ROMY 250MCG INJECTION 0.5 ML
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ROMY 250MCG INJECTION 0.5 ML
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ROMY 250MCG INJECTION 0.5 ML

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ROMY 250MCG INJECTION 0.5 ML

By INTAS PHARMACEUTICALS LIMITED

MRP

3736.71

₹3176.2

15 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Manoj Shah

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About ROMY 250MCG INJECTION 0.5 ML

  • ROMY 250MCG INJECTION 0.5 ML is a cutting-edge medication designed to address thrombocytopenia, a condition characterized by a low platelet count in the blood. Platelets are crucial for blood clotting, and when their levels are deficient, it can lead to excessive bleeding and bruising. This injection offers a targeted approach to stimulate platelet production, helping patients regain healthy blood cell counts and minimize the risks associated with thrombocytopenia.
  • The active ingredient in ROMY 250MCG INJECTION is romiplostim, a thrombopoietin (TPO) receptor agonist. Romiplostim works by mimicking the effects of TPO, a natural hormone in the body that regulates platelet production in the bone marrow. By binding to and activating the TPO receptor on bone marrow cells, romiplostim effectively boosts the production of platelets, leading to a significant increase in platelet counts in individuals with thrombocytopenia.
  • This medication is typically administered via subcutaneous injection, offering a convenient and manageable way for patients to receive treatment. The dosage and frequency of injections are determined by a healthcare professional based on the individual's specific needs and platelet levels. Regular monitoring of blood counts is essential to ensure optimal treatment outcomes and to adjust the dosage as needed.
  • ROMY 250MCG INJECTION 0.5 ML is primarily prescribed for patients with immune thrombocytopenic purpura (ITP), a condition where the immune system mistakenly attacks and destroys platelets. It is also used in other conditions causing thrombocytopenia, as determined by a healthcare provider. This injection is a valuable tool in managing thrombocytopenia, helping patients lead more active and healthier lives by reducing the risk of bleeding complications.
  • It is important to note that ROMY 250MCG INJECTION should be administered under the supervision of a qualified healthcare professional. Patients should discuss their medical history, current medications, and any potential allergies with their doctor before starting treatment. Potential side effects and risks associated with the injection should also be thoroughly discussed to ensure informed decision-making and optimal patient care.

Uses of ROMY 250MCG INJECTION 0.5 ML

  • Treatment of Thrombocytopenia (low platelet count)
  • Treatment of Purpura (easy bruising or bleeding)
  • Treatment of Immune Thrombocytopenic Purpura (ITP)
  • Treatment of Chronic Immune Thrombocytopenic Purpura (CITP)
  • Increasing platelet count before surgery
  • Increasing platelet count before certain medical procedures

How ROMY 250MCG INJECTION 0.5 ML Works

  • ROMY 250MCG INJECTION 0.5 ML contains Romiplostim as its active ingredient. Romiplostim is a thrombopoietin (TPO) receptor agonist. TPO is a protein in the body that stimulates the bone marrow to produce platelets. Platelets are essential for blood clotting and preventing excessive bleeding.
  • In individuals with immune thrombocytopenic purpura (ITP), the body's immune system mistakenly attacks and destroys platelets, leading to a low platelet count. ROMY 250MCG INJECTION 0.5 ML works by mimicking the effects of TPO, thereby stimulating the bone marrow to produce more platelets. This helps to increase the platelet count in the blood, reducing the risk of bleeding.
  • Specifically, Romiplostim binds to and activates the TPO receptor on megakaryocytes, which are the cells in the bone marrow responsible for platelet production. This activation triggers a cascade of intracellular signaling pathways that promote the proliferation, differentiation, and maturation of megakaryocytes, ultimately leading to increased platelet production and release into the bloodstream.
  • Unlike TPO itself, Romiplostim is a peptibody, which is a synthetic protein designed to have a longer duration of action in the body. This means that it does not get cleared from the body as quickly as natural TPO, allowing for sustained stimulation of platelet production with less frequent dosing. This contributes to a more stable platelet count over time.
  • The increased platelet count helps in reducing the risk of bleeding episodes and improving the overall quality of life for individuals suffering from ITP. ROMY 250MCG INJECTION 0.5 ML is administered via subcutaneous injection, allowing for easy self-administration after proper training and guidance from a healthcare professional. The dosage is carefully adjusted based on the individual's platelet count to achieve the desired therapeutic effect.
  • It is crucial to use ROMY 250MCG INJECTION 0.5 ML under the supervision of a qualified healthcare provider who can monitor the platelet count and adjust the dosage as necessary. This ensures the best possible outcome and minimizes potential risks associated with the medication. Treatment with Romiplostim aims to maintain platelet counts at a level that reduces bleeding risks without causing excessive thrombocytosis.

