RYBREVANT 350MG INJECTION
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RYBREVANT 350MG INJECTION
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RYBREVANT 350MG INJECTION

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RYBREVANT 350MG INJECTION

By JANSSEN-CILAG PHARMACEUTICALS

MRP

₹

98500

₹88650

10 % OFF

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Product DetailsArrow

About RYBREVANT 350MG INJECTION

  • RYBREVANT 350MG INJECTION contains the active ingredient Amivantamab. This medicine is a type of targeted therapy used to fight cancer. It belongs to a group of medicines called bispecific antibodies, which are designed to help your body's immune system recognize and attack cancer cells. RYBREVANT 350MG INJECTION is specifically used to treat a type of lung cancer known as non-small cell lung cancer (NSCLC). It is given to patients whose cancer has spread to other parts of the body (metastatic) and has specific changes in a gene called EGFR. This treatment is typically used when surgery is not an option and the cancer has continued to grow or has come back after trying other cancer treatments.
  • You should not receive RYBREVANT 350MG INJECTION if you have a known allergy to amivantamab or any other ingredients in this medicine. Before starting treatment, it's important to tell your doctor if you have ever had inflammation in your lungs (also called pneumonitis or interstitial lung disease) or any other lung problems. During treatment, watch out for signs like sudden trouble breathing, a new or worsening cough, or fever, as these could be symptoms of lung inflammation. If you experience any of these, contact your doctor right away. RYBREVANT 350MG INJECTION is not recommended for use in children or young people under 18 years of age.
  • Make sure to inform your doctor about any existing health conditions, especially if you have or have had kidney problems, liver problems, or lung problems. RYBREVANT 350MG INJECTION is given as an injection into a vein by a healthcare professional. Your doctor or nurse will monitor you closely, especially during the first doses, for any reactions. Common side effects you might experience include skin rash, inflammation around the nails, pain in muscles or bones, feeling short of breath, nausea, feeling tired (fatigue), swelling, sore mouth, cough, constipation, and vomiting. It's important to discuss any side effects you experience with your doctor or nurse, as they can help manage them. This medicine can be harmful to a developing baby. If you are pregnant or planning to become pregnant, tell your doctor. Women who could become pregnant should use effective birth control during treatment and for a period after the last dose, as advised by their doctor. Men whose partners could become pregnant should also use effective contraception.

Uses of RYBREVANT 350MG INJECTION

  • A type of lung cancer called non-small cell lung cancer (NSCLC)

Side Effects of RYBREVANT 350MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Not everyone gets side effects, even though all drugs can cause them. Side effects of RYBREVANT 350MG INJECTION include:

  • Swelling in the face, hands, and feet
  • Inflammation in the nails
  • Constipation
  • Nausea, vomiting
  • Inflamed and sore mouth
  • Musculoskeletal pain
  • Cough
  • Shortness of breath
  • Tiredness
  • Severe rashes in the skin
  • Eye pain and infection
  • Inflammation of the lungs
  • Infusion reactions

Safety Advice for RYBREVANT 350MG INJECTIONArrow

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Pregnancy

UNSAFE

RYBREVANT 350MG INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 3 months after your last dose is necessary.

Dosage of RYBREVANT 350MG INJECTIONArrow

  • RYBREVANT 350MG INJECTION is not a medication you can administer to yourself. It must be given by a trained healthcare professional, such as a doctor or nurse, in a hospital or clinic setting experienced in cancer chemotherapy. This is because administering the infusion requires specific expertise and careful monitoring throughout the process to ensure your safety and the treatment's effectiveness.
  • The medication is delivered directly into your bloodstream through a needle inserted into your vein. This method is known as an intravenous (IV) infusion. The infusion is typically administered slowly over a period of several hours, delivered as a continuous drip. You will usually be seated comfortably during this time, and healthcare staff will closely observe you during and immediately after the infusion to watch for any reactions.
  • Your doctor is solely responsible for determining the precise dose of RYBREVANT 350MG INJECTION you will receive and the frequency of your treatments. This decision is based on several important factors, including the specific type and severity of your condition, your body weight, your overall health status, and how well you tolerate the treatment. It is absolutely essential to strictly adhere to your doctor's prescribed dose and treatment schedule and never attempt to inject this medication yourself.

