SITARA M 100/1000
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SITARA M 100/1000MG TABLET 10'S

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SITARA M 100/1000MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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179.75

₹152.79

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About SITARA M 100/1000MG TABLET 10'S

  • SITARA M 100/1000MG TABLET is a combination medication designed to manage type 2 diabetes effectively. It combines two powerful active ingredients: Sitagliptin and Metformin. Sitagliptin belongs to a class of drugs called DPP-4 inhibitors, which work by increasing the amount of insulin released by the pancreas and decreasing the amount of glucose produced by the liver. Metformin, on the other hand, is a biguanide that reduces glucose production in the liver and improves insulin sensitivity in the body's tissues. This dual action helps to lower blood sugar levels in individuals with type 2 diabetes.
  • This medication is typically prescribed when diet and exercise alone are not sufficient to control blood sugar levels. It is available in tablet form and is usually taken orally once or twice daily, depending on the doctor's instructions. The 100/1000MG dosage indicates that each tablet contains 100mg of Sitagliptin and 1000mg of Metformin. Consistent use of SITARA M 100/1000MG TABLET, along with a healthy lifestyle, can significantly improve glycemic control and reduce the risk of diabetes-related complications.
  • Before starting SITARA M 100/1000MG TABLET, it's crucial to inform your healthcare provider about any existing medical conditions, allergies, and other medications you are taking. Common side effects may include nausea, diarrhea, stomach upset, and headache. Regular monitoring of blood sugar levels and kidney function is recommended while taking this medication. It's essential to adhere to the prescribed dosage and follow your doctor's guidance for optimal results in managing your diabetes.

Uses of SITARA M 100/1000MG TABLET 10'S

  • Treatment of Type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Improving blood sugar control
  • Management of insulin resistance associated with Polycystic Ovary Syndrome (PCOS) (off-label use)

How SITARA M 100/1000MG TABLET 10'S Works

  • SITARA M 100/1000MG TABLET 10'S is a combination medication containing Sitagliptin and Metformin, designed to manage blood sugar levels in individuals with type 2 diabetes. It works through complementary mechanisms to achieve optimal glycemic control.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that inactivates incretin hormones. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released by the intestine in response to food intake. They stimulate insulin release from the pancreas and decrease glucagon secretion from the liver, both of which help lower blood glucose levels. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This leads to enhanced insulin secretion when blood sugar is high and reduced glucagon secretion when blood sugar is high, ultimately improving blood sugar control.
  • Metformin, on the other hand, is a biguanide that primarily works by reducing glucose production in the liver. It decreases hepatic glucose output by suppressing gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Metformin also improves insulin sensitivity in peripheral tissues, such as muscle and fat, allowing them to utilize glucose more effectively. This means that the body's cells are better able to take up glucose from the bloodstream, further contributing to lower blood sugar levels. Additionally, Metformin slows down the absorption of glucose from the intestines after a meal, preventing rapid spikes in blood sugar.
  • The synergistic action of Sitagliptin and Metformin addresses multiple aspects of glucose regulation. Sitagliptin enhances insulin secretion and reduces glucagon secretion in a glucose-dependent manner, while Metformin reduces hepatic glucose production, improves insulin sensitivity, and slows down glucose absorption. Together, they provide comprehensive control over blood sugar levels in individuals with type 2 diabetes, helping to maintain target HbA1c levels and reduce the risk of diabetes-related complications. It is important to note that SITARA M is most effective when used in conjunction with a healthy diet and regular exercise.
  • In summary, Sitagliptin optimizes the body's own ability to manage blood sugar by prolonging the activity of incretin hormones, while Metformin reduces the amount of glucose produced by the liver and enhances the body's response to insulin. This dual mechanism makes SITARA M an effective tool in managing type 2 diabetes.

Side Effects of SITARA M 100/1000MG TABLET 10'SArrow

The most common side effects of SITARA M 100/1000MG TABLET 10'S are nausea, vomiting, diarrhea, stomach pain, loss of appetite, metallic taste, and heartburn. Other possible side effects include: Headache, dizziness, fatigue, weakness, skin rash, itching, hypoglycemia (low blood sugar), vitamin B12 deficiency, abnormal liver function tests, lactic acidosis (rare but serious). Contact your doctor immediately if you experience symptoms of lactic acidosis, such as rapid breathing, abdominal pain, muscle cramps, and severe weakness.

