TOPAZ 50MG TABLET 15'S uses, side effects & dosage information
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TOPAZ 50MG TABLET 15'S uses, side effects & dosage information
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TOPAZ 50MG TABLET 15'S

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TOPAZ 50MG TABLET 15'S

By INTAS PHARMACEUTICALS LIMITED

MRP

223.75

₹190.19

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About TOPAZ 50MG TABLET 15'S

  • TOPAZ 50MG TABLET 15'S is a medication prescribed for the management of epilepsy (seizures) and the prevention of migraine headaches. It is also indicated for the treatment of Lennox-Gastaut syndrome, a rare and severe form of epilepsy that typically begins in early childhood. This medication works by stabilizing electrical activity in the brain, reducing the likelihood of seizures and migraines.
  • TOPAZ 50MG TABLET 15'S can be administered with or without food. However, it is recommended to take it at the same time each day to maintain consistent blood levels of the medication. If you miss a dose, take it as soon as you remember. It is crucial to complete the full course of treatment, even if you start feeling better. Abruptly stopping this medication without consulting your doctor can lead to an increased frequency of seizures. Your healthcare provider may recommend regular monitoring of serum bicarbonate levels while you are taking this medicine to ensure safety and efficacy.
  • Common side effects associated with TOPAZ 50MG TABLET 15'S include nausea, altered taste perception, fatigue, diarrhea, weight loss, decreased appetite, and memory impairment. Some individuals may also experience vision problems such as myopia (nearsightedness) or glaucoma. Therefore, it is advisable to have your eyesight checked before commencing treatment and periodically thereafter. Dizziness and sleepiness are also potential side effects; avoid driving or operating heavy machinery until you understand how this medication affects you. If these side effects become bothersome or persist, please consult your doctor for guidance.
  • It's important to note that while TOPAZ 50MG TABLET 15'S is effective for many, individual responses may vary. Discuss any concerns or existing medical conditions with your doctor before starting this medication. They can provide personalized advice and adjust the dosage as needed to optimize treatment outcomes.

Uses of TOPAZ 50MG TABLET 15'S

  • Prevention of Migraine. Measures to reduce the occurrence, severity, and frequency of migraines.
  • Epilepsy/Seizures. Management of seizures caused by abnormal electrical activity in the brain.
  • Lennox–Gastaut syndrome. A severe form of epilepsy that begins in childhood and is difficult to treat.

How TOPAZ 50MG TABLET 15'S Works

  • TOPAZ 50MG TABLET 15'S is classified as an antiepileptic medication, playing a crucial role in managing and controlling seizures, also known as fits. Seizures arise from abnormal and excessive electrical activity within the nerve cells of the brain. TOPAZ 50MG TABLET 15'S functions by stabilizing these nerve cells, effectively reducing the intensity and frequency of such erratic electrical discharges. This mechanism helps to restore a more balanced and controlled neural environment, preventing the onset of seizures.
  • By modulating the activity of nerve cells, TOPAZ 50MG TABLET 15'S ensures that the brain's electrical impulses remain within a normal range. This control is vital for individuals prone to epilepsy or other seizure disorders. The medication acts as a regulator, preventing the nerve cells from becoming overexcited and triggering a seizure. Consistent use of TOPAZ 50MG TABLET 15'S, as prescribed by a healthcare professional, helps maintain this equilibrium and significantly improves the quality of life for patients by reducing the likelihood of seizure episodes.
  • TOPAZ 50MG TABLET 15'S essentially works to calm the overactive nerve cells in the brain, making them less likely to fire abnormally. This results in a more stable neurological state, reducing the occurrence of seizures and fits. It is important to take TOPAZ 50MG TABLET 15'S exactly as directed by your doctor to achieve the best possible control over your condition.

Side Effects of TOPAZ 50MG TABLET 15'S
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Most side effects are temporary and resolve as your body adapts to the medication. However, if these side effects persist or cause you concern, please consult your doctor.

  • Abdominal pain
  • Diarrhea
  • Dizziness
  • Fatigue
  • Fever
  • Loss of appetite
  • Memory impairment
  • Nausea
  • Nervousness
  • Numbness
  • Psychomotor impairment
  • Sleepiness
  • Speech disorder
  • Taste change
  • Upper respiratory tract infection
  • Visual impairment
  • Weight loss

Safety Advice for TOPAZ 50MG TABLET 15'S
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Liver Function

Caution

TOPAZ 50MG TABLET 15'S should be used with caution in patients with liver disease. Dose adjustment of TOPAZ 50MG TABLET 15'S may be needed. Please consult your doctor.

