VALPROL CR 400MG TABLET 15'S
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VALPROL CR 400MG TABLET 15'SVALPROL CR 400MG TABLET 15'SVALPROL CR 400MG TABLET 15'SVALPROL CR 400MG TABLET 15'S
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VALPROL CR 400MG TABLET 15'S

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VALPROL CR 400MG TABLET 15'S

By INTAS PHARMACEUTICALS LIMITED

MRP

243

₹206.55

15 % OFF

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About VALPROL CR 400MG TABLET 15'S

  • VALPROL CR 400MG TABLET 15'S is a medication primarily used to manage epilepsy and bipolar disorder. It contains valproic acid as its active ingredient, a known mood stabilizer and anticonvulsant. This medication is formulated as a controlled-release tablet, which allows for a gradual release of the drug into the body, maintaining stable blood levels and reducing the frequency of doses needed per day.
  • The controlled-release mechanism is designed to minimize fluctuations in drug concentration, thereby decreasing potential side effects associated with peak levels and improving overall tolerability. VALPROL CR 400MG is particularly effective in controlling various types of seizures, including absence seizures, myoclonic seizures, and tonic-clonic seizures. It also plays a crucial role in preventing manic episodes in individuals diagnosed with bipolar disorder.
  • Valproic acid, the active ingredient, works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter that inhibits nerve impulses, thus calming the brain and reducing the likelihood of seizures and mood swings. Patients taking VALPROL CR 400MG should adhere strictly to their doctor's prescribed dosage and schedule to achieve optimal therapeutic outcomes. Regular monitoring of liver function and blood levels may be necessary during treatment to ensure safety and efficacy.
  • This medication should be used with caution in individuals with liver problems or a history of liver disease. It's also important to inform your healthcare provider about any other medications or supplements you are taking, as drug interactions can occur. Pregnant women should consult their doctor before using VALPROL CR 400MG, as it may pose risks to the developing fetus. Common side effects may include nausea, vomiting, drowsiness, and weight gain. If any unusual or severe symptoms occur, immediate medical attention should be sought.

Uses of VALPROL CR 400MG TABLET 15'S

  • Control of epileptic seizures
  • Treatment of mania (associated with bipolar disorder)
  • Migraine prophylaxis
  • Treatment of certain types of seizures (e.g., absence seizures, complex partial seizures)
  • Mood stabilization in bipolar disorder

How VALPROL CR 400MG TABLET 15'S Works

  • VALPROL CR 400MG TABLET 15'S contains valproic acid, a medication primarily used to treat epilepsy, bipolar disorder, and migraine headaches. Understanding how it works involves delving into its mechanisms within the brain.
  • In epilepsy, the brain experiences abnormal and excessive electrical activity, leading to seizures. Valproic acid is believed to work through multiple mechanisms to stabilize this activity. One key action is enhancing the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits nerve impulses in the brain. By increasing GABA's availability and effectiveness, valproic acid helps to dampen the excessive neuronal firing that causes seizures.
  • Additionally, valproic acid may also affect voltage-gated ion channels, specifically sodium and calcium channels. These channels play a crucial role in the transmission of electrical signals along neurons. By modulating these channels, valproic acid can further stabilize neuronal excitability and reduce the likelihood of seizures. The 'CR' in VALPROL CR stands for 'controlled release.' This formulation is designed to release the medication slowly and steadily over time, helping to maintain a more consistent level of the drug in the bloodstream and reduce fluctuations that could trigger side effects or breakthrough seizures.
  • In bipolar disorder, valproic acid acts as a mood stabilizer. While the exact mechanisms are not fully understood, it is thought to involve similar effects on GABA and ion channels, helping to regulate neuronal activity associated with mood swings. By stabilizing neuronal activity, valproic acid helps reduce the intensity and frequency of both manic and depressive episodes.
  • For migraine headaches, valproic acid is used as a preventative medication. It is thought that it may reduce the excitability of the brain that contributes to the development of migraines, again potentially through the modulation of GABA and ion channel function. The controlled-release formulation ensures a steady level of medication to help provide a stable baseline and reduce the likelihood of migraine onset. In summary, VALPROL CR 400MG TABLET 15'S, containing valproic acid, works through multiple pathways in the brain to stabilize neuronal activity, primarily by enhancing GABAergic inhibition and modulating sodium and calcium channels. This makes it effective in treating epilepsy, bipolar disorder, and migraine headaches.

