VALKEM OD 250MG TABLET 10'S
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VALKEM OD 250MG TABLET 10'SVALKEM OD 250MG TABLET 10'SVALKEM OD 250MG TABLET 10'S
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VALKEM OD 250MG TABLET 10'S

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VALKEM OD 250MG TABLET 10'S

By ALKEM LABORATORIES LIMITED

MRP

122

₹103.7

15 % OFF

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About VALKEM OD 250MG TABLET 10'S

  • VALKEM OD 250MG TABLET 10'S is a medication primarily used to manage and control epileptic seizures. It contains valproic acid as its active ingredient, a well-established anticonvulsant that helps stabilize electrical activity in the brain, preventing seizures from occurring. The 'OD' in the name signifies 'Once Daily,' indicating that this formulation is designed for extended release, providing a consistent level of medication throughout the day with a single dose. This can improve patient compliance and simplify the treatment regimen.
  • Valproic acid works through multiple mechanisms of action, including increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter that helps to calm the brain's excitability. Additionally, valproic acid can affect sodium and calcium channels, further contributing to its anticonvulsant effects. By modulating these neuronal pathways, VALKEM OD helps to reduce the frequency and severity of seizures in individuals with epilepsy.
  • This medication is commonly prescribed for various types of seizures, including generalized seizures (such as tonic-clonic, absence, and myoclonic seizures) and partial seizures. It may also be used in the treatment of bipolar disorder to manage manic episodes. The extended-release formulation of VALKEM OD ensures a steady release of the drug, minimizing fluctuations in blood concentration levels and potentially reducing side effects associated with rapid peaks and troughs.
  • Before starting VALKEM OD, it's essential to inform your doctor about any pre-existing medical conditions, allergies, and other medications you are taking. Regular monitoring of liver function and blood counts may be necessary during treatment, as valproic acid can affect these parameters. Pregnant women should consult their doctor, as valproic acid may pose risks to the developing fetus. Adhering to the prescribed dosage and following your doctor's instructions carefully are crucial for the safe and effective use of this medication.

Uses of VALKEM OD 250MG TABLET 10'S

  • Control of seizures in epilepsy
  • Treatment of mania in bipolar disorder
  • Migraine prophylaxis
  • Treatment of neuropathic pain

How VALKEM OD 250MG TABLET 10'S Works

  • VALKEM OD 250MG TABLET 10'S contains Sodium Valproate as its active ingredient. Sodium Valproate is an anticonvulsant and mood-stabilizing medication that works through multiple mechanisms in the brain to control seizures and stabilize mood.
  • One primary way VALKEM OD works is by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter that helps to calm nerve activity. By boosting GABA levels, Sodium Valproate helps to reduce the excessive electrical activity in the brain that can lead to seizures. This calming effect contributes significantly to its anticonvulsant properties.
  • Additionally, Sodium Valproate affects voltage-gated ion channels, particularly sodium channels. These channels play a crucial role in the transmission of electrical signals along nerve cells. By modulating these channels, VALKEM OD helps to prevent the rapid and repetitive firing of neurons that characterize seizure activity. This modulation contributes to the drug's ability to control different types of seizures.
  • Furthermore, VALKEM OD also impacts other neurotransmitter systems. It can influence the levels of other neurotransmitters beyond GABA, contributing to its mood-stabilizing effects. The precise mechanisms by which it stabilizes mood are still being researched, but it is believed to involve a combination of neurotransmitter modulation and effects on intracellular signaling pathways.
  • The 'OD' in VALKEM OD 250MG TABLET 10'S stands for 'Once Daily' or 'Once a Day', indicating that this formulation is designed to release the medication gradually over an extended period. This extended-release mechanism helps to maintain a consistent level of Sodium Valproate in the bloodstream throughout the day, improving seizure control and reducing the likelihood of side effects associated with fluctuating drug levels. This controlled release is particularly beneficial for patients who require consistent medication levels to manage their condition effectively.
  • In summary, VALKEM OD 250MG TABLET 10'S works by increasing GABA levels, modulating voltage-gated sodium channels, and influencing other neurotransmitter systems in the brain. The extended-release formulation ensures a steady supply of the medication throughout the day, leading to more consistent seizure control and mood stabilization.