Safety Advice for SITARA M 100/1000MG TABLET 10'SArrow

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Allergies

Allergies

Inform your doctor if you are allergic to this medicine or any of its ingredients.

Dosage of SITARA M 100/1000MG TABLET 10'SArrow

  • The recommended dosage of SITARA M 100/1000MG TABLET 10'S is determined by your physician based on individual factors, including your blood glucose levels, overall health, and response to treatment. It is typically prescribed to be taken orally, once or twice daily, with meals to minimize gastrointestinal side effects. The starting dose may vary, but it often begins with one tablet per day, which may be gradually adjusted by your doctor to achieve optimal blood sugar control. It's crucial to adhere strictly to the prescribed dosage and timing. Do not exceed the recommended dose or discontinue the medication without consulting your healthcare provider.
  • Consistency is key to the effectiveness of SITARA M 100/1000MG TABLET 10'S. Taking the tablet at the same time(s) each day helps maintain a steady level of medication in your bloodstream, leading to better blood sugar control. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Avoid doubling the dose to compensate for a missed one, as this can increase the risk of side effects.
  • Regular monitoring of your blood glucose levels is essential while taking SITARA M 100/1000MG TABLET 10'S. This helps you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Your doctor may also recommend periodic blood tests to monitor your kidney function and vitamin B12 levels, as metformin can sometimes affect these parameters. Always follow your doctor's instructions regarding blood glucose monitoring and blood tests.
  • Take 'SITARA M 100/1000MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of SITARA M 100/1000MG TABLET 10'S?Arrow

  • If you miss a dose of SITARA M 100/1000MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store SITARA M 100/1000MG TABLET 10'S?Arrow

  • Keep SITARA M 100/1000MG TAB 1X10 away from the reach of children and pets.
  • Store SITARA M 100/1000MG TAB 1X10 at room temperature.

Benefits of SITARA M 100/1000MG TABLET 10'SArrow

  • SITARA M 100/1000MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when used along with diet and exercise. By effectively managing blood sugar levels, SITARA M helps reduce the risk of serious diabetes-related complications such as kidney damage, nerve problems, loss of limbs, and sexual function problems. It can also lower the chances of heart attack or stroke.
  • The medication works through multiple mechanisms to achieve optimal blood sugar regulation. Sitagliptin, a component of SITARA M, enhances the levels of incretin hormones in the body. These hormones stimulate the release of insulin from the pancreas after meals and reduce the amount of glucose produced by the liver. Metformin, the other active ingredient, primarily decreases glucose production in the liver and improves the body's sensitivity to insulin, allowing cells to utilize glucose more effectively. This dual action helps to maintain stable blood sugar levels throughout the day.
  • One of the key benefits of SITARA M is its ability to provide comprehensive glycemic control. It addresses both fasting and postprandial (after-meal) blood sugar spikes, ensuring a more consistent and balanced glucose profile. This is particularly important for individuals who struggle to manage blood sugar fluctuations with diet and exercise alone. The combined action of sitagliptin and metformin provides a synergistic effect, resulting in better overall blood sugar management compared to using either medication alone.
  • SITARA M also offers the convenience of a single tablet, making it easier for patients to adhere to their prescribed treatment regimen. This can improve compliance and ultimately lead to better health outcomes. It is typically taken once or twice daily with meals, as directed by your doctor. Consistent use of SITARA M, in conjunction with a healthy lifestyle, is crucial for achieving and maintaining optimal blood sugar control and reducing the risk of long-term complications associated with diabetes.
  • In addition to its primary function of managing blood sugar, SITARA M may also contribute to weight management in some individuals. Metformin, in particular, has been associated with modest weight loss or weight stabilization. While SITARA M is not specifically prescribed for weight loss, its impact on glucose metabolism can indirectly support healthy weight management efforts. However, it is important to note that individual results may vary.
  • Patients taking SITARA M should be aware of potential side effects, such as nausea, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). These side effects are generally mild and transient. However, it is important to consult with your doctor if you experience any persistent or bothersome side effects. Regular monitoring of kidney function is also recommended, particularly in elderly patients or those with pre-existing kidney problems.
  • Overall, SITARA M 100/1000MG TABLET 10'S provides a multifaceted approach to managing type 2 diabetes. Its dual mechanism of action, combined with the convenience of a single tablet, makes it a valuable tool for achieving and maintaining optimal blood sugar control. When used in conjunction with a healthy lifestyle, SITARA M can help reduce the risk of serious diabetes-related complications and improve overall health and well-being. Always follow your doctor's instructions and attend regular check-ups to ensure the safe and effective use of this medication.
  • It is essential to remember that SITARA M is just one component of a comprehensive diabetes management plan. A healthy diet, regular exercise, and consistent monitoring of blood sugar levels are also crucial for achieving optimal outcomes. Work closely with your healthcare team to develop a personalized diabetes management plan that meets your individual needs and goals.

