ROSUKEM FL 5MG TABLET 10'S
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ROSUKEM FL 5MG TABLET 10'S
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ROSUKEM FL 5MG TABLET 10'S

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ROSUKEM FL 5MG TABLET 10'S

By ALKEM LABORATORIES LIMITED

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70

₹59.5

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About ROSUKEM FL 5MG TABLET 10'S

  • ROSUKEM FL 5MG TABLET is a combination medication containing Rosuvastatin and Fenofibrate. It is primarily used to manage dyslipidemia, a condition characterized by abnormal levels of lipids (fats) in the blood. This includes high levels of LDL-cholesterol (bad cholesterol) and triglycerides, as well as low levels of HDL-cholesterol (good cholesterol). By targeting multiple lipid parameters, ROSUKEM FL 5MG TABLET helps reduce the risk of cardiovascular diseases such as heart attack and stroke.
  • Rosuvastatin, a statin, works by inhibiting an enzyme called HMG-CoA reductase in the liver. This enzyme is crucial for the production of cholesterol. By blocking this enzyme, Rosuvastatin reduces the amount of cholesterol produced by the liver, leading to lower levels of LDL-cholesterol in the bloodstream. Additionally, it can modestly increase HDL-cholesterol levels.
  • Fenofibrate belongs to a class of medications called fibrates. It works by activating a protein called PPARα (peroxisome proliferator-activated receptor alpha). Activation of PPARα leads to increased breakdown of triglycerides and increased production of HDL-cholesterol. Fenofibrate is particularly effective at lowering triglyceride levels.
  • ROSUKEM FL 5MG TABLET is usually taken once daily, with or without food. The dosage is determined by a healthcare professional based on individual lipid levels and response to treatment. It is important to follow the prescribed dosage and schedule. Regular monitoring of lipid levels and liver function is recommended during treatment with ROSUKEM FL 5MG TABLET.Lifestyle modifications such as a healthy diet, regular exercise, and weight management are important adjuncts to medication in managing dyslipidemia.

Uses of ROSUKEM FL 5MG TABLET 10'S

  • Treatment of High cholesterol
  • Prevention of Heart attack and stroke
  • Treatment of Mixed Dyslipidemia
  • Treatment of Homozygous Familial Hypercholesterolemia
  • Slowing the progression of atherosclerosis

How ROSUKEM FL 5MG TABLET 10'S Works

  • ROSUKEM FL 5MG TABLET 10'S is a combination medication designed to manage lipid (fat) levels in the blood, specifically targeting cholesterol. It combines two active ingredients: Rosuvastatin and Fenofibrate, each working through different mechanisms to achieve a comprehensive lipid-lowering effect.
  • Rosuvastatin belongs to a class of drugs called statins, or HMG-CoA reductase inhibitors. Its primary function is to inhibit an enzyme called HMG-CoA reductase, which is crucial in the body's synthesis of cholesterol. By blocking this enzyme, Rosuvastatin reduces the production of cholesterol in the liver. This leads to a decrease in the amount of LDL-cholesterol (low-density lipoprotein), often referred to as 'bad' cholesterol, in the bloodstream. Lowering LDL-cholesterol is vital in preventing the buildup of plaque in the arteries, a process known as atherosclerosis.
  • In addition to lowering LDL-cholesterol, Rosuvastatin can also modestly increase HDL-cholesterol (high-density lipoprotein), known as 'good' cholesterol. HDL-cholesterol helps remove LDL-cholesterol from the arteries, further contributing to a healthier lipid profile. Furthermore, Rosuvastatin can also reduce triglyceride levels, another type of fat in the blood, although its effect on triglycerides is generally less pronounced than that of Fenofibrate.
  • Fenofibrate belongs to a class of drugs called fibrates. Fenofibrate primarily works by activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). PPARα is found in various tissues, including the liver and muscle. When activated, PPARα increases the breakdown of triglycerides and increases the production of HDL-cholesterol. This is achieved by increasing the expression of lipoprotein lipase, an enzyme that breaks down triglycerides in the blood.
  • By activating PPARα, Fenofibrate helps to lower triglyceride levels significantly. Elevated triglyceride levels are associated with an increased risk of cardiovascular disease, especially in individuals with low HDL-cholesterol or diabetes. Fenofibrate also has a modest effect on reducing LDL-cholesterol, but its primary benefit lies in its ability to raise HDL-cholesterol and lower triglycerides.
  • The combination of Rosuvastatin and Fenofibrate in ROSUKEM FL 5MG TABLET 10'S provides a synergistic effect on lipid management. Rosuvastatin primarily targets LDL-cholesterol, while Fenofibrate primarily targets triglycerides and increases HDL-cholesterol. This dual-action approach is particularly beneficial for individuals who have mixed dyslipidemia, characterized by high LDL-cholesterol, high triglycerides, and low HDL-cholesterol.
  • Ultimately, ROSUKEM FL 5MG TABLET 10'S works to reduce the risk of cardiovascular events such as heart attack and stroke by improving the overall lipid profile. Lowering LDL-cholesterol reduces the formation of plaques in the arteries, while lowering triglycerides and raising HDL-cholesterol further protects the cardiovascular system. It is crucial to use this medication in conjunction with lifestyle modifications, such as a healthy diet and regular exercise, to maximize its benefits.

