SPENZO 0.5MG TABLET 10'S
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SPENZO 0.5MG TABLET 10'SSPENZO 0.5MG TABLET 10'SSPENZO 0.5MG TABLET 10'SSPENZO 0.5MG TABLET 10'S
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SPENZO 0.5MG TABLET 10'S

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SPENZO 0.5MG TABLET 10'S

By INTAS PHARMACEUTICALS LIMITED

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55.31

₹47.01

15.01 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Manoj Shah

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About SPENZO 0.5MG TABLET 10'S

  • Spenzo 0.5 is a branded formulation that contains flupentixol hydrochloride 0.5 mg, a typical antipsychotic medicine from the thioxanthene group. At this low strength, it is generally used under specialist supervision for the management of certain mood and anxiety-related conditions, and sometimes as part of treatment plans for psychotic disorders. The exact approved indications can vary by country and regulatory authority, so patients should rely on the advice of their prescribing psychiatrist or physician and the locally approved product information. Flupentixol acts primarily by blocking dopamine D2 receptors in the brain. This modulation of dopamine transmission can help reduce symptoms such as excessive worry, agitation, tension, and certain psychotic features like hallucinations or delusional thinking. At low doses, flupentixol is often used for its activating and mood-stabilising properties in selected patients with depressive or anxiety symptoms, while at higher doses it is used as an antipsychotic. Spenzo 0.5 should only be started, adjusted, or stopped by a qualified healthcare professional familiar with antipsychotic medicines. The tablets are usually taken by mouth with water, with or without food, at the same time each day to maintain stable blood levels. The appropriate regimen depends on the individual’s diagnosis, age, other medications, and response to treatment. Because dosing must be individualised, patients should strictly follow the prescription label and not change the dose or frequency on their own. If a dose is missed, the patient should follow the instructions given by their doctor or pharmacist rather than doubling the next dose. Commonly reported adverse effects of flupentixol include drowsiness or sedation, dizziness, dry mouth, constipation, increased salivation, blurred vision, restlessness, and weight changes. Extrapyramidal symptoms (movement-related side effects) such as muscle stiffness, tremor, or a feeling of inner restlessness (akathisia) can occur, especially at higher doses or in susceptible individuals. Rare but serious adverse reactions include neuroleptic malignant syndrome (characterised by high fever, severe muscle rigidity, confusion, and autonomic instability), significant changes in heart rhythm, seizures, and severe allergic reactions. Any sudden change in mental state, high fever, muscle stiffness, or uncontrollable movements requires urgent medical attention. Spenzo 0.5 may interact with other medicines that affect the central nervous system, such as other antipsychotics, antidepressants, sedatives, opioid analgesics, antihistamines with sedative properties, and alcohol. It can also interact with medicines that influence heart rhythm (for example, some antiarrhythmics, macrolide antibiotics, or certain antidepressants) and with drugs that alter blood pressure. Patients should provide their doctor with a complete list of all prescription medicines, over-the-counter products, and herbal supplements before starting Spenzo 0.5. Use in special populations requires caution. In elderly patients, there may be an increased risk of sedation, falls, low blood pressure, and movement disorders. In individuals with liver or kidney impairment, dose adjustments or closer monitoring may be necessary because flupentixol is metabolised in the liver and excreted partly via the kidneys. Patients with a history of seizures, cardiovascular disease, prolonged QT interval, glaucoma, or blood disorders should inform their doctor before using this medicine. Spenzo 0.5 is not intended for mild, self-limiting mood changes or routine stress. It is a prescription-only medicine that should be used as part of a comprehensive treatment plan, which may include psychological therapies and lifestyle measures. Regular follow-up appointments are important to assess symptom control, monitor side effects, and decide whether any dose changes or additional investigations (such as blood tests or ECG) are needed. Patients should not stop Spenzo 0.5 abruptly unless instructed, as sudden discontinuation may lead to withdrawal-like symptoms or relapse of the underlying condition.