How to use SITARA M 100/1000MG TABLET 10'SArrow

  • SITARA M 100/1000MG TABLET 10'S should be taken orally, as directed by your doctor. It is typically prescribed as part of a comprehensive diabetes management plan that includes diet and exercise. To maximize its effectiveness and minimize potential side effects, adhere to the following guidelines:
  • 1. **Dosage and Timing:** Take SITARA M 100/1000MG TABLET 10'S with food, preferably at the same time each day. This helps maintain consistent blood sugar levels and reduces the risk of stomach upset. The specific dosage will be determined by your doctor based on your individual needs and response to treatment. Do not exceed the prescribed dose.
  • 2. **Swallowing the Tablet:** Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. If you have difficulty swallowing pills, discuss this with your doctor or pharmacist; they may be able to suggest alternative formulations or techniques.
  • 3. **Consistency is Key:** It's crucial to take SITARA M 100/1000MG TABLET 10'S regularly, even if you feel well. Missing doses can lead to fluctuations in blood sugar levels and may worsen your diabetes control. Use a pill organizer or set a reminder to help you stay on track.
  • 4. **Diet and Exercise:** Continue to follow the diet and exercise plan recommended by your doctor or diabetes educator. SITARA M 100/1000MG TABLET 10'S works best when combined with a healthy lifestyle. Be mindful of your carbohydrate intake and engage in regular physical activity.
  • 5. **Monitoring Blood Sugar:** Regularly monitor your blood sugar levels as directed by your doctor. This will help you and your healthcare team assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • 6. **Potential Side Effects:** Be aware of potential side effects, such as nausea, diarrhea, or abdominal discomfort. If you experience any severe or persistent side effects, contact your doctor immediately. Rarely, metformin (one of the components of SITARA M) can cause a serious side effect called lactic acidosis. Seek immediate medical attention if you develop symptoms such as rapid breathing, muscle pain, or unusual tiredness.
  • 7. **Drug Interactions:** Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with SITARA M 100/1000MG TABLET 10'S. Certain medications, such as diuretics or corticosteroids, can affect blood sugar levels.
  • 8. **Storage:** Store SITARA M 100/1000MG TABLET 10'S at room temperature, away from moisture and heat. Keep out of reach of children.
  • 9. **Consult Your Doctor:** Do not stop taking SITARA M 100/1000MG TABLET 10'S without consulting your doctor. If you have any questions or concerns about your medication, talk to your healthcare provider.

Quick Tips for SITARA M 100/1000MG TABLET 10'SArrow

  • Take SITARA M 100/1000MG TABLET as prescribed by your doctor. This medication combines two active ingredients to help manage blood sugar levels effectively in individuals with type 2 diabetes. Adhering to your doctor's instructions ensures optimal results and minimizes the risk of side effects.
  • It is crucial to take SITARA M 100/1000MG TABLET at the same time each day. Consistency in timing helps maintain a steady level of medication in your bloodstream, leading to better blood sugar control. Set a daily reminder to help you remember.
  • SITARA M 100/1000MG TABLET works best when combined with a healthy lifestyle. This includes a balanced diet, regular physical activity, and weight management. These lifestyle modifications enhance the effectiveness of the medication and contribute to overall well-being.
  • Be aware of potential side effects such as nausea, diarrhea, or stomach upset. If these side effects persist or worsen, consult your doctor immediately. Do not attempt to self-treat or discontinue the medication without medical advice.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider while taking SITARA M 100/1000MG TABLET. This helps you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Keep a record of your blood sugar readings to share with your doctor during appointments.

