PURADINE GARGLE 100 ML

How PURADINE GARGLE 100 ML Works

• PURADINE Gargle 100 ML harnesses the potent antimicrobial action of povidone-iodine to combat a wide array of pathogens present in the oral cavity and throat. Povidone-iodine is a complex of iodine and a polymer, which slowly releases free iodine. It is this free iodine that exhibits a broad spectrum of microbicidal activity, effectively killing bacteria, viruses, fungi, and protozoa upon contact. This gargle works through several key mechanisms:
• **Oxidation:** Free iodine acts as a strong oxidizing agent. It disrupts the structure and function of essential microbial components like proteins, enzymes, and nucleic acids. By oxidizing these vital molecules, iodine interferes with the metabolic processes and structural integrity of the microorganisms, leading to their inactivation and death.
• **Iodination:** Iodine directly iodinates lipids and amino acids within microbial cells. This iodination process alters the structure of these molecules, disrupting their normal function. For example, iodination of proteins can lead to their denaturation, rendering them non-functional.
• **Cell Wall Disruption:** Povidone-iodine can disrupt the cell walls and membranes of microorganisms. This disruption compromises the integrity of the cell, causing leakage of intracellular contents and ultimately leading to cell lysis (bursting). This is particularly effective against bacteria and fungi.
• The sustained release of free iodine from the povidone-iodine complex ensures prolonged antimicrobial activity. This prolonged action helps to reduce the microbial load in the mouth and throat, providing relief from infections and preventing their spread. The gargle's formulation allows it to reach all areas of the oral cavity and throat, ensuring comprehensive coverage and effective disinfection.
• Furthermore, PURADINE Gargle 100 ML's efficacy is not significantly affected by organic matter like saliva or blood, unlike some other antiseptics. This means that it remains effective even in the presence of these substances, ensuring reliable antimicrobial action.
• In summary, PURADINE Gargle 100 ML works by releasing free iodine, which then oxidizes and iodinates microbial components, disrupts cell walls, and ultimately kills a broad range of microorganisms responsible for oral and throat infections. Its sustained release and resistance to interference from organic matter make it a reliable and effective gargle for maintaining oral hygiene and treating infections.

Common side effects of Puradine Gargle may include: * Taste alterations * Burning sensation in the mouth * Dryness of mouth * Sore throat * Increased salivation Less common or rare side effects may include: * Allergic reactions (rash, itching, hives) * Swelling of the mouth or throat * Difficulty breathing * Thyroid problems (with prolonged or excessive use) * Staining of teeth or oral mucosa (temporary) * Elevated sodium levels in the blood **If you experience any of these side effects or any other unusual symptoms, discontinue use and consult your doctor or pharmacist immediately.**

• If you miss a dose of Puradine Gargle, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep PURADINE GARGLE 100ML away from the reach of children and pets.
• Store PURADINE GARGLE 100ML at room temperature.

• For optimal results, gargle with undiluted PURADINE GARGLE 100 ML for 30 seconds, ensuring contact with all affected areas of the throat and mouth. Avoid swallowing the solution.
• Use PURADINE GARGLE 100 ML as directed by your healthcare professional, typically 2-4 times daily, especially after meals or when experiencing discomfort. Consistency is key for effective treatment.
• Store PURADINE GARGLE 100 ML at room temperature, away from direct sunlight and heat. Keep the bottle tightly closed to maintain its potency and prevent contamination. Proper storage ensures its efficacy over time.
• Before using PURADINE GARGLE 100 ML, inform your doctor or pharmacist if you have any allergies, particularly to iodine, or any thyroid conditions. Iodine sensitivity can lead to adverse reactions.
• If throat irritation persists or worsens after several days of using PURADINE GARGLE 100 ML, discontinue use and consult your healthcare provider. Prolonged or worsening symptoms may indicate a different underlying issue requiring specific medical attention.
• To prevent staining of teeth or clothing, avoid contact with fabrics and rinse your mouth thoroughly with water after gargling with PURADINE GARGLE 100 ML. Stains can be difficult to remove, so take precautions.
• PURADINE GARGLE 100 ML is for oral use only. Avoid contact with eyes. If accidental contact occurs, rinse immediately and thoroughly with water. Seek medical attention if irritation persists.

• There are no known food interactions with PURADINE GARGLE 100 ML. You can use it before or after meals.
• However, it is generally recommended to avoid eating or drinking anything for at least 30 minutes after using the gargle to allow the medication to work effectively.