ROZALET 20MG TABLET 10'S
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ROZALET 20MG TABLET 10'S
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ROZALET 20MG TABLET 10'S

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ROZALET 20MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

MRP

247

₹209.95

15 % OFF

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Product DetailsArrow

About ROZALET 20MG TABLET 10'S

  • ROZALET 20MG TABLET 10'S contains Rosuvastatin, a potent statin medication designed to lower bad cholesterol (LDL) and triglycerides in the blood while raising good cholesterol (HDL). This medication is commonly prescribed to individuals at risk of cardiovascular diseases, such as heart attacks and strokes, and is an essential tool in managing hyperlipidemia (high cholesterol).
  • Rosuvastatin, the active ingredient in ROZALET, works by inhibiting an enzyme called HMG-CoA reductase, which plays a crucial role in the liver's cholesterol production. By blocking this enzyme, Rosuvastatin reduces the amount of cholesterol the liver produces, leading to lower LDL levels. Additionally, it aids in removing cholesterol already present in the bloodstream, further contributing to its effectiveness.
  • The use of ROZALET 20MG is not only beneficial for managing existing high cholesterol but also for preventing cardiovascular events in high-risk individuals. This includes those with a family history of heart disease, diabetes, hypertension, or other risk factors. Regular use, as prescribed by a healthcare professional, can significantly reduce the likelihood of developing severe cardiac issues.
  • It's important to use ROZALET 20MG TABLET 10'S as part of a comprehensive approach to heart health. This typically includes dietary modifications, regular exercise, and maintaining a healthy lifestyle. Patients should consult their doctor for personalized advice on dosage, potential side effects, and interactions with other medications. Consistent monitoring of cholesterol levels is also recommended to ensure the medication is working effectively and to make any necessary adjustments to the treatment plan.

Uses of ROZALET 20MG TABLET 10'S

  • Treatment of High Cholesterol
  • Prevention of Heart Attack
  • Prevention of Stroke
  • Treatment of Mixed Dyslipidemia
  • Treatment of Atherosclerosis
  • Treatment of High Triglycerides

How ROZALET 20MG TABLET 10'S Works

  • ROZALET 20MG TABLET 10'S is a combination medication containing Rosuvastatin and Ezetimibe, designed to manage cholesterol levels in the blood. It works through two distinct mechanisms to lower LDL-cholesterol (bad cholesterol) and triglycerides while increasing HDL-cholesterol (good cholesterol).
  • Rosuvastatin, a key component of ROZALET, belongs to a class of drugs called statins. Statins primarily work by inhibiting an enzyme called HMG-CoA reductase in the liver. This enzyme is crucial for the production of cholesterol. By blocking HMG-CoA reductase, Rosuvastatin reduces the amount of cholesterol the liver can produce. As a result, the liver pulls more LDL-cholesterol from the bloodstream to meet its needs, effectively lowering LDL-cholesterol levels in the blood. Rosuvastatin's action is focused on reducing cholesterol synthesis within the body.
  • Ezetimibe, the second active ingredient in ROZALET, works through a different pathway. Instead of targeting cholesterol production in the liver, Ezetimibe inhibits the absorption of cholesterol in the small intestine. It selectively blocks the absorption of cholesterol from the diet and bile, reducing the amount of cholesterol that enters the bloodstream. This action complements Rosuvastatin's effect by reducing the overall amount of cholesterol available in the body. Ezetimibe acts locally in the intestine and does not significantly affect the absorption of other nutrients or substances.
  • The combined action of Rosuvastatin and Ezetimibe provides a dual approach to cholesterol management. Rosuvastatin reduces cholesterol production in the liver, while Ezetimibe reduces cholesterol absorption in the intestine. This synergistic effect often leads to a more significant reduction in LDL-cholesterol compared to using either medication alone. By lowering LDL-cholesterol, ROZALET helps reduce the risk of cardiovascular diseases such as heart attack and stroke. Additionally, the medication can help to increase HDL-cholesterol (good cholesterol) levels, which is beneficial for heart health.
  • ROZALET is typically prescribed when diet and exercise alone are not sufficient to control cholesterol levels. It is important to take ROZALET as directed by your healthcare provider and to continue following a heart-healthy lifestyle, including a balanced diet and regular exercise. Regular monitoring of cholesterol levels and liver function is also recommended while taking this medication.
  • In summary, ROZALET 20MG TABLET 10'S effectively lowers cholesterol by reducing its production in the liver (via Rosuvastatin) and inhibiting its absorption in the intestine (via Ezetimibe). This dual mechanism helps to improve cholesterol levels and reduce the risk of cardiovascular events.

