SITADAPA 5/50MG TABLET 10'S
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SITADAPA 5/50MG TABLET 10'S
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SITADAPA 5/50MG TABLET 10'S

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SITADAPA 5/50MG TABLET 10'S

By MACLEODS PHARMACEUTICALS PRIVATE LIMITED

MRP

142

₹120.7

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About SITADAPA 5/50MG TABLET 10'S

  • SITADAPA 5/50MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It combines two powerful active ingredients, sitagliptin and dapagliflozin, to effectively manage blood sugar levels. This medication is typically prescribed when diet and exercise alone are not sufficient to achieve adequate glycemic control.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It works by increasing the amount of incretin hormones in the body. These hormones help to stimulate insulin release from the pancreas and decrease the amount of glucose produced by the liver. By enhancing the action of incretin hormones, sitagliptin helps to lower blood sugar levels, particularly after meals.
  • Dapagliflozin, on the other hand, is an SGLT2 inhibitor (sodium-glucose co-transporter 2 inhibitor). It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated from the body through urine. This mechanism helps to lower blood sugar levels and may also lead to modest weight loss and blood pressure reduction.
  • SITADAPA 5/50MG TABLET is usually taken once daily, with or without food. It is important to follow your doctor's instructions carefully regarding dosage and timing. Common side effects may include urinary tract infections, yeast infections, and increased urination. It is essential to stay hydrated while taking this medication. This medicine is not recommended for patients with type 1 diabetes or diabetic ketoacidosis.
  • Before starting SITADAPA 5/50MG TABLET, inform your doctor about any pre-existing medical conditions, such as kidney problems, liver problems, or heart problems. Also, disclose all other medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Regular monitoring of blood sugar levels and kidney function is recommended while taking this medication. Always consult your healthcare provider for personalized medical advice and treatment.

Uses of SITADAPA 5/50MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Used in combination with diet and exercise
  • Improving blood sugar control in adults
  • May be used with other diabetes medications

How SITADAPA 5/50MG TABLET 10'S Works

  • SITADAPA 5/50MG TABLET is a combination medicine containing Sitagliptin and Dapagliflozin. It's prescribed to manage blood sugar levels in adults with type 2 diabetes, especially when diet and exercise aren't enough. This dual-action medication tackles high blood sugar through different mechanisms, offering a comprehensive approach to glycemic control.
  • Sitagliptin, a DPP-4 inhibitor, enhances the body's natural ability to lower blood sugar. Here's how it works: After you eat, your gut releases incretin hormones. These hormones signal the pancreas to release insulin and tell the liver to stop producing glucose. DPP-4 is an enzyme that breaks down incretins. Sitagliptin inhibits DPP-4, thereby increasing incretin levels in the body. This results in more insulin release after meals and less glucose production by the liver, ultimately lowering blood sugar levels.
  • Dapagliflozin, an SGLT2 inhibitor, works in the kidneys to remove excess glucose from the body through urine. Here's the process: The kidneys filter glucose from the blood. SGLT2 (sodium-glucose co-transporter 2) is a protein in the kidneys that reabsorbs glucose back into the bloodstream. Dapagliflozin blocks SGLT2, preventing the reabsorption of glucose. This causes the extra glucose to be excreted in the urine, which lowers blood sugar levels. In addition to lowering blood sugar, Dapagliflozin can also lead to modest weight loss and blood pressure reduction in some patients.
  • By combining these two medications, SITADAPA 5/50MG TABLET provides a synergistic effect in controlling blood sugar. Sitagliptin boosts insulin release and reduces glucose production, while Dapagliflozin removes excess glucose from the body. This dual action helps to achieve and maintain target blood sugar levels more effectively than either medication alone.
  • It's crucial to remember that SITADAPA 5/50MG TABLET should be used in conjunction with a healthy diet and regular exercise. Your doctor will monitor your blood sugar levels and adjust your dosage as needed. It is important to follow your doctor's instructions carefully and to report any side effects you may experience.

Side Effects of SITADAPA 5/50MG TABLET 10'SArrow

Possible side effects of SITADAPA 5/50MG TABLET may include: * **Common:** Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, dizziness, fatigue, hypoglycemia (low blood sugar), upper respiratory tract infection, stuffy or runny nose, sore throat. * **Uncommon:** Constipation, flatulence, pancreatitis (inflammation of the pancreas), skin rash, itching, angioedema (swelling of the face, lips, tongue, or throat), joint pain, muscle pain, back pain, Stevens-Johnson syndrome (a severe skin reaction), bullous pemphigoid (a skin disorder causing blisters). * **Rare:** Severe allergic reactions (anaphylaxis), kidney problems. **Note:** This is not an exhaustive list. If you experience any unusual symptoms while taking SITADAPA 5/50MG TABLET, consult your doctor immediately.

