RELGIN 0.5MG TABLET 10'S

How RELGIN 0.5MG TABLET 10'S Works

• RELGIN 0.5MG TABLET 10'S contains repaglinide, which is an oral hypoglycemic agent belonging to the meglitinide class. It is primarily used to manage type 2 diabetes mellitus by stimulating the release of insulin from the pancreas. The mechanism of action of repaglinide involves its binding to specific receptors on the surface of pancreatic beta cells. These receptors are associated with ATP-sensitive potassium (KATP) channels.
• In healthy individuals, glucose metabolism leads to an increase in intracellular ATP levels within the beta cells. This rise in ATP causes the KATP channels to close. The closure of these channels results in the depolarization of the beta cell membrane. This depolarization opens voltage-gated calcium channels, allowing calcium ions to flow into the cell. The influx of calcium triggers the fusion of insulin-containing granules with the cell membrane, leading to the release of insulin into the bloodstream.
• Repaglinide essentially mimics the effect of glucose on the beta cells. By binding to the KATP channels, it promotes their closure, even in the absence of elevated glucose levels. This leads to membrane depolarization, calcium influx, and subsequent insulin release. The effect of repaglinide is glucose-dependent to some extent; it stimulates insulin release more effectively when glucose levels are higher. This reduces the risk of hypoglycemia compared to sulfonylureas, which can stimulate insulin release even when blood glucose levels are low.
• The increased insulin levels help to lower postprandial (after-meal) blood glucose levels. This makes repaglinide particularly effective at controlling blood sugar spikes that occur after eating. By improving glycemic control, RELGIN 0.5MG TABLET 10'S helps to reduce the long-term complications associated with type 2 diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).

Possible side effects of RELGIN 0.5MG TABLET may include: Common: Nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, headache, dizziness, drowsiness, weakness, fatigue, insomnia (difficulty sleeping), anxiety, nervousness, skin rash, itching. Uncommon: Changes in menstrual cycle, breast pain or enlargement, decreased sexual desire, hair loss, weight changes, fluid retention (edema), allergic reactions (hives, swelling), blurred vision, palpitations, muscle cramps, changes in liver function tests. Rare: Blood clots, stroke, heart attack, severe allergic reaction (anaphylaxis). This is not an exhaustive list. Consult your doctor if you experience any unusual or severe side effects.

• If you forget to take a dose of RELGIN 0.5MG TABLET 10'S, take it as soon as you remember, unless it is nearly time for your next dose. In this case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the one you missed.

• Keep RELGIN 0.5MG TAB 1X10 away from the reach of children and pets.
• Store RELGIN 0.5MG TAB 1X10 at room temperature.

• **Take RELGIN 0.5MG TABLET as prescribed:** Always adhere to your doctor's instructions regarding dosage and frequency. Do not alter the dosage without consulting your healthcare provider, even if you feel better or worse.
• **Consistency is Key:** For optimal results, take RELGIN 0.5MG TABLET at the same time each day. This helps maintain a consistent level of the medication in your body, maximizing its effectiveness. Use an alarm or reminder app if needed.
• **Be Patient:** It may take several weeks to experience the full benefits of RELGIN 0.5MG TABLET. Do not get discouraged if you don't see immediate improvement. Continue taking the medication as prescribed and discuss any concerns with your doctor.
• **Monitor for Side Effects:** Be aware of potential side effects, which may include nausea, dizziness, or headaches. If you experience any bothersome or persistent side effects, contact your doctor promptly. Do not stop taking the medication without medical advice.
• **Lifestyle Adjustments:** Discuss with your doctor any lifestyle adjustments that might complement your medication. This could include dietary changes, exercise, or stress management techniques. A holistic approach can improve overall well-being alongside the medication's effects.

• RELGIN 0.5MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent medicine levels in the body.
• Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it may increase the concentration of the medicine in your blood and potentially increase side effects.