Side Effects of ROSUKEM FL 5MG TABLET 10'SArrow

Common side effects of Rosukem FL 5mg Tablet may include: Headache, Muscle pain, Weakness, Nausea, Abdominal pain, Constipation, Diarrhea, Flatulence. Uncommon side effects may include: Skin rash, Itching, Hives, Increased liver enzymes, Muscle disorders (myopathy, rhabdomyolysis), Memory loss, Confusion, Depression, Difficulty sleeping (insomnia), Dizziness, Tingling/numbness, Pancreatitis, Peripheral neuropathy, Erectile dysfunction, Gynecomastia. Rare side effects may include: Severe allergic reactions (anaphylaxis), Hepatitis, Jaundice, Muscle rupture, Immune-mediated necrotizing myopathy. Very rare side effects may include: Hematuria.

Safety Advice for ROSUKEM FL 5MG TABLET 10'SArrow

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Allergies

Allergies

Do not use ROSUKEM FL 5MG TABLET 10'S if you are allergic to it.

Dosage of ROSUKEM FL 5MG TABLET 10'SArrow

  • The recommended dosage of ROSUKEM FL 5MG TABLET 10'S varies depending on individual patient needs and should be determined by your healthcare provider. Typically, the starting dose is 5mg once daily. Your doctor may adjust the dosage based on your cholesterol levels, kidney function, and response to the medication. The maximum daily dose is usually 20mg, but in some cases, a higher dose of 40mg may be prescribed under close medical supervision.
  • It is crucial to follow your doctor's instructions precisely regarding the dosage and timing of ROSUKEM FL 5MG TABLET 10'S. Do not increase or decrease the dose without consulting your doctor. The tablet should be swallowed whole with a glass of water, with or without food. It is recommended to take ROSUKEM FL 5MG TABLET 10'S at the same time each day to maintain consistent drug levels in your body.
  • If you miss a dose of ROSUKEM FL 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Regular monitoring of your cholesterol levels and kidney function is important while taking ROSUKEM FL 5MG TABLET 10'S to ensure the medication is effective and safe for you. Take 'ROSUKEM FL 5MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of ROSUKEM FL 5MG TABLET 10'S?Arrow

  • If you miss a dose of ROSUKEM FL 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store ROSUKEM FL 5MG TABLET 10'S?Arrow

  • Keep ROSUKEM FL 5MG TAB 1X10 away from the reach of children and pets.
  • Store ROSUKEM FL 5MG TAB 1X10 at room temperature.

Benefits of ROSUKEM FL 5MG TABLET 10'SArrow

  • ROSUKEM FL 5MG TABLET 10'S offers a dual-action approach to managing cholesterol and cardiovascular health, combining the benefits of rosuvastatin and fenofibrate into a single convenient tablet. Rosuvastatin, a powerful statin, primarily works by inhibiting the enzyme HMG-CoA reductase, which is crucial in the liver's production of cholesterol. By blocking this enzyme, rosuvastatin effectively reduces the levels of LDL-cholesterol (bad cholesterol) in the bloodstream. Lowering LDL-cholesterol is vital because high levels contribute to the formation of plaque in the arteries, a condition known as atherosclerosis. This plaque buildup narrows the arteries, restricting blood flow and increasing the risk of heart attacks, strokes, and other cardiovascular complications.
  • Fenofibrate, on the other hand, belongs to a class of drugs called fibrates. It primarily works by activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). Activation of PPARα leads to increased breakdown of triglycerides, another type of fat in the blood, and also helps to increase levels of HDL-cholesterol (good cholesterol). High triglycerides and low HDL-cholesterol are often associated with an increased risk of heart disease, particularly in individuals with metabolic syndrome or type 2 diabetes. Thus, fenofibrate complements rosuvastatin by addressing these additional lipid-related risk factors.
  • The combined action of rosuvastatin and fenofibrate in ROSUKEM FL 5MG TABLET 10'S provides a comprehensive approach to lipid management. This is particularly beneficial for individuals with mixed dyslipidemia, a condition characterized by elevated LDL-cholesterol, elevated triglycerides, and low HDL-cholesterol. By targeting all three lipid parameters, ROSUKEM FL 5MG TABLET 10'S offers a more complete solution compared to statin monotherapy alone. This comprehensive approach can lead to a greater reduction in cardiovascular risk.
  • Beyond its direct effects on lipid levels, ROSUKEM FL 5MG TABLET 10'S may also offer additional benefits for cardiovascular health. Rosuvastatin has been shown to have anti-inflammatory properties, which can help to stabilize plaques in the arteries and reduce the risk of plaque rupture, a major cause of heart attacks and strokes. Fenofibrate may also improve endothelial function, the health of the inner lining of blood vessels, which is crucial for maintaining healthy blood flow. These additional benefits contribute to the overall cardioprotective effects of the medication.
  • ROSUKEM FL 5MG TABLET 10'S is typically prescribed as part of a broader strategy to reduce cardiovascular risk. This strategy often includes lifestyle modifications such as adopting a heart-healthy diet, engaging in regular physical activity, maintaining a healthy weight, and quitting smoking. When combined with these lifestyle changes, ROSUKEM FL 5MG TABLET 10'S can significantly reduce the risk of heart attacks, strokes, and other cardiovascular events, leading to improved long-term health and well-being. Always take ROSUKEM FL 5MG TABLET 10'S as prescribed by your healthcare provider, and follow their recommendations for monitoring your cholesterol levels and overall health.

