THYMOGAM 250MG/5ML INJECTION
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THYMOGAM 250MG/5ML INJECTION
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THYMOGAM 250MG/5ML INJECTION

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THYMOGAM 250MG/5ML INJECTION

By BHARAT SERUMS & VACCINES LIMITED

MRP

15276.25

₹10700

29.96 % OFF

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Product Details
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About THYMOGAM 250MG/5ML INJECTION

  • THYMOGAM 250MG/5ML INJECTION contains Antithymocyte Immunoglobulins as its main ingredient. This is a pure, sterile form of immune proteins (gamma globulin), taken from horses that have been given human white blood cell components to make them produce antibodies. This medicine is used after procedures like kidney transplantation and other similar treatments. It helps manage and prevent the body from rejecting the new organ. When you receive a transplanted organ, your body's defense system (immune system) sees the new organ's cells as foreign invaders. This causes a strong reaction that can damage or destroy the new organ. THYMOGAM 250MG/5ML INJECTION works by calming down this aggressive immune response, making it less likely for your body to reject the transplant.
  • The injection is also used to treat severe aplastic anemia. This is a serious condition where your bone marrow doesn't make enough blood cells. In some cases, aplastic anemia happens because your immune system is attacking your bone marrow. THYMOGAM 250MG/5ML INJECTION helps by suppressing this overactive immune system response, reducing the attack on the bone marrow cells. This can help your bone marrow start producing healthy blood cells again. Using this injection can sometimes mean you need lower doses or shorter courses of other strong medicines like corticosteroids, which helps reduce their side effects and risks.
  • It's important to note that THYMOGAM 250MG/5ML INJECTION is a powerful medicine that significantly affects the immune system. Because your immune system is suppressed, you are more vulnerable to infections. Your doctor will monitor you closely for any signs of infection during and after treatment. Blood tests will be done regularly to check your blood cell counts and how you are responding. You should not receive this injection if you have ever had a severe allergic reaction to THYMOGAM 250MG/5ML INJECTION or similar products, or any of its ingredients. It is generally recommended to avoid live vaccines while being treated with this medicine because your immune system may not be able to respond properly. If you have an active infection, especially a severe one, treatment with THYMOGAM 250MG/5ML INJECTION should usually be delayed until the infection is treated and resolved. Your healthcare provider will determine if this medicine is right for you based on your specific condition and medical history.

Uses of THYMOGAM 250MG/5ML INJECTION

  • To prevent the body's immune system from attacking and rejecting a transplanted organ.
  • Treatment for Aplastic Anemia, a serious condition where the body doesn't produce enough blood cells.
  • Used to manage or treat the body's rejection of a transplanted kidney (known medically as Renal Allograft Rejection).
  • For Autoimmune Hemolytic Anemia, a type of blood disorder where the body's immune system attacks its own red blood cells.
  • For Myasthenia Gravis, a condition that causes weakness in the muscles used for movement.

Side Effects of THYMOGAM 250MG/5ML INJECTION
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THYMOGAM 250MG/5ML INJECTION may cause side effects. These are unwanted symptoms that can occur with any medicine, although not everyone who takes it will experience them.

Safety Advice for THYMOGAM 250MG/5ML INJECTION
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Pregnancy

Consult a Doctor

If you are taking THYMOGAM 250MG/5ML INJECTION and are planning to become pregnant or are already pregnant, it is important to discuss this with your healthcare professional.

Dosage of THYMOGAM 250MG/5ML INJECTION
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  • THYMOGAM 250MG/5ML INJECTION is typically administered into a vein (intravenously). This is always done in a hospital or clinical setting under the close supervision of a trained healthcare professional. You will not self-administer this medication. The exact amount of THYMOGAM 250MG/5ML INJECTION you receive and how quickly it is given (the infusion rate) will be carefully determined by your doctor or nurse. Several factors influence this decision, including the specific medical condition being treated, your body weight, and how your body is responding to the treatment. Administering this medication requires precise calculation and monitoring to ensure safety and effectiveness, which is why it must be given in a controlled medical environment. Your healthcare team will monitor you throughout the infusion process to manage any potential reactions and ensure you receive the optimal dose for your condition.

How to store THYMOGAM 250MG/5ML INJECTION?
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  • Keep THYMOGAM 250MG INJ 5ML away from the reach of children and pets.
  • Store THYMOGAM 250MG INJ 5ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of THYMOGAM 250MG/5ML INJECTION
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  • The main benefit of THYMOGAM 250MG/5ML INJECTION is its ability to significantly calm down the body's immune response. It works by targeting and reducing the number of T lymphocytes, which are key cells involved in attacking foreign substances or even the body's own tissues in certain conditions. This suppression is crucial in preventing the rejection of transplanted organs, dramatically increasing the likelihood of a successful transplant and helping the new organ survive longer. Beyond transplantation, THYMOGAM 250MG/5ML INJECTION is also a vital treatment for severe conditions like aplastic anemia, where the immune system mistakenly attacks the bone marrow, and graft-versus-host disease (GVHD), a complication after bone marrow transplants where the donor cells attack the recipient's body. By modulating the immune response, this injection helps reduce this harmful attack, ease severe symptoms, and promote the recovery of normal cell production or acceptance of the transplanted tissue, offering significant relief and improved outcomes for patients.