Side Effects of VALPROL CR 400MG TABLET 15'SArrow

Common side effects of VALPROL CR 400MG TABLET may include nausea, vomiting, diarrhea, stomach pain, constipation, loss of appetite, headache, dizziness, drowsiness, weakness, tremors, blurred vision or double vision, hair loss, weight gain, changes in menstrual periods, and ringing in the ears. Less common but more serious side effects include liver problems (such as jaundice, dark urine, pale stools, persistent nausea or vomiting), pancreatitis (severe stomach pain, back pain), easy bruising or bleeding, changes in mood or behavior, suicidal thoughts, confusion, hallucinations, loss of coordination, swelling in the legs or feet, and allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing). Contact your doctor immediately if you experience any serious side effects.

Safety Advice for VALPROL CR 400MG TABLET 15'SArrow

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Allergies

Allergies

Do not take Valprol CR 400mg Tablet if you are allergic to valproic acid or divalproex sodium.

Dosage of VALPROL CR 400MG TABLET 15'SArrow

  • The dosage of VALPROL CR 400MG TABLET 15'S will be determined by your doctor based on your individual needs, medical condition, and response to treatment. It is crucial to adhere to the prescribed dosage and schedule. Do not alter the dosage or discontinue the medication without consulting your physician.
  • Generally, VALPROL CR is initiated at a low dose and gradually increased until the desired therapeutic effect is achieved. The typical starting dose for adults is 10-15 mg/kg/day, which may be increased by 5-10 mg/kg/day at weekly intervals until seizure control is achieved or side effects preclude further increases. The maximum recommended dose is 60 mg/kg/day. The total daily dose is usually divided into two or three doses.
  • For children, the dosage is also individualized based on weight and response to treatment. The usual starting dose is 15-45 mg/kg/day, divided into two or three doses. The maximum recommended dose is 60 mg/kg/day. It is important to monitor children closely for any signs of adverse effects.
  • VALPROL CR tablets should be swallowed whole and not crushed or chewed. They can be taken with or without food. If you experience stomach upset, taking it with food may help. If a dose is missed, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose to catch up. If you have any questions or concerns about your dosage, consult your doctor or pharmacist. Regular blood tests may be required to monitor the drug levels in your body and to assess liver function.
  • Take 'VALPROL CR 400MG TABLET 15'S' only as per the prescription by your physician only

What if I miss my dose of VALPROL CR 400MG TABLET 15'S?Arrow

  • If you miss a dose of VALPROL CR 400MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store VALPROL CR 400MG TABLET 15'S?Arrow

  • Keep VALPROL CR 400MG TAB 1X15 away from the reach of children and pets.
  • Store VALPROL CR 400MG TAB 1X15 at room temperature.

