PREGEB M OD 150MG TABLET 10'S

How PREGEB M OD 150MG TABLET 10'S Works

• PREGEB M OD 150MG TABLET 10'S is a combination medication containing Pregabalin and Methylcobalamin. It is primarily used to treat neuropathic pain, a type of nerve pain that can occur due to various conditions such as diabetes, shingles, or injuries. Understanding how each component works is crucial to appreciating the overall effectiveness of this medication.
• Pregabalin, an active ingredient in PREGEB M OD, is an anticonvulsant and analgesic. It primarily works by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system. These calcium channels play a crucial role in the release of neurotransmitters, chemical messengers that transmit signals between nerve cells. By binding to this subunit, Pregabalin modulates calcium influx into nerve terminals, thereby reducing the release of excitatory neurotransmitters such as glutamate, noradrenaline, and substance P. This reduction in neurotransmitter release helps to dampen the overactivity of nerve cells that contribute to neuropathic pain. In simpler terms, Pregabalin calms down the overexcited nerves that are sending pain signals.
• Methylcobalamin, the other key component of PREGEB M OD, is a form of vitamin B12. It plays a vital role in the health and maintenance of nerve cells. Methylcobalamin helps in the regeneration of damaged nerves and promotes the formation of myelin, a protective sheath around nerve fibers. Myelin is essential for the efficient transmission of nerve impulses. In conditions like diabetic neuropathy, nerve damage often occurs due to impaired metabolism and reduced myelin sheath integrity. Methylcobalamin supplementation helps to restore myelin and improve nerve function. Furthermore, Methylcobalamin is involved in various metabolic pathways that support nerve cell health, including the synthesis of nucleic acids and proteins necessary for nerve repair. By contributing to nerve regeneration and overall nerve health, Methylcobalamin complements the pain-reducing effects of Pregabalin.
• In summary, PREGEB M OD 150MG TABLET 10'S works through a dual mechanism. Pregabalin reduces the overactivity of nerves by modulating calcium channel activity and reducing the release of excitatory neurotransmitters. Methylcobalamin promotes nerve regeneration and improves nerve function by supporting myelin formation and overall nerve cell health. This combination approach addresses both the symptomatic relief of pain (through Pregabalin) and the underlying nerve damage (through Methylcobalamin), making it an effective treatment for neuropathic pain.
• The 'OD' in PREGEB M OD stands for 'Once Daily', indicating that this formulation is designed for extended release, providing a sustained therapeutic effect over 24 hours with a single dose. This can improve patient compliance and convenience compared to multiple daily dosing regimens.

The following side effects may occur while using PREGEB M OD 150MG TABLET 10'S. It is important to consult with your doctor if you experience any of these, especially if they persist or worsen: **Common Side Effects:** * Dizziness * Sleepiness * Headache * Dry mouth * Blurred vision * Weight gain * Difficulty concentrating * Peripheral edema (swelling in the extremities) * Increased appetite * Tremor * Nausea * Constipation * Fatigue **Uncommon Side Effects:** * Mood changes (e.g., depression, anxiety, irritability) * Memory problems * Speech difficulties * Coordination problems * Muscle twitching or cramps * Sexual dysfunction * Vision changes (e.g., double vision) * Hearing problems * Increased sweating * Skin rash * Changes in blood pressure * Heart rhythm disturbances * Fluid retention * Allergic reactions (e.g., swelling of the face, lips, tongue, or throat; difficulty breathing) * Loss of consciousness * Muscle pain * Weakness **Rare Side Effects:** * Suicidal thoughts * Severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis) * Rhabdomyolysis (muscle breakdown) * Pancreatitis * Hepatitis (liver inflammation) **Important Note:** This is not an exhaustive list of all possible side effects. If you experience any unusual symptoms, contact your doctor immediately.

• If you miss a dose of PREGEB M OD 150MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep PREGEB M OD 150MG TAB 1X10 away from the reach of children and pets.
• Store PREGEB M OD 150MG TAB 1X10 at room temperature.

• Take PREGEB M OD 150MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medicine without consulting your healthcare provider. This medication is designed for once-daily use, so adhere to the prescribed schedule for optimal results.
• PREGEB M OD 150MG TABLET 10'S can be taken with or without food. However, maintaining a consistent pattern of administration (either always with food or always without) can help stabilize its effects and reduce potential side effects. Consult your doctor for specific dietary recommendations.
• Be aware of potential side effects. Common side effects include dizziness, drowsiness, and peripheral edema (swelling in the extremities). If these side effects persist or worsen, contact your doctor immediately. Avoid activities requiring alertness, such as driving or operating machinery, until you know how this medication affects you.
• Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking before starting PREGEB M OD 150MG TABLET 10'S. This is crucial to avoid potential drug interactions that could reduce the effectiveness of PREGEB M OD or increase the risk of adverse effects. Pay special attention to other medications that also cause drowsiness or affect nerve function.
• Store PREGEB M OD 150MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• If you have kidney problems, liver issues, or a history of heart conditions, inform your doctor about it before starting PREGEB M OD 150MG TABLET 10'S. Your doctor may need to adjust the dosage or monitor you more closely. Regular check-ups and blood tests may be required to ensure the medication is working safely and effectively.
• PREGEB M OD 150MG TABLET 10'S is often prescribed for neuropathic pain and fibromyalgia. Be patient and consistent with the treatment, as it may take several weeks to experience the full benefits. Keep a journal of your symptoms and any side effects you experience to share with your doctor during follow-up appointments.
• Avoid alcohol consumption while taking PREGEB M OD 150MG TABLET 10'S, as it can increase the risk of drowsiness and other side effects. Alcohol can also interfere with the medication's effectiveness. Consult with your healthcare provider if you have concerns about alcohol use.
• Discuss any plans for surgery or dental procedures with your doctor if you are taking PREGEB M OD 150MG TABLET 10'S. The medication may need to be temporarily discontinued before the procedure to minimize potential complications related to anesthesia or bleeding.
• If you experience any unusual symptoms such as changes in mood, vision problems, or signs of an allergic reaction (rash, itching, swelling), seek immediate medical attention. These symptoms could indicate a serious adverse reaction to the medication.

• PREGEB M OD 150MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent medicine levels in the body.
• There are no specific food items to avoid while taking this medicine. Follow your doctor's dietary instructions if any.