SERETIDE ACCUHALER 50/100 28MD

How SERETIDE ACCUHALER 50/100 28MD Works

• SERETIDE ACCUHALER 50/100 28MD is a combination inhaler containing two active ingredients: fluticasone propionate and salmeterol. These medications work synergistically to manage and prevent symptoms of asthma and chronic obstructive pulmonary disease (COPD). Fluticasone propionate is a corticosteroid, which acts as an anti-inflammatory agent. When inhaled, it directly targets the airways in the lungs, reducing inflammation and swelling. This helps to decrease the production of mucus and makes breathing easier. By reducing inflammation, fluticasone propionate helps prevent asthma attacks and reduces the frequency and severity of COPD exacerbations. It works by suppressing the release of inflammatory substances, such as cytokines and chemokines, from cells in the airway lining. Regular use of fluticasone propionate helps to build up a protective effect in the airways, making them less sensitive to triggers that can cause asthma or COPD symptoms.
• Salmeterol is a long-acting beta2-adrenergic agonist (LABA). It works by relaxing the smooth muscles surrounding the airways, causing them to widen. This bronchodilation effect helps to improve airflow and makes it easier to breathe. Unlike short-acting bronchodilators, salmeterol provides relief for up to 12 hours, making it effective for preventing symptoms, especially at night. Salmeterol works by stimulating beta2-adrenergic receptors on the surface of airway smooth muscle cells. This stimulation leads to an increase in cyclic AMP (cAMP) levels within the cells, which in turn causes the muscles to relax. The bronchodilating effect of salmeterol helps to alleviate symptoms such as wheezing, shortness of breath, and chest tightness.
• The combination of fluticasone propionate and salmeterol in SERETIDE ACCUHALER provides both anti-inflammatory and bronchodilator effects. The fluticasone reduces inflammation and prevents airway narrowing, while the salmeterol opens up the airways for easier breathing. Regular use of SERETIDE ACCUHALER helps to control symptoms, reduce the frequency of asthma attacks or COPD exacerbations, and improve overall lung function. It is important to use SERETIDE ACCUHALER as prescribed by your doctor, even if you are feeling well, to maintain optimal control of your respiratory condition. This dual-action approach addresses both the underlying inflammation and the bronchoconstriction associated with these respiratory conditions, offering comprehensive symptom control and improved quality of life for patients.
• In summary, Fluticasone propionate reduces inflammation in the airways, while salmeterol relaxes airway muscles to improve airflow. Using SERETIDE ACCUHALER regularly helps manage symptoms and prevent attacks by addressing both inflammation and airway constriction.

Like all medicines, SERETIDE ACCUHALER 50/100 28MD can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Thrush (sore, creamy, raised patches) in the mouth and throat. * Pneumonia (lung infection) in COPD patients. * Hoarseness/loss of voice. * Headache. * Shaking, unsteady heartbeat. **Uncommon Side Effects (may affect up to 1 in 100 people):** * Muscle cramps. * Anxiety, sleep disturbances, behavioral changes including hyperactivity and irritability (particularly in children). * Bruising. * Dry mouth. * Skin rash. * Cataract * A very fast heartbeat (tachycardia). * Worsening of asthma symptoms. **Rare Side Effects (may affect up to 1 in 1,000 people):** * Difficulty breathing. * Glaucoma * Allergic reactions such as skin rash, swelling, and itching. * Decreased bone mineral density (osteoporosis). * Cushing's syndrome (moon face, weight gain, high blood pressure). **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Increased blood sugar levels (hyperglycemia). * Uneven heart beat (arrhythmias). * Candida infection **Other Possible Side Effects:** * Depression or aggression. **Important:** Tell your doctor if you experience any side effects, especially if they are severe or persistent. This is not an exhaustive list, and other side effects may occur. Seek medical advice for any concerns about your health or medication.

• If you miss a dose of SERETIDE ACCUHALER, take it as soon as you remember.
• However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for a missed one.

• Keep SERETIDE ACCUHALER 50/100 28MD away from the reach of children and pets.
• Store SERETIDE ACCUHALER 50/100 28MD at room temperature.

• **Understand Your Inhaler:** SERETIDE ACCUHALER 50/100 is a combination inhaler containing fluticasone (a corticosteroid) and salmeterol (a long-acting beta-agonist). Fluticasone reduces inflammation in the lungs, while salmeterol helps to open the airways. It's crucial to understand how to use the Accuhaler device correctly. Ask your doctor or pharmacist for a demonstration if you're unsure.
• **Consistent Daily Use is Key:** For optimal results, use SERETIDE ACCUHALER 50/100 every day, even when you feel well. This medication is designed to control your asthma or COPD symptoms long-term. Missing doses can increase the risk of symptoms returning.
• **Proper Inhalation Technique Matters:** Ensure a tight seal around the mouthpiece with your lips. Inhale deeply and steadily through the Accuhaler, not through your nose. Hold your breath for about 10 seconds after inhalation to allow the medication to reach deep into your lungs. Rinse your mouth with water after each use to prevent oral thrush.
• **Monitor for Side Effects:** Be aware of potential side effects, such as oral thrush (white patches in the mouth), hoarseness, sore throat, or headache. If you experience any persistent or bothersome side effects, consult your doctor. Rarely, SERETIDE can cause more serious side effects like pneumonia, especially in COPD patients. Report any new or worsening respiratory symptoms promptly.
• **Keep Track of Doses and Refills:** The SERETIDE ACCUHALER 50/100 contains 28 doses. Keep track of how many doses you have used and refill your prescription before you run out. Always have a rescue inhaler (such as albuterol) available for sudden asthma symptoms. Do not use SERETIDE to relieve sudden breathlessness. Store the Accuhaler in a cool, dry place, away from direct sunlight and moisture.

• SERETIDE ACCUHALER 50/100 28MD is administered through inhalation and is rapidly absorbed into the bloodstream. Therefore, food is unlikely to affect how this medicine works. You can use SERETIDE ACCUHALER 50/100 28MD without regard to food.