TRIBEN AD LOTION 120 ML

How TRIBEN AD LOTION 120 ML Works

• TRIBEN AD LOTION 120 ML is a topical medication formulated to treat fungal infections of the skin, such as athlete's foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis). Its effectiveness stems from the synergistic action of its active ingredients: Terbinafine, Ofloxacin, Ornidazole, and Clobetasol Propionate. Understanding how each of these components works is crucial to appreciating the overall mechanism of action of TRIBEN AD LOTION.
• Terbinafine is an allylamine antifungal that inhibits the synthesis of ergosterol, a crucial component of fungal cell membranes. Specifically, Terbinafine blocks squalene epoxidase, an enzyme necessary for ergosterol production. By disrupting ergosterol synthesis, Terbinafine weakens the fungal cell membrane, leading to increased permeability and leakage of cellular contents. This ultimately inhibits fungal growth and causes cell death. Its broad-spectrum antifungal activity makes it effective against a wide range of dermatophytes, the fungi responsible for many skin infections.
• Ofloxacin is a broad-spectrum fluoroquinolone antibiotic that targets bacterial infections. While TRIBEN AD LOTION is primarily used for fungal infections, Ofloxacin addresses secondary bacterial infections that may arise due to skin damage from the fungal infection or scratching. Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By blocking these enzymes, Ofloxacin prevents bacterial cells from multiplying, effectively controlling the bacterial component of the infection.
• Ornidazole is a nitroimidazole antibiotic and antiprotozoal agent. Similar to Ofloxacin, Ornidazole targets bacteria and certain protozoa that might complicate the primary fungal infection. Ornidazole's mechanism of action involves the reduction of its nitro group by anaerobic bacteria and protozoa. This reduction creates reactive intermediates that damage DNA and other essential cellular components, leading to cell death. The inclusion of Ornidazole helps to ensure comprehensive control over potential polymicrobial infections.
• Clobetasol Propionate is a highly potent topical corticosteroid. It works by reducing inflammation, itching, and redness associated with skin infections. Clobetasol Propionate binds to intracellular glucocorticoid receptors, which then regulate the transcription of various genes involved in the inflammatory response. This leads to decreased production of inflammatory mediators, such as cytokines and prostaglandins. By suppressing inflammation, Clobetasol Propionate provides symptomatic relief and promotes healing of the affected skin. However, it is important to use Clobetasol Propionate sparingly and as directed by a healthcare professional due to the potential for side effects associated with prolonged or excessive use of corticosteroids.
• In summary, TRIBEN AD LOTION combines the antifungal power of Terbinafine with the antibacterial and antiprotozoal actions of Ofloxacin and Ornidazole, and the anti-inflammatory effect of Clobetasol Propionate. This multifaceted approach effectively targets fungal infections while addressing potential secondary bacterial infections and alleviating associated symptoms, leading to faster healing and improved patient comfort. It is crucial to use this medication as prescribed by a healthcare professional to maximize its benefits and minimize the risk of side effects. Consistent application and adherence to the prescribed duration of treatment are essential for achieving optimal results.

TRIBEN AD LOTION 120 ML, like all medications, can cause side effects, although not everyone experiences them. Common side effects may include application site reactions such as burning, stinging, itching, irritation, redness, dryness, or peeling. Some individuals might experience allergic reactions like rash, hives, or swelling. Less common side effects could involve folliculitis (inflammation of hair follicles), skin thinning, changes in skin color, or secondary skin infections. If any of these side effects persist or worsen, or if you notice any other unusual symptoms, discontinue use and consult your doctor or pharmacist immediately. This is not an exhaustive list, and it's essential to read the product leaflet for a complete overview. Rarely, systemic absorption can lead to more serious side effects. Consult your healthcare provider for detailed information and management of potential side effects.

• If you forget to apply TRIBEN AD LOTION, apply it as soon as you remember. However, if it is almost time for your next application, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.

• Keep TRIBEN AD LOTION 120ML away from the reach of children and pets.
• Store TRIBEN AD LOTION 120ML at room temperature.

• **Consistency is Key:** Apply TRIBEN AD LOTION 120 ML regularly as directed by your doctor, even if your symptoms improve. Skipping applications can lead to a recurrence of the infection. Typically, it is applied twice daily for optimal results, but always adhere to your doctor's specific instructions regarding frequency and duration of treatment. This consistency ensures the medication effectively combats the fungal or bacterial infection.
• **Clean and Dry Thoroughly:** Before applying TRIBEN AD LOTION 120 ML, gently wash the affected area with a mild, unscented soap and pat it completely dry. Moisture can exacerbate infections and hinder the lotion's effectiveness. Ensure that the skin folds, such as those in the groin area or between toes, are especially dry before applying the lotion. Allow the area to air dry for a few minutes after washing for best results.
• **Apply a Thin Layer:** Use only a thin layer of TRIBEN AD LOTION 120 ML to cover the affected area. Applying too much lotion won't make it work faster or better and can lead to unnecessary side effects such as skin irritation or increased absorption into the body. Gently massage the lotion into the skin until it is fully absorbed. Wash your hands thoroughly after application unless you are treating your hands.
• **Avoid Occlusive Dressings:** Unless specifically instructed by your doctor, avoid covering the treated area with airtight bandages or dressings. These can create a moist environment that promotes fungal growth and reduces the lotion's efficacy. Loose-fitting clothing is preferable to allow the skin to breathe. If a dressing is required, use a breathable, non-occlusive bandage.
• **Complete the Full Course:** It's crucial to complete the entire course of treatment with TRIBEN AD LOTION 120 ML, even if your symptoms disappear within a few days. Prematurely stopping the medication can result in the infection returning, potentially stronger and more resistant to treatment. Follow your doctor's instructions meticulously, and if you have any concerns or experience any side effects, consult your healthcare provider promptly. Store the lotion in a cool, dry place away from direct sunlight and out of reach of children.

• TRIBEN AD LOTION 120 ML is for external use only and is unlikely to interact with food. However, if you experience any unusual symptoms after applying the lotion, consult your doctor.