TAB 1X10 at room temperature.

Benefits of PREGABID OD 100MG TABLET 10'SArrow

  • PREGABID OD 100MG Tablet offers a range of benefits for individuals suffering from neuropathic pain and certain types of seizures. This medication contains pregabalin, an active ingredient that works by modulating calcium channels in the nerve cells, thereby reducing the release of neurotransmitters involved in pain signaling and seizure activity. One of the primary benefits of PREGABID OD 100MG is its effectiveness in alleviating neuropathic pain. This type of pain arises from nerve damage or dysfunction and is often characterized by burning, shooting, or stabbing sensations. Conditions such as diabetic neuropathy, postherpetic neuralgia (shingles), and spinal cord injury can cause neuropathic pain. Pregabalin helps to reduce the intensity of pain signals, providing significant relief and improving the overall quality of life for patients.
  • Furthermore, PREGABID OD 100MG is also beneficial in managing fibromyalgia, a chronic condition characterized by widespread musculoskeletal pain accompanied by fatigue, sleep disturbances, and mood issues. The exact cause of fibromyalgia is unknown, but it is believed to involve amplified pain signals in the brain. Pregabalin helps to modulate these signals, reducing pain levels and improving other associated symptoms like sleep and fatigue. Patients with fibromyalgia often experience a significant improvement in their ability to perform daily activities and enjoy a better quality of life with the help of this medication.
  • In addition to pain management, PREGABID OD 100MG is indicated as an adjunctive therapy for partial seizures in adults. Partial seizures are a type of seizure that affects only one part of the brain. Pregabalin helps to control these seizures by reducing the excessive electrical activity in the brain. When used in combination with other antiepileptic medications, PREGABID OD 100MG can significantly reduce the frequency and severity of partial seizures, improving seizure control and preventing potential complications.
  • Another notable benefit of PREGABID OD 100MG is its once-daily, extended-release formulation. This formulation provides a steady release of the medication throughout the day, maintaining a consistent therapeutic level in the bloodstream. This can lead to improved symptom control and reduced fluctuations in pain or seizure activity. The convenience of a once-daily dosage also enhances patient compliance, making it easier to adhere to the prescribed treatment regimen.
  • PREGABID OD 100MG Tablet also helps in anxiety management. It is effective in treating generalized anxiety disorder (GAD). It works by calming the overactive nerves in the brain that cause excessive worry and tension. By reducing these symptoms, it improves the quality of life, enabling better focus, sleep, and overall emotional well-being. The calming effect helps individuals to manage daily stressors more effectively.

How to use PREGABID OD 100MG TABLET 10'SArrow

  • PREGABID OD 100MG TABLET 10'S should be taken exactly as prescribed by your doctor. It is usually taken orally with or without food. Adhering to the prescribed dosage and timing is crucial for optimal effectiveness and to minimize the risk of side effects. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water. This medication is designed for extended release, and altering it can affect how the medicine is absorbed into your body.
  • Consistency is key when taking PREGABID OD 100MG TABLET 10'S. Try to take it at the same time each day to help maintain a steady level of the medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Before starting PREGABID OD 100MG TABLET 10'S, inform your doctor about any other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Certain medications can interact with pregabalin, potentially affecting its efficacy or increasing the risk of adverse effects. Also, let your doctor know if you have any pre-existing medical conditions, especially kidney problems, heart conditions, or a history of substance abuse.
  • It is important to follow your doctor’s instructions closely and attend all scheduled follow-up appointments. Your doctor may need to adjust your dosage based on your response to the medication. Do not stop taking PREGABID OD 100MG TABLET 10'S abruptly, as this can lead to withdrawal symptoms. If you need to discontinue the medication, your doctor will gradually reduce the dosage to minimize any potential discomfort. If you experience any unusual or severe side effects, such as changes in mood or behavior, swelling, or vision problems, contact your doctor immediately.

Quick Tips for PREGABID OD 100MG TABLET 10'SArrow

  • Take PREGABID OD 100MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistent adherence to the prescribed regimen is crucial for optimal therapeutic benefits and to minimize the risk of potential side effects. This medicine is typically taken once daily, but your doctor's instructions should always take precedence.
  • Be aware that PREGABID OD 100MG TABLET 10'S may cause drowsiness or dizziness, especially when you first start taking it. Avoid driving, operating heavy machinery, or performing any tasks that require alertness until you know how the medicine affects you. Taking the medication at night may help mitigate daytime drowsiness. If dizziness persists, consult your healthcare provider.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking. PREGABID OD 100MG TABLET 10'S can interact with other substances, potentially leading to adverse effects or reduced efficacy. Pay particular attention to medications that also cause drowsiness, such as antihistamines or sedatives. A comprehensive medication history is vital for safe and effective treatment.
  • If you experience any unusual or severe side effects while taking PREGABID OD 100MG TABLET 10'S, such as swelling, difficulty breathing, vision changes, or persistent nausea, seek immediate medical attention. While many side effects are mild and temporary, some can be serious and require prompt intervention. Do not hesitate to contact your doctor or emergency services if you have concerns.
  • Do not abruptly stop taking PREGABID OD 100MG TABLET 10'S, even if you feel better. Sudden discontinuation can lead to withdrawal symptoms, such as insomnia, anxiety, and seizures. Your doctor will gradually reduce the dosage over time to minimize the risk of these symptoms. Follow their instructions carefully during the tapering process.
  • Store PREGABID OD 100MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective and safe to use until its expiration date. Check the expiration date regularly and dispose of any expired medication properly.

