TEPASTIM 15 INJECTION
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TEPASTIM 15 INJECTION
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TEPASTIM 15 INJECTION

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TEPASTIM 15 INJECTION

By ZYDUS LIFESCIENCES LIMITED

MRP

₹

10870.31

₹8696.25

20 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About TEPASTIM 15 INJECTION

  • TEPASTIM 15 INJECTION is an antineoplastic medication containing the active ingredient Thiotepa. It is often used in conjunction with other anti-cancer drugs as part of a treatment plan prior to stem cell transplantation, particularly for adult patients whose cancer has affected the lymph nodes of the central nervous system. This medication plays a vital role in preparing the body for stem cell transplants, reducing the likelihood of graft rejection, where the body's immune system attacks the transplanted cells. Additionally, TEPASTIM 15 INJECTION is effective in managing fluid buildup within body cavities caused by cancerous conditions affecting serous membranes.
  • Beyond its use in stem cell transplant preparation and managing serous effusions, TEPASTIM 15 INJECTION is also indicated for the treatment of various cancers, including breast cancer, ovarian cancer, and bladder cancer. Its mechanism of action involves targeting and disrupting the growth of cancer cells.
  • Patients undergoing treatment with TEPASTIM 15 INJECTION may experience side effects such as diarrhea, skin rashes, bleeding, the presence of blood in the urine, and cytomegalovirus (CMV) infection. It is crucial to promptly inform your doctor if any of these side effects occur and if they become bothersome or persist. Your healthcare provider can offer guidance on managing these side effects and determine if any adjustments to your treatment plan are necessary.
  • Before starting TEPASTIM 15 INJECTION, disclose any allergies you have, particularly if you are hypersensitive to Thiotepa or any other ingredients in the injection. This medication is contraindicated in individuals receiving live virus or bacterial vaccines, including the yellow fever vaccine. Exercise caution and inform your doctor if you have a history of heart, liver, kidney, or lung disease, or if you have a condition called profound myelosuppression, which involves a decrease in blood cell production (anemia, neutropenia, and thrombocytopenia). Regular monitoring of liver and heart function is essential during treatment. TEPASTIM 15 INJECTION is generally not recommended for use during pregnancy and breastfeeding.

Uses of TEPASTIM 15 INJECTION

  • Preparing pediatric patients with class 3 beta-thalassemia for allogeneic hematopoietic stem cell transplantation. This process involves readying the patient for transplant, which may include chemotherapy or radiation therapy.
  • Treating adenocarcinoma of the breast and ovary. This encompasses various therapeutic approaches to manage cancers arising in these organs, such as surgery, chemotherapy, radiation therapy, and targeted therapies.
  • Treating superficial papillary cancer of the urinary bladder. Approaches used to manage this type of cancer include transurethral resection, intravesical chemotherapy, and BCG therapy.

Side Effects of TEPASTIM 15 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

  • Severe drop in blood cell count
  • Heart problem
  • Kidney damage
  • Nerve damage
  • Lung toxicity
  • Liver toxicity
  • Cytomegalovirus infection
  • Hemorrhage
  • Diarrhea
  • Blood in urine
  • Rashes

Safety Advice for TEPASTIM 15 INJECTIONArrow

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Pregnancy

UNSAFE

TEPASTIM 15 INJECTION is unsafe to use during pregnancy as it may cause fetal harm. Hence, Consult your doctor for advice.

Dosage of TEPASTIM 15 INJECTIONArrow

  • TEPASTIM 15 INJECTION administration necessitates the expertise of a qualified physician, well-versed in the intricacies of high-dose chemotherapy regimens and stem cell transplantation procedures. This medication should only be administered under the direct supervision and guidance of such a healthcare professional.
  • The physician's experience is crucial to ensure the safe and effective delivery of TEPASTIM 15 INJECTION, as well as to manage any potential complications that may arise during or after the treatment. Their knowledge enables accurate dosage calculation based on individual patient needs and monitoring for adverse reactions.
  • Furthermore, a physician experienced in high-dose chemotherapy and stem cell transplant is best equipped to handle the unique challenges presented by these intensive treatments. This includes managing potential side effects like neutropenic fever, infections, and graft-versus-host disease, which require prompt and skilled intervention to minimize patient risk.
  • Therefore, adhering to this guideline is of paramount importance to guarantee patient safety and optimize the therapeutic benefits of TEPASTIM 15 INJECTION within the context of high-dose chemotherapy and stem cell transplantation.

