TRIGLIMISAVE 1 HS PLUS TABLET 10'S
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TRIGLIMISAVE 1 HS PLUS TABLET 10'STRIGLIMISAVE 1 HS PLUS TABLET 10'STRIGLIMISAVE 1 HS PLUS TABLET 10'S
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TRIGLIMISAVE 1 HS PLUS TABLET 10'S

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TRIGLIMISAVE 1 HS PLUS TABLET 10'S

By ERIS LIFESCIENCES LIMITED

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118.27

₹100.53

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About TRIGLIMISAVE 1 HS PLUS TABLET 10'S

  • TRIGLIMISAVE 1 HS PLUS TABLET 10'S is a combination medicine specifically designed to manage blood sugar levels in adults with type 2 diabetes. It combines three active ingredients to provide comprehensive glycemic control: Glimepiride, Metformin, and Pioglitazone. This medication is intended to be taken once daily at bedtime (HS - hora somni), offering convenience and potentially improving adherence.
  • Glimepiride belongs to the sulfonylurea class of drugs. It works by stimulating the pancreas to release more insulin. Insulin helps lower blood sugar by enabling glucose to move from the blood into cells, where it's used for energy. By increasing insulin secretion, glimepiride effectively reduces elevated blood sugar levels, particularly after meals.
  • Metformin is a biguanide that works primarily by decreasing glucose production in the liver and improving the body's sensitivity to insulin. It reduces the amount of glucose the liver releases into the bloodstream and helps cells utilize insulin more effectively. Unlike some diabetes medications, metformin typically does not cause weight gain and may even promote modest weight loss in some individuals.
  • Pioglitazone is a thiazolidinedione (TZD) that enhances insulin sensitivity in peripheral tissues such as muscle and fat. It works by activating PPARγ (peroxisome proliferator-activated receptor gamma), a nuclear receptor that regulates genes involved in glucose and lipid metabolism. By improving insulin sensitivity, pioglitazone helps lower blood sugar levels and can also have beneficial effects on lipid profiles.
  • TRIGLIMISAVE 1 HS PLUS is typically prescribed when diet and exercise alone are insufficient to control blood sugar levels in patients with type 2 diabetes. It is important to use this medication as part of a comprehensive diabetes management plan that includes regular monitoring of blood sugar, a healthy diet, and regular physical activity. Patients should discuss their complete medical history and all other medications they are taking with their doctor before starting TRIGLIMISAVE 1 HS PLUS.

Uses of TRIGLIMISAVE 1 HS PLUS TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling blood sugar levels after meals
  • Management of insulin resistance associated with polycystic ovary syndrome (PCOS)
  • Reducing the risk of heart disease (in some cases)
  • Used in combination with other diabetes medications

How TRIGLIMISAVE 1 HS PLUS TABLET 10'S Works

  • TRIGLIMISAVE 1 HS PLUS TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: glimepiride, metformin, and pioglitazone, each working through different mechanisms to control blood sugar levels. This multi-pronged approach addresses various aspects of glucose metabolism, providing comprehensive glycemic control.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the bloodstream into cells, where it is used for energy. By increasing insulin secretion, glimepiride helps lower blood sugar levels, particularly after meals. It works best when taken consistently and in conjunction with a healthy diet and regular exercise.
  • Metformin, a biguanide, primarily works by reducing glucose production in the liver. The liver can sometimes produce excessive amounts of glucose, especially in people with type 2 diabetes. Metformin also enhances insulin sensitivity, meaning that cells become more responsive to insulin, allowing them to take up glucose more efficiently. Additionally, metformin slows down the absorption of glucose from the intestines after a meal. This triple action helps to control blood sugar levels throughout the day.
  • Pioglitazone, a thiazolidinedione (TZD), improves insulin sensitivity in muscle and fat tissues. It helps insulin work more effectively, allowing glucose to enter cells more readily. Pioglitazone also reduces glucose production in the liver, contributing to overall blood sugar control. It may take several weeks to see the full effects of pioglitazone as it gradually improves insulin sensitivity.
  • By combining these three medications, TRIGLIMISAVE 1 HS PLUS TABLET 10'S targets multiple pathways involved in blood sugar regulation. This comprehensive approach can lead to better glycemic control compared to using a single medication. It's important to take this medication as prescribed by your doctor and to follow a healthy lifestyle, including a balanced diet and regular physical activity, to maximize its effectiveness. Regular monitoring of blood sugar levels is also crucial to ensure the medication is working properly and to adjust the dosage if needed.