Side Effects of VALKEM OD 250MG TABLET 10'SArrow

Common side effects of VALKEM OD 250MG Tablet may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, headache, dizziness, drowsiness, and skin rash. Less common but potentially serious side effects include liver problems (such as jaundice, dark urine, persistent fatigue), pancreatitis (severe abdominal pain, nausea, vomiting), changes in mood or behavior, suicidal thoughts, and allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing). Contact your doctor immediately if you experience any serious side effects or if side effects persist or worsen.

Safety Advice for VALKEM OD 250MG TABLET 10'SArrow

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Allergies

Allergies

Use caution if you have any allergies to VALKEM OD 250MG TABLET 10'S. Consult your doctor.

Dosage of VALKEM OD 250MG TABLET 10'SArrow

  • The recommended dosage of VALKEM OD 250MG TABLET 10'S varies significantly depending on the individual's condition, its severity, and their response to the medication. It is crucial to adhere strictly to your physician's instructions regarding the dosage and timing of administration. Typically, the initial dose is lower, gradually increasing to achieve optimal therapeutic effects. This titration process helps minimize potential side effects and allows the body to adjust to the medication.
  • For adults, the starting dose might be 250mg once daily, preferably at night to reduce daytime drowsiness. The dosage may be increased incrementally every week or two, as determined by your doctor, based on your clinical response and tolerance. The maximum daily dose usually does not exceed 1500mg, but in some cases, a higher dose might be necessary under strict medical supervision. Always swallow the tablet whole with a glass of water, and do not crush, chew, or break it, as this can affect the medication's release and efficacy.
  • In elderly patients or those with impaired kidney or liver function, a lower starting dose and slower titration are often necessary to prevent adverse effects. Regular monitoring of kidney and liver function may be required during treatment. It's also important to inform your doctor about any other medications you are taking, as drug interactions can affect the dosage requirements. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Take 'VALKEM OD 250MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of VALKEM OD 250MG TABLET 10'S?Arrow

  • If you miss a dose of VALKEM OD 250MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store VALKEM OD 250MG TABLET 10'S?Arrow

  • Keep VALKEM OD 250MG TAB 1X10 away from the reach of children and pets.
  • Store VALKEM OD 250MG TAB 1X10 at room temperature.

Benefits of VALKEM OD 250MG TABLET 10'SArrow

  • VALKEM OD 250MG TABLET 10'S is a medication primarily used to manage and control seizures associated with epilepsy. Its extended-release formulation ensures a steady release of the active ingredient, valproic acid, throughout the day. This helps to maintain a consistent level of the drug in the bloodstream, reducing the frequency and severity of seizures more effectively compared to immediate-release formulations.
  • Beyond epilepsy, VALKEM OD 250MG TABLET 10'S is also prescribed for the treatment of bipolar disorder. It acts as a mood stabilizer, helping to manage the extreme mood swings characteristic of this condition. By regulating brain activity, valproic acid can reduce the occurrence of manic episodes (periods of elevated mood and energy) and depressive episodes (periods of profound sadness and loss of interest).
  • Moreover, VALKEM OD 250MG TABLET 10'S is often used as a prophylactic treatment for migraine headaches. It helps to reduce the frequency and intensity of migraine attacks. While the exact mechanism is not fully understood, it is believed that valproic acid affects certain neurotransmitters in the brain, thereby stabilizing nerve activity and preventing the onset of migraines.
  • The 'OD' in VALKEM OD signifies 'Once Daily,' highlighting the convenience of this formulation. A single daily dose simplifies the medication regimen, improving patient compliance and reducing the likelihood of missed doses. This is particularly beneficial for individuals who may have difficulty remembering multiple doses throughout the day.
  • The 250mg strength provides flexibility in dosing, allowing doctors to tailor the treatment to individual patient needs. Dosage adjustments can be made based on factors such as the patient's weight, age, and the severity of their condition. Regular monitoring and consultation with a healthcare professional are crucial to optimize the dosage and minimize potential side effects.
  • By effectively controlling seizures, VALKEM OD 250MG TABLET 10'S can significantly improve the quality of life for individuals with epilepsy, allowing them to lead more active and independent lives. Similarly, its mood-stabilizing properties can help those with bipolar disorder achieve greater emotional stability and improve their overall well-being. For migraine sufferers, reducing the frequency of attacks can lead to a substantial reduction in pain and disability.
  • Consistent use of VALKEM OD 250MG TABLET 10'S, as prescribed by a healthcare professional, is essential for achieving optimal therapeutic benefits. It's important to follow the doctor's instructions regarding dosage, timing, and any other recommendations to ensure the medication works effectively and safely.

