SATROGYL O TABLET 10'S

How SATROGYL O TABLET 10'S Works

• SATROGYL O TABLET 10'S is a combination medication formulated to combat bacterial infections, particularly those affecting the gastrointestinal tract and other susceptible areas. It leverages the synergistic action of its two active ingredients: Ornidazole and Ofloxacin. Understanding how each component works individually and in tandem is key to appreciating the effectiveness of SATROGYL O.
• Ofloxacin, a fluoroquinolone antibiotic, exerts its antibacterial effect by interfering with bacterial DNA replication and repair. Specifically, it inhibits two crucial enzymes: DNA gyrase and topoisomerase IV. DNA gyrase is essential for supercoiling bacterial DNA, a process necessary for packaging the lengthy DNA molecule into the confined space of the bacterial cell. Topoisomerase IV, on the other hand, plays a vital role in separating interlinked daughter DNA molecules during cell division. By blocking these enzymes, Ofloxacin prevents bacterial DNA from replicating properly, ultimately leading to bacterial cell death. This mechanism of action makes Ofloxacin effective against a broad spectrum of bacteria, including both Gram-positive and Gram-negative organisms.
• Ornidazole, a nitroimidazole antibiotic, targets anaerobic bacteria and certain protozoa. Its mechanism of action involves the reduction of its nitro group within the anaerobic bacterial cell. This reduction process generates reactive nitro radicals, which are highly toxic to the bacterial DNA. These radicals cause strand breaks and other forms of DNA damage, disrupting the bacterial DNA's structure and function. As a result, the bacteria are unable to replicate or carry out essential cellular processes, leading to their demise. Ornidazole is particularly effective against anaerobic bacteria commonly found in the gut, making it a valuable component in treating gastrointestinal infections.
• The combination of Ofloxacin and Ornidazole in SATROGYL O provides a dual-pronged attack against bacterial infections. Ofloxacin targets a wide range of bacteria by inhibiting DNA replication, while Ornidazole specifically targets anaerobic bacteria through DNA damage via reactive radicals. This synergistic effect broadens the spectrum of antibacterial activity, making SATROGYL O effective against mixed infections involving both aerobic and anaerobic bacteria. The combined action helps to eradicate the infection more effectively and reduces the likelihood of bacterial resistance development. By targeting different bacterial processes, the two drugs complement each other, leading to a more comprehensive and potent antibacterial effect.
• In summary, SATROGYL O TABLET 10'S works by combining the DNA replication inhibition of Ofloxacin with the DNA-damaging effects of Ornidazole. This dual mechanism of action allows it to effectively combat a wide range of bacterial infections, especially those involving both aerobic and anaerobic bacteria, providing a comprehensive approach to infection control.

Common side effects of SATROGYL O TABLET 10'S may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, and skin rash. Uncommon side effects can include constipation, dry mouth, dark urine, neurological problems (like seizures or peripheral neuropathy), allergic reactions (itching, hives, swelling), and changes in liver function tests.Rare side effects may include Stevens-Johnson syndrome and toxic epidermal necrolysis.

• If you miss a dose of SATROGYL O TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep SATROGYL O TAB 1X10 away from the reach of children and pets.
• Store SATROGYL O TAB 1X10 at room temperature.

• Complete the Full Course: Always finish the entire course of SATROGYL O TABLET 10'S as prescribed by your doctor, even if you start feeling better. Stopping early can lead to the infection returning or bacteria becoming resistant to the antibiotic. Consistent adherence ensures the medication works effectively to eliminate the infection and prevent recurrence. Do not share your medication with others, even if they have similar symptoms.
• Take with Food: To minimize stomach upset and enhance absorption, take SATROGYL O TABLET 10'S with food. This helps reduce nausea, vomiting, and other gastrointestinal side effects that can sometimes occur with antibiotics. A small snack or a full meal can both be effective. Taking it at the same time each day with a meal also helps you remember to take your dose.
• Stay Hydrated: Drink plenty of water throughout the day while taking SATROGYL O TABLET 10'S. Adequate hydration supports your body's natural processes and helps flush out the infection. Aim for at least 8 glasses of water daily to stay well-hydrated and support overall health. Staying hydrated can also help alleviate potential side effects like dizziness or headache.
• Avoid Alcohol: It's crucial to avoid alcohol while taking SATROGYL O TABLET 10'S, as alcohol can interact with the medication and worsen side effects. Alcohol may reduce the effectiveness of the antibiotic and exacerbate symptoms like nausea, vomiting, and drowsiness. Combining alcohol and SATROGYL O can also put extra strain on your liver. Wait at least 24-48 hours after finishing the course before consuming alcohol.
• Probiotic Consideration: Since SATROGYL O TABLET 10'S can disrupt the natural balance of bacteria in your gut, consider taking a probiotic supplement or consuming probiotic-rich foods like yogurt. Probiotics can help restore beneficial bacteria and prevent antibiotic-associated diarrhea. Consult your doctor or pharmacist for recommendations on suitable probiotics and timing of intake to maximize effectiveness. Do not take probiotics at the exact same time as the antibiotic, stagger the intake by a few hours.

• SATROGYL O TABLET 10'S can be taken with or without food. However, it is generally recommended to take it after food to avoid stomach upset.
• Avoid consuming alcohol while taking SATROGYL O TABLET 10'S, as it may increase the risk of side effects like nausea, vomiting, and liver damage.