Side Effects of TRIGLIMISAVE 1 HS PLUS TABLET 10'SArrow

Possible side effects of TRIGLIMISAVE 1 HS PLUS Tablet may include: Hypoglycemia (low blood sugar), Nausea, Vomiting, Diarrhea, Abdominal pain, Headache, Dizziness, Weakness, Metallic taste, Skin rash, Itching, Weight gain, Edema (swelling), Liver problems, Changes in blood cell counts. This is not an exhaustive list, and it's important to consult your doctor if you experience any unusual or severe symptoms while taking this medication.

Safety Advice for TRIGLIMISAVE 1 HS PLUS TABLET 10'SArrow

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Allergies

Allergies

Do not use this medicine if you are allergic to it.

Dosage of TRIGLIMISAVE 1 HS PLUS TABLET 10'SArrow

  • The recommended dosage of TRIGLIMISAVE 1 HS PLUS TABLET 10'S is highly individualized and depends on several factors, including your blood glucose levels, kidney function, other medical conditions, and response to treatment. Your physician will determine the appropriate dosage for you based on these factors. Typically, TRIGLIMISAVE 1 HS PLUS TABLET 10'S is taken once daily, preferably with the evening meal or as directed by your doctor. It is crucial to adhere strictly to the prescribed dosage and timing.
  • Do not adjust the dosage on your own without consulting your healthcare provider. Self-adjusting the dosage can lead to either inadequate blood glucose control or an increased risk of side effects such as hypoglycemia (low blood sugar). Regular monitoring of your blood glucose levels is essential while taking TRIGLIMISAVE 1 HS PLUS TABLET 10'S to assess its effectiveness and guide dosage adjustments. Your doctor may also recommend periodic blood tests to evaluate your kidney function and overall health.
  • In some cases, your doctor may start you on a low dose of TRIGLIMISAVE 1 HS PLUS TABLET 10'S and gradually increase it over time to minimize the risk of side effects. This titration approach allows your body to adjust to the medication. If you miss a dose of TRIGLIMISAVE 1 HS PLUS TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • It is important to inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with TRIGLIMISAVE 1 HS PLUS TABLET 10'S. Certain medications can either increase or decrease the blood glucose-lowering effects of TRIGLIMISAVE 1 HS PLUS TABLET 10'S, requiring dosage adjustments. Take 'TRIGLIMISAVE 1 HS PLUS TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

  • If you miss a dose of TRIGLIMISAVE 1 HS PLUS TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

  • Keep TRIGLIMISAVE 1 HS PLUS TAB 1X10 away from the reach of children and pets.
  • Store TRIGLIMISAVE 1 HS PLUS TAB 1X10 at room temperature.

Benefits of TRIGLIMISAVE 1 HS PLUS TABLET 10'SArrow

  • TRIGLIMISAVE 1 HS PLUS Tablet 10's is a combination medicine used to treat type 2 diabetes mellitus. It is designed for individuals whose blood sugar levels are not adequately controlled by diet, exercise, and other anti-diabetic medications alone. The synergistic action of its components helps manage blood glucose more effectively, leading to improved overall health and well-being.
  • The primary benefit of TRIGLIMISAVE 1 HS PLUS is its ability to lower blood sugar levels. By combining different mechanisms of action, this medication helps to reduce both fasting and postprandial (after-meal) blood glucose levels. This is crucial for preventing the long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular diseases.
  • TRIGLIMISAVE 1 HS PLUS improves insulin sensitivity, allowing your body to use insulin more effectively. This is particularly beneficial for individuals with insulin resistance, a common characteristic of type 2 diabetes, where the body's cells do not respond properly to insulin. By enhancing insulin sensitivity, the medication helps to facilitate the uptake of glucose from the bloodstream into cells, thereby lowering blood sugar levels.
  • This medication helps in regulating the release of glucose from the liver. In individuals with diabetes, the liver may produce excessive amounts of glucose, contributing to high blood sugar levels. TRIGLIMISAVE 1 HS PLUS helps to control hepatic glucose production, preventing surges in blood sugar, especially during fasting periods or overnight.
  • TRIGLIMISAVE 1 HS PLUS can also assist in weight management. Some of its components have been shown to have a neutral or even positive effect on body weight, which is an important consideration for many individuals with type 2 diabetes who may be overweight or obese. Maintaining a healthy weight is crucial for managing blood sugar levels and reducing the risk of diabetes-related complications.
  • The convenience of taking a single tablet containing multiple active ingredients simplifies the treatment regimen. This can improve adherence to medication, as patients are more likely to take their medication as prescribed when it involves fewer pills. Better adherence leads to better control of blood sugar levels and improved health outcomes.
  • By effectively managing blood sugar levels, TRIGLIMISAVE 1 HS PLUS reduces the risk of long-term complications associated with diabetes. This includes a lower risk of cardiovascular events such as heart attack and stroke, as well as a reduced likelihood of developing nerve damage, kidney disease, and vision problems. Preventing these complications can significantly improve the quality of life and overall health of individuals with diabetes.
  • TRIGLIMISAVE 1 HS PLUS can lead to an improved sense of well-being. By maintaining stable blood sugar levels, patients may experience fewer symptoms of hyperglycemia (high blood sugar), such as fatigue, excessive thirst, and frequent urination. This can result in increased energy levels, better sleep, and an overall improvement in daily functioning.