How to use THYMOGAM 250MG/5ML INJECTION
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  • THYMOGAM 250MG/5ML INJECTION is given as an intravenous infusion. This means it is delivered directly into your vein using a drip. You will always receive this injection in a hospital or a clinical setting under the supervision of trained medical professionals. It is never meant for self-administration at home. The exact amount of THYMOGAM 250MG/5ML INJECTION you receive, and how quickly it is given, will be carefully decided by your doctor or healthcare team. They will consider several important factors, including the specific medical condition being treated, your individual body weight, and how well your body is responding to the therapy. This personalized approach ensures that you receive the safest and most effective dose for your needs. Be sure to discuss any concerns you have about the administration with your healthcare provider.

FAQs

How can I minimize the risk of infections while on THYMOGAM 250MG/5ML INJECTION therapy?

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It is important to follow proper hygiene practices to reduce the risk of infections, such as frequent handwashing and avoiding close contact with contagious individuals. Inform your healthcare provider about any signs of infection, such as fever, cough, or sore throat, for prompt evaluation and appropriate treatment.

Can THYMOGAM 250MG/5ML INJECTION cause long-term kidney or liver damage?

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While THYMOGAM 250MG/5ML INJECTION can potentially cause kidney or liver dysfunction, the risk of long-term damage is generally low. However, regular monitoring of kidney and liver function is important during the treatment to detect any early signs of impairment. Report any significant changes in urinary output or jaundice (yellowing of the skin or eyes) to your healthcare provider.

What steps can be taken to minimize infusion-related reactions?

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Infusion-related reactions, such as fever and chills, can occur during THYMOGAM 250MG/5ML INJECTION administration. Slowing down the infusion rate, pre-medicating with antihistamines or corticosteroids, or using other supportive measures as your healthcare provider recommends can help minimize these reactions.

Is there an increased risk of developing malignancies with long-term THYMOGAM 250MG/5ML INJECTION use?

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Prolonged use of immunosuppressive agents, including THYMOGAM 250MG/5ML INJECTION, may be associated with a slightly increased risk of developing certain malignancies. However, the overall risk is generally low. As your healthcare provider recommends, regular monitoring and screening for malignancies can help detect any potential issues early.

Can THYMOGAM 250MG/5ML INJECTION increase the risk of viral infections other than cytomegalovirus (CMV)?

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While CMV reactivation is a known risk with THYMOGAM 250MG/5ML INJECTION therapy, there may also be an increased susceptibility to other viral infections. It is important to discuss any specific concerns or symptoms with your healthcare provider, who can evaluate the risk and provide appropriate guidance.

Are any specific tests or monitoring required for THYMOGAM 250MG/5ML INJECTION therapy patients?

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Monitoring kidney function, liver function, blood counts, and viral markers may be necessary during THYMOGAM 250MG/5ML INJECTION treatment. Your healthcare provider will determine the appropriate monitoring schedule based on your condition and treatment plan.

Does THYMOGAM 250MG/5ML INJECTION interact with other medications?

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Always consult with a qualified healthcare professional regarding the use of THYMOGAM 250MG/5ML INJECTION or any other medication to understand potential interactions.

What general advice or precautions should I follow while using THYMOGAM 250MG/5ML INJECTION?

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It is essential to follow proper hygiene and infection surveillance due to the increased infection risk. Regular monitoring of liver function, kidney function, and blood counts is advised. Be aware of potential infusion-related reactions. Special consideration is needed for pregnant, breastfeeding, pediatric, and geriatric patients. Discuss any psychological effects with your doctor. Close consultation with healthcare professionals is key for safe use.

What is the main component of THYMOGAM 250MG/5ML INJECTION?

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THYMOGAM 250MG/5ML INJECTION is made using ANTITHYMOCYTE IMMUNOGLOBULINS.

What conditions is THYMOGAM 250MG/5ML INJECTION prescribed for?

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THYMOGAM 250MG/5ML INJECTION is typically prescribed for conditions related to Transplant.

How is THYMOGAM 250MG/5ML INJECTION used in Transplant?

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THYMOGAM 250MG/5ML INJECTION is used in Transplant procedures, usually to prevent or treat rejection of the transplanted organ.

References

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Genzyme Corporation, US Food and Drug Administration,

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Reviewed on 07-11-2022

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Marketer / Manufacturer Details

BHARAT SERUMS & VACCINES LIMITED

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India

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MRP

15276.25

₹10700

29.96 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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