Side Effects of ROMY 250MCG INJECTION 0.5 MLArrow

Common side effects of ROMY 250MCG INJECTION 0.5 ML may include: headache, bone pain, muscle aches, joint pain, fatigue, nausea, diarrhea, abdominal pain, vomiting, fever, chills, cough, shortness of breath, skin reactions (such as rash, itching, or redness), injection site reactions (pain, bruising, swelling), dizziness, insomnia, and flu-like symptoms. Less common but potentially serious side effects can include: allergic reactions (hives, difficulty breathing, swelling of the face, lips, tongue, or throat), increased risk of blood clots (symptoms may include chest pain, sudden cough, shortness of breath, swelling, warmth, or pain in one leg), splenic rupture (severe abdominal pain, left upper quadrant pain, shoulder pain), myelofibrosis (fatigue, weakness, easy bruising or bleeding), and progression of underlying hematologic malignancies.

Safety Advice for ROMY 250MCG INJECTION 0.5 MLArrow

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Allergies

Allergies

Do not use ROMY 250MCG INJECTION 0.5 ML if you are allergic to it.

Dosage of ROMY 250MCG INJECTION 0.5 MLArrow

  • The recommended dosage of ROMY 250MCG INJECTION 0.5 ML is determined by your physician based on your specific medical condition, weight, kidney function, and response to treatment. It is crucial to adhere strictly to the prescribed dosage and administration schedule. The injection is typically administered subcutaneously (under the skin). Never self-administer ROMY 250MCG INJECTION 0.5 ML without proper training and guidance from a healthcare professional.
  • For patients with Chronic Kidney Disease (CKD) undergoing dialysis, the initial dose is usually 5 mcg/kg body weight, administered intravenously or subcutaneously three times per week until the target hemoglobin level is achieved. Dosage adjustments are made based on hemoglobin levels, typically increasing or decreasing by 25% increments to maintain the desired range. Hemoglobin levels should be monitored regularly, usually once or twice per week, until stable.
  • In patients with CKD not undergoing dialysis, the initial dose is typically 0.45 mcg/kg body weight, administered subcutaneously once weekly. The physician may increase the dose as needed. Dosage adjustments are also based on hemoglobin levels and typically done every four weeks to maintain the desired range. Hemoglobin levels should be monitored regularly, usually every 1-2 weeks, until stable. It's important to note that ROMY is not a substitute for blood transfusion. A diet rich in Iron should be followed. Iron supplements can be prescribed by your doctor if needed.
  • The duration of treatment depends on the underlying condition and the individual's response to therapy. Do not stop taking ROMY 250MCG INJECTION 0.5 ML without consulting your doctor. Discontinuing the medication abruptly can lead to a decrease in red blood cell production and a recurrence of anemia. Always inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with ROMY 250MCG INJECTION 0.5 ML.
  • Take 'ROMY 250MCG INJECTION 0.5 ML' only as per the prescription by your physician only

What if I miss my dose of ROMY 250MCG INJECTION 0.5 ML?Arrow

  • If you miss a dose of ROMY 250MCG INJECTION 0.5 ML, contact your doctor immediately for further instructions. Do not self-administer a double dose to make up for the missed one.

How to store ROMY 250MCG INJECTION 0.5 ML?Arrow

  • Keep ROMY 250MCG INJ 0.5ML away from the reach of children and pets.
  • Store ROMY 250MCG INJ 0.5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of ROMY 250MCG INJECTION 0.5 MLArrow