Uses of SPENZO 0.5MG TABLET 10'S

  • Schizophrenia is a chronic brain disorder that affects a person's ability to think, feel, and behave clearly.
  • Depression is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. It can be treated with medications like SPENZO 0.5MG TABLET 10'S.
  • Bipolar disorder is a mental disorder that causes unusual shifts in mood, energy, activity levels, concentration, and the ability to carry out day-to-day tasks.

How SPENZO 0.5MG TABLET 10'S Works

  • SPENZO 0.5MG TABLET 10'S is a medication classified as a typical antipsychotic. It functions primarily by influencing the activity of dopamine, a crucial neurotransmitter within the brain. Neurotransmitters like dopamine are responsible for transmitting signals between nerve cells, thereby playing a significant role in various brain functions, including mood regulation, emotional responses, and cognitive processes.
  • Specifically, SPENZO 0.5MG TABLET 10'S works by blocking dopamine receptors in the brain. These receptors are like docking stations that dopamine molecules bind to in order to exert their effects. By blocking these receptors, the medication reduces the amount of dopamine that can bind and stimulate them. This action helps to modulate dopamine activity, which is often overactive in certain mental health conditions.
  • By reducing the overactivity of dopamine, SPENZO 0.5MG TABLET 10'S can help alleviate symptoms associated with conditions like psychosis, such as hallucinations (seeing or hearing things that are not real), delusions (false beliefs), and disorganized thinking. It helps in stabilizing mood, reducing agitation, and improving overall mental clarity. This leads to an improvement in daily functioning and quality of life for individuals experiencing these challenging symptoms.

Side Effects of SPENZO 0.5MG TABLET 10'SArrow

Most side effects are temporary and subside as your body adapts to SPENZO 0.5MG TABLET 10'S. However, consult your doctor if they persist or cause concern.

  • Sleepiness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dryness in mouth
  • Abnormality of voluntary movements
  • Weight gain
  • Increased prolactin level in blood
  • Urinary retention
  • Constipation
  • Muscle stiffness
  • Tremors

Safety Advice for SPENZO 0.5MG TABLET 10'SArrow

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Other medical conditions

Use under specialist supervision

Spenzo 0.5 should be used with particular caution in patients with a history of cardiovascular disease, arrhythmias, prolonged QT interval, or those taking other medicines that affect heart rhythm, as antipsychotics can in some cases influence cardiac conduction.

How to store SPENZO 0.5MG TABLET 10'S?Arrow

  • Keep SPENZO 0.5MG TAB 1X10 away from the reach of children and pets.
  • Store SPENZO 0.5MG TAB 1X10 at room temperature.

Benefits of SPENZO 0.5MG TABLET 10'SArrow

  • <b>Schizophrenia</b><br>SPENZO 0.5MG TABLET 10'S is used to manage Schizophrenia. Schizophrenia is a complex mental disorder that disrupts a person's thinking, emotions, and behavior. SPENZO 0.5MG TABLET 10'S assists in re-establishing the balance of chemical messengers within the brain, which are often imbalanced in individuals with schizophrenia. By regulating these chemicals, SPENZO 0.5MG TABLET 10'S can lead to improvements in thought processes, mood stability, and overall behavior, significantly enhancing the patient's quality of life. Regular use as prescribed by a healthcare professional is crucial for managing symptoms effectively. It is often used alongside other therapeutic interventions such as counseling and support groups to ensure a holistic approach to schizophrenia management.
  • <b>Depression</b><br>SPENZO 0.5MG TABLET 10'S can be an effective component in the management of depression. Depression often stems from an imbalance of specific chemicals in the brain, which profoundly affects a person’s mood and behavior. SPENZO 0.5MG TABLET 10'S contributes to restoring this balance, leading to an improved mood, reduced anxiety and tension, better sleep patterns, and increased energy levels. SPENZO 0.5MG TABLET 10'S helps stabilize mood fluctuations and reduces feelings of agitation, leading to a decrease in the frequency and intensity of depressive episodes. Consistent adherence to the prescribed dosage, combined with therapy and lifestyle adjustments, can help patients achieve significant improvements in their mental well-being.
  • <b>Bipolar disorder</b><br>SPENZO 0.5MG TABLET 10'S plays a vital role in managing bipolar disorder by working to restore the normal balance of nerve activity within the brain. Bipolar disorder is characterized by extreme shifts in mood, from manic highs to depressive lows. SPENZO 0.5MG TABLET 10'S helps in preventing these drastic mood swings and reduces feelings of agitation, thereby stabilizing the patient's emotional state. While it may take several weeks for the medication to take full effect, consistent and regular use is essential for optimal results. Patients typically require long-term treatment, often extending beyond six months, and should not discontinue the medication without consulting their doctor. In addition to medication, maintaining a healthy lifestyle through proper nutrition and regular exercise is important for managing the symptoms of bipolar disorder.

