VALANCE 250MG SOLUTION 100ML

How VALANCE 250MG SOLUTION 100ML Works

• VALANCE 250MG SOLUTION 100ML contains valproic acid as its active ingredient. Valproic acid is a broad-spectrum anticonvulsant and mood-stabilizing medication that works through several mechanisms to control seizures and stabilize mood. Its primary mechanism involves increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter that reduces neuronal excitability. By enhancing GABA's effects, valproic acid helps to calm overactive nerve cells and prevent the excessive firing that leads to seizures. Specifically, valproic acid inhibits GABA transaminase, the enzyme responsible for breaking down GABA, and it may also stimulate GABA synthesis, further boosting GABA concentrations.
• In addition to its GABAergic effects, valproic acid also impacts sodium and calcium channels in neurons. It inhibits voltage-gated sodium channels, which are crucial for the propagation of action potentials. By blocking these channels, valproic acid reduces the ability of neurons to fire rapidly and repetitively, thus preventing the spread of seizure activity. Furthermore, it modulates T-type calcium channels, which play a role in neuronal excitability and are implicated in certain types of seizures. By influencing these ion channels, valproic acid contributes to the stabilization of neuronal membranes and reduces the likelihood of seizure initiation and propagation.
• Beyond its anticonvulsant properties, valproic acid also acts as a mood stabilizer, although the precise mechanisms behind this effect are not fully understood. It is believed that the modulation of GABA and other neurotransmitter systems, as well as its effects on intracellular signaling pathways, contribute to its mood-stabilizing effects. Valproic acid may influence gene expression and cellular plasticity, which can lead to long-term changes in neuronal function and mood regulation. The combined effects on neurotransmitter balance, ion channel activity, and intracellular signaling pathways make VALANCE 250MG SOLUTION 100ML a versatile medication for managing seizures and mood disorders.

Common side effects of Valance (Valproic Acid) may include nausea, vomiting, diarrhea, stomach pain, indigestion, loss of appetite, changes in weight, hair loss, headache, dizziness, drowsiness, blurred vision or double vision, tremor, unsteadiness, problems with coordination, and nervousness. Less common but more serious side effects can include liver problems (such as jaundice, dark urine, pale stools), pancreatitis, unusual bleeding or bruising, severe allergic reactions (rash, itching, swelling), changes in mood or behavior (depression, suicidal thoughts), and decreased blood cell counts. In rare cases, Valance can cause hyperammonemia (elevated ammonia levels in the blood) leading to confusion or altered mental status. Contact your doctor immediately if you experience any serious or persistent side effects.

• If you miss a dose of VALANCE 250MG SOLUTION 100ML, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep VALANCE 250MG SOLUTION 100ML away from the reach of children and pets.
• Store VALANCE 250MG SOLUTION 100ML at room temperature.

• **Consistent Timing is Key:** Administer VALANCE 250MG SOLUTION 100ML at the same time(s) each day to maintain stable blood levels of valproic acid. This consistency helps in better seizure control and mood stabilization. Use an alarm or reminder app if needed.
• **Shake Well Before Use:** Always shake the VALANCE 250MG SOLUTION 100ML bottle well before measuring a dose. This ensures that the medication is evenly distributed throughout the solution, guaranteeing you receive the correct amount of medicine in each dose. Uneven distribution can lead to inconsistent therapeutic effects.
• **Accurate Dosage with a Measuring Device:** Use the provided measuring cup or syringe to measure each dose accurately. Kitchen spoons or other household measuring devices are often inaccurate and can lead to under- or overdosing. Consult your pharmacist if you need a replacement measuring device or clarification on how to use it.
• **Dietary Considerations:** While VALANCE 250MG SOLUTION 100ML can be taken with or without food, taking it with food may help reduce stomach upset, which is a common side effect. Be mindful of your overall diet and maintain a balanced intake of nutrients. Avoid excessive alcohol consumption, as it can interact with valproic acid and increase the risk of side effects.
• **Storage Matters:** Store VALANCE 250MG SOLUTION 100ML at room temperature, away from direct sunlight, heat, and moisture. Keep the bottle tightly closed when not in use. Proper storage helps maintain the medication's effectiveness and prevents degradation. Do not store it in the bathroom due to humidity.
• **Recognize Potential Side Effects:** Be aware of potential side effects such as nausea, vomiting, drowsiness, dizziness, or tremors. If these side effects become severe or persistent, contact your doctor immediately. Monitor for more serious side effects like liver problems (yellowing of skin or eyes), pancreatitis (severe abdominal pain), or unusual bleeding or bruising and seek prompt medical attention.
• **Do Not Stop Abruptly:** Do not stop taking VALANCE 250MG SOLUTION 100ML suddenly without consulting your doctor. Abruptly stopping the medication can increase the risk of seizures or worsen mood symptoms. Your doctor will gradually reduce the dose if it's necessary to discontinue the medication.
• **Medication Interactions:** Inform your doctor and pharmacist about all other medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Valproic acid can interact with other medications, potentially affecting their effectiveness or increasing the risk of side effects.
• **Regular Monitoring:** If you are taking VALANCE 250MG SOLUTION 100ML, your doctor will likely recommend regular blood tests to monitor your liver function and valproic acid levels. These tests help ensure that the medication is working effectively and that you are not experiencing any adverse effects.
• **Keep Out of Reach of Children:** As with all medications, keep VALANCE 250MG SOLUTION 100ML out of the reach of children and pets. Accidental ingestion can be dangerous. Store it in a secure location and dispose of any unused medication properly according to local regulations.

• While taking VALANCE 250MG SOLUTION 100ML, it is generally recommended to avoid consuming it with high-fat meals. Fatty foods can potentially decrease the absorption of the medicine, which might reduce its effectiveness. To ensure optimal absorption, take VALANCE 250MG SOLUTION 100ML at least one hour before or two hours after consuming meals, especially those high in fat content. Always follow your doctor's specific instructions regarding dietary considerations while on this medication.