  • ROMY 250MCG INJECTION 0.5 ML offers a crucial therapeutic intervention for individuals grappling with thrombocytopenia, a condition characterized by abnormally low platelet counts. Platelets are essential blood components responsible for initiating clot formation, thereby preventing excessive bleeding. By stimulating the production of platelets, ROMY 250MCG INJECTION 0.5 ML actively mitigates the risk of bleeding episodes, enhancing overall patient safety and well-being.
  • A primary benefit of ROMY 250MCG INJECTION 0.5 ML lies in its ability to reduce the incidence of spontaneous bleeding. In individuals with thrombocytopenia, even minor injuries can lead to prolonged and potentially dangerous bleeding. By elevating platelet counts, this medication helps to fortify the body's natural defenses against bleeding, minimizing the likelihood of such events occurring unexpectedly.
  • Furthermore, ROMY 250MCG INJECTION 0.5 ML plays a vital role in preparing patients for surgical procedures. Adequate platelet counts are imperative to minimize bleeding risks during and after surgery. By optimizing platelet levels prior to surgery, this medication facilitates safer surgical interventions and reduces the need for blood transfusions, thereby improving patient outcomes.
  • Beyond surgical preparation, ROMY 250MCG INJECTION 0.5 ML also aids in managing bleeding associated with medical conditions and treatments. Certain medical conditions, such as autoimmune disorders or infections, can lead to thrombocytopenia. Similarly, certain medical treatments, such as chemotherapy, can also suppress platelet production. By counteracting these effects, ROMY 250MCG INJECTION 0.5 ML helps to alleviate bleeding complications and improve the overall quality of life for affected individuals.
  • The use of ROMY 250MCG INJECTION 0.5 ML can lead to a decreased need for platelet transfusions. Platelet transfusions carry inherent risks, including allergic reactions and transmission of infectious diseases. By stimulating endogenous platelet production, this medication reduces reliance on transfusions, minimizing these risks and streamlining patient care.
  • ROMY 250MCG INJECTION 0.5 ML offers a targeted approach to treating thrombocytopenia. Unlike some other treatments that may have broader effects on the body, this medication specifically targets platelet production, minimizing off-target effects and optimizing therapeutic efficacy. This targeted action translates to a more predictable and manageable treatment experience for patients.
  • Improved quality of life is another significant benefit associated with ROMY 250MCG INJECTION 0.5 ML. By reducing the risk of bleeding and minimizing the need for transfusions, this medication empowers individuals with thrombocytopenia to lead more active and fulfilling lives. Patients may experience increased energy levels, reduced anxiety about bleeding, and greater overall well-being.
  • Finally, ROMY 250MCG INJECTION 0.5 ML is generally well-tolerated. While all medications carry the potential for side effects, ROMY 250MCG INJECTION 0.5 ML has been shown to have a favorable safety profile in clinical trials. This means that most individuals can tolerate the medication without experiencing significant adverse effects, further enhancing its therapeutic value.

How to use ROMY 250MCG INJECTION 0.5 MLArrow

  • ROMY 250MCG INJECTION 0.5 ML is administered subcutaneously, meaning it's injected under the skin. Your healthcare provider will determine the appropriate dosage and frequency based on your specific condition and treatment goals. It is crucial to follow their instructions precisely.
  • Before each injection, inspect the pre-filled syringe for any particulate matter or discoloration. If either is present, do not use the syringe and contact your pharmacist or healthcare provider for a replacement.
  • Choose an injection site on your abdomen, thigh, or upper arm. Rotate injection sites to avoid skin irritation or lipodystrophy (changes in fat tissue under the skin). Avoid areas that are tender, bruised, red, or hardened.
  • Clean the injection site with an alcohol swab and allow it to dry completely. Remove the needle cover from the pre-filled syringe, being careful not to touch the needle.
  • Pinch the skin at the injection site and insert the needle at a 45 to 90-degree angle, depending on the thickness of your skin. Inject the medication slowly and steadily, pushing the plunger all the way down.
  • Once the injection is complete, release the pinched skin and withdraw the needle. Apply gentle pressure to the injection site with a clean cotton ball or gauze pad. Do not rub the area.
  • Dispose of the used syringe and needle in a sharps container immediately after use. Do not recap the needle. Keep the sharps container out of reach of children and pets.
  • If you miss a dose of ROMY 250MCG INJECTION 0.5 ML, contact your healthcare provider for instructions. Do not double the dose to catch up.
  • Store ROMY 250MCG INJECTION 0.5 ML in the refrigerator, protected from light. Do not freeze. If the medication has been frozen, do not use it.
  • It's important to attend all scheduled appointments with your healthcare provider so they can monitor your progress and adjust your treatment plan as needed. Report any side effects or concerns to your doctor promptly.

Quick Tips for ROMY 250MCG INJECTION 0.5 MLArrow

  • **Administer as Directed:** Always use ROMY 250MCG INJECTION 0.5 ML exactly as prescribed by your doctor. This ensures you receive the correct dosage for optimal effectiveness and minimizes the risk of side effects. Do not alter the dosage or frequency without consulting your healthcare provider.
  • **Understand Potential Side Effects:** Be aware of the possible side effects of ROMY 250MCG INJECTION 0.5 ML. Common side effects may include headache, joint pain, muscle aches, or injection site reactions. If you experience any severe or persistent side effects, contact your doctor immediately.
  • **Monitor Platelet Counts Regularly:** ROMY 250MCG INJECTION 0.5 ML is used to increase platelet counts. Your doctor will likely order regular blood tests to monitor your platelet levels. Attend all scheduled appointments to ensure your treatment is effective and safe. Timely monitoring helps in adjusting the dosage as needed and prevent complications.
  • **Report Any Bleeding or Bruising:** If you notice any unusual bleeding, bruising, or signs of infection while using ROMY 250MCG INJECTION 0.5 ML, inform your doctor right away. These could be signs of complications related to your platelet levels or the medication itself, requiring immediate medical attention.
  • **Store Properly and Dispose Safely:** Store ROMY 250MCG INJECTION 0.5 ML according to the instructions provided by your pharmacist or healthcare provider. Keep it out of reach of children and pets. Properly dispose of any unused medication or needles to prevent accidental exposure or misuse. Follow local guidelines for safe disposal.

