TEMOREL 5 CAPSULE 5'S
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TEMOREL 5 CAPSULE 5'S
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TEMOREL 5 CAPSULE 5'S

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TEMOREL 5 CAPSULE 5'S

By RELIANCE LIFE SCIENCES

MRP

600

₹480

20 % OFF

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CAPSULE

10

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Product DetailsArrow

About TEMOREL 5 CAPSULE 5'S

  • TEMOREL 5 CAPSULE 5'S contains temozolomide as its active ingredient, belonging to a class of drugs known as antitumor agents. It is primarily used in the treatment of brain cancers, specifically glioblastoma multiforme in adults, and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma, in patients over the age of three. Glioblastoma and anaplastic astrocytoma are aggressive forms of brain cancer with limited survival rates. Anaplastic astrocytoma is managed with TEMOREL 5 CAPSULE 5'S or radiotherapy post-biopsy, whereas glioblastoma multiforme is treated using a combination of radiotherapy and TEMOREL 5 CAPSULE 5'S, followed by maintenance therapy with the medication.
  • TEMOREL 5 CAPSULE 5'S works by damaging the DNA of cancer cells, which prevents them from growing and multiplying. This helps to slow down the progression of the cancer and may lead to remission in some cases. The exact mechanism of action involves alkylation of DNA, which disrupts the cancer cell's ability to replicate.
  • Common side effects associated with TEMOREL 5 CAPSULE 5'S include nausea, vomiting, dizziness, diarrhea, constipation, hair loss, skin rashes, fatigue, frequent urination, vision and hearing disturbances, elevated blood sugar levels, muscle damage, muscle and joint pain, memory impairment, coordination issues, infections, sleep disturbances, and weight loss. It is important to inform your doctor if any of these side effects become bothersome or persist. Regular monitoring by your healthcare provider is crucial to manage these potential side effects effectively.
  • Before starting treatment with TEMOREL 5 CAPSULE 5'S, it is essential to inform your doctor if you have any allergies to temozolomide or any of the other ingredients in the medication. Also, disclose any pre-existing medical conditions, such as hepatitis B infection, anemia, low platelet count, low red blood cell count, low white blood cell count, blood clotting disorders, or any liver or kidney problems. Your doctor will need to monitor your white blood cell and platelet counts regularly during treatment. This medication is contraindicated during pregnancy and breastfeeding. Both men and women should use effective birth control methods to prevent pregnancy during treatment and for a period after the last dose.

Uses of TEMOREL 5 CAPSULE 5'S

  • Management of newly diagnosed glioblastoma multiforme, focusing on comprehensive treatment strategies.
  • Therapeutic intervention for refractory anaplastic astrocytoma, addressing cases that are unresponsive to standard treatments.

Side Effects of TEMOREL 5 CAPSULE 5'SArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. TEMOREL 5 CAPSULE 5'S can cause serious side effects like secondary cancer (myelodysplastic syndrome and myeloid leukemia), severe allergic reactions, lung inflammation and fluid buildup, blood clots in the lungs or legs, liver toxicity, convulsions, fever and chills, severe headache, and uncontrolled bleeding. Common side effects include hair loss, rashes, tiredness, nausea, vomiting and diarrhea, constipation, high blood sugar levels, dizziness, impaired sensation, tingling, abnormal taste, vision and hearing problems, frequent urination, muscle damage, muscle and joint pain, weight changes, infections and wounds, amnesia, abnormal blood cell counts, loss of appetite, sleep problems, memory loss, difficulty concentrating, changes in mental status and alertness and coordination problems.

  • Secondary cancer like myelodysplastic syndrome and myeloid leukemia.
  • Severe Allergic reactions
  • Inflammation and fluid buildup in lungs
  • Blood clot in lungs or legs
  • Liver toxicity
  • Convulsions
  • Fever and chills
  • Severe headache
  • Uncontrolled bleeding
  • Hair loss
  • Rashes
  • Tiredness
  • Nausea, vomiting and diarrhea
  • Constipation
  • High blood sugar levels
  • Dizziness, impaired sensation, tingling sensation, abnormal taste
  • Vision and Hearing problem
  • Frequent urination
  • Muscle damage, pain in muscles and joints
  • Weight changes
  • Infections and wounds
  • Amnesia
  • Abnormal blood cell counts
  • Loss of appetite
  • Sleep problems
  • Memory loss
  • Difficulty concentrating, changes in mental status and alertness
  • Coordination problems

Safety Advice for TEMOREL 5 CAPSULE 5'SArrow

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Pregnancy

UNSAFE

TEMOREL 5 CAPSULE 5'S is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.

Dosage of TEMOREL 5 CAPSULE 5'SArrow

  • Always take TEMOREL 5 CAPSULE 5'S exactly as your doctor tells you to. The dosage will be determined by your physician, taking into account your individual needs, height, and weight. It's crucial to adhere to their specific instructions for the best possible outcome.
  • For optimal absorption and effectiveness, swallow the TEMOREL 5 CAPSULE 5'S capsule whole with a full glass of water on an empty stomach. This typically means taking it at least 30 minutes before a meal or two hours after eating.
  • Do not, under any circumstances, attempt to open, crush, or chew the capsule. The medication is designed for controlled release, and altering the capsule's form can disrupt this mechanism, leading to potential side effects or reduced efficacy. Furthermore, avoid direct contact of the contents of open capsules with your skin, as it may cause irritation.
  • If you have any questions or concerns regarding the dosage or administration of TEMOREL 5 CAPSULE 5'S, don't hesitate to consult your doctor or pharmacist. They can provide personalized guidance and address any specific issues you may encounter.