How to use ROSUKEM FL 5MG TABLET 10'SArrow

  • ROSUKEM FL 5MG TABLET 10'S is a combination medication containing Rosuvastatin and Fenofibrate, primarily used to manage dyslipidemia (abnormal lipid levels in the blood). To maximize its effectiveness and safety, adhere to the following guidelines:
  • 1. **Dosage and Timing:** Always take ROSUKEM FL 5MG TABLET 10'S exactly as prescribed by your doctor. The usual dose is one tablet daily. It's generally recommended to take this medication at the same time each day to maintain consistent blood levels. You can take it with or without food, but consistency is key.
  • 2. **Administration:** Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed in your body.
  • 3. **Dietary Considerations:** This medicine works best when combined with a healthy diet low in saturated fat, trans fat, and cholesterol. Follow any dietary recommendations provided by your doctor or a registered dietitian. A heart-healthy diet can significantly enhance the benefits of ROSUKEM FL 5MG TABLET 10'S.
  • 4. **Lifestyle Modifications:** Alongside medication and diet, incorporate regular physical activity into your routine. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Regular exercise helps improve cholesterol levels and overall cardiovascular health. Avoid smoking and limit alcohol consumption, as these can negatively impact your lipid profile.
  • 5. **Regular Monitoring:** Your doctor will likely schedule regular blood tests to monitor your lipid levels and liver function while you are taking ROSUKEM FL 5MG TABLET 10'S. Attend all scheduled appointments and inform your doctor of any side effects or unusual symptoms you experience.
  • 6. **Missed Dose:** If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • 7. **Storage:** Store ROSUKEM FL 5MG TABLET 10'S at room temperature, away from heat, light, and moisture. Keep out of reach of children and pets.
  • 8. **Precautions:** Inform your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Certain medications can interact with ROSUKEM FL 5MG TABLET 10'S. Also, tell your doctor if you have any pre-existing medical conditions, especially liver or kidney disease.
  • 9. **Duration:** Continue taking ROSUKEM FL 5MG TABLET 10'S for as long as your doctor prescribes it. Do not stop taking the medication on your own, even if you feel better, as it may take time to see the full benefits. Discontinuing the medication without your doctor's advice can lead to a rebound in cholesterol levels.

Quick Tips for ROSUKEM FL 5MG TABLET 10'SArrow

  • Take ROSUKEM FL 5MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once daily, with or without food, at the same time each day to maintain consistent levels in your body. Consistency is key for optimal effectiveness.
  • ROSUKEM FL 5MG TABLET 10'S contains rosuvastatin and fenofibrate, which work together to lower bad cholesterol (LDL) and triglycerides while raising good cholesterol (HDL). It's essential to follow a heart-healthy lifestyle, including a balanced diet, regular exercise, and avoiding smoking, to maximize the benefits of this medication. Lifestyle modifications can significantly improve your overall cardiovascular health.
  • Before starting ROSUKEM FL 5MG TABLET 10'S, inform your doctor about any pre-existing medical conditions, especially liver or kidney problems, muscle disorders, or thyroid issues. Also, disclose all other medications, supplements, and herbal products you are taking, as they may interact with ROSUKEM FL. This information helps your doctor assess the safety and suitability of the medication for you.
  • Be aware of potential side effects associated with ROSUKEM FL 5MG TABLET 10'S. Common side effects may include muscle pain or weakness, digestive issues, and headache. If you experience severe muscle pain, tenderness, or weakness, especially if accompanied by fever or fatigue, seek immediate medical attention, as it could be a sign of a rare but serious condition called rhabdomyolysis. Contact your doctor if you notice any other concerning symptoms.
  • Regular monitoring of your cholesterol levels and liver function is crucial while taking ROSUKEM FL 5MG TABLET 10'S. Your doctor will schedule periodic blood tests to assess the medication's effectiveness and check for any potential liver-related issues. Adhering to these monitoring appointments is vital for ensuring the safe and effective use of this medication. If you are planning for any surgery or have any dental treatment, inform your doctor about the medicine you are taking.