Benefits of VALPROL CR 400MG TABLET 15'SArrow

  • VALPROL CR 400MG TABLET 15'S is a medication primarily used to manage and control various types of seizures. It is highly effective in treating generalized seizures, including tonic-clonic (grand mal), absence, and myoclonic seizures. It helps stabilize electrical activity in the brain, reducing the frequency and intensity of seizures, thereby improving the quality of life for individuals with epilepsy.
  • This medication is a mood stabilizer, widely prescribed for managing bipolar disorder. It helps regulate mood swings, reducing the occurrence and severity of manic and depressive episodes. By stabilizing mood, it enables individuals with bipolar disorder to lead more balanced and productive lives.
  • VALPROL CR 400MG TABLET 15'S is also used as a prophylactic treatment for migraine headaches. It helps reduce the frequency and severity of migraine attacks. Regular use can significantly decrease the impact of migraines on daily life, allowing individuals to experience fewer headaches and improved overall well-being.
  • The controlled-release (CR) formulation of VALPROL ensures a steady release of the medication over an extended period. This helps maintain consistent blood levels, reducing fluctuations and minimizing the risk of breakthrough seizures or mood episodes. The CR formulation also often results in fewer side effects compared to immediate-release formulations.
  • Many individuals find VALPROL CR 400MG TABLET 15'S to be a convenient option due to its once- or twice-daily dosing schedule. This simplifies medication management and improves adherence to the prescribed treatment plan. The ease of use can lead to better outcomes and a more consistent therapeutic effect.
  • Beyond its primary uses, VALPROL has demonstrated effectiveness in managing certain types of nerve pain. While not its primary indication, it can be prescribed off-label to alleviate neuropathic pain conditions, providing relief for individuals who have not responded well to other treatments.
  • By effectively managing seizures, mood disorders, and migraines, VALPROL CR 400MG TABLET 15'S can significantly improve a person's overall quality of life. Reduced seizure frequency, stabilized mood, and fewer migraines can lead to increased independence, improved social functioning, and enhanced productivity in daily activities.
  • VALPROL's broad spectrum of activity makes it a valuable option for individuals who experience multiple conditions, such as epilepsy and bipolar disorder. It allows for a single medication to address multiple symptoms, simplifying treatment regimens and potentially reducing the need for multiple medications. This can improve adherence and reduce the risk of drug interactions.
  • When used appropriately under medical supervision, VALPROL can offer long-term benefits in managing chronic conditions like epilepsy, bipolar disorder, and migraines. Consistent use, as directed by a healthcare professional, can lead to sustained symptom control and improved long-term outcomes.
  • VALPROL can be used in combination with other medications to enhance its effectiveness. In some cases, combining VALPROL with other antiepileptic drugs or mood stabilizers can provide better control of symptoms than using a single medication alone. This combination therapy is carefully managed by healthcare professionals to optimize benefits and minimize potential risks.

How to use VALPROL CR 400MG TABLET 15'SArrow

  • VALPROL CR 400MG TABLET 15'S should be taken exactly as prescribed by your doctor. It is usually taken orally, with or without food. To minimize stomach upset, you may take it with food. Swallow the tablet whole with a glass of water; do not crush, chew, or break it, as this can affect how the medication is released in your body. The 'CR' in the name stands for controlled-release, meaning the medication is released slowly over time.
  • The dosage and frequency of VALPROL CR 400MG TABLET 15'S will depend on your specific condition, its severity, and how you respond to the treatment. Your doctor will determine the most appropriate dose for you. It's crucial to follow your doctor's instructions precisely and not adjust the dosage yourself. Do not stop taking the medication abruptly without consulting your doctor, as this can lead to withdrawal symptoms or a worsening of your condition. If you experience any side effects, inform your doctor promptly.
  • Consistency is key when taking VALPROL CR 400MG TABLET 15'S. Try to take it at the same time(s) each day to maintain a consistent level of the medication in your body. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. Proper storage is essential. Keep VALPROL CR 400MG TABLET 15'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. If you have any questions or concerns about how to use this medication, consult your doctor or pharmacist for clarification.

Quick Tips for VALPROL CR 400MG TABLET 15'SArrow

  • Take VALPROL CR 400MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting them, even if you feel better. Sudden discontinuation can lead to serious side effects.
  • VALPROL CR 400MG TABLET 15'S can be taken with or without food, but consistency is key. Choose a method and stick to it to ensure stable blood levels of the medication and optimal therapeutic effect. Taking it at the same time each day helps with this.
  • Be aware of potential side effects such as nausea, vomiting, stomach pain, indigestion, loss of appetite, diarrhea, headache, dizziness, drowsiness or sleepiness, unusual changes in mood or behavior, or unusual tiredness or weakness. If you experience any of these, consult your doctor immediately.
  • Inform your doctor about all other medications, herbal supplements, and vitamins you are taking. VALPROL CR 400MG TABLET 15'S can interact with other drugs, potentially altering their effects or increasing the risk of side effects. This includes over-the-counter medications.
  • Regular blood tests are important while taking VALPROL CR 400MG TABLET 15'S. Your doctor will monitor your liver function, blood cell counts, and valproic acid levels to ensure the medication is working effectively and to detect any potential problems early. Attend all scheduled appointments.
  • Avoid alcohol consumption while taking VALPROL CR 400MG TABLET 15'S, as it can increase drowsiness and dizziness, and may also increase the risk of liver damage. Always check with your doctor or pharmacist about alcohol consumption.
  • If you are planning to become pregnant, are pregnant, or are breastfeeding, discuss this with your doctor before taking VALPROL CR 400MG TABLET 15'S. This medicine can cause birth defects or harm to the baby. Effective birth control is recommended for women of childbearing age who are taking this medication.
  • Store VALPROL CR 400MG TABLET 15'S at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Proper storage helps maintain the drug's effectiveness and safety.
  • Maintain a healthy lifestyle, including a balanced diet, regular exercise, and adequate sleep. This can help improve your overall health and well-being while taking VALPROL CR 400MG TABLET 15'S and help manage your condition better.
  • Do not drive or operate heavy machinery until you know how VALPROL CR 400MG TABLET 15'S affects you. This medication can cause drowsiness or dizziness, which can impair your ability to perform tasks requiring alertness.

