vasograin ec tablet 20's
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VASOGRAIN EC TABLET 20'S

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VASOGRAIN EC TABLET 20'S

By CADILA PHARMACEUTICALS PRIVATE LIMITED

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217

₹184.45

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Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About VASOGRAIN EC TABLET 20'S

  • Vasograin EC Tablet is a prescription combination medicine primarily used for the acute treatment of migraine attacks, with or without aura. It typically contains ergotamine tartrate and caffeine, and in some formulations may be combined with additional analgesic or antiemetic components as per the manufacturer. The “EC” usually denotes enteric-coated tablets, designed to dissolve in the intestine rather than the stomach, which may help reduce gastric irritation in some patients. Vasograin EC Tablet is not intended for everyday headache or for prevention of migraine; it is meant to be taken at the onset of a migraine attack, strictly as directed by a registered medical practitioner. Ergotamine acts by constricting dilated cranial blood vessels and inhibiting the release of certain inflammatory neuropeptides involved in migraine pathophysiology. Caffeine enhances the absorption and effect of ergotamine and itself has mild vasoconstrictor and analgesic adjuvant properties. Together, these actions can help relieve throbbing headache, associated nausea, vomiting, and sensitivity to light and sound in many patients. However, ergotamine-containing products have a narrow safety margin and a well‑defined maximum allowable intake over 24 hours and per week; exceeding these limits can lead to serious toxicity, including severe vasospasm and reduced blood flow to limbs or vital organs. For this reason, the exact dose, timing, and maximum frequency must be individualized and clearly explained by the prescriber, and patients should never self‑adjust the dose. Vasograin EC Tablet is generally reserved for patients with diagnosed migraine who have not responded adequately to simple analgesics or non‑steroidal anti‑inflammatory drugs. It is not suitable for tension‑type headaches, cluster headaches without specialist advice, or undiagnosed sudden severe headaches. The medicine is contraindicated in several conditions, including significant cardiovascular disease, uncontrolled hypertension, peripheral vascular disease, severe liver or kidney impairment, sepsis, and in combination with certain interacting drugs such as potent CYP3A4 inhibitors, some macrolide antibiotics, and protease inhibitors, due to the risk of ergotism. It must not be used in pregnancy or during breastfeeding because ergotamine can cause uterine contractions, reduced placental blood flow, and serious harm to the infant. Common adverse effects may include nausea, vomiting, abdominal discomfort, dizziness, tingling or numbness in fingers and toes, muscle pain, and transient increase in blood pressure. More serious symptoms such as severe limb pain, cold or pale extremities, chest pain, shortness of breath, confusion, or sudden weakness require immediate medical attention and discontinuation of the drug. Long‑term or very frequent use can lead to medication‑overuse headache and dependence‑like patterns, where headache becomes more frequent and less responsive to treatment. Patients should keep a headache diary and review their overall migraine management plan regularly with their clinician, including lifestyle measures and preventive therapies where appropriate. Because of its risk profile, Vasograin EC Tablet should only be used under close medical supervision, with careful assessment of cardiovascular risk factors, concomitant medications, and comorbidities. Patients should be counselled about early recognition of toxicity, the importance of not exceeding the prescribed number of tablets in a day or week, and the need to avoid other ergot derivatives or triptans within the specified washout periods. This information is general and may not cover all brand‑specific details; patients must follow the instructions on the package insert and those provided by their treating physician or pharmacist.