Food Interactions with SITARA M 100/1000MG TABLET 10'SArrow

  • It is advisable to take SITARA M 100/1000MG TABLET 10'S with food to minimize the risk of stomach upset. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a serious side effect.

FAQs

What is the use of Sitara M 100/1000mg Tablet?Arrow

Sitara M 100/1000mg Tablet is used to treat type 2 diabetes mellitus, particularly when diet and exercise alone are not enough to control blood sugar levels.

What are the active ingredients in Sitara M 100/1000mg Tablet?Arrow

Sitara M 100/1000mg Tablet contains the active ingredients Sitagliptin (100mg) and Metformin (1000mg).

What are the common side effects of Sitara M 100/1000mg Tablet?Arrow

Common side effects of Sitara M 100/1000mg Tablet include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is Sitara M 100/1000mg Tablet safe for patients with kidney problems?Arrow

Sitara M 100/1000mg Tablet is not recommended for patients with kidney problems, as it can increase the risk of lactic acidosis.

Should Sitara M 100/1000mg Tablet be taken with food?Arrow

It is recommended to take Sitara M 100/1000mg Tablet with food to avoid stomach upset.

How should Sitara M 100/1000mg Tablet be stored?Arrow

Sitara M 100/1000mg Tablet should be stored at room temperature, away from direct sunlight and moisture.

Can Sitara M 100/1000mg Tablet interact with other medications?Arrow

Sitara M 100/1000mg Tablet can interact with certain medications, such as insulin, sulfonylureas, and some antibiotics. It is important to inform your doctor about all the medications you are taking to avoid any potential interactions.

What are the symptoms of an overdose of Sitara M 100/1000mg Tablet?Arrow

Symptoms of an overdose of Sitara M 100/1000mg Tablet may include nausea, vomiting, abdominal pain, dizziness, and in severe cases, lactic acidosis.

Can pregnant women take Sitara M 100/1000mg Tablet?Arrow

Sitara M 100/1000mg Tablet is not recommended for pregnant women. Consult your doctor if you are pregnant or planning to become pregnant.

Can breastfeeding women take Sitara M 100/1000mg Tablet?Arrow

Sitara M 100/1000mg Tablet is not recommended for breastfeeding women. Consult your doctor if you are breastfeeding.

Does Sitara M 100/1000mg Tablet cause weight gain?Arrow

Sitara M 100/1000mg Tablet does not typically cause weight gain. In fact, some people may experience slight weight loss with it.

Can I drink alcohol while taking Sitara M 100/1000mg Tablet?Arrow

It is not recommended to drink alcohol while taking Sitara M 100/1000mg Tablet, as it can increase the risk of lactic acidosis.

How long does it take for Sitara M 100/1000mg Tablet to start working?Arrow

It may take a few days for Sitara M 100/1000mg Tablet to start working. It may take several weeks to see a noticeable improvement in your blood sugar levels.

Can Sitara M 100/1000mg Tablet be crushed?Arrow

Sitara M 100/1000mg Tablet should be swallowed whole and not broken, crushed, or chewed.

What happens if I miss a dose of Sitara M 100/1000mg Tablet?Arrow

If you miss a dose of Sitara M 100/1000mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

References

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FDA (Food and Drug Administration) Label for Metformin Hydrochloride. This document provides detailed information on the drug, including its uses, dosage, side effects, and contraindications. Metformin is a common ingredient in SITARA M tablets.

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A Study of the Safety and Efficacy of Metformin ER in Patients with Type 2 Diabetes Mellitus. Published in Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. This research article discusses the effectiveness and safety of extended-release metformin, which may be relevant depending on the specific formulation of SITARA M.

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DrugBank entry for Metformin. This database provides comprehensive information about metformin, including its mechanism of action, pharmacokinetics, and interactions.

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Efficacy and safety of metformin in polycystic ovary syndrome: a systematic review and meta-analysis. This study published in the Journal of Clinical Endocrinology & Metabolism examines the effects of metformin in women with PCOS.

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European Medicines Agency (EMA) information on metformin-containing medicinal products. This provides regulatory information and scientific assessment reports related to metformin.

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