SIGRIMA 420MG/14ML INJECTION
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SIGRIMA 420MG/14ML INJECTION
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SIGRIMA 420MG/14ML INJECTION

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By ZYDUS LIFESCIENCES LIMITED

MRP

79995

₹68000

14.99 % OFF

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Product Details
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About SIGRIMA 420MG/14ML INJECTION

  • SIGRIMA 420MG/14ML INJECTION is a targeted therapy medication designed to treat a specific type of breast cancer known as HER2-positive breast cancer. This cancer has too much of a protein called HER2 on the surface of its cells, which helps them grow and divide. SIGRIMA contains two active ingredients, pertuzumab and trastuzumab, which work together by targeting and blocking the signals from this HER2 protein, slowing down or stopping the growth of cancer cells.
  • This injection is used in different situations for HER2-positive breast cancer. It is given when the cancer has spread to other parts of the body (metastatic breast cancer) or when the cancer has returned after previous treatment. SIGRIMA 420MG/14ML INJECTION may also be used before or after surgery for patients with early-stage HER2-positive breast cancer that has not yet spread. Using this therapy alongside standard chemotherapy in early-stage cancer can significantly reduce the chance of the cancer coming back and improve the time patients live without the disease worsening.
  • Before receiving SIGRIMA 420MG/14ML INJECTION, it is very important to discuss your complete medical history with your doctor. Be sure to mention any existing heart problems, as this medication can sometimes affect the heart. Inform them if you have had radiotherapy in the past or if you have any known allergies. This medication is administered by a healthcare professional and is not suitable for use in children or adolescents under the age of 18. Your doctor will monitor your health closely during treatment and discuss any potential side effects you might experience. Remember, SIGRIMA is part of a larger treatment plan tailored specifically for you.

Side Effects of SIGRIMA 420MG/14ML INJECTION
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Like all medications, SIGRIMA 420MG/14ML INJECTION can cause some side effects, although not everyone will experience them.

Safety Advice for SIGRIMA 420MG/14ML INJECTION
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Breastfeeding Safety Icon

BreastFeeding

Consult a Doctor

It is unknown whether SIGRIMA 420MG/14ML INJECTION is excreted in human milk. So breastfeeding women should consult their doctor before taking it.

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Driving

Consult a Doctor

Patients should always monitor their response to the SIGRIMA 420MG/14ML INJECTION medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.

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Liver Function

Consult a Doctor

Patients with pre-existing liver disease or impaired liver function may be at increased risk for the potential side effects of SIGRIMA 420MG/14ML INJECTION, including liver toxicity. So patients should discuss it with their healthcare provider before taking it.

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Lungs

Consult a Doctor

SIGRIMA 420MG/14ML INJECTION can cause side effects, and the safety of their use in the lungs depends on several factors. Patients should consult their doctor if they have any pre-existing health condition before taking this medication

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Pregnancy

Consult a Doctor

SIGRIMA 420MG/14ML INJECTION may harm the developing fetus, so it is unsafe to use it during pregnancy

Dosage of SIGRIMA 420MG/14ML INJECTION
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  • SIGRIMA 420MG/14ML INJECTION is a powerful medicine that is given directly into a vein (intravenously) by a doctor or nurse. This type of administration ensures the medication works effectively. It's absolutely crucial to always follow the specific instructions provided by your healthcare provider about how much SIGRIMA 420MG/14ML INJECTION you should receive and exactly when and how it will be given. They determine the correct dose based on your condition and medical history. You should never try to change the dose or skip a scheduled administration. If you happen to miss an appointment for your infusion, contact your healthcare provider immediately to reschedule. Do not attempt to catch up by taking a double dose, as this can be dangerous and lead to unwanted side effects. Your healthcare team will monitor you during and after the administration. Feel free to ask them any questions you have about the treatment.

How to store SIGRIMA 420MG/14ML INJECTION?
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  • Keep SIGRIMA 420MG INJ 14ML away from the reach of children and pets.
  • Store SIGRIMA 420MG INJ 14ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of SIGRIMA 420MG/14ML INJECTION
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  • Human epidermal growth factor receptor 2 (HER2) is a protein often found in increased amounts on the surface of certain cancer cells, particularly in some types of breast cancer. This excess HER2 acts like a signal receiver, constantly telling the cancer cells to grow and divide rapidly. SIGRIMA 420MG/14ML INJECTION is a targeted therapy specifically designed to combat these HER2-positive cancers. It works by recognizing and binding directly to the HER2 receptors on the surface of these malignant cells. Once bound, it effectively blocks the receptors, preventing them from receiving the growth signals that drive uncontrolled cell proliferation. By interrupting this critical communication pathway, SIGRIMA 420MG/14ML INJECTION helps to slow or stop the growth of the cancer cells, offering a crucial treatment option for patients with HER2-positive disease. This targeted approach minimizes damage to healthy cells compared to traditional chemotherapy, focusing its action where it is needed most.

