SYNRIAM 150+750MG TABLET 3'S

How SYNRIAM 150+750MG TABLET 3'S Works

• SYNRIAM 150+750MG TABLET 3'S is a combination medication containing two active ingredients: Rifampicin and Isoniazid. These medications work synergistically to combat Mycobacterium tuberculosis, the bacteria responsible for tuberculosis (TB). Understanding how each component functions is crucial to appreciating the overall efficacy of SYNRIAM.
• Rifampicin is a potent antibiotic that inhibits bacterial RNA synthesis. Specifically, it binds to bacterial DNA-dependent RNA polymerase, an enzyme essential for transcribing DNA into RNA. By binding to this enzyme, Rifampicin prevents the bacteria from producing the RNA necessary for synthesizing proteins and replicating. This action effectively halts bacterial growth and leads to bacterial cell death. Rifampicin's broad-spectrum activity also makes it effective against some other bacteria, but its primary use is in treating TB.
• Isoniazid, on the other hand, targets the synthesis of mycolic acids, which are crucial components of the mycobacterial cell wall. Mycolic acids provide a protective barrier around the bacteria, making them resistant to many antibiotics and environmental stresses. Isoniazid inhibits the enzyme InhA, which is involved in the synthesis of these mycolic acids. By disrupting mycolic acid production, Isoniazid weakens the bacterial cell wall, making the bacteria more vulnerable and preventing their replication.
• The combined action of Rifampicin and Isoniazid in SYNRIAM provides a two-pronged attack against TB. Rifampicin directly inhibits RNA synthesis, preventing bacterial growth, while Isoniazid weakens the bacterial cell wall, further hindering bacterial survival and replication. This synergistic effect is vital for effectively treating TB and preventing the development of drug resistance. The combination reduces the likelihood of resistance emerging compared to using either drug alone.
• Furthermore, the fixed-dose combination of SYNRIAM simplifies treatment regimens and improves patient compliance. Patients only need to take one tablet containing both medications, reducing the pill burden and increasing the likelihood of adherence to the prescribed treatment course. Consistent adherence is essential for successful TB treatment and preventing the spread of the disease.
• In summary, SYNRIAM 150+750MG TABLET 3'S works by utilizing Rifampicin to block bacterial RNA synthesis and Isoniazid to disrupt the formation of the bacterial cell wall. This dual mechanism of action effectively targets Mycobacterium tuberculosis, leading to bacterial death and preventing the spread of infection. The combination also simplifies treatment and improves patient compliance, contributing to better treatment outcomes in the fight against TB.

Common side effects of SYNRIAM 150+750MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and dyspepsia (indigestion). Less common but potentially serious side effects can include lactic acidosis (symptoms may include rapid breathing, nausea, vomiting, and abdominal pain), liver problems (such as hepatitis or liver failure), and kidney problems. Allergic reactions (rash, itching, swelling), hypoglycemia (low blood sugar), and vitamin B12 deficiency are also possible. Some patients may experience muscle pain or weakness. It is important to contact your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of SYNRIAM 150+750MG TABLET 3'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SYNRIAM 150/750MG TAB 1X3 away from the reach of children and pets.
• Store SYNRIAM 150/750MG TAB 1X3 at room temperature.

• Take SYNRIAM 150+750MG TABLET 3'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this can impact its effectiveness and increase the risk of side effects. The usual dosage is once or twice daily, but your doctor will determine the best regimen for your specific condition.
• SYNRIAM 150+750MG TABLET 3'S is typically taken with food to minimize stomach upset and improve absorption. Consistent timing, such as taking it with breakfast and dinner, can help maintain steady blood levels of the medication and optimize its therapeutic effects. Avoid taking it on an empty stomach.
• Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking before starting SYNRIAM 150+750MG TABLET 3'S. Drug interactions can occur, potentially reducing the effectiveness of SYNRIAM or increasing the risk of adverse effects. This includes over-the-counter medications and even vitamins.
• Be aware of potential side effects, such as nausea, diarrhea, headache, or dizziness. While many side effects are mild and temporary, it's important to report any persistent or severe symptoms to your doctor. They can provide guidance on managing these side effects or adjust your treatment plan if necessary. Drinking plenty of water can help with some side effects.
• Store SYNRIAM 150+750MG TABLET 3'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage helps maintain the medication's potency and prevents accidental ingestion. Do not store in the bathroom.
• If you miss a dose of SYNRIAM 150+750MG TABLET 3'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up, as this can increase the risk of side effects.
• Attend all scheduled follow-up appointments with your doctor. These appointments allow your doctor to monitor your progress, assess the effectiveness of SYNRIAM 150+750MG TABLET 3'S, and make any necessary adjustments to your treatment plan. Regular monitoring can help prevent complications and ensure the best possible outcome.
• Avoid alcohol consumption while taking SYNRIAM 150+750MG TABLET 3'S, as alcohol can interact with the medication and increase the risk of liver damage or other adverse effects. Alcohol can also worsen some of the common side effects of the medication, such as nausea and dizziness.
• Before undergoing any surgical procedures or dental work, inform your healthcare provider that you are taking SYNRIAM 150+750MG TABLET 3'S. This is important because the medication may affect blood clotting or interact with anesthesia. Your healthcare provider can provide specific instructions on how to manage your medication around the time of the procedure.
• Consult your doctor or pharmacist if you have any questions or concerns about SYNRIAM 150+750MG TABLET 3'S. They are the best resources for providing personalized advice and addressing any issues you may encounter during your treatment. Do not rely solely on information found online or from other sources.

• SYNRIAM 150+750MG TABLET 3'S can be taken with or without food. However, taking it with food may help to reduce stomach upset. Avoid consuming high-fat meals while taking this medication as it may decrease the absorption of the drug.