Uses of VASOGRAIN EC TABLET 20'S

  • Treatment of Migraine
  • Relief from Headaches
  • Reducing the Frequency of Migraine Attacks
  • Managing Migraine Symptoms like Nausea and Vomiting
  • Relieving Headaches by Constricting Blood Vessels

How VASOGRAIN EC TABLET 20'S Works

  • VASOGRAIN EC Tablet 20's is a combination medicine primarily used to treat migraine headaches. It contains three active ingredients: Ergotamine, Caffeine, and Prochlorperazine. Each ingredient works in a specific way to alleviate migraine symptoms.
  • Ergotamine is a vasoconstrictor. It works by narrowing the blood vessels in the head that have become widened, which is believed to be a major cause of migraine headaches. By constricting these blood vessels, ergotamine helps to reduce the throbbing pain associated with migraines. It directly addresses the vascular component of the migraine.
  • Caffeine acts as an adjuvant to ergotamine. It enhances the effects of ergotamine, making it more effective in relieving migraine pain. Caffeine also has its own analgesic properties, which can further contribute to headache relief. Furthermore, caffeine helps in faster absorption of ergotamine by the body.
  • Prochlorperazine is an antiemetic, meaning it helps to relieve nausea and vomiting. Migraines are often accompanied by these symptoms, and prochlorperazine helps to manage them. It works by blocking dopamine receptors in the brain, which reduces the signals that trigger nausea and vomiting.
  • In summary, VASOGRAIN EC Tablet 20's works through a multi-pronged approach: Ergotamine constricts blood vessels to reduce headache pain, caffeine enhances ergotamine's effects and provides additional pain relief, and prochlorperazine alleviates nausea and vomiting associated with migraines. The combination of these three active ingredients provides comprehensive relief from migraine symptoms.

Side Effects of VASOGRAIN EC TABLET 20'SArrow

Possible side effects of Vasograin EC Tablet may include: * Nausea * Vomiting * Dizziness * Drowsiness * Abdominal discomfort * Muscle cramps * Weakness * Changes in blood pressure * Allergic reactions (rash, itching, swelling) * Heartburn * Visual disturbances * Numbness or tingling * Headache * Fatigue * Dry mouth This is not an exhaustive list. If you experience any unusual symptoms while taking Vasograin EC Tablet, consult your doctor immediately.

Safety Advice for VASOGRAIN EC TABLET 20'SArrow

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Heart and circulation

Use with extreme caution or avoid

Because ergotamine causes vasoconstriction, Vasograin EC Tablet is contraindicated in patients with coronary artery disease, history of myocardial infarction, angina, peripheral arterial disease, uncontrolled hypertension, or severe cerebrovascular disease.

Dosage of VASOGRAIN EC TABLET 20'SArrow

  • The recommended dosage of VASOGRAIN EC TABLET 20'S varies depending on the individual's condition and response to treatment. It is crucial to adhere strictly to your doctor's prescribed dosage and schedule. Typically, the starting dose is one tablet taken at the onset of migraine symptoms. If symptoms persist or recur, a second tablet may be taken, usually with an interval of at least two hours between doses. Do not exceed the maximum daily dose prescribed by your physician.
  • It is essential to swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this may affect the way the medication is released and absorbed. Taking VASOGRAIN EC TABLET 20'S with food may help to reduce stomach upset in some individuals. However, the medication can be taken with or without food as per your doctor's instructions.
  • For prophylactic or preventive treatment, your doctor will determine the appropriate dosage and frequency based on your specific needs. Regular monitoring and follow-up appointments are important to assess the effectiveness of the treatment and make any necessary adjustments to the dosage. Always inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as drug interactions may occur. Long-term use of VASOGRAIN EC TABLET 20'S should be under strict medical supervision to minimize potential side effects. If you experience any adverse reactions, such as nausea, vomiting, dizziness, or allergic reactions, seek immediate medical attention. Take 'VASOGRAIN EC TABLET 20'S' only as per the prescription by your physician only.

What if I miss my dose of VASOGRAIN EC TABLET 20'S?Arrow

  • If you miss a dose of Vasograin EC Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store VASOGRAIN EC TABLET 20'S?Arrow

  • Keep VASOGRAIN EC TAB 1X20 away from the reach of children and pets.
  • Store VASOGRAIN EC TAB 1X20 at room temperature.

