PREGASIA CAPSULE 10'S

How PREGASIA CAPSULE 10'S Works

• PREGASIA CAPSULE 10'S is a combination medicine primarily used to manage neuropathic pain and fibromyalgia. Its effectiveness stems from the synergistic action of its two active ingredients: Pregabalin and Methylcobalamin. Understanding how each component works helps illuminate the overall mechanism of action of PREGASIA CAPSULE.
• Pregabalin, an analogue of gamma-aminobutyric acid (GABA), plays a crucial role in reducing pain signals transmitted by the nerves. While not directly binding to GABA receptors, Pregabalin binds to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, Pregabalin modulates the influx of calcium into nerve terminals. This modulation results in a decrease in the release of several excitatory neurotransmitters, including glutamate, noradrenaline, and substance P. These neurotransmitters are involved in the transmission of pain signals. Therefore, by reducing their release, Pregabalin effectively dampens the overactivity of nerves that cause neuropathic pain.
• Methylcobalamin, a form of Vitamin B12, plays a vital role in nerve health and regeneration. In the context of neuropathic pain, Methylcobalamin helps in the myelination and repair of damaged nerve fibers. Myelin is a fatty substance that insulates nerve fibers and ensures efficient transmission of nerve impulses. Damage to myelin sheaths can lead to impaired nerve function and neuropathic pain. Methylcobalamin supports the synthesis of myelin, thereby improving nerve conduction velocity and reducing abnormal nerve firing that contributes to pain. Additionally, Methylcobalamin acts as a neuroprotective agent, protecting nerve cells from further damage and promoting their survival.
• The combination of Pregabalin and Methylcobalamin in PREGASIA CAPSULE 10'S provides a comprehensive approach to managing neuropathic pain. Pregabalin reduces the transmission of pain signals, while Methylcobalamin promotes nerve regeneration and protects against further nerve damage. This dual action helps alleviate pain, improve nerve function, and enhance the overall quality of life for individuals suffering from neuropathic pain and fibromyalgia. The synergistic effect of these two components ensures more effective pain relief compared to using either component alone.
• In summary, PREGASIA CAPSULE 10'S works by modulating calcium channels to reduce excitatory neurotransmitter release (Pregabalin) and by supporting nerve regeneration and protection (Methylcobalamin), leading to pain relief and improved nerve function.

Common side effects of Pregasia Capsule may include: Dizziness, Sleepiness, Headache, Dry mouth, Blurred vision, Weight gain, Difficulty concentrating, Swelling of hands and feet. Less common side effects may include: Mood changes, Memory problems, Tremors, Muscle twitching, Decreased libido, Erectile dysfunction, Changes in appetite, Constipation, Vomiting, Flatulence. Rare but serious side effects include: Severe allergic reactions (rash, itching, swelling), Suicidal thoughts, Liver problems (yellowing of skin or eyes), Muscle pain or weakness, Vision changes. This is not an exhaustive list, and you should consult your doctor if you experience any unusual or bothersome symptoms while taking Pregasia Capsule.

• If you miss a dose of Pregasia Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep PREGASIA CAP 1X10 away from the reach of children and pets.
• Store PREGASIA CAP 1X10 at room temperature.

• Take Pregasia Capsule exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures optimal effectiveness and minimizes potential side effects. Consistent adherence to the prescribed regimen is crucial for managing your condition effectively.
• Be mindful of potential side effects. Common side effects may include dizziness, drowsiness, or dry mouth. If these persist or worsen, inform your doctor promptly. Avoid activities requiring alertness, such as driving, until you know how Pregasia affects you. Report any severe or unusual symptoms to your healthcare provider immediately.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Pregasia can interact with other substances, potentially altering their effects or increasing the risk of adverse reactions. A complete medication history helps your doctor ensure your safety and optimize your treatment plan.
• Store Pregasia Capsules in a cool, dry place, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Proper storage maintains the drug's integrity and effectiveness. Do not use the medication if it has expired or shows signs of damage.
• Maintain a healthy lifestyle to support the effectiveness of Pregasia. This includes a balanced diet, regular exercise, and sufficient sleep. Avoid excessive alcohol consumption, as it may exacerbate side effects. A healthy lifestyle complements the medication and promotes overall well-being.

• PREGASIA CAPSULE 10'S can be taken with or without food, as food does not significantly affect its absorption or effectiveness. However, it is advisable to maintain a consistent pattern of taking it at the same time each day to help you remember.