TISKATEL M 50MG TABLET 10'S

How TISKATEL M 50MG TABLET 10'S Works

• TISKATEL M 50MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines two active ingredients: sitagliptin and metformin. Each component works through different mechanisms to lower blood sugar levels.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the amount of incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released by the intestine throughout the day and especially after meals. These hormones play a crucial role in regulating blood sugar levels. Sitagliptin inhibits the DPP-4 enzyme, which normally breaks down these incretin hormones. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. The increased incretin levels enhance insulin release from the pancreas when blood sugar is high (after meals) and decrease the amount of glucagon secreted by the pancreas when blood sugar is high. Glucagon is a hormone that raises blood sugar levels by stimulating the liver to release stored glucose. Therefore, sitagliptin helps to lower blood sugar levels by increasing insulin secretion and decreasing glucagon secretion in a glucose-dependent manner, meaning it primarily works when blood sugar is elevated.
• Metformin, on the other hand, is a biguanide and works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces the amount of glucose the liver releases into the bloodstream and helps muscle cells use insulin more effectively. Metformin does not stimulate insulin release, so it does not typically cause hypoglycemia (low blood sugar) when used alone. Specifically, metformin works through several mechanisms: it reduces hepatic glucose production by inhibiting gluconeogenesis (the production of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). It also enhances insulin sensitivity in peripheral tissues, such as muscle, allowing these tissues to take up and use glucose more efficiently. Additionally, metformin slows down the absorption of glucose from the intestines into the bloodstream.
• By combining sitagliptin and metformin, TISKATEL M 50MG TABLET 10'S addresses multiple aspects of type 2 diabetes. Sitagliptin enhances the effects of incretin hormones to improve insulin secretion and reduce glucagon secretion, while metformin reduces glucose production in the liver and improves insulin sensitivity. This dual action helps to achieve better blood sugar control than either medication could achieve alone. This synergistic effect allows for better management of blood glucose levels throughout the day, particularly after meals. It is important to take TISKATEL M 50MG TABLET 10'S as directed by your healthcare provider, usually with meals, to maximize its effectiveness and minimize potential side effects. Regular monitoring of blood sugar levels is also essential to ensure the medication is working properly and to adjust the dosage if needed.

Common side effects of TISKATEL M 50MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, fatigue, headache, dizziness, and skin rash. Less common but potentially serious side effects include liver problems (such as jaundice, dark urine, persistent fatigue), allergic reactions (such as hives, swelling of the face, lips, or tongue, difficulty breathing), and changes in blood sugar levels. Other possible side effects are muscle pain, joint pain, and depression. Consult your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of TISKATEL M 50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep TISKATEL M 50MG TAB 1X10 away from the reach of children and pets.
• Store TISKATEL M 50MG TAB 1X10 at room temperature.

• Take TISKATEL M 50MG TABLET 10'S as prescribed by your doctor. It's usually taken once or twice daily, with or without food, but consistency is key. Try to take it at the same time(s) each day to maintain a steady level of medication in your system and optimize its effectiveness in controlling your blood sugar. Don't alter the dosage without consulting your physician.
• TISKATEL M 50MG TABLET 10'S helps manage blood sugar levels in people with type 2 diabetes. It works by improving your body's response to insulin and decreasing glucose production in the liver. Remember, this medication is most effective when combined with a healthy diet and regular exercise. It is not a substitute for lifestyle changes but rather a supportive treatment.
• Be aware of potential side effects. Common side effects include nausea, diarrhea, stomach upset, and headache. If these persist or worsen, inform your doctor. Rarely, it can cause a serious side effect called lactic acidosis. Seek immediate medical attention if you experience symptoms like muscle pain or weakness, trouble breathing, stomach pain with nausea, vomiting, or dizziness.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting TISKATEL M 50MG TABLET 10'S. Certain medications can interact with this medicine, affecting how it works or increasing the risk of side effects. This includes over-the-counter drugs as well.
• Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. This will help you track how well the medication is working and allow your doctor to make adjustments to your treatment plan if needed. Keep a record of your blood sugar readings to share with your healthcare provider during appointments. Adhere to the diet and exercise plan suggested by your physician.
• If you are scheduled for any surgery or medical procedure, inform your doctor that you are taking TISKATEL M 50MG TABLET 10'S. It may be necessary to temporarily discontinue the medication before the procedure, especially if it involves contrast dyes or anesthesia.
• Store TISKATEL M 50MG TABLET 10'S at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has expired. Dispose of it properly according to local regulations.

• TISKATEL M 50MG TABLET 10'S can be taken with or without food, but it's recommended to take it at a fixed time to maintain consistent blood levels. While food doesn't significantly alter the medicine's effectiveness, avoid excessive alcohol consumption as it can increase the risk of low blood sugar (hypoglycemia) and other side effects. Consult your doctor for specific dietary advice while taking this medication.