VASCEL 20 INJECTION
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VASCEL 20 INJECTION
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VASCEL 20 INJECTION

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VASCEL 20 INJECTION

By CELON LABORATORIES LTD

MRP

152

₹95

37.5 % OFF

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Product DetailsArrow

Content Reviewed By:

Dr. Anil Gupta

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About VASCEL 20 INJECTION

  • VASCEL 20 INJECTION contains vasopressin, also known as antidiuretic hormone (ADH). It's a peptide hormone vital for maintaining water balance and regulating blood pressure. This medication is indicated for diabetes insipidus, a rare condition causing excessive thirst and urination due to insufficient ADH production or response. In specific cardiac arrest cases, VASCEL 20 INJECTION has served as an epinephrine alternative. It may also be used in severe hemorrhagic shock (life-threatening blood loss) to elevate blood pressure and support vital organ perfusion. Cardiac arrest is a critical, life-threatening event where the heart ceases beating, halting blood flow and causing unconsciousness.
  • This medication primarily regulates water balance and constricts blood vessels. During physical or emotional stress, it's released as part of the body's stress response, conserving water and increasing blood pressure. VASCEL 20 INJECTION has also been linked to social behaviors and bonding in certain animal species, including pair bonding and maternal behaviors. VASCEL 20 INJECTION is a synthetic form of vasopressin, used to treat a deficiency of vasopressin. It is used to control blood pressure in people with certain types of shock and also to treat diabetes insipidus.
  • Administration of VASCEL 20 INJECTION requires careful monitoring due to potential allergic reactions or other adverse effects. The drug's water-retaining effects may lead to hyponatremia (low sodium levels) if not monitored closely. Its vasoconstrictive properties can significantly increase blood pressure; thus, caution is advised for patients with hypertension or cardiovascular conditions. Dosage adjustments and monitoring are also essential in pediatric and elderly patients.

Uses of VASCEL 20 INJECTION

  • VASCEL 20 INJECTION is used to treat the following: Diabetes Insipidus. This is a condition where the body doesn't produce enough vasopressin, leading to excessive thirst and frequent urination.
  • Cardiac Arrest: VASCEL 20 INJECTION is used during cardiac arrest to help restart the heart and restore blood circulation. It helps to constrict blood vessels and improve blood flow to the heart and brain.
  • Hemorrhagic Shock: VASCEL 20 INJECTION is used to treat hemorrhagic shock, which is caused by severe blood loss. It helps to increase blood pressure by constricting blood vessels, thereby helping to maintain blood flow to vital organs.

Side Effects of VASCEL 20 INJECTIONArrow

Like all medications, VASCEL 20 INJECTION can cause side effects, although not everyone experiences them.

  • Allergic reactions
  • Chest pain or irregular heartbeats
  • Severe headache
  • Confusion
  • Changes in mental state
  • Seizures
  • Severe abdominal pain or cramping
  • Nausea or vomiting
  • Stomach cramps
  • Headache
  • Dizziness or lightheadedness
  • Runny or stuffy nose
  • Increased thirst
  • Water retention or swelling

Safety Advice for VASCEL 20 INJECTIONArrow

breast_feeding

BreastFeeding

CONSULT YOUR DOCTOR

The safety of VASCEL 20 INJECTION during breastfeeding is not well-established, and its use should be approached with caution. Before using this medication while breastfeeding, healthcare providers should be consulted.

driving

Driving

UNSAFE

The safety of driving while taking VASCEL 20 INJECTION can vary depending on individual responses to the medication. It may cause side effects such as dizziness, drowsiness, or blurred vision, impairing driving ability.

liver

Liver Function

CONSULT YOUR DOCTOR

Caution should be exercised when using VASCEL 20 INJECTION in patients with liver conditions, as impaired liver function may affect drug metabolism.

lungs

Lungs

CONSULT YOUR DOCTOR

Regarding VASCEL 20 INJECTION, it is crucial to exercise caution when using this medication in patients with lung-related conditions, as it can potentially cause or worsen lung-related complications.

pregnancy

Pregnancy

CONSULT YOUR DOCTOR

During pregnancy, VASCEL 20 INJECTION should only be used when necessary and under the guidance of a healthcare professional. Close monitoring and consideration of potential risks are essential to ensure the well-being of both the mother and the baby.