How to use TRIGLIMISAVE 1 HS PLUS TABLET 10'SArrow

  • TRIGLIMISAVE 1 HS PLUS is a combination medicine specifically designed to manage type 2 diabetes. It's crucial to use it correctly to get the maximum benefit. Always follow your doctor's instructions precisely regarding dosage and timing. Typically, this medication is taken once daily, preferably at night, just before bedtime, as indicated by 'HS' (hora somni) in its name. This timing helps align the medication's action with the body's natural circadian rhythms and glucose metabolism.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break it, as this can affect how the medication is released and absorbed. Taking it at the same time each night will help you remember and maintain a consistent level of medication in your body. Consistency is key to effectively managing your blood sugar levels.
  • This medication is intended to be used in conjunction with lifestyle changes, including a balanced diet and regular exercise. Continue to follow your diet and exercise plan as directed by your healthcare provider. It is very important to adhere to a healthy lifestyle while taking TRIGLIMISAVE 1 HS PLUS.
  • Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. Keep a record of your blood sugar readings and share them with your doctor during your appointments. This information will help your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, or herbal products you are taking before starting TRIGLIMISAVE 1 HS PLUS. Some medications can interact with this drug, potentially affecting its efficacy or increasing the risk of side effects. It is important to make your doctor aware of your entire medication list to avoid any complications.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one. If you have concerns about a missed dose, consult your doctor or pharmacist.
  • Be aware of potential side effects, such as hypoglycemia (low blood sugar), nausea, or gastrointestinal issues. If you experience any severe or persistent side effects, contact your doctor immediately. It's vital to recognize the symptoms of low blood sugar (such as sweating, shaking, rapid heartbeat, and confusion) and know how to treat it quickly (usually with fast-acting carbohydrates).
  • Store TRIGLIMISAVE 1 HS PLUS at room temperature, away from moisture and heat. Keep it out of reach of children. Properly dispose of any unused medication according to your local regulations.
  • Attend all scheduled appointments with your doctor and other healthcare providers. These visits are crucial for monitoring your condition and adjusting your treatment plan as needed. Do not stop taking TRIGLIMISAVE 1 HS PLUS without consulting your doctor, even if you feel better. Stopping the medication abruptly can lead to uncontrolled blood sugar levels.

Quick Tips for TRIGLIMISAVE 1 HS PLUS TABLET 10'SArrow

  • Take TRIGLIMISAVE 1 HS PLUS TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This medication is typically taken once daily, preferably at bedtime, to maximize its effectiveness in controlling blood sugar levels overnight. Following the prescribed regimen ensures optimal therapeutic benefits and minimizes potential side effects.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting TRIGLIMISAVE 1 HS PLUS TABLET 10'S. This is crucial to avoid potential drug interactions that could affect the efficacy of TRIGLIMISAVE 1 HS PLUS TABLET 10'S or increase the risk of adverse effects. Certain medications can either enhance or diminish the blood sugar-lowering effects of TRIGLIMISAVE 1 HS PLUS TABLET 10'S, requiring dosage adjustments or closer monitoring.
  • Monitor your blood sugar levels regularly as directed by your doctor while taking TRIGLIMISAVE 1 HS PLUS TABLET 10'S. Keeping a log of your blood sugar readings can help you and your healthcare provider assess how well the medication is working and make any necessary adjustments to your treatment plan. Regular monitoring also helps in detecting and managing hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar) promptly.
  • Follow a balanced diet and engage in regular physical activity while taking TRIGLIMISAVE 1 HS PLUS TABLET 10'S. This medication works best when combined with lifestyle modifications such as a healthy eating plan and consistent exercise routine. Focus on consuming whole grains, fruits, vegetables, and lean proteins, and aim for at least 30 minutes of moderate-intensity exercise most days of the week. These lifestyle changes can significantly improve blood sugar control and overall health.
  • Be aware of the symptoms of hypoglycemia (low blood sugar) and know how to treat it while taking TRIGLIMISAVE 1 HS PLUS TABLET 10'S. Symptoms of hypoglycemia may include shakiness, sweating, dizziness, hunger, confusion, and rapid heartbeat. If you experience these symptoms, consume a fast-acting source of sugar such as glucose tablets, fruit juice, or hard candy. It is important to carry a source of fast-acting sugar with you at all times, especially when exercising or traveling.