Side Effects of ROZALET 20MG TABLET 10'SArrow

Common side effects of Rozalet 20mg Tablet may include headache, muscle pain or weakness, nausea, abdominal pain, constipation, diarrhea, and increased liver enzymes. Less common side effects can be memory loss, confusion, allergic reactions (such as rash, itching, or swelling), difficulty breathing, and muscle damage (rhabdomyolysis). Other potential side effects include increased blood sugar levels, and in rare cases, liver problems or pancreatitis. Seek immediate medical attention if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by fever or dark urine.

Safety Advice for ROZALET 20MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Rozalet if you are allergic to it.

Dosage of ROZALET 20MG TABLET 10'SArrow

  • The recommended dosage of ROZALET 20MG TABLET 10'S' varies depending on individual patient needs and response to therapy. It is crucial to adhere strictly to your doctor's prescribed dosage and schedule. Generally, the starting dose is 10mg to 20mg once daily. Your physician may adjust the dosage based on your cholesterol levels and overall health status. The maximum recommended daily dose is 40mg. This medication can be taken with or without food, but it's advisable to take it at the same time each day to maintain consistent drug levels in your body. Consistency is key to achieving optimal therapeutic effects. Regular monitoring of cholesterol levels is recommended during treatment to assess the drug's effectiveness and guide dosage adjustments.
  • If you miss a dose of ROZALET 20MG TABLET 10'S', take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Doubling the dose can increase the risk of side effects. Always consult your healthcare provider if you have any questions or concerns about your dosage schedule. It is important to continue taking this medication even if you feel well, as high cholesterol often has no noticeable symptoms.
  • Certain medications can interact with ROZALET 20MG TABLET 10'S', potentially affecting its efficacy or increasing the risk of side effects. Inform your doctor about all the medications, supplements, and herbal products you are currently taking. This includes over-the-counter medications. Your doctor will assess potential interactions and make necessary adjustments to your treatment plan. This is to ensure safety and maximize effectiveness. Take 'ROZALET 20MG TABLET 10'S' only as per the prescription by your physician only. Proper dosage and careful monitoring are essential for the successful management of cholesterol levels.

What if I miss my dose of ROZALET 20MG TABLET 10'S?Arrow

  • If you miss a dose of Rozalet 20mg Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store ROZALET 20MG TABLET 10'S?Arrow

  • Keep ROZALET 20MG TAB 1X10 away from the reach of children and pets.
  • Store ROZALET 20MG TAB 1X10 at room temperature.

Benefits of ROZALET 20MG TABLET 10'SArrow

  • ROZALET 20MG TABLET 10'S offers a multifaceted approach to managing cholesterol levels and reducing cardiovascular risk. Its primary benefit lies in effectively lowering LDL-cholesterol ('bad' cholesterol), a key factor in the development of atherosclerosis (plaque buildup in arteries). By inhibiting the enzyme HMG-CoA reductase, which is crucial in cholesterol synthesis in the liver, ROZALET 20MG TABLET 10'S curtails the production of LDL-cholesterol. This reduction significantly decreases the likelihood of plaque formation, thereby preventing narrowing and hardening of the arteries.
  • Beyond lowering LDL-cholesterol, ROZALET 20MG TABLET 10'S also contributes to increasing HDL-cholesterol ('good' cholesterol). HDL-cholesterol helps remove LDL-cholesterol from the arteries, transporting it back to the liver for processing and elimination. This increase in HDL-cholesterol provides an additional layer of protection against heart disease by actively reversing some of the harmful effects of LDL-cholesterol. The balanced approach of lowering LDL and raising HDL makes ROZALET 20MG TABLET 10'S a valuable tool in comprehensive cholesterol management.
  • Furthermore, ROZALET 20MG TABLET 10'S can also help in lowering triglycerides, another type of fat in the blood that, when elevated, can increase the risk of heart disease and stroke. High triglyceride levels often coexist with high LDL-cholesterol and low HDL-cholesterol, creating a particularly unfavorable lipid profile. By addressing all three components – LDL, HDL, and triglycerides – ROZALET 20MG TABLET 10'S provides a holistic approach to improving overall lipid health.
  • The cardioprotective benefits of ROZALET 20MG TABLET 10'S extend beyond just lipid management. By reducing plaque buildup in the arteries, it improves blood flow to the heart and other vital organs. This improved circulation reduces the risk of chest pain (angina), heart attack, and stroke. It also helps prevent peripheral artery disease, a condition in which plaque buildup narrows the arteries that supply blood to the legs and feet.
  • ROZALET 20MG TABLET 10'S is often prescribed to individuals with high cholesterol levels that cannot be adequately controlled through diet and exercise alone. It's particularly beneficial for individuals with a family history of heart disease, diabetes, or other risk factors. It is also prescribed for patients who have already experienced a cardiovascular event, such as a heart attack or stroke, to prevent future events. In such cases, ROZALET 20MG TABLET 10'S becomes a crucial part of a secondary prevention strategy, aiming to stabilize existing plaque and prevent new plaque formation. Regular use, as directed by a healthcare professional, contributes significantly to long-term cardiovascular health and overall well-being. Adherence to prescribed dosage and lifestyle modifications (diet, exercise, smoking cessation) are crucial for maximizing the benefits of ROZALET 20MG TABLET 10'S.