How to store TEPASTIM 15 INJECTION?Arrow

  • Keep TEPASTIM 15MG INJ away from the reach of children and pets.
  • Store TEPASTIM 15MG INJ in a refrigerator (2 - 8°C). Do not freeze.

Benefits of TEPASTIM 15 INJECTIONArrow

  • TEPASTIM 15 INJECTION is designed to combat cancer cells by directly interfering with their genetic material, specifically DNA and RNA. This mechanism of action is crucial in disrupting the uncontrolled growth and multiplication characteristic of cancer. By directly targeting DNA, the injection induces breaks in the DNA strands, a critical step in preventing the cancer cells from replicating effectively.
  • The cross-linking process, facilitated by TEPASTIM 15 INJECTION, plays a pivotal role in the drug's toxicity towards cancer cells. This process leads to a cascade of events culminating in a cytotoxic effect, ultimately causing the death of tumor cells. This targeted approach minimizes damage to healthy cells, focusing primarily on eradicating the cancerous tissue.
  • In essence, TEPASTIM 15 INJECTION works at the molecular level to destabilize cancer cells' ability to proliferate, leading to their destruction and contributing to the overall goal of managing and combating the progression of cancer.

How to use TEPASTIM 15 INJECTIONArrow

  • TEPASTIM 15 INJECTION is a potent medication and should only be administered under the direct supervision of a qualified physician.
  • This physician should possess extensive experience in managing patients undergoing high-dose chemotherapy regimens and stem cell transplantation procedures. This is to ensure patient safety and optimize treatment outcomes.
  • The administration of TEPASTIM 15 INJECTION requires careful monitoring and specialized knowledge to manage potential complications associated with its use in such intensive treatment settings.
  • It's crucial that the healthcare provider is well-versed in the appropriate dosage, administration techniques, and supportive care measures necessary for patients undergoing these complex therapies.

FAQs

Can pregnant women use TEPASTIM 15 INJECTION?Arrow

No, It is unsafe to use TEPASTIM 15 INJECTION during pregnancy as it may cause harm to the developing fetus. Consult your doctor before taking this medicine.

Which is the best area to inject TEPASTIM 15 INJECTION?Arrow

TEPASTIM 15 INJECTION is administered intravenously (into a vein) by a doctor or nurse in a medical facility.

Can I drive after taking TEPASTIM 15 INJECTION?Arrow

TEPASTIM 15 INJECTION can cause convulsion, hallucination, delirium, dizziness, headache and blurred vision. Avoid driving or operating any machine if you experience any of these side effects.

What class of medication is TEPASTIM 15 INJECTION?Arrow

TEPASTIM 15 INJECTION belongs to the class of medications known as alkylating agents or antineoplastics.

Can I take vaccinations while taking TEPASTIM 15 INJECTION?Arrow

No, The live vaccine may interact with TEPASTIM 15 INJECTION. Hence, without consulting your healthcare provider, this medication should not be taken with any vaccinations.

Is there any known drug interaction with TEPASTIM 15 INJECTION?Arrow

There is NULL interaction of TEPASTIM 15 INJECTION with other drugs

What precautions should I take while using TEPASTIM 15 INJECTION?Arrow

It is advised to avoid ingestion, inhalation, or skin and eye contact. Skin reactions may occur with accidental exposure. Using gloves and protective clothing to prevent accidental skin contact is recommended. If the TEPASTIM 15 INJECTION solution contacts the skin or mucosa, immediately wash the skin thoroughly with soap and water or rinse the mucosa with water and seek medical attention.

Which molecule/combination is used for making TEPASTIM 15 INJECTION?Arrow

THIOTEPA is molecule/combination used for making TEPASTIM 15 INJECTION.

For what type of ailments/diseases/conditions TEPASTIM 15 INJECTION is prescribed?Arrow

TEPASTIM 15 INJECTION is prescribed for ailments/diseases/conditions in Oncology.

References

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ADIENNE SA

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Pfizer, US Food and Drug Administration

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Ratings & Review

Best service ever.. I used to come down all the way from kerla to get medicines frm here

Mint Raj

•

Reviewed on 15-05-2023

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(5/5)

So good it's give information with medicine

sunil Nayi

•

Reviewed on 21-04-2024

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(5/5)

Good discounts available for all medicine.

Akash Patel

•

Reviewed on 01-12-2023

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(4/5)

Medicines available at good discounted rates and it really help the pockets of the customer...even they help in getting medicines when you order and give your number ..

Pashupati Nath Pandey

•

Reviewed on 03-02-2024

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(5/5)

Discount on medicine is good But OTC discount is zero and very low

Abhishek Solanki

•

Reviewed on 05-12-2022

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(3/5)


Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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