Food Interactions with TRIGLIMISAVE 1 HS PLUS TABLET 10'SArrow

  • TRIGLIMISAVE 1 HS PLUS TABLET 10'S is generally safe to take with food. However, it is best to take it at the same time each day to maintain consistent blood sugar levels. Avoid excessive alcohol consumption, as it can increase the risk of low blood sugar (hypoglycemia).

FAQs

What is TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

TRIGLIMISAVE 1 HS PLUS TABLET 10'S is a medication used to treat type 2 diabetes mellitus. It contains a combination of Glimepiride, Metformin, and Pioglitazone.

What is TRIGLIMISAVE 1 HS PLUS TABLET 10'S used for?Arrow

TRIGLIMISAVE 1 HS PLUS TABLET 10'S is used to control high blood sugar levels in people with type 2 diabetes mellitus, when diet and exercise alone are not enough.

How does TRIGLIMISAVE 1 HS PLUS TABLET 10'S work?Arrow

TRIGLIMISAVE 1 HS PLUS TABLET 10'S works in three different ways: it increases the amount of insulin released from the pancreas, makes the body more sensitive to insulin, and decreases the amount of glucose produced by the liver.

What are the common side effects of TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

Common side effects of TRIGLIMISAVE 1 HS PLUS TABLET 10'S include low blood sugar (hypoglycemia), nausea, diarrhea, and stomach upset.

How should I take TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

Take TRIGLIMISAVE 1 HS PLUS TABLET 10'S exactly as prescribed by your doctor. It is usually taken once daily, with food.

Is TRIGLIMISAVE 1 HS PLUS TABLET 10'S safe during pregnancy?Arrow

The safety of TRIGLIMISAVE 1 HS PLUS TABLET 10'S during pregnancy has not been established. Talk to your doctor if you are pregnant or planning to become pregnant.

Is it safe to drink alcohol while taking TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

It is not recommended to drink alcohol while taking TRIGLIMISAVE 1 HS PLUS TABLET 10'S as it can increase the risk of low blood sugar.

Can TRIGLIMISAVE 1 HS PLUS TABLET 10'S interact with other medications?Arrow

Yes, TRIGLIMISAVE 1 HS PLUS TABLET 10'S can interact with several other medications. Tell your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements.

How should I store TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

Store TRIGLIMISAVE 1 HS PLUS TABLET 10'S at room temperature, away from heat and moisture.

What happens if I miss a dose of TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

If you miss a dose of TRIGLIMISAVE 1 HS PLUS TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

Can TRIGLIMISAVE 1 HS PLUS TABLET 10'S cause weight gain?Arrow

Yes, TRIGLIMISAVE 1 HS PLUS TABLET 10'S can cause weight gain in some people. Talk to your doctor if you are concerned about weight gain while taking this medication.

Can TRIGLIMISAVE 1 HS PLUS TABLET 10'S cause kidney problems?Arrow

In rare cases, TRIGLIMISAVE 1 HS PLUS TABLET 10'S can cause kidney problems. Tell your doctor if you have a history of kidney disease.

Can TRIGLIMISAVE 1 HS PLUS TABLET 10'S cause heart problems?Arrow

Some studies have suggested that TRIGLIMISAVE 1 HS PLUS TABLET 10'S may increase the risk of heart problems. Talk to your doctor if you have a history of heart disease.

What is the difference between Glimisave MF and TRIGLIMISAVE 1 HS PLUS TABLET 10'S?Arrow

Glimisave MF contains Glimepiride and Metformin, while TRIGLIMISAVE 1 HS PLUS TABLET 10'S contains Glimepiride, Metformin, and Pioglitazone.

Can TRIGLIMISAVE 1 HS PLUS TABLET 10'S cause dizziness?Arrow

Yes, TRIGLIMISAVE 1 HS PLUS TABLET 10'S can cause dizziness in some people, especially when you first start taking it. If you experience dizziness, do not drive or operate machinery until you feel well.

References

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DrugBank: Gliclazide. This entry provides detailed chemical and pharmacological information about Gliclazide, one of the active ingredients in TRIGLIMISAVE 1 HS PLUS.

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DrugBank: Metformin. This entry provides detailed chemical and pharmacological information about Metformin, one of the active ingredients in TRIGLIMISAVE 1 HS PLUS.

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FDA: Metformin Hydrochloride Tablets, Extended Release. This is a sample FDA label that can be used to show how metformin is used to treat type 2 diabetes

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National Institutes of Health: Efficacy of triple therapy in patients with type 2 diabetes mellitus uncontrolled with metformin and sulfonylurea: A systematic review and meta-analysis

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Electronic Medicines Compendium (EMC): Gliclazide 80mg Tablets. This provides the Summary of Product Characteristics (SmPC) for a Gliclazide-containing medication, which is relevant to TRIGLIMISAVE 1 HS PLUS.

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Reviewed on 25-07-2023

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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