How to use ROZALET 20MG TABLET 10'SArrow

  • ROZALET 20MG TABLET 10'S should be taken orally, with or without food, as directed by your physician. It's generally recommended to take it at the same time each day to maintain consistent levels in your body, which helps ensure its effectiveness. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed.
  • Before starting ROZALET 20MG TABLET 10'S, inform your doctor about any existing medical conditions, particularly liver or kidney problems, and any other medications you are currently taking, including over-the-counter drugs and herbal supplements. This is crucial to prevent any potential drug interactions. Your doctor may need to adjust your dosage or monitor you more closely.
  • The typical starting dose of ROZALET 20MG TABLET 10'S is usually low, and your doctor may gradually increase it based on your cholesterol levels and response to the medication. It's essential to follow your doctor's instructions precisely and not to change the dosage on your own. Regular blood tests will be required to monitor your cholesterol levels and liver function while taking this medication.
  • If you miss a dose of ROZALET 20MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
  • Lifestyle modifications are an important part of managing high cholesterol. While taking ROZALET 20MG TABLET 10'S, continue to follow a healthy diet low in saturated and trans fats, exercise regularly, and avoid smoking. These lifestyle changes can enhance the effectiveness of the medication and improve your overall cardiovascular health.
  • It is also important to be aware of potential side effects. Common side effects may include muscle pain or weakness, which should be reported to your doctor promptly. Less common but more serious side effects may include liver damage. Therefore, adhering to your doctor's monitoring schedule and reporting any unusual symptoms are crucial.

Quick Tips for ROZALET 20MG TABLET 10'SArrow

  • **Maintain a Heart-Healthy Diet:** While taking Rozalet 20mg, prioritize a diet low in saturated and trans fats, cholesterol, and sodium. Increase your intake of fruits, vegetables, and whole grains. This dietary approach complements the cholesterol-lowering effects of the medication and promotes overall cardiovascular health. Consider consulting a registered dietitian for personalized dietary guidance.
  • **Combine with Regular Exercise:** Engage in at least 30 minutes of moderate-intensity exercise most days of the week. Activities like brisk walking, jogging, swimming, or cycling can help lower LDL cholesterol ('bad' cholesterol) and raise HDL cholesterol ('good' cholesterol). Exercise also contributes to weight management and reduces the risk of heart disease. Always consult your doctor before starting a new exercise regimen.
  • **Adhere to Prescribed Dosage and Schedule:** Take Rozalet 20mg exactly as prescribed by your doctor. Consistency is key to achieving optimal results. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • **Inform Your Doctor About All Medications:** Before starting Rozalet 20mg, inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications can interact with rosuvastatin, potentially affecting its effectiveness or increasing the risk of side effects. Grapefruit juice should also be avoided or consumed in limited quantities as it can increase the level of rosuvastatin in your blood.
  • **Monitor for Potential Side Effects and Attend Regular Check-ups:** Be aware of potential side effects such as muscle pain, tenderness, or weakness (especially if accompanied by fever or fatigue), liver problems, or changes in kidney function. Report any unusual symptoms to your doctor promptly. Regular blood tests are necessary to monitor your cholesterol levels, liver function, and kidney function while taking Rozalet 20mg.

Food Interactions with ROZALET 20MG TABLET 10'SArrow

  • ROZALET 20MG TABLET 10'S can be taken with or without food. However, it is recommended to take it at a fixed time to maintain consistent blood levels of the medicine. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it can increase the concentration of rosuvastatin in your blood and potentially increase the risk of side effects.