Safety Advice for SITADAPA 5/50MG TABLET 10'SArrow

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Dosage of SITADAPA 5/50MG TABLET 10'SArrow

  • The recommended dosage of 'SITADAPA 5/50MG TABLET 10'S' is typically one tablet taken orally once daily. It is crucial to adhere to your physician's instructions regarding dosage and timing. The tablet should be swallowed whole with a glass of water and can be taken with or without food. However, consistency in taking the medication, such as always taking it with food, or always taking it on an empty stomach, can help maintain steady blood sugar levels.
  • Your doctor will determine the appropriate dosage based on your individual needs, considering factors such as your blood sugar levels, kidney function, and other medications you may be taking. It's essential to inform your doctor about all existing medications, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.
  • Do not crush, chew, or break the tablet unless specifically instructed by your doctor. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to compensate for a missed one.
  • It's important to monitor your blood sugar levels regularly as directed by your healthcare provider while taking 'SITADAPA 5/50MG TABLET 10'S'. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Regular follow-up appointments with your doctor are crucial for monitoring your condition and ensuring the medication's effectiveness.
  • Take 'SITADAPA 5/50MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of SITADAPA 5/50MG TABLET 10'S?Arrow

  • If you miss a dose of SITADAPA 5/50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store SITADAPA 5/50MG TABLET 10'S?Arrow

  • Keep SITADAPA 5/50MG TAB 1X10 away from the reach of children and pets.
  • Store SITADAPA 5/50MG TAB 1X10 at room temperature.

Benefits of SITADAPA 5/50MG TABLET 10'SArrow

  • SITADAPA 5/50MG TABLET 10'S is a combination medicine specifically designed to help manage blood sugar levels in adults diagnosed with type 2 diabetes mellitus. It combines two powerful active ingredients, sitagliptin and dapagliflozin, each working through different mechanisms to achieve optimal glycemic control.
  • Sitagliptin belongs to a class of drugs known as DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). It functions by increasing the levels of incretin hormones in the body. These hormones play a crucial role in regulating blood sugar by stimulating the release of insulin after meals and reducing the secretion of glucagon, a hormone that raises blood sugar levels. By enhancing the activity of incretin hormones, sitagliptin helps to lower post-meal blood sugar spikes and improve overall glucose control.
  • Dapagliflozin, on the other hand, is classified as an SGLT2 inhibitor (sodium-glucose cotransporter-2 inhibitor). It works by preventing the kidneys from reabsorbing glucose back into the bloodstream. Instead, the excess glucose is eliminated from the body through urine. This mechanism not only lowers blood sugar levels but also offers the added benefit of reducing body weight and blood pressure in some individuals.
  • The combined action of sitagliptin and dapagliflozin provides a comprehensive approach to managing type 2 diabetes. By targeting different pathways involved in glucose regulation, SITADAPA 5/50MG TABLET 10'S effectively lowers both fasting and post-meal blood sugar levels. This can lead to significant improvements in HbA1c (glycated hemoglobin), a measure of long-term blood sugar control.
  • Beyond glycemic control, SITADAPA 5/50MG TABLET 10'S may offer additional benefits. Dapagliflozin has been shown to have a protective effect on the kidneys and heart in certain patients with type 2 diabetes. It can help reduce the risk of cardiovascular events such as heart attack and stroke, as well as slow the progression of kidney disease. These benefits are particularly important for individuals with diabetes, who are at a higher risk of developing these complications.
  • SITADAPA 5/50MG TABLET 10'S is typically taken once daily, with or without food, as prescribed by your doctor. It is important to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly. Like all medications, SITADAPA 5/50MG TABLET 10'S may cause side effects, such as urinary tract infections, yeast infections, and changes in urination. It is important to discuss any concerns or side effects with your doctor.
  • In summary, SITADAPA 5/50MG TABLET 10'S offers a dual-action approach to managing type 2 diabetes by combining the benefits of a DPP-4 inhibitor and an SGLT2 inhibitor. It effectively lowers blood sugar levels, may reduce body weight and blood pressure, and may offer protection against cardiovascular and kidney complications. When used as part of a comprehensive diabetes management plan, including diet, exercise, and regular monitoring, SITADAPA 5/50MG TABLET 10'S can help individuals with type 2 diabetes achieve better health outcomes and improve their overall quality of life.