Dosage of VASCEL 20 INJECTIONArrow

  • VASCEL 20 INJECTION offers versatility in its administration, allowing healthcare providers to select the most appropriate route based on the patient's specific needs and the nature of their condition. The available routes include intravenous (IV) injection, which delivers the medication directly into the bloodstream for rapid onset of action. Intramuscular (IM) injection, where the medication is injected into a muscle, provides a slightly slower but sustained release. Subcutaneous (SC) injection involves injecting the medication under the skin, offering another option for slower absorption. In certain situations, intranasal administration may also be considered.
  • The choice of administration route is crucial in determining how quickly and effectively the medication works. IV administration is often preferred in emergency situations where immediate effects are required. IM and SC injections are suitable for longer-term treatment plans where a steady release of the medication is desired. Intranasal administration may be used for ease of delivery and rapid absorption through the nasal mucosa.
  • Regardless of the chosen route, it is imperative that VASCEL 20 INJECTION be administered by trained healthcare professionals. This ensures that the injection is given correctly, at the appropriate dosage, and with careful monitoring for any potential adverse reactions. Self-administration is strongly discouraged, as it can lead to complications and reduced effectiveness of the treatment. Healthcare professionals are equipped to manage any unexpected events and provide the necessary support to the patient throughout the administration process.

How to store VASCEL 20 INJECTION?Arrow

  • Keep VASCEL 20MG INJ 1ML away from the reach of children and pets.
  • Store VASCEL 20MG INJ 1ML in a refrigerator (2 - 8°C). Do not freeze.

Benefits of VASCEL 20 INJECTIONArrow

  • VASCEL 20 INJECTION works through a dual mechanism, primarily focusing on the kidneys and blood vessels. In individuals with diabetes insipidus, it selectively binds to V2 receptors located in the kidneys. This interaction enhances water reabsorption, leading to a reduction in urine production and helping to restore fluid balance within the body. This targeted action is crucial in managing the excessive thirst and frequent urination associated with this condition.
  • During cardiac arrest scenarios, VASCEL 20 INJECTION shifts its focus to V1 receptors found on blood vessels. By binding to these receptors, it triggers vasoconstriction, causing the blood vessels to narrow. This vasoconstrictive effect leads to an elevation in blood pressure, which is vital for improving blood flow to critical organs during resuscitation efforts. Improved blood flow ensures that the heart and brain receive the oxygen and nutrients they need to function.
  • In cases of severe hemorrhagic shock, where significant blood loss leads to dangerously low blood pressure, VASCEL 20 INJECTION's vasoconstrictive properties become essential. By constricting blood vessels, it helps maintain blood pressure and supports the perfusion of vital organs, preventing organ damage due to lack of oxygen and nutrients. This action provides crucial support until definitive treatment, such as blood transfusions or surgical intervention, can be administered to address the underlying cause of the bleeding. Given its potent cardiovascular effects, careful monitoring and precise dosing are of paramount importance to avoid potential complications.