How to use SPENZO 0.5MG TABLET 10'SArrow

  • Always adhere to your doctor's instructions regarding the dosage and duration of SPENZO 0.5MG TABLET 10'S. This medication should be swallowed whole with a glass of water; avoid chewing, crushing, or breaking the tablet, as this can affect how the medicine is absorbed into your system. Maintaining a consistent routine is important for optimal results. You can take SPENZO 0.5MG TABLET 10'S either with or without food. However, for the best possible outcome, it's recommended to take it at the same time each day. This helps maintain a steady level of the medication in your bloodstream, maximizing its effectiveness. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • If you have any concerns or questions about how to properly take SPENZO 0.5MG TABLET 10'S, it's crucial to consult your doctor or pharmacist for clarification. They can provide personalized guidance based on your specific health condition and any other medications you may be taking. Never adjust the dosage or discontinue the medication without first seeking professional medical advice, as this could lead to undesirable side effects or a worsening of your condition.

Quick Tips for SPENZO 0.5MG TABLET 10'SArrow

  • Take SPENZO 0.5MG TABLET 10'S at bedtime to minimize daytime sleepiness. This medication can cause dizziness and drowsiness, so exercise caution when driving or operating machinery that requires focus. Avoid alcohol consumption while taking SPENZO 0.5MG TABLET 10'S, as it can exacerbate drowsiness. It's important to inform your doctor immediately if you notice any unusual movements, especially involving your face, lips, jaw, or tongue. SPENZO 0.5MG TABLET 10'S may lead to weight gain, increased blood sugar, and elevated cholesterol levels. Maintain a healthy diet, engage in regular exercise, and monitor your blood levels periodically. Do not discontinue SPENZO 0.5MG TABLET 10'S without consulting your doctor, as abrupt cessation may worsen your symptoms. This medication works best when taken consistently as prescribed. If you experience any concerning side effects or have questions, promptly contact your healthcare provider for guidance. Remember that individual responses to medication can vary, so open communication with your doctor is key to ensuring safe and effective treatment. Regular check-ups can help monitor your progress and address any potential issues that may arise. Adhering to your doctor's instructions and maintaining a healthy lifestyle are crucial components of managing your condition effectively while taking SPENZO 0.5MG TABLET 10'S.
  • To ensure optimal results, take SPENZO 0.5MG TABLET 10'S consistently at the same time each day, preferably at bedtime. This helps establish a regular pattern and maximizes the medication's effectiveness in managing your symptoms. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one. Maintain a log of your symptoms and any side effects you experience while taking SPENZO 0.5MG TABLET 10'S. This information can be valuable for your doctor in assessing your progress and making any necessary adjustments to your treatment plan. Store SPENZO 0.5MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. If you have any questions or concerns about storing or disposing of your medication, consult your pharmacist for guidance. By following these additional precautions, you can help ensure the safe and effective use of SPENZO 0.5MG TABLET 10'S and optimize your treatment outcomes.
  • While taking SPENZO 0.5MG TABLET 10'S, be mindful of potential interactions with other medications or supplements you may be taking. Certain substances can affect how SPENZO 0.5MG TABLET 10'S works, either increasing or decreasing its effectiveness or increasing the risk of side effects. It's essential to inform your doctor about all the medications, vitamins, and herbal supplements you are currently taking to avoid any potential interactions. Some common substances that may interact with SPENZO 0.5MG TABLET 10'S include alcohol, antihistamines, and certain antidepressants. Your doctor can provide specific guidance on which substances to avoid or use with caution while taking SPENZO 0.5MG TABLET 10'S. If you experience any unexpected symptoms or changes in your condition after starting or stopping other medications, notify your doctor promptly. By being proactive about potential interactions and communicating openly with your healthcare provider, you can minimize the risk of adverse effects and ensure the safe and effective use of SPENZO 0.5MG TABLET 10'S.