Dosage of TOPAZ 50MG TABLET 15'S
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  • Dosage for Children: The initial dose for children (age 2 and above) with epilepsy is typically 0.5 to 1 mg per kg of body weight per day, which is increased gradually based on response and tolerability.
  • Dosage for Adults: The initial dose for adults with epilepsy or migraines is usually 25 to 50 mg per day, divided into two doses. The dose is then adjusted gradually, usually up to a maintenance dose of 100 to 200 mg per day.

How to store TOPAZ 50MG TABLET 15'S?
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  • Keep TOPAZ 50MG TAB 1X15 away from the reach of children and pets.
  • Store TOPAZ 50MG TAB 1X15 at room temperature.

Benefits of TOPAZ 50MG TABLET 15'S
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  • **Migraine Prevention:** It's not fully understood exactly how TOPAZ 50MG TABLET 15'S helps prevent migraines. It is believed to work by stabilizing the nerve cells in the brain, reducing abnormal and excessive activity that can trigger migraines. It might also increase activity in a specific area of the brain associated with migraine headaches. By reducing the frequency and severity of migraine attacks, TOPAZ 50MG TABLET 15'S can significantly improve your ability to participate in daily activities and enhance your overall quality of life.
  • **Epilepsy/Seizures:** TOPAZ 50MG TABLET 15'S is classified as an anticonvulsant, also known as an anti-epileptic medication. It functions by reducing the intensity of nerve impulses in the brain that lead to seizures. By controlling the occurrence of seizures, TOPAZ 50MG TABLET 15'S allows individuals to engage in their daily routines with greater confidence. This medication can alleviate symptoms such as confusion, involuntary jerking movements, temporary loss of awareness, as well as feelings of fear or anxiety associated with seizures.
  • TOPAZ 50MG TABLET 15'S does not cause physical or psychological dependence (addiction). It's important to adhere to the prescribed dosage and take it regularly for optimal effectiveness. Abruptly discontinuing the medication is not recommended, as it can potentially trigger seizures. Consistent adherence to the prescribed regimen is crucial for managing epilepsy effectively.
  • **Lennox–Gastaut Syndrome (LGS):** Lennox-Gastaut syndrome is a severe and rare form of epilepsy that generally manifests in early childhood. Children with LGS may experience various types of seizures. TOPAZ 50MG TABLET 15'S helps to prevent and control these seizures by decreasing the nerve impulses that cause them, offering relief and improved management of this challenging condition.

How to use TOPAZ 50MG TABLET 15'S
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  • Always follow your doctor's instructions regarding dosage and duration when taking this medication. It is crucial to adhere to their recommendations for optimal results and to minimize potential side effects.
  • Swallow the TOPAZ 50MG TABLET 15'S whole with a glass of water. Avoid chewing, crushing, or breaking the tablet, as this could affect how the medication is absorbed into your system and alter its effectiveness.
  • You can take TOPAZ 50MG TABLET 15'S with or without food. However, it's generally recommended to take it at the same time each day. This consistency helps maintain a steady level of the medicine in your body, maximizing its benefits. Establishing a routine, such as taking it with breakfast or before bed, can help you remember to take it regularly.
  • If you have any questions or concerns about how to take this medicine, don't hesitate to ask your doctor or pharmacist for clarification. They can provide personalized guidance based on your specific health condition and other medications you may be taking. Never adjust the dosage or stop taking the medicine without consulting your healthcare provider.

