TRICINOD 10/12.5MG TABLET 15'S

How TRICINOD 10/12.5MG TABLET 15'S Works

• TRICINOD 10/12.5MG TABLET 15'S is a combination medication designed to effectively manage hypertension, or high blood pressure. It combines two active ingredients: Cilnidipine and Chlorthalidone, each working through different mechanisms to lower blood pressure and reduce the risk of cardiovascular events.
• Cilnidipine is a dihydropyridine calcium channel blocker. Calcium channel blockers work by preventing calcium from entering the smooth muscle cells of blood vessel walls. This influx of calcium is normally responsible for causing these muscles to contract, leading to vasoconstriction (narrowing of blood vessels). By blocking calcium channels, Cilnidipine causes the smooth muscles to relax, resulting in vasodilation (widening of blood vessels). This vasodilation reduces peripheral vascular resistance, the resistance the heart has to pump against, thereby lowering blood pressure. Cilnidipine is also unique because it acts on both L-type and N-type calcium channels. Its action on N-type calcium channels may provide additional benefits in protecting the kidneys and reducing sympathetic nerve activity, which can further contribute to blood pressure control.
• Chlorthalidone is a thiazide-like diuretic, often referred to as a water pill. It works primarily in the kidneys by inhibiting the reabsorption of sodium and chloride in the distal convoluted tubule. By blocking this reabsorption, Chlorthalidone increases the amount of sodium and chloride excreted in the urine. Water follows sodium, so this also increases urine volume. This increased excretion of fluid reduces the overall blood volume, which in turn lowers blood pressure. In addition to its diuretic effect, Chlorthalidone also has a long-term effect on blood vessels, making them more relaxed and responsive to blood pressure regulation. It's crucial to note that diuretics can also lead to potassium loss, so monitoring potassium levels is important during treatment.
• The synergistic action of Cilnidipine and Chlorthalidone provides a comprehensive approach to blood pressure management. Cilnidipine reduces vascular resistance by relaxing blood vessels, while Chlorthalidone reduces blood volume by increasing fluid excretion. This combination addresses multiple factors contributing to hypertension, leading to more effective blood pressure control than either drug could achieve alone. By effectively lowering blood pressure, TRICINOD 10/12.5MG TABLET 15'S helps to reduce the risk of serious complications associated with hypertension, such as heart attack, stroke, kidney disease, and heart failure. Regular monitoring by a healthcare professional is essential to ensure the medication is working effectively and to manage any potential side effects.

Possible side effects of TRICINOD 10/12.5MG TABLET may include: * **Common:** Headache, dizziness, fatigue, nausea, vomiting, diarrhea, constipation, abdominal pain, dry mouth, cough, sore throat, nasal congestion, muscle aches, back pain, insomnia. * **Uncommon:** Anxiety, nervousness, tremor, palpitations, increased heart rate, rash, itching, swelling, blurred vision, ringing in the ears, changes in taste, difficulty urinating, electrolyte imbalance, liver problems. * **Rare:** Severe allergic reaction (anaphylaxis), Stevens-Johnson syndrome, toxic epidermal necrolysis, angioedema, heart attack, stroke, seizures, hallucinations, psychosis. **Note:** This is not an exhaustive list. If you experience any unusual or severe side effects, stop taking TRICINOD and consult your doctor immediately.

• If you miss a dose of TRICINOD 10/12.5MG TABLET 15'S, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep TRICINOD 10/12.5MG TAB 1X15 away from the reach of children and pets.
• Store TRICINOD 10/12.5MG TAB 1X15 at room temperature.

• Take TRICINOD 10/12.5MG TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medicine without consulting them, as this could affect your blood pressure control and overall health. It is typically taken once daily, with or without food, but try to take it at the same time each day to maintain consistent blood levels.
• Monitor your blood pressure regularly while taking TRICINOD 10/12.5MG TABLET 15'S. Keep a record of your readings and share them with your doctor during your check-ups. This helps them assess the effectiveness of the medication and make any necessary adjustments to your treatment plan. A home blood pressure monitor can be a valuable tool.
• Be mindful of potential side effects. TRICINOD 10/12.5MG TABLET 15'S may cause dizziness, lightheadedness, or fatigue, especially when you first start taking it or after a dosage increase. Rise slowly from a sitting or lying position to minimize these effects. If side effects persist or worsen, inform your doctor.
• Maintain a healthy lifestyle while on TRICINOD 10/12.5MG TABLET 15'S. This includes following a balanced diet low in sodium and saturated fats, engaging in regular physical activity (as approved by your doctor), maintaining a healthy weight, and limiting alcohol consumption. These lifestyle modifications can significantly enhance the effectiveness of the medication and improve your overall cardiovascular health.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. Certain substances can interact with TRICINOD 10/12.5MG TABLET 15'S, potentially affecting its efficacy or increasing the risk of side effects. This includes over-the-counter medications, as well as prescription drugs. Always keep your doctor fully informed about your complete medication list to ensure safe and effective treatment.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports healthy blood volume and can help prevent dizziness or lightheadedness associated with blood pressure medications like TRICINOD 10/12.5MG TABLET 15'S. Aim for at least 8 glasses of water daily, unless otherwise directed by your doctor.

• TRICINOD 10/12.5MG TABLET 15'S can be taken with or without food. However, it is best to take it at a consistent time each day to maintain steady blood levels of the medication. Avoid excessive consumption of grapefruit or grapefruit juice, as it may interact with the medication and increase the risk of side effects. Discuss your diet with your doctor or pharmacist to ensure there are no specific food interactions you need to be concerned about.