TRIZORYL 2MG TABLET 10'S

How TRIZORYL 2MG TABLET 10'S Works

• TRIZORYL 2MG TABLET contains Tizanidine, a muscle relaxant that works primarily by affecting the central nervous system. It is used to relieve muscle spasms caused by conditions like multiple sclerosis, spinal cord injury, or other musculoskeletal conditions. Here's a detailed explanation of how Tizanidine works:
• **Mechanism of Action:** Tizanidine is an alpha-2 adrenergic agonist. This means it binds to and activates alpha-2 adrenergic receptors located in the central nervous system, particularly in the spinal cord. These receptors play a crucial role in regulating the release of neurotransmitters.
• **Inhibition of Excitatory Neurotransmitters:** By activating alpha-2 adrenergic receptors, Tizanidine reduces the release of excitatory neurotransmitters like glutamate and aspartate from presynaptic neurons in the spinal cord. These neurotransmitters are responsible for transmitting signals that increase muscle tone and spasms.
• **Increased Presynaptic Inhibition:** Tizanidine enhances presynaptic inhibition of motor neurons. This means it reduces the excitability of neurons that control muscle movement, making them less likely to fire and trigger muscle contractions.
• **Reduced Polysynaptic Activity:** Tizanidine also decreases polysynaptic activity in the spinal cord. Polysynaptic reflexes involve multiple neurons and synapses and can contribute to muscle spasticity. By reducing this activity, Tizanidine helps to alleviate spasms.
• **Net Effect: Muscle Relaxation:** The combined effects of reduced excitatory neurotransmitter release, increased presynaptic inhibition, and decreased polysynaptic activity result in a reduction of muscle tone and a decrease in the frequency and severity of muscle spasms. This leads to muscle relaxation and improved mobility for individuals experiencing spasticity.
• **Impact on Pain:** While primarily a muscle relaxant, Tizanidine can also provide some pain relief. By reducing muscle spasms, it can indirectly alleviate pain associated with these spasms. Additionally, its action on alpha-2 adrenergic receptors can have a mild analgesic effect.
• **Important Considerations:** It's important to note that Tizanidine's effects are primarily symptomatic. It does not address the underlying cause of the muscle spasticity. Furthermore, Tizanidine can cause side effects such as drowsiness, dizziness, dry mouth, and low blood pressure. Therefore, it is crucial to use it under the guidance of a healthcare professional.

Common side effects of TRIZORYL 2MG TABLET may include drowsiness, dizziness, headache, blurred vision, nausea, vomiting, constipation, dry mouth, and urinary retention. Less common side effects may include confusion, agitation, hallucinations, skin rash, itching, swelling, and changes in heart rate. Rare but serious side effects include neuroleptic malignant syndrome (NMS), tardive dyskinesia, and severe allergic reactions. Contact your doctor immediately if you experience any serious side effects or symptoms that concern you.

• If you miss a dose of Trizoryl 2mg Tablet, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the one you missed.

• Keep TRIZORYL 2MG TAB 1X10 away from the reach of children and pets.
• Store TRIZORYL 2MG TAB 1X10 at room temperature.

• Take TRIZORYL 2MG TABLET exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. Consistency is key for optimal results in managing your condition. Skipping doses or taking it at inconsistent times can affect how well the medication works.
• TRIZORYL 2MG TABLET can sometimes cause drowsiness or dizziness. Avoid driving or operating heavy machinery until you know how the medication affects you. Your safety is important, and it's crucial to be fully alert when performing tasks that require concentration. If drowsiness persists, discuss it with your doctor.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking. Drug interactions can occur, potentially affecting the effectiveness of TRIZORYL 2MG TABLET or increasing the risk of side effects. Include both prescription and over-the-counter medications in your disclosure.
• Store TRIZORYL 2MG TABLET in a cool, dry place away from direct sunlight and moisture. Proper storage helps maintain the medication's effectiveness. Keep it out of reach of children and pets to prevent accidental ingestion. Do not store in the bathroom due to humidity.
• If you experience any unusual or severe side effects while taking TRIZORYL 2MG TABLET, contact your doctor immediately. Common side effects are usually mild, but if you have concerns like severe skin rashes, breathing difficulties, or persistent nausea, seek prompt medical attention. Do not wait for the symptoms to worsen.

• TRIZORYL 2MG TABLET 10'S is generally taken without regard to food. However, it's always best to follow your doctor's specific instructions. While there aren't known direct interactions, maintaining a consistent dietary pattern can aid in managing your condition effectively. Avoid large meals immediately before or after taking the medication, as this could potentially affect absorption.