Food Interactions with VALPROL CR 400MG TABLET 15'SArrow

  • VALPROL CR 400MG TABLET 15'S can be taken with or without food, but it is recommended to take it consistently with or without food to maintain a stable level of the medication in your body.
  • Avoid alcohol consumption while taking VALPROL CR 400MG TABLET 15'S, as it can increase the risk of side effects such as drowsiness and liver problems.
  • If you experience stomach upset, taking VALPROL CR 400MG TABLET 15'S with food may help to reduce this. However, it's important to maintain consistency in whether you take it with food or not.

FAQs

What is Valprol CR 400mg Tablet used for?Arrow

Valprol CR 400mg Tablet is primarily used to treat epilepsy (seizures) and bipolar disorder. It may also help prevent certain types of headaches.

How does Valprol CR 400mg Tablet work?Arrow

Valprol CR 400mg Tablet works by reducing the abnormal and excessive activity of the nerve cells in the brain. It also works by increasing the levels of certain natural substances in the brain.

What are the common side effects of Valprol CR 400mg Tablet?Arrow

Common side effects of Valprol CR 400mg Tablet include nausea, vomiting, stomach pain, diarrhea, dizziness, drowsiness, and weight gain.

How should I store Valprol CR 400mg Tablet?Arrow

Store Valprol CR 400mg Tablet at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Is Valprol CR 400mg Tablet safe for pregnant women?Arrow

Valprol CR 400mg Tablet is not safe for use during pregnancy as it can harm the unborn baby. Talk to your doctor if you are pregnant or planning to become pregnant.

What are the symptoms of an overdose of Valprol CR 400mg Tablet?Arrow

Symptoms of an overdose of Valprol CR 400mg Tablet may include drowsiness, confusion, loss of muscle control, seizures, and coma.

Can Valprol CR 400mg Tablet be taken with or without food?Arrow

It is generally recommended to take Valprol CR 400mg Tablet with food to minimize the chance of stomach upset.

Is Valprol CR 400mg Tablet habit-forming?Arrow

No, Valprol CR 400mg Tablet is not habit-forming.

What happens if I miss a dose of Valprol CR 400mg Tablet?Arrow

If you miss a dose of Valprol CR 400mg Tablet, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can Valprol CR 400mg Tablet interact with other medications?Arrow

Yes, Valprol CR 400mg Tablet can interact with certain other medications. Tell your doctor about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins.

What is the difference between Valprol CR and Valproic Acid?Arrow

Valproic acid is the active ingredient in the medication. Valprol CR is a controlled-release formulation, meaning the medication is released slowly over time.

Can Valprol CR 400mg Tablet cause weight gain?Arrow

Yes, Valprol CR 400mg Tablet can cause weight gain in some people.

Can I drink alcohol while taking Valprol CR 400mg Tablet?Arrow

It is not recommended to drink alcohol while taking Valprol CR 400mg Tablet as it can increase side effects such as drowsiness and dizziness.

Is Valprol CR 400mg Tablet safe for children?Arrow

Valprol CR 400mg Tablet can be used to treat seizures and other conditions in children, but it should only be used under the supervision of a doctor.

How long does it take for Valprol CR 400mg Tablet to start working?Arrow

It may take a few weeks for Valprol CR 400mg Tablet to become fully effective.

References

Book Icon

DrugBank: Valproic Acid

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FDA Label: Depakote (valproate sodium) and Depakote ER (divalproex sodium) prescribing information

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PMC: A practical guide to the monitoring of valproic acid in neuropsychopharmacology

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PubChem: Valproic Acid

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Electronic Medicines Compendium (emc): Summary of Product Characteristics - Epilim CR Tablets

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INTAS PHARMACEUTICALS LIMITED

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India

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