How to use VALKEM OD 250MG TABLET 10'SArrow

  • VALKEM OD 250MG TABLET 10'S should be taken exactly as prescribed by your doctor. The dosage and frequency will depend on your specific condition and how you respond to the medication. It is crucial to adhere to the prescribed regimen for optimal results. Do not alter the dosage or discontinue the medication without consulting your healthcare provider, even if you start feeling better. Sudden discontinuation can lead to unwanted side effects or a recurrence of your symptoms.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect the way the medication is released into your system. VALKEM OD 250MG TABLET is typically designed for once-daily (OD) administration, meaning it should be taken at the same time each day. Consistency is key to maintaining a stable level of the medication in your body.
  • This medication can be taken with or without food. If you experience any stomach upset, taking it with food might help. However, it is important to maintain a consistent pattern regarding food intake (always with food or always without food) to ensure consistent absorption of the medication. Avoid taking it with alcohol, as it can potentially interact with the medication and worsen side effects.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you are unsure about what to do after missing a dose, consult your doctor or pharmacist for guidance.
  • Store VALKEM OD 250MG TABLET 10'S at room temperature, away from direct sunlight, heat, and moisture. Keep it out of the reach of children and pets. Before using, check the expiry date on the packaging. If the medication has expired, do not use it and dispose of it properly according to local regulations. Proper storage and handling are essential to maintain the efficacy and safety of the medication.
  • During the course of treatment with VALKEM OD 250MG TABLET, regular monitoring of liver function and blood counts may be required. Your doctor will advise you on the necessary tests and the frequency of these tests. These tests help to ensure the medication is working effectively and to detect any potential side effects early on.
  • Inform your doctor about all other medications, supplements, or herbal products you are currently taking. This will help avoid potential drug interactions. If you experience any unusual or severe side effects, such as allergic reactions, severe abdominal pain, jaundice, or any other concerning symptoms, seek immediate medical attention.

Quick Tips for VALKEM OD 250MG TABLET 10'SArrow

  • **Take VALKEM OD 250MG TABLET 10'S as prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not alter the dosage without consulting your healthcare provider. Taking it consistently as directed will help maintain a stable level of medication in your body, leading to better symptom control for conditions like epilepsy or bipolar disorder.
  • **Maintain a Consistent Routine:** Try to take VALKEM OD 250MG TABLET 10'S at the same time each day. This helps in adhering to the prescribed regimen and maximizes its effectiveness. Setting a daily reminder can be beneficial in remembering your dose. Consistency is crucial for managing your condition effectively.
  • **Be Aware of Potential Side Effects:** VALKEM OD 250MG TABLET 10'S may cause side effects such as nausea, vomiting, dizziness, or drowsiness. If these side effects persist or worsen, inform your doctor promptly. Understanding potential side effects allows for timely intervention and reduces unnecessary anxiety.
  • **Inform Your Doctor About Other Medications:** Before starting VALKEM OD 250MG TABLET 10'S, inform your doctor about all other medications, supplements, and herbal products you are taking. This prevents potential drug interactions, which could affect the efficacy of VALKEM OD 250MG TABLET 10'S or increase the risk of side effects. Accurate information ensures safe and effective treatment.
  • **Avoid Alcohol While Taking VALKEM OD 250MG TABLET 10'S:** Alcohol can increase the sedative effects of VALKEM OD 250MG TABLET 10'S and may also interfere with its effectiveness. It's advisable to avoid alcohol consumption to minimize potential risks and ensure optimal therapeutic outcomes. Discuss any concerns about alcohol use with your doctor.
  • **Store VALKEM OD 250MG TABLET 10'S Properly:** Store this medication at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Proper storage maintains the drug's integrity and effectiveness, ensuring you receive the full benefit of your medication.
  • **Do not stop taking the medicine abruptly:** Suddenly stopping VALKEM OD 250MG TABLET 10'S can lead to serious withdrawal symptoms, especially if you are taking it for epilepsy. Always consult your doctor before making any changes to your medication regimen. Gradual tapering of the dose, under medical supervision, is often necessary to prevent adverse effects.

