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Composition
Content Reviewed By:
Dr. Manoj Shah
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Most side effects are temporary and resolve as your body adapts to the medication. If they continue or cause concern, seek medical advice. Common side effects of TRESIBA FLEX PEN 3 ML include:

Liver Function
CautionTRESIBA FLEX PEN 3 ML should be used with caution in patients with liver disease. Dose adjustment of TRESIBA FLEX PEN 3 ML may be needed. Please consult your doctor.
TRESIBA FLEX PEN 3 ML is an ultralong-acting type of insulin used to control high blood sugar in adults and children (as young as 1 year of age) with type 1 and type 2 diabetes mellitus. TRESIBA FLEX PEN 3 ML works like the insulin that is normally produced by the body and helps move sugar from the blood into other body tissues where it is used for energy production. Also, it stops the liver from producing more sugar and this helps to normalize the blood sugar levels.
TRESIBA FLEX PEN 3 ML is injected just below the skin (subcutaneously). Your doctor will train you on the correct method and the areas (abdomen or stomach, thighs, arms, hips, or buttocks) where you should inject it. It is advised that the site of injection should be changed within the chosen area of skin, for every dose. For example, if you have been advised to inject it into the skin of your stomach, avoid puncturing the same point on your stomach every day. Rather, inject the needle at a site that is slightly away, say around 1cm, from the previous injection. You can also consider switching sides while injecting, like choosing the right side on one day and the left side on the next day. This way, you can reduce the complications associated with repeated injections in the same site such as thickening of the fat tissue below the skin known as lipodystrophy, irritation, pain etc. After one to two weeks, you should move to another area of your body (eg. from the stomach to the arms or thighs) as advised by your doctor. Consult your doctor if you face any problems while injecting TRESIBA FLEX PEN 3 ML.
Insulin glargine and TRESIBA FLEX PEN 3 ML are both man-made versions of human insulin used to manage diabetes, however, they are different in some aspects. Insulin glargine is a long-acting insulin that typically lasts about 24 hours and helps maintain adequate blood sugar control for an entire day. Whereas, TRESIBA FLEX PEN 3 ML is an ultralong-acting insulin that can last longer (up to 42 hours) and helps control blood sugar levels for more than a day.
Both TRESIBA FLEX PEN 3 ML and insulin detemir are long-acting insulins with almost similar effectiveness and safety. The only difference is that TRESIBA FLEX PEN 3 ML has the longest duration of action (more than 40 hours) and this helps to maintain steady blood sugar levels throughout this duration. Some studies have reported that TRESIBA FLEX PEN 3 ML may have a slightly lesser risk of hypoglycemia.
TRESIBA FLEX PEN 3 ML can be safely used in combination with other diabetes medicines or fast-acting insulins if prescribed by the doctor. Take it in the dose and duration advised by your doctor to get maximum benefit. However, taking thiazolidinediones (TZDs), like pioglitazone, with TRESIBA FLEX PEN 3 ML may cause heart failure in some people. This can happen even if you have never had heart failure or heart problems. In case you already have heart failure, it may get worse on taking TZDs with TRESIBA FLEX PEN 3 ML. Let your doctor know about all the other medicines, particularly any other diabetes medicines you are taking because they may affect, or be affected by, this medicine. Inform your doctor if you have or ever had any heart problems.
Your doctor will advise certain lifestyle changes and you must adhere to them. Stay active and exercise regularly. Avoid missing meals and monitor your blood sugar levels. You may consult a dietician and follow a diet chart that suits you best. Do not drive or operate heavy machinery until you know how TRESIBA FLEX PEN 3 ML affects you. Do not drink alcohol as it may cause some undesirable side effects like dizziness. Tell your doctor about all the other medicines that you are taking as they may affect your dosage.
TRESIBA FLEX PEN 3 ML can help with daily management of diabetes. However, you may still need to use short-acting insulin to treat spikes in your blood sugar levels and diabetic ketoacidosis (a dangerous buildup of acids in your blood).
Yes, TRESIBA FLEX PEN 3 ML is basal insulin. There are three types of basal insulin currently available: Glargine, Detemir, and Degludec. The pharmacies sell these under different brand names. Basal insulin is a slow-acting type of insulin. People take it between mealtimes and before bedtime to control blood sugar outside of eating.
Long-acting insulins are also called basal or background insulins. They keep working in the background to keep your blood sugar under control throughout your daily routine. They’re absorbed into your body over a 24-hour period. Therefore, they keep blood sugar levels lowered for longer than short-acting insulins do.
Yes, TRESIBA FLEX PEN 3 ML may cause weight gain in some patients. This may be due to the anabolic effect of insulin which promotes the storage of glucose and fat.
No, TRESIBA FLEX PEN 3 ML by itself does not raise your blood sugar. However, if you stop taking TRESIBA FLEX PEN 3 ML, miss a dose, or take a dose lower than what is prescribed, your blood sugar levels may rise. Furthermore, if the person has any other condition along with diabetes, especially infections, stress, irregular meals, or reduced activity levels, it may also lead to high blood sugar levels. As a result, their requirement for TRESIBA FLEX PEN 3 ML may increase further. Consult your doctor to know about any dose changes if you have been facing any of these issues or if your blood sugar levels are not controlled.
Tresiba Flex Pen 3 ML contains Insulin Degludec 100 IU.
Tresiba Flex Pen 3 ML is listed at Rs. 1650.7 on Medkart. Prices can change — check the product page for the current price and pack size.
The dose of Tresiba Flex Pen 3 ML depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.
A generic medicine is one with the same active composition as the branded product — for Tresiba Flex Pen 3 ML that is Insulin Degludec 100 IU. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Tresiba Flex Pen 3 ML.
Yes. Tresiba Flex Pen 3 ML requires a valid doctor's prescription.
Tresiba Flex Pen 3 ML is manufactured by Novo Nordisk India Pvt Ltd.
Tresiba Flex Pen 3 ML is supplied as a injection and is taken by the parenteral route.
Whether Tresiba Flex Pen 3 ML can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Tresiba Flex Pen 3 ML on your own.
The timing of Tresiba Flex Pen 3 ML depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.
No. Tresiba Flex Pen 3 ML is a prescription medicine and should only be taken on a doctor's advice.
Store Tresiba Flex Pen 3 ML in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.
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