How to store TEMOREL 5 CAPSULE 5'S?Arrow

  • Keep TEMOREL 5MG CAP 1X5 away from the reach of children and pets.
  • Store TEMOREL 5MG CAP 1X5 in a refrigerator (2 - 8°C). Do not freeze.

Benefits of TEMOREL 5 CAPSULE 5'SArrow

  • TEMOREL 5 CAPSULE 5'S works by directly targeting the DNA and RNA production within cancer cells. Cancer cells rapidly divide and multiply, which requires them to create new DNA and RNA at a fast rate. TEMOREL 5 CAPSULE 5'S interferes with this process by inhibiting the creation of these essential genetic materials. This action disrupts the cancer cells' ability to replicate, effectively slowing down or stopping their growth and spread throughout the body.
  • By disrupting the DNA and RNA synthesis, TEMOREL 5 CAPSULE 5'S can induce apoptosis, or programmed cell death, in cancer cells. This mechanism is crucial in preventing the further proliferation of cancerous cells and reducing the tumor size. The targeted approach of TEMOREL 5 CAPSULE 5'S minimizes damage to healthy cells, leading to fewer side effects compared to traditional chemotherapy.
  • The inhibition of cancer cell growth and multiplication is a key factor in preventing metastasis, which is the spread of cancer to other parts of the body. TEMOREL 5 CAPSULE 5'S helps to control the spread by limiting the ability of cancerous cells to form new tumors in distant organs. This contributes to improved patient outcomes and a better quality of life during cancer treatment.

How to use TEMOREL 5 CAPSULE 5'SArrow

  • Always take TEMOREL 5 CAPSULE 5'S exactly as your doctor directs. The dosage will be determined by your doctor, considering your individual height and weight to ensure optimal effectiveness and minimize potential side effects. It is crucial to adhere to these personalized instructions for the best possible outcome.
  • Swallow the TEMOREL 5 CAPSULE 5'S whole with a full glass of water. For best absorption and to maximize the medication's effectiveness, take it on an empty stomach, ideally 30 minutes to an hour before a meal. This ensures that the medication is absorbed properly and works as intended.
  • Do not open, crush, or chew the capsule. The medication is designed for controlled release, and altering the capsule's form can affect how the drug is absorbed and utilized by your body. Avoid direct contact of the open capsule with your skin, as the contents may cause irritation. If contact occurs, wash the area thoroughly with soap and water.
  • If you have any concerns or questions regarding how to take TEMOREL 5 CAPSULE 5'S, consult with your physician or pharmacist. They can provide additional clarification and address any specific circumstances you may have. Do not exceed the prescribed dosage without consulting your doctor.
  • Consistent adherence to the prescribed dosage and instructions is essential for the successful management of your condition. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

FAQs

What class of medication is TEMOREL 5 CAPSULE 5'S?Arrow

TEMOREL 5 CAPSULE 5'S belongs to the class of medications called Antitumor agents

Can children use TEMOREL 5 CAPSULE 5'S?Arrow

No, TEMOREL 5 CAPSULE 5'S is not recommended for usage in children under 3. There is limited information on patients over the age of 3 who have taken this medication. Consult your doctor before taking TEMOREL 5 CAPSULE 5'S.

What is the best time to take TEMOREL 5 CAPSULE 5'S?Arrow

It is best to take TEMOREL 5 CAPSULE 5'S once a day on an empty stomach. Take the capsule at the same time every day for better results.

Can I take vaccinations while taking TEMOREL 5 CAPSULE 5'S?Arrow

No, The live vaccine may interact with TEMOREL 5 CAPSULE 5'S. Hence, without consulting your healthcare provider, this medication should not be taken with any vaccinations.

Can I drive while taking TEMOREL 5 CAPSULE 5'S?Arrow

No, taking TEMOREL 5 CAPSULE 5'S while driving and operating heavy machines may cause dizziness, sleepiness, and decreased alertness, affecting your vision.

Does TEMOREL 5 CAPSULE 5'S interact with other drugs?Arrow

There are no known interactions of TEMOREL 5 CAPSULE 5'S with other drugs.

What advice should I follow while taking TEMOREL 5 CAPSULE 5'S?Arrow

It is advised to use effective birth control for both men and women taking TEMOREL 5 CAPSULE 5'S. Women of reproductive potential must use effective contraception during and after six months of therapy. Male patients receiving TEMOREL 5 CAPSULE 5'S treatment should refrain from fathering children and should use reliable contraception during and for three months following the treatment. Your doctor could suggest routine blood tests to check your electrolyte levels, blood cell count, and liver function.

What is Temozolomide?Arrow

TEMOZOLOMIDE is molecule/combination used for making TEMOREL 5 CAPSULE 5'S.

For which ailments/diseases/conditions TEMOREL 5 CAPSULE 5'S is prescribed?Arrow

TEMOREL 5 CAPSULE 5'S is prescribed for Oncology related ailments/diseases/conditions.

References

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Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC)

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Pfizer, US Food and Drug Administration

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Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist

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Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol.

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Good for generic medicine, quality medicine with affordable rate

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Reviewed on 03-02-2024

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Marketer / Manufacturer Details

RELIANCE LIFE SCIENCES

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India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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