SUBACT 1 GM INJECTION

How SUBACT 1 GM INJECTION Works

• SUBACT 1 GM INJECTION is a powerful combination antibiotic containing sulbactam and cefoperazone. This dual-action medication combats bacterial infections through two distinct mechanisms, providing a synergistic effect that enhances its overall efficacy. Cefoperazone, a cephalosporin antibiotic, disrupts bacterial cell wall synthesis. Bacteria, like all cells, require a cell wall for structural integrity and survival. Cefoperazone specifically targets and binds to penicillin-binding proteins (PBPs) located within the bacterial cell wall. These PBPs are enzymes crucial for the construction and cross-linking of peptidoglycans, the essential building blocks of the cell wall. By binding to PBPs, cefoperazone inhibits their activity, preventing the proper formation of peptidoglycan layers. This leads to a weakened and unstable cell wall.
• As the bacteria attempt to grow and divide, the compromised cell wall cannot withstand internal pressure, ultimately leading to cell lysis (rupture) and bacterial death. Cefoperazone exhibits a broad spectrum of activity against a wide range of Gram-positive and Gram-negative bacteria, making it effective against various types of infections.
• Sulbactam, a beta-lactamase inhibitor, plays a crucial role in protecting cefoperazone from enzymatic degradation. Many bacteria produce enzymes called beta-lactamases, which can break down beta-lactam antibiotics like cefoperazone, rendering them ineffective. Sulbactam acts as a 'decoy' molecule, binding to beta-lactamases and preventing them from inactivating cefoperazone. By inhibiting beta-lactamase, sulbactam ensures that cefoperazone remains active and can effectively target bacterial cell walls. This combination is particularly useful in treating infections caused by bacteria that produce beta-lactamases, as it overcomes the resistance mechanism that would otherwise limit the antibiotic's effectiveness.
• The combined action of cefoperazone and sulbactam provides a potent antibacterial effect. Cefoperazone directly inhibits bacterial cell wall synthesis, while sulbactam protects cefoperazone from degradation by bacterial enzymes. This synergistic combination broadens the spectrum of activity and enhances the overall efficacy of SUBACT 1 GM INJECTION against a wide range of bacterial infections.

Like all medicines, SUBACT 1 GM INJECTION can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Pain at the injection site * Redness * Swelling * Diarrhea * Nausea **Uncommon side effects (may affect up to 1 in 100 people):** * Vomiting * Rash * Itching * Hives * Headache * Dizziness * Increased liver enzymes * Increased creatinine * Thrombophlebitis (inflammation of a vein with a blood clot) **Rare side effects (may affect up to 1 in 1,000 people):** * Abdominal pain * Jaundice (yellowing of the skin or eyes) * Anaphylactic reaction (severe allergic reaction) * Stevens-Johnson syndrome (a rare, serious skin disorder) * Toxic epidermal necrolysis (a severe form of Stevens-Johnson syndrome) * Blood disorders (such as anemia, leukopenia, thrombocytopenia) * Kidney problems * Clostridium difficile-associated diarrhea (CDAD) - causing watery or bloody stools **Very rare side effects (may affect up to 1 in 10,000 people):** * Seizures **Important Information:** This is not a complete list of side effects. If you experience any unusual symptoms after receiving SUBACT 1 GM INJECTION, consult your doctor or pharmacist immediately.

• If you miss a dose of SUBACT 1 GM Injection, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
• Contact your doctor immediately for further guidance.

• Keep SUBACT 1GM INJ away from the reach of children and pets.
• Store SUBACT 1GM INJ at room temperature.

• Complete the Full Course: Even if you feel better after a few doses, finish the entire course of SUBACT 1 GM INJECTION as prescribed by your doctor. Stopping early may allow the infection to return and become harder to treat.
• Administered by Healthcare Professional: SUBACT 1 GM INJECTION must be administered by a trained healthcare professional. Do not attempt to self-administer this medication.
• Inform Your Doctor of Allergies: Before receiving SUBACT 1 GM INJECTION, inform your doctor if you are allergic to any penicillins, cephalosporins, or other antibiotics. Allergic reactions can be severe.
• Monitor for Side Effects: Watch out for common side effects such as pain or swelling at the injection site, nausea, or diarrhea. If these persist or worsen, consult your doctor immediately. Report any severe reactions like rash, itching, or difficulty breathing right away.
• Maintain Hydration: Drink plenty of fluids while you are receiving SUBACT 1 GM INJECTION. Staying hydrated helps your body process the medication and can alleviate some side effects. Discuss any concerns you have with your healthcare provider.
• Inform your doctor about any other medications or supplements you are currently taking. Subact can interact with other drugs, potentially affecting their effectiveness or increasing the risk of side effects. This includes over-the-counter medications and herbal remedies.
• If you experience any signs of an allergic reaction, such as hives, itching, swelling, or difficulty breathing, seek immediate medical attention. Allergic reactions to antibiotics can be severe and require prompt treatment.
• Subact may cause diarrhea as a side effect. If you develop severe or persistent diarrhea, especially if it contains blood or mucus, contact your doctor. This could be a sign of a more serious condition called Clostridium difficile-associated diarrhea (CDAD).
• For women, it's important to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting Subact treatment. The medication's potential effects on the fetus or infant should be carefully considered.
• Store Subact according to the instructions provided by the pharmacist or healthcare professional. Typically, it should be kept in a cool, dry place away from direct sunlight and moisture. Proper storage helps maintain the medication's effectiveness and safety.

• SUBACT 1 GM INJECTION is administered intravenously or intramuscularly and does not typically interact with food. It is usually given by a healthcare professional in a clinical setting, so dietary considerations are generally not a concern. Continue with your regular diet unless your doctor advises otherwise.