Benefits of VASOGRAIN EC TABLET 20'SArrow

  • VASOGRAIN EC Tablet 20's is a comprehensive medication specifically formulated to alleviate the debilitating symptoms associated with migraines and other vascular headaches. Its multi-pronged approach targets the underlying causes and manifestations of these headaches, providing significant relief and improving the quality of life for sufferers. The key benefits include:
  • <b>Effective Migraine Relief:</b> VASOGRAIN EC provides rapid and effective relief from acute migraine attacks. It helps to reduce the severity and duration of headache pain, allowing individuals to resume their daily activities more quickly.
  • <b>Reduces Nausea and Vomiting:</b> Many migraine sufferers experience nausea and vomiting as part of their symptoms. VASOGRAIN EC contains ingredients that help to alleviate these symptoms, providing additional comfort during a migraine attack.
  • <b>Controls Throbbing Headaches:</b> The formulation effectively combats throbbing headaches, a common characteristic of migraines, by constricting the blood vessels responsible for the pulsating pain.
  • <b>Prevents Aura Symptoms:</b> For individuals who experience aura symptoms (visual disturbances, sensory changes) before a migraine, VASOGRAIN EC can help to lessen the intensity and duration of these pre-headache symptoms.
  • <b>Relieves Sensitivity to Light and Sound:</b> During a migraine, sensitivity to light (photophobia) and sound (phonophobia) can be intense. VASOGRAIN EC helps to reduce these sensitivities, making the migraine attack more manageable.
  • <b>Improves Overall Well-being:</b> By effectively managing migraine symptoms, VASOGRAIN EC contributes to an overall improvement in well-being. Reduced pain, nausea, and sensitivity to stimuli can lead to increased energy levels and a better mood.
  • <b>Reduces Dependence on Painkillers:</b> Regular use of VASOGRAIN EC, as prescribed by a doctor, can potentially reduce the need for over-the-counter painkillers, minimizing the risk of side effects associated with their overuse.
  • <b>Enhances Productivity:</b> By quickly relieving migraine symptoms, VASOGRAIN EC enables individuals to return to work or other activities sooner, enhancing their overall productivity and reducing lost time.
  • <b>Improves Sleep Quality:</b> Migraines can significantly disrupt sleep. By managing migraine symptoms, VASOGRAIN EC can contribute to improved sleep quality, leading to greater daytime alertness and cognitive function.
  • <b>Reduces Frequency of Migraine Attacks:</b> While primarily used for acute migraine relief, some components of VASOGRAIN EC may contribute to a reduction in the frequency of migraine attacks over time, especially when used as part of a comprehensive migraine management plan.
  • <b>Easy to Administer:</b> VASOGRAIN EC tablets are easy to swallow and administer, making them a convenient option for individuals seeking quick relief from migraine symptoms.
  • <b>Suitable for Various Types of Vascular Headaches:</b> Besides migraines, VASOGRAIN EC can also be effective in treating other types of vascular headaches, providing a broader range of relief for headache sufferers.
  • <b>Enhances Focus and Concentration:</b> Migraines can severely impair focus and concentration. By relieving the pain and associated symptoms, VASOGRAIN EC helps to restore mental clarity and improve cognitive performance.
  • <b>Improved Quality of Life:</b> The cumulative effect of all the benefits of VASOGRAIN EC is a significant improvement in the overall quality of life for migraine sufferers. It allows them to participate more fully in daily activities, social events, and personal pursuits without the constant fear of a debilitating headache.