How to use SIGRIMA 420MG/14ML INJECTION
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  • SIGRIMA 420MG/14ML INJECTION is a special kind of medicine that is given directly into your vein. This is called intravenous or IV administration. Because it goes directly into your bloodstream, it must always be given by a trained healthcare professional, like a doctor or nurse, in a clinic or hospital setting. It is very important to strictly follow all instructions given by your healthcare provider about this medicine. This includes the exact amount (dosage) you receive, how it is given, and how often you need to receive it. Do not try to give yourself this injection. If you miss a scheduled dose, contact your healthcare provider right away to ask what you should do. Never take a double dose to try and catch up for a missed one, as this can be harmful. This injection is part of your overall treatment plan, and following the healthcare provider's guidance is key to getting the best results.

FAQs

Can SIGRIMA 420MG/14ML INJECTION cause infertility?

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SIGRIMA 420MG/14ML INJECTION can affect fertility in some patients, although the extent of this effect is not well-understood. Women who wish to preserve their fertility should discuss their options with their healthcare provider before starting treatment with these drugs.

Can SIGRIMA 420MG/14ML INJECTION be used together with chemotherapy?

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Yes, SIGRIMA 420MG/14ML INJECTION is often combined with chemotherapy to treat HER2-positive breast cancer. This combination therapy effectively reduces the risk of recurrence and improves overall survival in patients with HER2-positive breast cancer.

Can I take SIGRIMA 420MG/14ML INJECTION if I have TB?

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If you have active tuberculosis (TB) infection, SIGRIMA 420MG/14ML INJECTION should not be used until the TB infection has been treated and is under control. This drug can suppress the immune system, worsening TB or other infections.

Does SIGRIMA 420MG/14ML INJECTION interact with other drugs?

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Yes, SIGRIMA 420MG/14ML INJECTION can interact with other medications. It is important to inform your doctor about all the medications, supplements, or herbal products you are taking to avoid potential interactions.

What are the important warnings and precautions for SIGRIMA 420MG/14ML INJECTION?

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If you are prescribed SIGRIMA 420MG/14ML INJECTION, or any other medication, it is important to carefully read and understand the warnings and precautions associated with the medication. Patients should be monitored for signs of an allergic reaction, such as rash, itching, or swelling, and should seek immediate medical attention if these symptoms occur. It should be used with caution in patients with severe renal impairment. Talk to the physician if you have heart problems, have had radiotherapy, or have allergic conditions. Use effective birth control during the treatment and at least seven months after the last dose. Always maintain a healthy and balanced diet to support your overall health and well-being.

What is the main molecule in SIGRIMA 420MG/14ML INJECTION?

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The main molecule in SIGRIMA 420MG/14ML INJECTION is PERTUZUMAB.

What type of cancer is SIGRIMA 420MG/14ML INJECTION used for?

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SIGRIMA 420MG/14ML INJECTION is used in the treatment of certain types of cancer, particularly HER2-positive breast cancer, often in combination with other therapies.

How does SIGRIMA 420MG/14ML INJECTION work to treat cancer?

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SIGRIMA 420MG/14ML INJECTION is a targeted therapy that works by blocking the HER2 protein, which is often overexpressed in certain cancers and helps cancer cells grow and divide. By blocking HER2, it helps slow down or stop cancer growth.

References

Book Icon

Roche products limited, Electronic medicines compendium (EMC)

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zhu Chenjing et al.; Safety and efficacy evaluation of pertuzumab in patients with solid tumors; Medicine;

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Sandra M Swain et al; Sigrima 420mg Injection, and docetaxel in HER2-positive metastatic breast cancer; The New England Journal of Medicine;

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Ratings & Review

Good service. Public relations are very good.

Pallav Bhatt

Reviewed on 22-11-2022

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Excellent service and support 24/7 Supportive and co operative staff.

Ajay Nayak Dhadkan

Reviewed on 13-01-2024

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Best medicines at best prices, thanks medkart

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Reviewed on 05-08-2023

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(5/5)

Great experience at medkart pharmacy, medicines are available at very affordable rate

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Reviewed on 17-01-2024

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(5/5)

Nice discount and best quality medicine generic ..thank you

Mihir Ujjaniya

Reviewed on 29-12-2023

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(4/5)


Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

Country of Origin -

India

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Disclaimer

Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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