REVOLIZER DEVICE

How REVOLIZER DEVICE Works

• The Revolizer device is a multi-dose dry powder inhaler (MDPI) designed for the effective delivery of inhaled medications directly to the lungs. Its unique design ensures optimal drug dispersion and minimal drug wastage, maximizing therapeutic benefits for patients with respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD). Unlike some inhalers that require precise coordination between actuation and inhalation, the Revolizer simplifies the process, making it easier for patients of all ages to use effectively.
• The core principle of the Revolizer lies in its ability to create a fine, dispersible powder cloud from the medication contained within a capsule. When the patient inhales through the device, air is drawn in, passing through the capsule chamber. This airflow causes the capsule to rotate, and the internal design of the Revolizer facilitates the efficient release of the powdered medication. The released powder is then de-aggregated into smaller particles, ensuring they can reach the small airways of the lungs where they are most effective.
• The device's low resistance to airflow is a key feature, particularly beneficial for patients with compromised lung function. This low resistance reduces the effort required for inhalation, allowing for a more complete and consistent dose delivery. The Revolizer is also designed to provide visual and auditory feedback, indicating successful capsule piercing and powder dispersion, giving the patient confidence that the medication is being properly administered.
• Furthermore, the Revolizer's multi-dose capability allows patients to carry multiple doses in a single, convenient device, eliminating the need to carry separate doses of medication. This can be particularly advantageous for patients who require frequent medication or those who are traveling. The design also minimizes the impact of humidity on the drug, ensuring consistent and reliable dosing.
• Proper use of the Revolizer involves a few simple steps: First, the patient opens the device and inserts a capsule containing the medication into the designated chamber. Next, the device is closed, and the capsule is pierced using the integrated mechanism. Finally, the patient exhales completely, then seals their lips around the mouthpiece and inhales deeply and forcefully. A distinct clicking sound usually indicates successful capsule piercing. After inhalation, the patient holds their breath for a few seconds before exhaling slowly. The empty capsule is then removed and discarded. Regular cleaning of the Revolizer, according to the manufacturer's instructions, is essential to maintain its optimal performance and prevent clogging.

The Revolizer device itself is generally safe, but side effects usually arise from the medication being inhaled. These side effects vary depending on the specific drug used with the Revolizer. Common side effects associated with inhaled medications may include: * **Coughing:** A common reflex triggered by inhalation. * **Sore throat:** Irritation from the inhaled powder. * **Hoarseness:** Changes in voice due to throat irritation. * **Dry mouth:** Some medications can reduce saliva production. * **Throat irritation:** A scratchy or uncomfortable feeling. * **Headache:** A less common side effect, but possible. * **Dizziness:** Feeling lightheaded. * **Nausea:** Feeling sick to your stomach. * **Fungal infection in the mouth (oral thrush):** This is more common with inhaled corticosteroids. Rinsing your mouth after each use can help prevent this. * **Palpitations (fast or irregular heartbeat):** Some bronchodilators can cause this. Less common, but more serious side effects (seek immediate medical attention if you experience these): * **Severe allergic reactions:** Symptoms include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, and trouble breathing. * **Paradoxical bronchospasm:** A sudden tightening of the airways, making breathing difficult. This is the opposite of what the medication is intended to do. * **Increased heart rate or blood pressure:** Significant increases can be dangerous for people with heart conditions.

• If you miss a dose of medication using the Revolizer device, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

• Keep REVOLIZER DEVICE away from the reach of children and pets.
• Store REVOLIZER DEVICE at room temperature.

• **Understand Your Revolizer:** Before using, familiarize yourself with all parts of the Revolizer device. Know how to open, load the capsule, pierce it, and inhale the medication. Refer to the instruction manual for detailed diagrams and explanations. This will ensure proper usage and optimal drug delivery.
• **Proper Loading Technique is Key:** Always load the capsule into the Revolizer chamber correctly. Ensure the capsule is placed in the designated slot before closing the device. Avoid forcing the capsule, as this could damage the device or the capsule itself. A properly loaded capsule ensures consistent dosing.
• **Master the Inhalation Technique:** Effective drug delivery depends on proper inhalation. Breathe out completely before placing the Revolizer mouthpiece into your mouth. Seal your lips tightly around the mouthpiece, inhale deeply and forcefully through your mouth. Hold your breath for 5-10 seconds to allow the medication to reach your lungs. Exhale slowly. This ensures maximum drug absorption.
• **Listen for the Capsule Piercing:** After loading the capsule and closing the Revolizer, there's usually a mechanism to pierce the capsule. Listen for the clicking or piercing sound which indicates that the capsule has been properly punctured. This step is crucial for releasing the medication powder during inhalation. If you don't hear the sound, re-pierce the capsule according to the device instructions.
• **Regular Cleaning is Essential:** To maintain hygiene and device performance, clean your Revolizer regularly. Use a clean, dry cloth to wipe the mouthpiece and capsule chamber after each use. Do not use water or liquids, as this can damage the device or cause the medication powder to clump. Store the Revolizer in a clean, dry place away from moisture and extreme temperatures. This will ensure the longevity and proper functioning of your device.

• REVOLIZER DEVICE is not known to interact with food. You can use the device before or after food.