Quick Tips for TOPAZ 50MG TABLET 15'S
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  • Take TOPAZ 50MG TABLET 15'S regularly, exactly as your doctor prescribes. Adhering to a consistent schedule is crucial, as missing doses can increase the likelihood of seizures. Set a daily reminder if needed, and ensure you understand the dosage instructions thoroughly.
  • Once you start with a particular brand of your medication, try to stick with it unless otherwise directed by your healthcare provider. Switching brands can sometimes affect how the medication works in your body. Also, always check your supply to avoid running out, especially before travel or holidays.
  • Incorporate these healthy habits into your daily routine to potentially reduce the occurrence of seizures: Practice yoga regularly to reduce stress and promote relaxation. Aim for consistent, quality sleep each night. Reduce your screen time, including mobile phones and laptops, particularly before bed. Always take your medication at the scheduled times.
  • TOPAZ 50MG TABLET 15'S may cause drowsiness or dizziness as a side effect. Be cautious when performing activities that demand alertness, such as driving or operating machinery, until you're sure how the medication affects you. If dizziness occurs, sit or lie down until it passes.
  • Staying hydrated is important while taking TOPAZ 50MG TABLET 15'S. Drink plenty of water throughout the day to help prevent kidney stones, a potential side effect. Aim for at least eight glasses of water daily, and adjust based on your activity level and climate.
  • Keep an eye on your weight while on this medication, as TOPAZ 50MG TABLET 15'S can sometimes lead to weight gain in some individuals. Maintain a balanced diet and exercise regularly to help manage your weight effectively. Consult your doctor or a registered dietitian for personalized advice.
  • Pay close attention to your mental and emotional well-being while taking TOPAZ 50MG TABLET 15'S. If you experience any sudden or significant mood changes, feelings of depression, or suicidal thoughts, it's crucial to inform your doctor immediately. These symptoms require prompt medical attention.
  • It's very important not to abruptly stop taking TOPAZ 50MG TABLET 15'S without first discussing it with your doctor. Suddenly discontinuing the medication can lead to a rebound effect, potentially increasing the frequency of seizures. Your doctor will guide you on how to safely and gradually reduce the dosage if necessary.

FAQs

For how long do I need to take TOPAZ 50MG TABLET 15'S?

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The dose and duration of this medicine will depend on your doctor’s advice. TOPAZ 50MG TABLET 15'S does not cure your condition (seizures/migraine) but prevents them from occurring. So, you may have to keep taking it for months or years depending on improvement in your symptoms and side effects that may occur.

Is TOPAZ 50MG TABLET 15'S good for anxiety?

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TOPAZ 50MG TABLET 15'S is not indicated for the treatment of anxiety. Please consult your doctor before taking the medicine.

What are the serious side effects of TOPAZ 50MG TABLET 15'S?

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Serious side effects of TOPAZ 50MG TABLET 15'S are rare. The serious effects of TOPAZ 50MG TABLET 15'S may include glaucoma (difficulty in seeing, eye pain, and blurred vision), kidney stones (sharp pain in your sides or lower back), and metabolic acidosis (tiredness, loss of appetite, irregular and faint heartbeat). Other serious side effects of TOPAZ 50MG TABLET 15'S could be suicidal thoughts and insufficient sweating (some children taking TOPAZ 50MG TABLET 15'S may not sweat enough in hot weather, causing their body temperatures to rise).

I am taking valproic acid for fits. Will TOPAZ 50MG TABLET 15'S interfere with the working of valproic acid? Can this combination be taken?

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TOPAZ 50MG TABLET 15'S does not interfere with the working of valproic acid, but it increases the risk of getting excess levels of ammonia in the blood (hyperammonemia). Increased levels of ammonia in the blood can be dangerous and may cause difficulty in thinking, remembering information, or solving problems. It may also decrease your alertness and make you feel very sleepy with low energy. Immediately inform your doctor if you notice these symptoms. It is important to know that, in rare cases, TOPAZ 50MG TABLET 15'S alone can cause hyperammonemia.

Can TOPAZ 50MG TABLET 15'S be used in children?

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Yes, TOPAZ 50MG TABLET 15'S is used for seizures in children more than 2 years of age. However, because of the lack of any reports, this medicine is not recommended to be used in children for migraines.

Since I have started using TOPAZ 50MG TABLET 15'S people are saying that I have lost weight. Is it because of TOPAZ 50MG TABLET 15'S or something else for which I should get investigated?

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It could be due to TOPAZ 50MG TABLET 15'S because TOPAZ 50MG TABLET 15'S commonly causes weight loss probably due to a decrease in appetite. If you still have any doubts, talk to your doctor who will advise you appropriately.

References

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Topiramate. High Wycombe, Bucks: Janssen-Cilag Ltd.; 1995. (online) Available from:

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Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Topiramate. [Updated 2020 Jan 20]. (online) Available from:

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Topiramate. Gurabo, Puerto Rico: Janssen Ortho; 2012. (online) Available from:

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Central Drugs Standard Control Organisation (CDSCO). (online) Available from:

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Topiramate [Prescribing Information]. 2012. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2009. (online) Available from:

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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