FAQs

<h3 class=bodySemiBold>What is SPENZO 0.5MG TABLET 10'S deconate?</h3>Arrow

SPENZO 0.5MG TABLET 10'S belongs to a class of medication called as typical antipsychotic. It acts by increasing the amounts of chemical (serotonin), in the brain. SPENZO 0.5MG TABLET 10'S decanoate is a long-acting preparation of SPENZO 0.5MG TABLET 10'S for injection into the muscles, which may be given at a frequency ranging from once in a week to once in 4 weeks

<h3 class=bodySemiBold>What is SPENZO 0.5MG TABLET 10'S used for?</h3>Arrow

SPENZO 0.5MG TABLET 10'S is used in the treatment of schizophrenia and other psychoses which are disorders where individuals are unable to distinguish between what is real and unreal, think clearly, manage emotions, relate to others, and function normally

<h3 class=bodySemiBold>Why is SPENZO 0.5MG TABLET 10'S banned?</h3>Arrow

SPENZO 0.5MG TABLET 10'S in combination with melitracen is banned in india due to safety concern

<h3 class=bodySemiBold>How does SPENZO 0.5MG TABLET 10'S work?</h3>Arrow

SPENZO 0.5MG TABLET 10'S belongs to a class of medication called as typical antipsychotic. It acts by normalizing the levels of certain chemicals in the brain in specific brain pathways that are responsible for causing symptoms of the disease.

What is Spenzo 0.5 and what does it contain?Arrow

Spenzo 0.5 is a prescription medicine that contains flupentixol hydrochloride 0.5 mg, a typical antipsychotic from the thioxanthene class. At this low strength, it is generally used under specialist supervision for certain mood and anxiety-related conditions and, in some settings, as part of treatment for psychotic disorders. The exact approved uses may differ between countries, so patients should follow the advice of their local healthcare provider and the product leaflet.

What is Spenzo 0.5 used for?Arrow

Spenzo 0.5 is typically prescribed by psychiatrists or physicians for selected patients with depressive or anxiety symptoms, sometimes when these are accompanied by agitation, tension, or other features that may respond to low-dose flupentixol. In some treatment plans it may also be used as part of therapy for psychotic disorders. The indication for an individual patient should be clearly explained by the treating doctor, based on local regulatory approvals and clinical judgement.

How does flupentixol in Spenzo 0.5 work in the body?Arrow

Flupentixol primarily blocks dopamine D2 receptors in the brain. By reducing excessive dopaminergic activity in certain pathways, it can help improve symptoms such as agitation, anxiety, and psychotic features like hallucinations or delusions. At low doses, it may have a relatively activating and mood-stabilising effect in some patients, while at higher doses it behaves more as a conventional antipsychotic. The full therapeutic effect may take several days to a few weeks to become evident.

How should I take Spenzo 0.5?Arrow

Spenzo 0.5 should be taken exactly as prescribed by your doctor, usually by mouth with water, with or without food. It is important to take it at the same time each day to maintain stable levels in your body. Do not change the dose, frequency, or duration of treatment on your own. If you are unsure about how to take the medicine or what to do if you miss a dose, ask your doctor or pharmacist for personalised instructions. Do not crush or split the tablet unless your doctor or the product leaflet specifically allows this.