FAQs

What is VALKEM OD 250MG TABLET 10'S?Arrow

VALKEM OD 250MG TABLET 10'S is a medication used to treat epilepsy and stabilize mood.

What is VALKEM OD 250MG TABLET 10'S used for?Arrow

It helps in the treatment of epilepsy, bipolar disorder, and migraines.

How does VALKEM OD 250MG TABLET 10'S work?Arrow

It works by reducing abnormal electrical activity in the brain.

What are the common side effects of VALKEM OD 250MG TABLET 10'S?Arrow

Common side effects include nausea, vomiting, diarrhea, dizziness, and fatigue.

How to store VALKEM OD 250MG TABLET 10'S?Arrow

Store it at room temperature, away from direct sunlight and moisture.

Should VALKEM OD 250MG TABLET 10'S be taken with food?Arrow

It can be taken with or without food, but it's better to take it with food to avoid stomach upset.

What happens if I miss a dose of VALKEM OD 250MG TABLET 10'S?Arrow

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

Can VALKEM OD 250MG TABLET 10'S interact with other medications?Arrow

Yes, it can interact with certain medications. Inform your doctor about all the medicines you are taking.

Can pregnant women take VALKEM OD 250MG TABLET 10'S?Arrow

Pregnant women should consult their doctor before taking VALKEM OD 250MG TABLET 10'S.

Can VALKEM OD 250MG TABLET 10'S cause weight gain?Arrow

Yes, weight gain can occur in some people taking VALKEM OD 250MG TABLET 10'S.

Is VALKEM OD 250MG TABLET 10'S a controlled substance?Arrow

No, VALKEM OD 250MG TABLET 10'S is not a controlled substance.

What are the symptoms of an overdose of VALKEM OD 250MG TABLET 10'S?Arrow

Symptoms of an overdose may include confusion, dizziness, drowsiness, and loss of consciousness.

Can I drink alcohol while taking VALKEM OD 250MG TABLET 10'S?Arrow

Alcohol should be avoided while taking VALKEM OD 250MG TABLET 10'S, as it can increase side effects.

What are the alternative brands for VALKEM OD 250MG TABLET 10'S?Arrow

Some alternative brands for VALKEM OD 250MG TABLET 10'S include Epival OD, Valparin, and Brical.

Can VALKEM OD 250MG TABLET 10'S be stopped abruptly?Arrow

VALKEM OD 250MG TABLET 10'S should not be stopped abruptly. It should always be discontinued gradually as per the doctor's advice.

References

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DrugBank: Valproic Acid (DB00272) - Comprehensive information on valproic acid, including its pharmacology, interactions, and uses.

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FDA Prescribing Information: Depakote (divalproex sodium) - Official FDA label providing detailed information about divalproex sodium, a related valproate product, including its indications, dosage, and safety information.

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NCBI Bookshelf: Valproate - StatPearls - Overview of valproate, its mechanism of action, pharmacokinetics, and clinical applications.

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European Medicines Agency: Valproate medicines: restrictions and pregnancy prevention programme - Information on valproate medicines, focusing on restrictions and pregnancy prevention programs due to teratogenic risks.

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UpToDate: Valproate: Beyond the basics - Clinical information on valproate for medical professionals; subscription required for full access, but abstracts are often informative.

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ALKEM LABORATORIES LIMITED

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