How to use SITADAPA 5/50MG TABLET 10'SArrow

  • SITADAPA 5/50MG TABLET 10'S is an oral medication and should be taken exactly as prescribed by your doctor. It's typically taken once or twice daily, with or without food, but consistency is key for optimal blood sugar control. Try to take it at the same time(s) each day to help you remember.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released in your body. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist; they may be able to offer alternative formulations or helpful techniques.
  • Your doctor will determine the appropriate dosage based on your individual needs and response to treatment. It's crucial to adhere to the prescribed dosage and not to self-adjust it. Doing so can lead to either inadequate blood sugar control or an increased risk of side effects.
  • If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.
  • SITADAPA 5/50MG TABLET 10'S is most effective when combined with a healthy diet and regular exercise. Follow your doctor's or dietitian's recommendations for a balanced meal plan and incorporate physical activity into your daily routine.
  • It is important to regularly monitor your blood sugar levels as directed by your healthcare provider. Keep track of your readings and share them with your doctor during follow-up appointments. This will help them assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with SITADAPA 5/50MG TABLET 10'S. Certain medications can affect blood sugar levels or increase the risk of side effects.
  • Continue taking SITADAPA 5/50MG TABLET 10'S even if you feel well, unless your doctor advises you to stop. This medication helps manage your blood sugar levels, and it's essential to maintain consistent control, even when you don't have noticeable symptoms.
  • Store SITADAPA 5/50MG TABLET 10'S at room temperature, away from moisture and heat. Keep it out of the reach of children.
  • Attend all scheduled follow-up appointments with your doctor to monitor your progress and address any concerns. Your doctor may order blood tests and other evaluations to assess your overall health and the effectiveness of your treatment.

Quick Tips for SITADAPA 5/50MG TABLET 10'SArrow

  • Take SITADAPA 5/50MG Tablet exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistency is key for managing blood sugar levels effectively.
  • SITADAPA 5/50MG Tablet should be taken with food to help prevent stomach upset and improve absorption of the medication. Follow your doctor's instructions regarding timing in relation to meals.
  • Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. Keeping a log of your blood sugar readings can help you and your doctor assess how well the medication is working and make necessary adjustments.
  • Maintain a healthy lifestyle while taking SITADAPA 5/50MG Tablet. This includes following a balanced diet, engaging in regular physical activity, and managing your weight. These habits can significantly improve blood sugar control and overall health.
  • Be aware of the signs and symptoms of low blood sugar (hypoglycemia), such as shakiness, sweating, dizziness, and confusion. Carry a source of quick-acting sugar, such as glucose tablets or juice, with you at all times in case your blood sugar drops too low. Contact your doctor if you experience frequent or severe episodes of hypoglycemia.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting SITADAPA 5/50MG Tablet. Drug interactions can affect how the medication works and increase the risk of side effects.
  • Stay hydrated by drinking plenty of water throughout the day. Proper hydration is important for overall health and can also help regulate blood sugar levels.
  • Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups are essential for monitoring your diabetes and making sure your treatment plan is effective.
  • Store SITADAPA 5/50MG Tablet in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets.
  • If you experience any persistent or bothersome side effects while taking SITADAPA 5/50MG Tablet, such as nausea, diarrhea, or headache, contact your doctor for advice. Do not stop taking the medication without consulting your healthcare provider.

Food Interactions with SITADAPA 5/50MG TABLET 10'SArrow

  • SITADAPA 5/50MG TABLET 10'S can be taken with or without food. Food does not significantly affect the absorption or effectiveness of this medication. Follow your doctor's instructions regarding diet and lifestyle while taking this medicine.

FAQs

What is Sitadapa 5/50mg Tablet 10'S?Arrow

Sitadapa 5/50mg Tablet 10'S is a medication used to control high blood sugar levels in people with type 2 diabetes. It contains two medicines: Sitagliptin and Dapagliflozin.

What is Sitadapa 5/50mg Tablet 10'S used for?Arrow

Sitadapa 5/50mg Tablet 10'S is used to treat type 2 diabetes mellitus. It helps lower blood sugar levels.

