SETOLAC MR TABLET 10'S

How SETOLAC MR TABLET 10'S Works

• SETOLAC MR TABLET 10'S is a combination medicine designed to alleviate pain and inflammation, particularly in musculoskeletal conditions. It contains three active ingredients: Aceclofenac, Paracetamol, and Tizanidine.
• Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are chemicals responsible for pain, inflammation, and fever. By reducing prostaglandin synthesis, Aceclofenac helps to reduce pain, swelling, and inflammation in the affected area. It primarily targets the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are involved in prostaglandin production.
• Paracetamol, also known as Acetaminophen, is an analgesic and antipyretic. It primarily works by inhibiting prostaglandin synthesis in the brain, which helps to reduce pain and fever. However, its anti-inflammatory effects are minimal compared to NSAIDs like Aceclofenac. Paracetamol is believed to act on the central nervous system to raise the pain threshold, providing relief from mild to moderate pain.
• Tizanidine is a muscle relaxant that works by acting on the central nervous system. It is an alpha-2 adrenergic agonist, which means it binds to alpha-2 adrenergic receptors in the brain and spinal cord. This action reduces the release of excitatory neurotransmitters, which in turn decreases muscle spasticity and relieves muscle spasms. By reducing muscle tone and spasms, Tizanidine helps to alleviate pain and improve mobility in conditions associated with muscle stiffness and tightness.
• In combination, these three ingredients provide a synergistic effect. Aceclofenac addresses inflammation and pain at the source, Paracetamol enhances pain relief, and Tizanidine relaxes muscles to further reduce discomfort and improve movement. This multi-pronged approach makes SETOLAC MR TABLET 10'S effective in managing pain associated with muscle spasms, joint pain, and other musculoskeletal conditions. The modified-release (MR) formulation ensures a sustained release of the active ingredients, providing prolonged pain relief and reducing the frequency of dosing.
• The overall effect of SETOLAC MR TABLET 10'S is to reduce pain, inflammation, and muscle spasms, thereby improving comfort and mobility for individuals suffering from musculoskeletal disorders. It is important to use this medication as prescribed by a healthcare professional to ensure its safe and effective use.

Common side effects of Setolac MR Tablet may include nausea, vomiting, stomach pain, heartburn, diarrhea, constipation, loss of appetite, drowsiness, dizziness, headache, dry mouth, blurred vision, and skin rash or itching. Less common but potentially serious side effects include stomach ulcers, bleeding, allergic reactions (such as swelling of the face, lips, or tongue, difficulty breathing), liver problems (such as jaundice, dark urine, persistent fatigue), kidney problems (such as changes in urine output, swelling of the ankles or feet), and cardiovascular issues (such as chest pain, palpitations). Muscle weakness, increased sweating, anxiety, confusion, and sleep disturbances have also been reported in some cases. This is not an exhaustive list; if you experience any unusual symptoms, discontinue use and consult your doctor.

• If you miss a dose of SETOLAC MR TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep SETOLAC MR TAB 1X10 away from the reach of children and pets.
• Store SETOLAC MR TAB 1X10 at room temperature.

• While taking SETOLAC MR TABLET 10'S, be cautious about consuming grapefruit juice, as it may increase the drug's concentration in your blood, potentially leading to increased side effects. It is generally recommended to avoid or limit grapefruit juice consumption during treatment with this medication.
• SETOLAC MR TABLET 10'S can be taken with or without food, as food does not significantly affect its absorption or efficacy. However, if you experience stomach upset, taking it with food may help alleviate discomfort.