What are the common side effects of Spenzo 0.5?Arrow

Common side effects associated with flupentixol include drowsiness or sedation, dizziness, dry mouth, constipation, increased salivation, blurred vision, restlessness, and weight changes. Some patients may experience movement-related symptoms such as muscle stiffness, tremor, or a feeling of inner restlessness (akathisia). Not everyone will experience these effects, and many are mild and may lessen as treatment continues. If side effects are persistent, troublesome, or worsening, you should discuss them with your doctor.

Can Spenzo 0.5 cause serious adverse reactions?Arrow

Yes, although serious reactions are uncommon, they can occur and require urgent medical attention. These include neuroleptic malignant syndrome (characterised by high fever, severe muscle rigidity, confusion, sweating, and unstable blood pressure or heart rate), severe extrapyramidal symptoms or uncontrollable movements, seizures, significant changes in heart rhythm, and severe allergic reactions such as swelling of the face or throat and difficulty breathing. If you develop any of these symptoms, or a sudden marked change in mental state, seek emergency medical care immediately.

Is Spenzo 0.5 habit-forming or addictive?Arrow

Flupentixol is not considered a habit-forming or addictive medicine in the way that benzodiazepines, opioids, or some sedative drugs can be. However, it acts on the central nervous system, and stopping it suddenly after prolonged use may lead to withdrawal-like symptoms such as nausea, sleep disturbance, restlessness, or a return or worsening of the underlying psychiatric condition. For this reason, any change in dose or discontinuation should be done gradually and only under medical supervision.

Can I drink alcohol while taking Spenzo 0.5?Arrow

Alcohol is generally not recommended while taking Spenzo 0.5. Both alcohol and flupentixol act on the central nervous system and can increase drowsiness, dizziness, impaired coordination, and judgement. This combination may raise the risk of falls, accidents, or other adverse effects. Alcohol can also worsen underlying psychiatric symptoms in some individuals. If you consume alcohol, discuss this with your doctor so that you can receive personalised advice and monitoring.

What should I do if I miss a dose of Spenzo 0.5?Arrow

If you miss a dose, follow the instructions provided by your doctor or pharmacist. In general, if it is only a short time after the scheduled dose, you may be advised to take it as soon as you remember. If it is almost time for your next dose, you may be told to skip the missed dose and resume your usual schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently forget doses, inform your doctor so that strategies can be discussed.

Can I stop taking Spenzo 0.5 once I feel better?Arrow

You should not stop Spenzo 0.5 on your own, even if you feel better. Psychiatric symptoms can recur if treatment is stopped too early or abruptly. Your doctor will decide how long you need to continue therapy based on your diagnosis, response, and risk of relapse. When it is appropriate to stop, the dose is usually reduced gradually to minimise withdrawal-like symptoms and to monitor for any return of the underlying condition. Always follow your doctor’s instructions regarding treatment duration.

Does Spenzo 0.5 interact with other medicines?Arrow

Yes, Spenzo 0.5 can interact with several other medicines. Interactions may occur with other antipsychotics, antidepressants, sedatives, opioid painkillers, antihistamines that cause drowsiness, medicines that affect heart rhythm (such as some antiarrhythmics and certain antibiotics), and drugs that lower blood pressure. Some medicines that influence liver enzymes may also affect flupentixol levels. Always inform your doctor and pharmacist about all prescription medicines, over-the-counter products, and herbal supplements you are taking before starting Spenzo 0.5.

References

Book Icon

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Flupenthixol. [Updated 2018 Dec 3]. (online) Available from:

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Flupenthixol. Everard Close, Abbey View St Albans: Lundbeck Limited; 1982 [revised Dec. 2016]. (online) Available from:

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Central Drugs Standard Control Organisation (CDSCO). (online) Available from:

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