How to use VASOGRAIN EC TABLET 20'SArrow

  • VASOGRAIN EC TABLET 20'S is designed for oral administration. It is crucial to adhere to your doctor's prescribed dosage and duration of treatment. Do not exceed the recommended dose, as this could increase the risk of side effects without providing additional benefit. Swallow the tablet whole with a full glass of water. Avoid crushing, chewing, or breaking the tablet, as this may affect the way the medication is released into your system.
  • It is generally recommended to take VASOGRAIN EC TABLET 20'S at the first sign of a migraine or headache to achieve optimal results. However, your doctor may advise you to take it at a different time, depending on your specific condition and treatment plan. Follow your doctor's instructions precisely.
  • Consistency is key for managing migraines effectively. Try to take VASOGRAIN EC TABLET 20'S around the same time each day, if you are taking it regularly. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Inform your doctor about any other medications, supplements, or herbal products you are currently taking, as they may interact with VASOGRAIN EC TABLET 20'S. Also, let your doctor know if you have any pre-existing medical conditions, especially heart problems, high blood pressure, liver disease, or kidney disease. Pregnant or breastfeeding women should consult their doctor before using this medication.
  • If your symptoms worsen or do not improve after taking VASOGRAIN EC TABLET 20'S, consult your doctor promptly. Long-term use of VASOGRAIN EC TABLET 20'S should be under strict medical supervision, as it may lead to certain side effects. Store VASOGRAIN EC TABLET 20'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Quick Tips for VASOGRAIN EC TABLET 20'SArrow

Food Interactions with VASOGRAIN EC TABLET 20'SArrow

  • VASOGRAIN EC TABLET 20'S is generally taken without food. However, if you experience stomach upset, you can take it with food. Avoid consuming large amounts of caffeine (e.g., coffee, tea, chocolate) as it may interfere with the medication's effectiveness or increase side effects. Also, limit alcohol consumption as it can worsen certain side effects like drowsiness or dizziness.

FAQs

What are the main uses of Vasograin EC Tablet?Arrow

Vasograin EC Tablet is primarily used for the acute treatment of migraine attacks, with or without aura, in adults who have been properly diagnosed with migraine by a healthcare professional. It helps relieve the throbbing headache and associated symptoms such as nausea, vomiting, and sensitivity to light and sound. It is not intended for routine treatment of common headaches, tension‑type headaches, or for prevention of migraine attacks.

How does Vasograin EC Tablet work in migraine?Arrow

Vasograin EC Tablet usually contains ergotamine tartrate and caffeine. Ergotamine constricts dilated cranial blood vessels and inhibits the release of inflammatory neuropeptides involved in migraine. Caffeine enhances the absorption and effect of ergotamine and has mild vasoconstrictor and adjuvant analgesic properties. Together, these actions reduce the vascular and neurogenic components of a migraine attack, thereby decreasing headache intensity and associated symptoms.

Can Vasograin EC Tablet be used to prevent migraine attacks?Arrow

No. Vasograin EC Tablet is not a preventive or prophylactic medicine for migraine. It is intended only for the acute treatment of an ongoing migraine attack and should be taken at the earliest sign of migraine, exactly as prescribed. For prevention of frequent or severe migraines, other medications such as beta‑blockers, certain antiepileptics, antidepressants, or CGRP‑targeted therapies may be considered by your doctor based on your clinical profile.

How and when should I take Vasograin EC Tablet?Arrow

The exact dose, timing, and maximum number of Vasograin EC Tablets per day or per week must be decided by your doctor, based on your age, medical history, and severity of migraine. Generally, it is taken orally with water at the onset of a migraine attack. Do not chew or crush enteric‑coated tablets unless advised. Never exceed the maximum daily or weekly dose specified by your prescriber, and do not repeat doses more frequently than recommended. If you are unsure about your dosing schedule, consult your doctor or pharmacist before taking the medicine.

What are the common side effects of Vasograin EC Tablet?Arrow

Common side effects may include nausea, vomiting, abdominal discomfort, dizziness, drowsiness, fatigue, mild increase in blood pressure, and tingling or numbness in fingers and toes. Some people may experience muscle pain or a feeling of coldness in the extremities. These effects are usually dose‑related. If side effects are persistent, bothersome, or worsen, you should contact your doctor. Any sudden or severe symptoms such as chest pain, severe limb pain, marked pallor or bluish discoloration of fingers or toes, or difficulty breathing require urgent medical attention.