Food Interactions with ROMY 250MCG INJECTION 0.5 MLArrow

  • There are no known significant food interactions with ROMY 250MCG INJECTION 0.5 ML. It can be administered without regard to food intake. However, it is always best to follow your doctor's instructions regarding diet and other medications while on this treatment.

FAQs

What is Romy 250mcg Injection 0.5 ml?Arrow

Romy 250mcg Injection 0.5 ml is a medication used to treat certain medical conditions. It belongs to a class of drugs known as thrombopoietin receptor agonists.

What is Romy 250mcg Injection 0.5 ml used for?Arrow

It is primarily used to increase platelet counts in patients with chronic immune thrombocytopenic purpura (ITP), a condition associated with an increased risk of bleeding.

How is Romy 250mcg Injection 0.5 ml administered?Arrow

It is administered as a subcutaneous (under the skin) injection by a healthcare professional.

What are the common side effects of Romy 250mcg Injection 0.5 ml?Arrow

Common side effects may include headache, joint pain, dizziness, and injection site reactions.

What if I miss a dose of Romy 250mcg Injection 0.5 ml?Arrow

If you miss a dose, contact your healthcare provider as soon as possible so they can advise you on what to do next.

Can Romy 250mcg Injection 0.5 ml interact with other medications?Arrow

Yes, Romy 250mcg Injection 0.5 ml can interact with other medications. Inform your healthcare provider about all the medications, vitamins, and herbal supplements you are taking.

How should Romy 250mcg Injection 0.5 ml be stored?Arrow

Romy 250mcg Injection 0.5 ml should be stored in the refrigerator. Do not freeze it.

Is Romy 250mcg Injection 0.5 ml safe during pregnancy?Arrow

There is limited data on the use of Romy 250mcg Injection 0.5 ml during pregnancy. Talk to your doctor if you are pregnant or planning to become pregnant.

Is Romy 250mcg Injection 0.5 ml safe during breastfeeding?Arrow

It is not known whether Romy 250mcg Injection 0.5 ml passes into breast milk. Consult your doctor before breastfeeding.

What if I am allergic to Romy 250mcg Injection 0.5 ml?Arrow

If you are allergic to Romy 250mcg Injection 0.5 ml, you should not use it. Symptoms of an allergic reaction may include rash, itching, swelling, dizziness, and difficulty breathing.

Is Romy 250mcg Injection 0.5 ml safe for children?Arrow

The safety and effectiveness of Romy 250mcg Injection 0.5 ml have not been established in children.

Can Romy 250mcg Injection 0.5 ml cause cancer?Arrow

There is no known association between Romy 250mcg Injection 0.5 ml and cancer.

Can I drink alcohol while taking Romy 250mcg Injection 0.5 ml?Arrow

It is not recommended to drink alcohol while taking Romy 250mcg Injection 0.5 ml, as it may increase the risk of side effects.

How long does the effect of Romy 250mcg Injection 0.5 ml last?Arrow

The effect of Romy 250mcg Injection 0.5 ml varies from person to person.

Is Romy 250mcg Injection 0.5 ml a steroid?Arrow

No, Romy 250mcg Injection 0.5 ml is not a steroid. It is a thrombopoietin receptor agonist.

References

Book Icon

ROMIPLOSTIM - Full Prescribing Information - Nplate (romiplostim) for Injection - This is the full prescribing information from the FDA, which includes details about the drug's chemical structure, mechanism of action, pharmacokinetics, and clinical trial data.

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Nplate - European Medicines Agency (EMA) - This is the European Medicines Agency's assessment report for Nplate (romiplostim), providing detailed information about its pharmacology, efficacy, and safety.

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Romiplostim in adult patients with immune thrombocytopenia: results of two randomised, placebo-controlled trials - This is a research article published in The Lancet, detailing the results of clinical trials evaluating the efficacy and safety of romiplostim in adult patients with immune thrombocytopenia (ITP).

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Romiplostim: Drug Information - UpToDate - This is a drug information monograph providing a comprehensive overview of romiplostim, including its uses, dosage, administration, precautions, and adverse effects. Requires subscription.

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Romiplostim - DrugBank Online - This entry in the DrugBank database provides detailed chemical and pharmacological information about romiplostim, including its structure, mechanism of action, and interactions.

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Book Icon

Nplate (Romiplostim) Drug Information: Description, User Reviews, Drug Interactions, Dosage & Side Effects - RxList - This is a consumer-oriented drug information resource providing details about Nplate (romiplostim), including its uses, dosage, side effects, and interactions.

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Marketer / Manufacturer Details

INTAS PHARMACEUTICALS LIMITED

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India

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ROMY 250MCG INJECTION 0.5 ML

ROMY 250MCG INJECTION 0.5 ML

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