How does Sitadapa 5/50mg Tablet 10'S work?Arrow

Sitadapa 5/50mg Tablet 10'S works in two ways: Sitagliptin increases insulin secretion and decreases glucagon secretion, while Dapagliflozin reduces glucose reabsorption by the kidneys, leading to more glucose being excreted in the urine.

What are the common side effects of Sitadapa 5/50mg Tablet 10'S?Arrow

Common side effects of Sitadapa 5/50mg Tablet 10'S include nausea, vomiting, diarrhea, abdominal pain, and headache.

How to store Sitadapa 5/50mg Tablet 10'S?Arrow

Store Sitadapa 5/50mg Tablet 10'S at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can Sitadapa 5/50mg Tablet 10'S be taken with or without food?Arrow

Sitadapa 5/50mg Tablet 10'S can be taken with or without food, but it is best to take it at the same time each day.

What happens if I miss a dose of Sitadapa 5/50mg Tablet 10'S?Arrow

If you miss a dose of Sitadapa 5/50mg Tablet 10'S, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose.

Is it safe to drink alcohol with Sitadapa 5/50mg Tablet 10'S?Arrow

Drinking alcohol with Sitadapa 5/50mg Tablet 10'S may lower your blood sugar levels. Therefore, it is best to limit or avoid alcohol consumption.

Is Sitadapa 5/50mg Tablet 10'S safe for pregnant or breastfeeding women?Arrow

Sitadapa 5/50mg Tablet 10'S is not safe for pregnant or breastfeeding women. It should only be used if the benefit outweighs the risk.

Can Sitadapa 5/50mg Tablet 10'S interact with other medications?Arrow

Sitadapa 5/50mg Tablet 10'S can interact with certain other medications, such as insulin, sulfonylureas, and diuretics. Tell your doctor if you are taking any other medications.

What are the symptoms of an overdose of Sitadapa 5/50mg Tablet 10'S?Arrow

Symptoms of an overdose of Sitadapa 5/50mg Tablet 10'S may include low blood sugar, nausea, vomiting, and abdominal pain.

What precautions should be followed while using Sitadapa 5/50mg Tablet 10'S?Arrow

While using Sitadapa 5/50mg Tablet 10'S, monitor your blood sugar levels regularly, drink plenty of water, and follow a healthy diet.

Does Sitadapa 5/50mg Tablet 10'S cause weight gain?Arrow

Sitadapa 5/50mg Tablet 10'S does not typically cause weight gain. However, some individuals may experience an increase in appetite, which could lead to weight gain.

Can Sitadapa 5/50mg Tablet 10'S cause kidney problems?Arrow

In rare cases, Sitadapa 5/50mg Tablet 10'S may cause kidney problems. Inform your doctor if you have a history of kidney disease.

Should Sitadapa 5/50mg Tablet 10'S be stopped abruptly?Arrow

Sitadapa 5/50mg Tablet 10'S should not be stopped abruptly. Do not stop the medication without consulting your doctor.

References

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JANUVIA (sitagliptin): European Medicines Agency (EMA) assessment report. This provides detailed information on the pharmacology, clinical trials, and safety profile of sitagliptin.

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JANUVIA (sitagliptin) US FDA Prescribing Information. This document contains comprehensive information about sitagliptin, including its mechanism of action, pharmacokinetics, clinical studies, and safety information.

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Dapagliflozin: A review of its pharmacology, mechanism of action, and clinical use. Int J Clin Pract. 2014 May;68(5):689-702. doi: 10.1111/ijcp.12386. This article provides an overview of dapagliflozin's pharmacology, mechanism of action, and clinical efficacy.

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FARXIGA (dapagliflozin) US FDA Prescribing Information. This label provides information on dapagliflozin's indications, dosage, administration, contraindications, warnings, precautions, adverse reactions, and clinical studies.

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Sitagliptin DrugBank entry. A detailed resource providing chemical, pharmacological, and clinical information about sitagliptin.

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Dapagliflozin DrugBank entry. A detailed resource providing chemical, pharmacological, and clinical information about dapagliflozin.

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Sitagliptin. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: [Insert URL]. A review of sitagliptin's use, mechanism, and adverse effects.

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Dapagliflozin: Pharmacology, safety profile and potential clinical applications. Expert Opin Drug Metab Toxicol. 2019 Apr;15(4):313-322. doi: 10.1080/17425255.2019.1590775. Reviews dapagliflozin's pharmacology, safety and clinical applications.

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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