PREGASTAR PLUS SR 75MG TABLET 10'S

How PREGASTAR PLUS SR 75MG TABLET 10'S Works

• PREGASTAR PLUS SR 75MG TABLET 10'S is a combination medication designed to manage neuropathic pain and certain types of seizures. It contains two active ingredients: Pregabalin and Methylcobalamin. Each component works through distinct mechanisms to alleviate pain and support nerve health.
• Pregabalin, an analogue of gamma-aminobutyric acid (GABA), plays a crucial role in reducing pain signals. It binds to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, pregabalin modulates the influx of calcium into nerve terminals. This modulation inhibits the release of several excitatory neurotransmitters, such as glutamate, noradrenaline, and substance P. These neurotransmitters are involved in the transmission of pain signals. By reducing their release, pregabalin effectively decreases the excitability of neurons and reduces the perception of pain. This mechanism is particularly effective for neuropathic pain, which arises from nerve damage or dysfunction.
• Methylcobalamin, a form of vitamin B12, is essential for nerve health and function. It participates in various metabolic processes within nerve cells, including myelin synthesis. Myelin is a fatty substance that insulates nerve fibers, protecting them and facilitating the efficient transmission of electrical signals. Methylcobalamin also promotes nerve regeneration and repair. In cases of nerve damage, it helps rebuild the myelin sheath and restore nerve function. Additionally, Methylcobalamin can act as a neuroprotective agent by reducing oxidative stress and inflammation in the nervous system. This neuroprotective effect can further contribute to pain relief and improved nerve health.
• The synergistic action of Pregabalin and Methylcobalamin provides comprehensive pain relief and nerve support. Pregabalin reduces the transmission of pain signals, while Methylcobalamin promotes nerve healing and reduces nerve damage. Together, they address both the symptomatic relief of pain and the underlying nerve dysfunction contributing to the pain. The extended-release (SR) formulation of PREGASTAR PLUS ensures a gradual release of the medication, providing sustained pain relief throughout the day and improving patient compliance.
• In summary, PREGASTAR PLUS SR 75MG TABLET 10'S works by reducing the release of excitatory neurotransmitters involved in pain signaling through Pregabalin's action on calcium channels, and by supporting nerve health and regeneration through Methylcobalamin's role in myelin synthesis and neuroprotection. This dual mechanism effectively manages neuropathic pain and supports overall nerve function.

Common side effects of Pregastar Plus SR 75mg Tablet may include: Dizziness, Sleepiness, Tiredness, Uncoordinated body movements. Less common but potentially serious side effects include: Blurred vision, Double vision, Swelling of the face, mouth, or tongue, Difficulty breathing, Skin rash, Itching, Nausea, Vomiting, Constipation, Diarrhea, Dry mouth, Weight gain, Memory problems, Difficulty concentrating, Confusion, Mood changes, Depression, Anxiety, Nervousness, Tremors, Muscle pain, Weakness, Peripheral neuropathy (numbness, tingling, or burning pain in the hands or feet), Decreased libido, Erectile dysfunction. This is not an exhaustive list, and other side effects may occur. Contact your doctor immediately if you experience any unusual or severe symptoms.

• If you miss a dose of PREGASTAR PLUS SR 75MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGASTAR PLUS SR 75MG TAB 1X10 away from the reach of children and pets.
• Store PREGASTAR PLUS SR 75MG TAB 1X10 at room temperature.

• **Take Pregastar Plus SR 75mg Tablet as Prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not alter the dosage without consulting your healthcare provider, even if you feel better or worse. Consistency is key for optimal results.
• **Be Aware of Potential Side Effects:** Pregastar Plus SR 75mg Tablet may cause side effects such as dizziness, drowsiness, blurred vision, or gastrointestinal issues. If you experience any bothersome or persistent side effects, inform your doctor promptly. Avoid activities requiring alertness until you know how the medication affects you.
• **Inform Your Doctor of Other Medications:** Before starting Pregastar Plus SR 75mg Tablet, disclose all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Drug interactions can affect how Pregastar Plus SR 75mg Tablet works and increase the risk of side effects. Pay special attention to medications that cause drowsiness or affect mood.
• **Maintain a Healthy Lifestyle:** While taking Pregastar Plus SR 75mg Tablet, prioritize a healthy lifestyle. This includes eating a balanced diet, engaging in regular exercise, and getting enough sleep. Avoid excessive alcohol consumption, as it can worsen side effects and interfere with the medication's effectiveness. A healthy lifestyle can complement the effects of the medication and improve your overall well-being.
• **Store Pregastar Plus SR 75mg Tablet Properly:** Keep Pregastar Plus SR 75mg Tablet in a safe place, out of reach of children and pets. Store it at room temperature, away from direct sunlight and moisture. Do not store it in the bathroom. Properly dispose of any unused medication according to your local regulations. Check the expiration date and do not use the medication if it has expired.
• **Take with or without food:** Pregastar Plus SR 75mg Tablet can be taken with or without food. However, it's important to maintain consistency in how you take it to ensure optimal absorption and effectiveness. Choose one method and stick to it, unless otherwise directed by your doctor.
• **Avoid Abrupt Discontinuation:** Do not stop taking Pregastar Plus SR 75mg Tablet suddenly, as this can lead to withdrawal symptoms or a worsening of your condition. If you need to discontinue the medication, your doctor will gradually reduce the dosage to minimize the risk of adverse effects. Always consult your doctor before making any changes to your medication regimen.
• **Pregastar Plus SR 75mg Tablet and Pregnancy/Breastfeeding:** If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of taking Pregastar Plus SR 75mg Tablet with your doctor. The medication may not be safe for use during pregnancy or breastfeeding, and your doctor can help you make an informed decision.

• PREGASTAR PLUS SR 75MG TABLET 10'S can be taken with or without food. However, taking it at a consistent time each day is recommended to maintain a steady level of medication in your body. Be mindful that while food doesn't directly interfere with the drug's absorption, high-fat meals might slightly delay it. Avoid alcohol consumption while taking this medication, as it can increase the risk of side effects like drowsiness and dizziness.