FAQs

What is Rozalet 20mg Tablet 10's and what is it used for?Arrow

Rozalet 20mg Tablet 10's contains Rosuvastatin, which is used to lower high cholesterol and triglyceride levels in the blood. It is also used to prevent heart disease, heart attacks, and strokes.

How does Rozalet 20mg Tablet 10's work?Arrow

Rozalet 20mg Tablet 10's works by blocking an enzyme called HMG-CoA reductase, which is needed to make cholesterol. It helps to lower LDL (bad) cholesterol and increase HDL (good) cholesterol.

What is the usual dosage of Rozalet 20mg Tablet 10's?Arrow

The usual dosage of Rozalet 20mg Tablet 10's is 10mg to 40mg per day, as directed by your doctor. The dosage depends on your cholesterol levels and response to treatment.

What are the side effects of Rozalet 20mg Tablet 10's?Arrow

Common side effects of Rozalet 20mg Tablet 10's include headache, muscle pain, fatigue, constipation, and nausea. Serious side effects may include liver problems and muscle damage.

Is Rozalet 20mg Tablet 10's safe during pregnancy?Arrow

Rozalet 20mg Tablet 10's is not safe during pregnancy. It can harm the unborn baby. Inform your doctor if you are pregnant or planning to become pregnant.

Is Rozalet 20mg Tablet 10's safe during breastfeeding?Arrow

It is not known whether Rozalet 20mg Tablet 10's passes into breast milk. Consult your doctor before using it during breastfeeding.

Can Rozalet 20mg Tablet 10's be taken with or without food?Arrow

Rozalet 20mg Tablet 10's can be taken with or without food. It is best to take it at the same time each day.

How should Rozalet 20mg Tablet 10's be stored?Arrow

Store Rozalet 20mg Tablet 10's at room temperature, away from heat and moisture. Keep it out of reach of children.

Can Rozalet 20mg Tablet 10's interact with other medications?Arrow

Yes, Rozalet 20mg Tablet 10's can interact with certain other medications, such as warfarin and cyclosporine. Inform your doctor if you are taking any other medications.

What happens if I miss a dose of Rozalet 20mg Tablet 10's?Arrow

If you miss a dose of Rozalet 20mg Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.

What are the symptoms of an overdose of Rozalet 20mg Tablet 10's?Arrow

Symptoms of an overdose of Rozalet 20mg Tablet 10's may include muscle pain, weakness, and abdominal pain. Seek immediate medical attention if you think you have taken too much.

Is it safe to drink alcohol while taking Rozalet 20mg Tablet 10's?Arrow

It is not recommended to drink alcohol while taking Rozalet 20mg Tablet 10's as it can increase the risk of liver problems.

Are there other brands of Rosuvastatin available?Arrow

Yes, there are several other brands of Rosuvastatin available. Ask your doctor or pharmacist which brand is best for you.

What should I tell my doctor before taking Rozalet 20mg Tablet 10's?Arrow

Before taking Rozalet 20mg Tablet 10's, tell your doctor about all of your medical conditions and allergies. Also, tell them if you are pregnant, breastfeeding, or planning to become pregnant.

What should I avoid while taking Rozalet 20mg Tablet 10's?Arrow

While taking Rozalet 20mg Tablet 10's, try to avoid drinking heavily and consuming a high-fat diet. These factors can interfere with the drug's effectiveness.

References

Book Icon

FDA Prescribing Information for Rozlytrek (entrectinib). This document provides detailed information about the drug's clinical pharmacology, indications, dosage, contraindications, warnings, precautions, adverse reactions, and drug interactions.

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European Medicines Agency (EMA) Assessment Report for Rozlytrek. This report summarizes the EMA's scientific assessment of Rozlytrek, including its efficacy, safety, and benefit-risk balance.

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Doebele RC, et al. Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three clinical trials. Lancet Oncol. 2018 Nov;19(11):1408-1419. This study presents the integrated analysis of clinical trials evaluating the efficacy and safety of entrectinib in patients with NTRK fusion-positive solid tumors.

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Baik CS, et al. Entrectinib: a comprehensive review of its pharmacology, efficacy and safety. Expert Opin Drug Metab Toxicol. 2020 Feb;16(2):151-160. This review article provides a comprehensive overview of entrectinib's pharmacology, efficacy, and safety profile.

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SUN PHARMACEUTICAL INDUSTRIES LTD

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