TRAZINE H TABLET 10'S

How TRAZINE H TABLET 10'S Works

• TRAZINE H TABLET 10'S is a combination medication designed to manage hypertension, commonly known as high blood pressure. It combines two active ingredients: Hydrochlorothiazide and Losartan Potassium. Each component works through a distinct mechanism to lower blood pressure effectively.
• Hydrochlorothiazide is a thiazide diuretic, often referred to as a 'water pill.' It primarily acts on the kidneys to reduce sodium and water reabsorption back into the bloodstream. By inhibiting the sodium-chloride symporter in the distal convoluted tubule of the nephron, hydrochlorothiazide increases the excretion of sodium and chloride in the urine. As sodium and water are excreted, the volume of blood circulating in the body decreases. This reduction in blood volume leads to a decrease in cardiac output and overall blood pressure. Additionally, long-term use of thiazide diuretics can cause vasodilation (widening of blood vessels), further contributing to lower blood pressure.
• Losartan Potassium belongs to a class of drugs called angiotensin II receptor blockers (ARBs). Angiotensin II is a hormone that causes blood vessels to constrict, leading to increased blood pressure. It also stimulates the release of aldosterone, which promotes sodium and water retention by the kidneys. Losartan works by selectively blocking the angiotensin II receptors, particularly the AT1 receptor, found in various tissues, including blood vessels and the adrenal gland. By blocking these receptors, Losartan prevents angiotensin II from exerting its vasoconstricting effects, allowing blood vessels to relax and widen. This vasodilation reduces blood pressure. Furthermore, by blocking angiotensin II's action on the adrenal gland, Losartan reduces aldosterone release, promoting sodium and water excretion and further lowering blood pressure.
• The synergistic effect of combining hydrochlorothiazide and losartan potassium provides a comprehensive approach to managing hypertension. Hydrochlorothiazide reduces blood volume, while losartan prevents blood vessel constriction. Together, they effectively lower blood pressure, reducing the risk of cardiovascular events such as stroke, heart attack, and kidney damage. It is crucial to take TRAZINE H TABLET 10'S as prescribed by your healthcare provider and to adhere to any lifestyle modifications recommended, such as diet and exercise, to achieve optimal blood pressure control.

Possible side effects of TRAZINE H TABLET may include: * **Common:** Drowsiness, dizziness, headache, nausea, vomiting, dry mouth, constipation, blurred vision. * **Uncommon:** Confusion, restlessness, sleep disturbances, tremors, muscle weakness, skin rash, itching, increased sweating, ringing in the ears (tinnitus), changes in heart rate, difficulty urinating, changes in libido. * **Rare:** Severe allergic reaction (anaphylaxis), liver problems, blood disorders, seizures, neuroleptic malignant syndrome (NMS). **Note:** This is not an exhaustive list. If you experience any unusual or severe symptoms, consult your doctor immediately.

• If you miss a dose of TRAZINE H TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep TRAZINE H TAB 1X10 away from the reach of children and pets.
• Store TRAZINE H TAB 1X10 at room temperature.

• Take TRAZINE H TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as it can affect the effectiveness and safety of the medication. It's crucial to adhere to the prescribed regimen to manage your condition effectively.
• If you miss a dose of TRAZINE H TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up, as this can increase the risk of side effects. Consistency is key for optimal results.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting TRAZINE H TABLET 10'S. Certain substances can interact with TRAZINE H TABLET 10'S, potentially affecting its efficacy or increasing the risk of adverse reactions. A comprehensive medication history ensures safe and effective treatment.
• Store TRAZINE H TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage helps maintain the integrity and potency of the medication, ensuring it remains effective until its expiration date. Check the expiration date before use and discard any expired medication safely.
• Be aware of potential side effects associated with TRAZINE H TABLET 10'S, such as dizziness, drowsiness, or gastrointestinal upset. If you experience any persistent or bothersome side effects, contact your doctor immediately. They can provide guidance on managing these effects or adjust your treatment plan if necessary. Regular monitoring and communication with your healthcare provider are essential for safe medication use.

• TRAZINE H TABLET 10'S is generally safe to take with or without food. However, if you experience stomach upset, taking it with food may help.
• Avoid consuming large amounts of grapefruit juice while taking TRAZINE H TABLET 10'S, as it may increase the levels of the medication in your bloodstream.