Food Interactions with PREGABID OD 100MG TABLET 10'SArrow

  • PREGABID OD 100MG TABLET 10'S can be taken with or without food. Food does not significantly affect the absorption of this medication. However, it is advisable to take it at the same time each day to maintain consistent blood levels.

FAQs

What is Pregabid OD 100mg Tablet used for?Arrow

Pregabid OD 100mg Tablet is primarily used to treat neuropathic pain (pain due to nerve damage) and fibromyalgia. It may also be used to control certain types of seizures (fits) in adults.

How does Pregabid OD 100mg Tablet work?Arrow

Pregabid OD 100mg Tablet works by reducing the pain signals in the brain. It reduces the release of chemicals that cause pain and seizures.

What are the common side effects of Pregabid OD 100mg Tablet?Arrow

Common side effects of Pregabid OD 100mg Tablet include dizziness, sleepiness, blurred vision, weight gain, and dry mouth.

Can Pregabid OD 100mg Tablet be taken with or without food?Arrow

Pregabid OD 100mg Tablet can be taken with or without food. It is best to take it at the same time each day.

Is Pregabid OD 100mg Tablet addictive?Arrow

Pregabid OD 100mg Tablet can be habit-forming. Take it only for the dose and duration prescribed by your doctor.

What happens if I miss a dose of Pregabid OD 100mg Tablet?Arrow

If you miss a dose of Pregabid OD 100mg Tablet, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

Is it safe to stop taking Pregabid OD 100mg Tablet abruptly?Arrow

Do not stop taking Pregabid OD 100mg Tablet abruptly. This can cause withdrawal symptoms. Talk to your doctor about gradually reducing your dose.

Can Pregabid OD 100mg Tablet interact with other medications?Arrow

Pregabid OD 100mg Tablet can interact with certain other medications, such as opioid painkillers, anti-anxiety drugs, and sleeping pills. Tell your doctor about all the medications you are taking.

How should I store Pregabid OD 100mg Tablet?Arrow

Store Pregabid OD 100mg Tablet at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can pregnant women take Pregabid OD 100mg Tablet?Arrow

Pregnant women should not take Pregabid OD 100mg Tablet unless specifically directed by a doctor. It may harm the unborn baby.

Can breastfeeding women take Pregabid OD 100mg Tablet?Arrow

Breastfeeding women should not take Pregabid OD 100mg Tablet as it may pass into breast milk and harm the baby.

What are the symptoms of an overdose of Pregabid OD 100mg Tablet?Arrow

Symptoms of an overdose of Pregabid OD 100mg Tablet may include severe drowsiness, confusion, difficulty speaking, and loss of consciousness.

Does Pregabid OD 100mg Tablet affect the ability to drive?Arrow

Pregabid OD 100mg Tablet can cause dizziness or sleepiness, which may impair the ability to drive. Do not drive or operate machinery until you know how it affects you.

What should I tell my doctor before taking Pregabid OD 100mg Tablet?Arrow

Before taking Pregabid OD 100mg Tablet, tell your doctor about all your medical conditions, allergies, and all medications you are taking.

Are there alternatives to Pregabid OD 100mg Tablet available?Arrow

Yes, there are alternatives to Pregabid OD 100mg Tablet available. The best option for you will depend on your condition and medical history. Talk to your doctor about other options. Gabapentin could be an alternative.

References

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FDA Prescribing Information for PREGABALIN Extended-Release Tablets. This document provides detailed information on the drug's uses, dosage, side effects, and clinical pharmacology.

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DrugBank entry for Pregabalin. DrugBank provides comprehensive information on drug properties, mechanisms of action, and interactions.

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Pharmacokinetics and dose proportionality of extended-release pregabalin. This study investigates the pharmacokinetic properties of an extended-release formulation of pregabalin.

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European Medicines Agency (EMA) assessment report on Lyrica (pregabalin). This report provides a comprehensive evaluation of the drug's efficacy and safety.

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Pregabalin - StatPearls - NCBI Bookshelf. A review of pregabalin, its mechanism of action, indications, contraindications, and adverse effects.

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