TONACT PLUS TABLET 10'S

How TONACT PLUS TABLET 10'S Works

• TONACT PLUS TABLET 10'S is a combination medication designed to address dyslipidemia, a condition characterized by abnormal levels of lipids (fats) in the blood. It combines two active ingredients: Atorvastatin and Ezetimibe, each working through different mechanisms to lower cholesterol and improve lipid profiles.
• Atorvastatin belongs to a class of drugs called statins, or HMG-CoA reductase inhibitors. It primarily works by blocking the action of HMG-CoA reductase, an enzyme crucial in the liver's production of cholesterol. By inhibiting this enzyme, Atorvastatin reduces the amount of cholesterol the liver produces. This leads to a decrease in LDL-cholesterol (low-density lipoprotein), often referred to as 'bad' cholesterol, which is a major contributor to plaque buildup in arteries. Statins also have the added benefit of modestly increasing HDL-cholesterol (high-density lipoprotein), or 'good' cholesterol, which helps remove cholesterol from the arteries.
• Ezetimibe functions differently than Atorvastatin. It works by inhibiting the absorption of cholesterol in the small intestine. Cholesterol comes from two sources: the diet and the liver. Ezetimibe selectively blocks the absorption of cholesterol from dietary sources and also reduces the reabsorption of cholesterol excreted in the bile. This action complements the cholesterol-lowering effects of Atorvastatin, which primarily targets cholesterol production in the liver. By reducing cholesterol absorption, Ezetimibe further lowers LDL-cholesterol levels in the bloodstream.
• The combined action of Atorvastatin and Ezetimibe in TONACT PLUS TABLET 10'S provides a dual approach to managing cholesterol levels. By reducing both cholesterol production and absorption, this medication can more effectively lower LDL-cholesterol than either drug alone. This synergistic effect helps to reduce the risk of cardiovascular events such as heart attack and stroke. Additionally, the medication helps in overall improvement of lipid profile by decreasing triglycerides and increasing HDL cholesterol
• In summary, TONACT PLUS TABLET 10'S works by utilizing Atorvastatin to reduce cholesterol production in the liver and Ezetimibe to inhibit cholesterol absorption in the small intestine. This combination therapy effectively lowers LDL-cholesterol, triglycerides and increases HDL-cholesterol, thus reducing the risk of cardiovascular diseases.

Common side effects of Tonact Plus Tablet may include: Headache, Muscle pain, Weakness, Tiredness, Nausea, Vomiting, Diarrhea, Indigestion, Abdominal pain, Constipation, Increased liver enzymes, Dizziness, Sleep disturbances (insomnia), Cold symptoms (stuffy nose, sneezing, sore throat). Uncommon side effects may include: Allergic reactions (rash, itching, swelling), Muscle cramps, Joint pain, Memory loss, Confusion, Peripheral neuropathy (numbness or tingling in hands and feet), Pancreatitis, Hepatitis, Jaundice, Thrombocytopenia (low platelet count). Rare side effects may include: Myopathy (muscle disease), Rhabdomyolysis (muscle breakdown), Liver failure. Other possible side effects: Erectile dysfunction, Depression, Breathing problems.

• If you miss a dose of TONACT PLUS TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep TONACT PLUS TAB 1X10 away from the reach of children and pets.
• Store TONACT PLUS TAB 1X10 at room temperature.

• **Take Tonact Plus as Prescribed:** Always follow your doctor's instructions regarding dosage and timing. Consistency is key to managing your cholesterol levels effectively.
• **Maintain a Healthy Lifestyle:** Tonact Plus works best when combined with a heart-healthy diet, regular exercise, and weight management. Limit saturated and trans fats, and increase your intake of fruits, vegetables, and whole grains. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
• **Be Aware of Potential Side Effects:** While generally well-tolerated, Tonact Plus can cause side effects like muscle pain or weakness (myalgia). Report any unusual symptoms to your doctor promptly. Other possible side effects include digestive issues and liver problems. Regular monitoring of liver function may be recommended.
• **Inform Your Doctor About Other Medications:** Drug interactions can affect how Tonact Plus works. Make sure your doctor is aware of all medications, supplements, and herbal remedies you are taking, including over-the-counter drugs.
• **Monitor Your Cholesterol Levels Regularly:** Regular blood tests are essential to track your progress and ensure that Tonact Plus is effectively lowering your cholesterol. Work closely with your doctor to adjust your treatment plan as needed and achieve your target cholesterol levels. Also, avoid alcohol consumption while on medication.
• **Understand the Purpose of Tonact Plus:** Tonact Plus is a combination medication used to lower bad cholesterol (LDL) and raise good cholesterol (HDL), reducing the risk of heart disease and stroke. Knowing why you're taking it can help you stay motivated and adherent to your treatment plan.

• TONACT PLUS TABLET 10'S can be taken with or without food. However, it is important to maintain a consistent dietary pattern. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it can increase the levels of atorvastatin in your blood, potentially leading to side effects. Discuss any dietary concerns or restrictions with your doctor or pharmacist.