SILODAL M 50 TABLET 10'S

How SILODAL M 50 TABLET 10'S Works

• SILODAL M 50 TABLET 10'S is a combination medication designed to manage the symptoms of benign prostatic hyperplasia (BPH), commonly known as an enlarged prostate, particularly when accompanied by erectile dysfunction. It combines two active ingredients: silodosin and tadalafil, each addressing different aspects of these conditions.
• Silodosin belongs to a class of drugs called alpha-adrenergic blockers. It works by selectively blocking alpha-1A adrenergic receptors, which are primarily located in the prostate gland, bladder neck, and urethra. By blocking these receptors, silodosin relaxes the smooth muscles in these areas. This relaxation reduces the obstruction of urine flow, making it easier to urinate and alleviating symptoms such as frequent urination, urgency, weak stream, and nighttime urination (nocturia) associated with BPH. Silodosin's selective action minimizes the impact on blood pressure, reducing the risk of dizziness or lightheadedness compared to non-selective alpha-blockers.
• Tadalafil is a phosphodiesterase-5 (PDE5) inhibitor. It primarily enhances erectile function by increasing blood flow to the penis during sexual stimulation. PDE5 inhibitors prevent the breakdown of cyclic guanosine monophosphate (cGMP), a substance that relaxes smooth muscles and increases blood flow. By inhibiting PDE5, tadalafil allows cGMP to accumulate, leading to vasodilation in the penis and facilitating an erection. In the context of BPH, tadalafil also helps to relax the smooth muscles in the prostate and bladder neck, contributing to improved urinary symptoms. The combined effect of smooth muscle relaxation in both the prostate and penis makes tadalafil a useful component in managing both BPH and erectile dysfunction.
• The synergistic action of silodosin and tadalafil in SILODAL M 50 TABLET 10'S provides a comprehensive approach to managing BPH symptoms and erectile dysfunction. Silodosin primarily addresses the urinary symptoms by relaxing the prostate and bladder neck, while tadalafil improves erectile function and further aids in relaxing the smooth muscles, contributing to better urinary flow. This dual mechanism makes SILODAL M 50 TABLET 10'S an effective option for men experiencing both conditions simultaneously. It is crucial to use this medication under the guidance of a healthcare professional, who can assess individual patient needs and monitor for any potential side effects.

Common side effects of SILODAL M 50 Tablet may include: Dizziness, Lightheadedness, Fainting, Headache, Nasal congestion (stuffy nose), Orthostatic hypotension (low blood pressure upon standing), Palpitations, Rapid heart rate, Diarrhea, Constipation, Nausea, Vomiting, Dry mouth, Fatigue, Peripheral edema (swelling in the extremities), Sexual dysfunction (such as decreased libido, erectile dysfunction, ejaculatory disorders including retrograde ejaculation), Insomnia, Anxiety, Asthenia (weakness), Visual disturbances (blurred vision). Less common or rare side effects may include: Allergic reactions (rash, itching, hives, swelling), Priapism (prolonged and painful erection), Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery, Angina (chest pain), Arrhythmias (irregular heartbeats), Severe hypotension, Stroke, Stevens-Johnson syndrome (a severe skin reaction), Liver dysfunction (elevated liver enzymes), Urinary incontinence, Gynecomastia (enlargement of male breasts).

• If you miss a dose of SILODAL M 50 TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep SILODAL M 50MG TAB 1X10 away from the reach of children and pets.
• Store SILODAL M 50MG TAB 1X10 at room temperature.

• **Take Silodal M 50 Tablet as Prescribed:** Always adhere to your doctor's instructions regarding dosage and timing. Consistency is key to effectively managing your condition. This medication is typically prescribed for the treatment of benign prostatic hyperplasia (BPH).
• **Be Mindful of Dizziness:** Silodal M 50 can cause dizziness, especially when you first start taking it or when the dosage is increased. Rise slowly from sitting or lying down to minimize this effect. Avoid driving or operating heavy machinery until you know how the medication affects you. If dizziness persists or worsens, consult your doctor.
• **Monitor Blood Pressure Regularly:** This medication can affect your blood pressure. Monitor your blood pressure regularly, especially during the initial phase of treatment. Report any significant changes or concerns to your healthcare provider promptly.
• **Inform Your Doctor About Other Medications:** Before starting Silodal M 50, inform your doctor about all other medications, supplements, and herbal products you are taking. This is crucial to avoid potential drug interactions that could impact the effectiveness of the treatment or cause adverse effects. Specific attention should be given to medications for erectile dysfunction or blood pressure.
• **Report Any Persistent Side Effects:** While Silodal M 50 is generally well-tolerated, be vigilant for any persistent or bothersome side effects. These may include nasal congestion, ejaculation problems, or headache. Promptly report any such issues to your doctor for appropriate management. Do not discontinue the medication without consulting your healthcare provider, as this could lead to a worsening of your condition.
• **Lifestyle adjustments:** In addition to medication, consider lifestyle adjustments such as reducing caffeine and alcohol intake, and practicing pelvic floor exercises to support bladder control.

• SILODAL M 50 TABLET 10'S can be taken with or without food, but it is advisable to take it at a fixed time to maintain consistent blood levels of the medicine. Avoid taking it with high-fat meals, as this may reduce the absorption of the medicine.