How to use VASCEL 20 INJECTIONArrow

  • VASCEL 20 INJECTION offers versatility in its administration, allowing healthcare providers to choose the most suitable route based on the patient's specific needs and medical circumstances. These routes encompass intravenous (IV) administration, which delivers the medication directly into the bloodstream for rapid onset of action, intramuscular (IM) injection, which provides a slower but sustained release of the drug, and subcutaneous (SC) injection, which allows for absorption through the tissues beneath the skin.
  • In certain situations, VASCEL 20 INJECTION may also be administered intranasally, offering a non-invasive alternative that can be particularly useful in emergency settings or when IV access is challenging. The selection of the optimal route depends on factors such as the desired speed of effect, the patient's condition, and the availability of resources.
  • Regardless of the chosen route, it is crucial that VASCEL 20 INJECTION be administered under the strict supervision of qualified healthcare professionals. This ensures accurate dosing, proper technique, and prompt management of any potential adverse reactions. Healthcare providers are trained to assess the patient's response to the medication and make any necessary adjustments to optimize its effectiveness and safety. Self-administration is strongly discouraged due to the potential risks involved.

FAQs

What should I do if I miss a dose of VASCEL 20 INJECTION?Arrow

If you miss a dose of VASCEL 20 INJECTION, contact your healthcare provider for guidance on what to do. Do not double the dose to make up for the missed one.

Can VASCEL 20 INJECTION cause electrolyte imbalances?Arrow

VASCEL 20 INJECTION can cause hyponatremia (low sodium levels) due to its water-retaining effects. Monitoring electrolyte levels is important, especially in patients at risk of imbalances.

Can VASCEL 20 INJECTION be used to treat septic shock?Arrow

While VASCEL 20 INJECTION has been studied to treat septic shock, it is not the first-line treatment and should be used with caution and under the supervision of a healthcare professional.

Can VASCEL 20 INJECTION be used to stop bleeding during surgery?Arrow

VASCEL 20 INJECTION has been used to reduce bleeding during specific surgical procedures due to its vasoconstrictive effects. However, it should be administered by experienced healthcare professionals to avoid complications.

Is there a risk of dependency on long-term VASCEL 20 INJECTION use?Arrow

VASCEL 20 INJECTION replacement therapy for diabetes insipidus is not typically associated with dependency. However, it is essential to follow the prescribed treatment plan and regular medical check-ups.

Can VASCEL 20 INJECTION cause water intoxication?Arrow

Excessive VASCEL 20 INJECTION administration can lead to water retention and potentially cause water intoxication, leading to electrolyte imbalances. Proper dosing and monitoring are crucial to avoid this complication.

Is there any interaction of VASCEL 20 INJECTION with other drugs?Arrow

There is NULL interaction of VASCEL 20 INJECTION with other drugs

What advice should I follow while using VASCEL 20 INJECTION?Arrow

Caution should be exercised to monitor for severe allergic reactions, cardiovascular effects, and hyponatremia. Special care is required for patients with hepatic or renal impairment, the elderly, and pediatric patients, as they may have altered responses. During pregnancy and breastfeeding, the use of VASCEL 20 INJECTION should be approached cautiously, and potential drug interactions need to be considered. Excessive dosing or prolonged use might lead to tolerance and overdose risks. Patients with cardiovascular diseases, allergies to oxytocin, or epilepsy require close monitoring. Proper administration, dilution, and monitoring of intravenous infusions are essential, and intranasal formulations must adhere to recommended dosages to avoid complications. Awareness of the risk of water intoxication and gangrene is crucial, as is monitoring peripheral circulation. Careful assessment and active patient involvement are fundamental in ensuring the safe and effective use of this medication.

What is Vasopressin and why is it used in VASCEL 20 INJECTION?Arrow

VASOPRESSIN is molecule/combination used for making VASCEL 20 INJECTION.

For what conditions in Endocrinology is VASCEL 20 INJECTION prescribed?Arrow

VASCEL 20 INJECTION is prescribed for Endocrinology related conditions.

For what conditions in Nephrology is VASCEL 20 INJECTION prescribed?Arrow

VASCEL 20 INJECTION is prescribed for Nephrology related conditions.

References

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Mercury Pharmaceutical Ltd, Electronic medicines compendium (EMC)

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American Regent, US Food and Drug Administration

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CELON LABORATORIES LTD

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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