Who should not take Vasograin EC Tablet?Arrow

Vasograin EC Tablet is contraindicated in people with known hypersensitivity to ergotamine, caffeine, or any excipients in the formulation; those with coronary artery disease, history of heart attack, angina, peripheral vascular disease, uncontrolled hypertension, severe liver or kidney impairment, sepsis, or severe systemic infections. It must not be used in pregnancy or during breastfeeding. It is also contraindicated in patients taking potent CYP3A4 inhibitors, certain macrolide antibiotics, some antifungals, protease inhibitors, or other ergot derivatives, due to the risk of serious vasospasm and ergotism. Always inform your doctor about your full medical history before starting this medicine.

Can I take Vasograin EC Tablet with other migraine medicines like triptans?Arrow

Vasograin EC Tablet should not be taken together with triptans (such as sumatriptan, rizatriptan, zolmitriptan) or within a specified interval before or after triptan use, because the combination can cause excessive vasoconstriction and increase the risk of serious cardiovascular events. Your doctor will advise an appropriate washout period between ergotamine‑containing products and triptans. Do not combine Vasograin EC Tablet with other ergot derivatives or over‑the‑counter migraine remedies without medical advice.

Is Vasograin EC Tablet safe during pregnancy or while trying to conceive?Arrow

Vasograin EC Tablet is contraindicated in pregnancy because ergotamine can cause uterine contractions, reduced placental blood flow, and may lead to miscarriage, fetal distress, or other serious complications. It should also be avoided in women planning pregnancy or those who may be pregnant but not yet confirmed. If you become pregnant or suspect pregnancy while taking this medicine, stop using it and contact your doctor immediately. Your doctor can recommend safer alternatives for migraine management during pregnancy.

Can I use Vasograin EC Tablet while breastfeeding?Arrow

No. Vasograin EC Tablet should not be used during breastfeeding. Ergotamine can pass into breast milk and may cause serious adverse effects in the nursing infant, including vomiting, diarrhea, weak pulse, unstable blood pressure, and possible suppression of lactation. If treatment with an ergotamine‑containing product is considered essential, breastfeeding should be discontinued, and you should discuss alternative feeding options and safer migraine treatments with your doctor.

What precautions should I take while using Vasograin EC Tablet?Arrow

Use Vasograin EC Tablet only as prescribed and do not exceed the recommended daily or weekly limits. Inform your doctor about any history of heart disease, stroke, peripheral vascular disease, high blood pressure, liver or kidney problems, smoking, or use of hormonal contraceptives, as these factors may increase the risk of vascular side effects. Avoid combining this medicine with strong CYP3A4 inhibitors, other ergot derivatives, or triptans. Limit or avoid alcohol, monitor for symptoms such as severe limb pain, cold or pale extremities, chest pain, or shortness of breath, and seek immediate medical help if they occur. Do not use the medicine for undiagnosed headaches or on more days per month than your doctor recommends, to reduce the risk of medication‑overuse headache.

What should I do if Vasograin EC Tablet does not relieve my migraine?Arrow

If a prescribed dose of Vasograin EC Tablet does not provide adequate relief, do not take extra tablets or repeat the dose sooner than advised, as this can increase the risk of serious side effects. Instead, follow the rescue plan given by your doctor, which may include alternative medications or non‑drug measures. If your migraines frequently fail to respond to the prescribed regimen, or if the pattern of your headaches changes (for example, they become more severe, more frequent, or different in character), consult your doctor promptly for reassessment and possible adjustment of your treatment plan.

References

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Dihydroergotamine - DrugBank Online. This provides information on dihydroergotamine, a common ingredient in migraine medications. It includes details on its mechanism of action, uses, and potential side effects.

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Acetaminophen (Paracetamol) - A Review of Biochemistry, the Mechanism of Action, Recent Advancements and Future Perspectives. This resource offers details on acetaminophen's mechanism, uses, and biochemical properties.

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FDA Label for CAFERGOT (ergotamine tartrate and caffeine) tablets, for oral use. This is a combined medication, used for the treatment of migraine headaches

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Ergotamine - an overview. ScienceDirect Topics. This resource provides an overview of ergotamine, including its pharmacology, uses, and potential adverse effects.

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Caffeine - StatPearls - NCBI Bookshelf. Information about caffeine's effects, mechanism of action, and potential side effects.

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