How to store RYBREVANT 350MG INJECTION?Arrow

  • Keep RYBREVANT 350MG INJ 7ML away from the reach of children and pets.
  • Store RYBREVANT 350MG INJ 7ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of RYBREVANT 350MG INJECTIONArrow

  • RYBREVANT 350MG INJECTION is a special kind of medicine designed to fight certain types of lung cancer. It's what's called a 'targeted therapy,' meaning it doesn't just affect all cells but specifically goes after cancer cells. This medicine is unique because it's a 'bispecific antibody,' which acts a bit like a key designed to fit two different locks on the cancer cells. These 'locks' are two important proteins called EGFR and MET. Cancer cells often have too much of these proteins, which helps them grow and spread. RYBREVANT 350MG INJECTION is made to recognize and attach itself to both EGFR and MET proteins at the same time. By latching onto these specific targets, RYBREVANT helps to block the signals that tell the cancer cells to grow. This action can potentially slow down or even stop the lung cancer from growing further. It may also help to shrink the size of the existing tumors, offering a way to manage the disease and improve patient outcomes.

How to use RYBREVANT 350MG INJECTIONArrow

  • This treatment is always given to you by a qualified doctor or nurse. It is administered in a hospital or clinic setting where staff are trained in cancer therapies. The medication is delivered directly into your vein through a slow drip, known as an intravenous infusion. This infusion typically takes several hours to complete.
  • It is crucial that you never attempt to give this injection to yourself. The dose and how long you receive the treatment will be carefully determined by your doctor. They will consider factors specific to you, such as the type and severity of your condition, your body size, and your overall health. You will need to remain at the clinic or hospital during the entire infusion process to ensure you are monitored properly.

FAQs

What are the infusion reactions that might happen during RYBREVANT 350MG INJECTION infusion?Arrow

Allergic reactions like itching. Swelling in your face or hands, tingling in mouth or throat, chest tightness, difficulty in breathing, fever, chills, cough, sore throat, body aches, unusual bleeding, bruising, or weakness should be informed to your doctor immediately.

How long should I have to take RYBREVANT 350MG INJECTION?Arrow

RYBREVANT 350MG INJECTION is given as a cycle therapy. Your doctor will decide the dose and duration of the therapy based on your disease severity and condition.

How long does RYBREVANT 350MG INJECTION infusion take?Arrow

Your first dose (the infusion on Day 1 and Day 2) can take about 4 to 6 hours. Infusions can get shorter starting on Week 2, and can take about 2 to 4 hours. Your doctor will decide the infusion rate based on your disease condition and other factors.

What are the eye problems that may occur while taking RYBREVANT 350MG INJECTION?Arrow

Eye pain, dry eyes, eye redness, blurred vision, changes in the vision, itchy eyes, excessive tearing, sensitivity to light are the eye problems that may occur with this treatment. Inform your physician if you face any of the symptoms.

Why should I avoid sun exposure during the treatment with RYBREVANT 350MG INJECTION?Arrow

RYBREVANT 350MG INJECTION can cause skin reactions. You should limit your time in the sun during your treatment with this medicine.

Can I take vitamin supplements with RYBREVANT 350MG INJECTION?Arrow

Certain medications may interact with the effectiveness of RYBREVANT 350MG INJECTION including prescription, over-the-counter medicines, vitamin or nutritional supplements and herbal products. Inform your physician about all your medication history.

Does RYBREVANT 350MG INJECTION interact with other medications?Arrow

Certain medications may interact with RYBREVANT 350MG INJECTION, including prescription drugs, over-the-counter medicines, vitamin supplements, nutritional supplements, and herbal products. It's important to inform your doctor about all the medications you are taking.

What precautions should I take while using RYBREVANT 350MG INJECTION?Arrow

To reduce skin problems, limit sun exposure during treatment and for 2 months after. Wear protective clothing and use alcohol-free sunscreen and moisturizers on skin and nails regularly. Contact your doctor or nurse immediately for eye pain or vision problems. Consult your doctor before using contact lenses when you are taking this medicine. Do not breastfeed during the treatment and for 3 months after the last dose. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy.

What is the active ingredient in RYBREVANT 350MG INJECTION?Arrow

The active ingredient in RYBREVANT 350MG INJECTION is AMIVANTAMAB.

What is RYBREVANT 350MG INJECTION used for?Arrow

RYBREVANT 350MG INJECTION is used to treat certain types of cancer.

References

Book Icon

Rybrevant (amivantamab) 50mg/mL concentrate for solution for infusion - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk.

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Book Icon

HIGHLIGHTS OF PRESCRIBING INFORMATION - amivantamab.

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Park K, Haura EB, Leighl NB, Mitchell P, Shu CA, Girard N, et al. Amivantamab in EGFR Exon 20 Insertion–Mutated Non–Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results from the CHRYSALIS Phase I Study. Journal of Clinical Oncology;39(30):JCO.21.00662.

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Good service. Public relations are very good.

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Reviewed on 22-11-2022

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Marketer / Manufacturer Details

JANSSEN-CILAG PHARMACEUTICALS

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RYBREVANT 350MG INJECTION

RYBREVANT 350MG INJECTION

MRP

₹

98500

₹88650

10 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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