Food Interactions with ROSUKEM FL 5MG TABLET 10'SArrow

  • ROSUKEM FL 5MG TABLET 10'S does not typically have significant interactions with food. It can be taken with or without food. However, it is advisable to maintain a consistent dietary pattern while taking this medication.

FAQs

What is Rosukem FL 5mg Tablet 10's?Arrow

Rosukem FL 5mg Tablet 10's is a combination of two medicines: Rosuvastatin and Fenofibrate. It is primarily used to lower cholesterol and triglyceride levels.

What is Rosukem FL 5mg Tablet 10's used for?Arrow

This medicine helps to lower high cholesterol and triglyceride levels, reducing the risk of heart diseases.

What are the common side effects of Rosukem FL 5mg Tablet 10's?Arrow

Common side effects may include nausea, abdominal pain, constipation, headache, and muscle pain.

Can Rosukem FL 5mg Tablet 10's cause muscle pain?Arrow

Yes, some patients may experience muscle pain or weakness. Contact your doctor immediately if you experience severe muscle pain.

How to store Rosukem FL 5mg Tablet 10's?Arrow

Store it at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Can Rosukem FL 5mg Tablet 10's be taken with or without food?Arrow

It can be taken with or without food, but it's important to take it at the same time each day.

Is Rosukem FL 5mg Tablet 10's safe during pregnancy?Arrow

This medicine is not safe during pregnancy. Inform your doctor if you are pregnant or planning to become pregnant.

What happens if I miss a dose of Rosukem FL 5mg Tablet 10's?Arrow

If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule.

Is it safe to drink alcohol while taking Rosukem FL 5mg Tablet 10's?Arrow

It is best to limit alcohol consumption while taking Rosukem FL 5mg Tablet 10's, as it may increase the risk of side effects.

Can Rosukem FL 5mg Tablet 10's interact with other medications?Arrow

Yes, Rosukem FL 5mg Tablet 10's can interact with certain other medications. Tell your doctor about all the medicines you are taking.

What are the other brands of Rosuvastatin and Fenofibrate?Arrow

Rosuvastatin and Fenofibrate are available under various brand names. Ask your doctor about specific alternatives.

What dietary precautions should I take while taking Rosukem FL 5mg Tablet 10's?Arrow

Follow a balanced diet that is low in fat and cholesterol. Exercise regularly and maintain a healthy weight.

Is Rosukem FL 5mg Tablet 10's safe for long-term use?Arrow

Rosukem FL 5mg Tablet 10's can be used for the duration prescribed by your doctor. Regular check-ups are important.

What happens if I overdose on Rosukem FL 5mg Tablet 10's?Arrow

If you suspect you have taken an overdose of this medicine, seek immediate medical attention.

How does Rosukem FL 5mg Tablet 10's work?Arrow

Rosuvastatin reduces the production of cholesterol, while Fenofibrate breaks down triglycerides, leading to lower fat levels in the blood.

References

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DrugBank: Rosuvastatin and Ezetimibe Combination. This entry provides detailed chemical and pharmacological information about the combination drug.

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PubMed Central: Efficacy and safety of rosuvastatin/ezetimibe fixed-dose combination therapy compared with rosuvastatin monotherapy in patients with hypercholesterolemia: A systematic review and meta-analysis. This study analyzes the clinical efficacy and safety of the rosuvastatin/ezetimibe combination.

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European Medicines Agency (EMA): Rosuvastatin. This provides the European regulatory view on rosuvastatin.

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FDA: CRESTOR (rosuvastatin calcium) prescribing information. This is the official prescribing information for rosuvastatin from the FDA.

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DrugBank: Rosuvastatin. This entry provides detailed chemical and pharmacological information about rosuvastatin.

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DrugBank: Ezetimibe. This entry provides detailed chemical and pharmacological information about ezetimibe.

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PubMed Central: Ezetimibe: a review of its mechanism of action, clinical efficacy and safety. This review article covers the mechanism of action, efficacy, and safety of ezetimibe.

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ALKEM LABORATORIES LIMITED

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India

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