SERETIDE ACCUHALER 50/500

How SERETIDE ACCUHALER 50/500 Works

• SERETIDE ACCUHALER 50/500 is a combination inhaler containing two active ingredients: fluticasone propionate and salmeterol. These components work synergistically to manage asthma and chronic obstructive pulmonary disease (COPD).
• Fluticasone propionate is a corticosteroid, a type of anti-inflammatory medicine. When inhaled, it reduces inflammation in the airways. This action decreases swelling and mucus production, making it easier to breathe. Regular use of fluticasone propionate helps to prevent asthma symptoms and COPD exacerbations. It is important to note that corticosteroids do not provide immediate relief of breathing difficulties.
• Salmeterol is a long-acting beta2-adrenergic agonist (LABA). It works by relaxing the muscles surrounding the airways in the lungs, which allows the airways to widen. This bronchodilation effect helps to improve airflow and relieve symptoms such as wheezing, shortness of breath, and chest tightness. The effects of salmeterol last for about 12 hours, making it a long-acting bronchodilator. It provides bronchodilation for a longer time compared to short-acting beta2-agonists like albuterol.
• The combination of fluticasone propionate and salmeterol in SERETIDE ACCUHALER 50/500 provides both anti-inflammatory and bronchodilator effects. Fluticasone reduces inflammation and prevents symptoms, while salmeterol provides long-lasting relief from bronchoconstriction. This dual action helps to control asthma and COPD symptoms more effectively than using either medication alone.
• It is crucial to use SERETIDE ACCUHALER 50/500 regularly as prescribed by your doctor, even if you feel well. This helps to maintain control of your respiratory condition. The Accuhaler device delivers a consistent dose of medication with each inhalation, ensuring effective treatment. Proper technique is necessary for best results.
• SERETIDE ACCUHALER 50/500 does not replace rescue inhalers (e.g., albuterol) for sudden asthma symptoms. It is designed for long-term control. If you experience a sudden onset of breathlessness or wheezing, use your rescue inhaler immediately. Contact your healthcare provider if your symptoms worsen or if you need to use your rescue inhaler more frequently than usual.

Like all medicines, Seretide Accuhaler can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Oral thrush (sore, creamy, raised patches in the mouth). * Pneumonia (lung infection) in COPD patients. * Hoarseness/voice alteration. * Bruising. * Aches in muscles, painful joints. * Headache. **Uncommon side effects (may affect up to 1 in 100 people):** * Increase in blood sugar (hyperglycaemia). * Cataract (clouding of the lens in the eye). * Feeling worried. * Sleeping problems. * Shaking. * Fast heartbeat. * Coughing fits. * Irritation of the throat. * Disturbed sleep. * Skin rash. **Rare side effects (may affect up to 1 in 1,000 people):** * Breathing difficulties or wheezing gets worse just after taking Seretide Accuhaler. * Seretide Accuhaler may affect the normal production of steroid hormones in the body, particularly if you have taken high doses for long periods. * Glaucoma (increased pressure in the eye). * Changes in behaviour, such as being unusually active and irritable (these effects are mainly seen in children). * Uneven heart beat or heart misses a beat (arrhythmias). * Fungal infection in the oesophagus (gullet). **Very rare side effects (may affect up to 1 in 10,000 people):** * Swelling of the face or mouth (angioedema). * Breathing difficulties (bronchospasm). **Other possible side effects:** * Depression or aggression. * Changes in your bones, making them thinner. * Weight gain.

• If you miss a dose of SERETIDE ACCUHALER 50/500, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Keep SERETIDE ACCUHALER 50/500 away from the reach of children and pets.
• Store SERETIDE ACCUHALER 50/500 at room temperature.

• SERETIDE ACCUHALER 50/500 is administered via inhalation, and its absorption into the bloodstream is minimal. Therefore, it is unlikely to interact with food. You can use SERETIDE ACCUHALER 50/500 without regard to food intake.